LOCUS       NC_000964               2941 bp    DNA     linear   CON 18-SEP-2018
DEFINITION  Bacillus subtilis subsp. subtilis str. 168 complete genome.
ACCESSION   NC_000964
VERSION     NC_000964.3
DBLINK      BioProject: PRJNA76
            BioSample: SAMEA3138188
KEYWORDS    RefSeq; complete genome.
SOURCE      Bacillus subtilis subsp. subtilis str. 168
  ORGANISM  Bacillus subtilis subsp. subtilis str. 168
            Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1
  AUTHORS   Borriss,R., Danchin,A., Harwood,C.R., Medigue,C., Rocha,E.P.C.,
            Sekowska,A. and Vallenet,D.
  TITLE     Bacillus subtilis, the model Gram-positive bacterium: 20 years of
            annotation refinement
  JOURNAL   Microb Biotechnol 11 (1), 3-17 (2018)
   PUBMED   29280348
REFERENCE   2  (bases 1 to 2941)
  AUTHORS   Belda,E., Sekowska,A., Le Fevre,F., Morgat,A., Mornico,D.,
            Ouzounis,C., Vallenet,D., Medigue,C. and Danchin,A.
  TITLE     An updated metabolic view of the Bacillus subtilis 168 genome
  JOURNAL   Microbiology (Reading, Engl.) 159 (Pt 4), 757-770 (2013)
   PUBMED   23429746
REFERENCE   3  (bases 1 to 2941)
  AUTHORS   Barbe,V., Cruveiller,S., Kunst,F., Lenoble,P., Meurice,G.,
            Sekowska,A., Vallenet,D., Wang,T., Moszer,I., Medigue,C. and
            Danchin,A.
  TITLE     From a consortium sequence to a unified sequence: the Bacillus
            subtilis 168 reference genome a decade later
  JOURNAL   Microbiology (Reading, Engl.) 155 (Pt 6), 1758-1775 (2009)
   PUBMED   19383706
REFERENCE   4  (bases 1 to 2941)
  AUTHORS   Kunst,F., Ogasawara,N., Moszer,I., Albertini,A.M., Alloni,G.,
            Azevedo,V., Bertero,M.G., Bessieres,P., Bolotin,A., Borchert,S.,
            Borriss,R., Boursier,L., Brans,A., Braun,M., Brignell,S.C., Bron,S.,
            Brouillet,S., Bruschi,C.V., Caldwell,B., Capuano,V., Carter,N.M.,
            Choi,S.K., Cordani,J.J., Connerton,I.F., Cummings,N.J., Daniel,R.A.,
            Denziot,F., Devine,K.M., Dusterhoft,A., Ehrlich,S.D., Emmerson,P.T.,
            Entian,K.D., Errington,J., Fabret,C., Ferrari,E., Foulger,D.,
            Fritz,C., Fujita,M., Fujita,Y., Fuma,S., Galizzi,A., Galleron,N.,
            Ghim,S.Y., Glaser,P., Goffeau,A., Golightly,E.J., Grandi,G.,
            Guiseppi,G., Guy,B.J., Haga,K., Haiech,J., Harwood,C.R., Henaut,A.,
            Hilbert,H., Holsappel,S., Hosono,S., Hullo,M.F., Itaya,M., Jones,L.,
            Joris,B., Karamata,D., Kasahara,Y., Klaerr-Blanchard,M., Klein,C.,
            Kobayashi,Y., Koetter,P., Koningstein,G., Krogh,S., Kumano,M.,
            Kurita,K., Lapidus,A., Lardinois,S., Lauber,J., Lazarevic,V.,
            Lee,S.M., Levine,A., Liu,H., Masuda,S., Mauel,C., Medigue,C.,
            Medina,N., Mellado,R.P., Mizuno,M., Moestl,D., Nakai,S., Noback,M.,
            Noone,D., O'Reilly,M., Ogawa,K., Ogiwara,A., Oudega,B., Park,S.H.,
            Parro,V., Pohl,T.M., Portelle,D., Porwollik,S., Prescott,A.M.,
            Presecan,E., Pujic,P., Purnelle,B., Rapoport,G., Rey,M.,
            Reynolds,S., Rieger,M., Rivolta,C., Rocha,E., Roche,B., Rose,M.,
            Sadaie,Y., Sato,T., Scanlan,E., Schleich,S., Schroeter,R.,
            Scoffone,F., Sekiguchi,J., Sekowska,A., Seror,S.J., Serror,P.,
            Shin,B.S., Soldo,B., Sorokin,A., Tacconi,E., Takagi,T.,
            Takahashi,H., Takemaru,K., Takeuchi,M., Tamakoshi,A., Tanaka,T.,
            Terpstra,P., Togoni,A., Tosato,V., Uchiyama,S., Vandebol,M.,
            Vannier,F., Vassarotti,A., Viari,A., Wambutt,R., Wedler,H.,
            Weitzenegger,T., Winters,P., Wipat,A., Yamamoto,H., Yamane,K.,
            Yasumoto,K., Yata,K., Yoshida,K., Yoshikawa,H.F., Zumstein,E.,
            Yoshikawa,H. and Danchin,A.
  TITLE     The complete genome sequence of the gram-positive bacterium Bacillus
            subtilis
  JOURNAL   Nature 390 (6657), 249-256 (1997)
   PUBMED   9384377
REFERENCE   5  (bases 1 to 2941)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-SEP-2018) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   6  (bases 1 to 2941)
  AUTHORS   Genoscope -,C.E.A.
  CONSRTM   AMAbiotics and Genoscope
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2013) A. Danchin, AMAbiotics, Bldg G1, 2, rue
            Gaston Cremieux, 91000 EVRY antoine.danchin@normalesup.org Bldg G1
            Genoscope / CEA (Commissariat a l'energie atomique et aux energies
            alternatives): BP 191 91006 EVRY cedex - FRANCE (E-mail:
            seqref@genoscope.cns.fr - Web: www.genoscope.cns.fr)
REFERENCE   7  (bases 1 to 2941)
  AUTHORS   Genoscope -,C.E.A.
  CONSRTM   Institut Pasteur and Genoscope
  TITLE     Direct Submission
  JOURNAL   Submitted (29-JAN-2009) Genoscope - Centre National de Sequencage :
            BP 191 91006 EVRY cedex - FRANCE (E-mail : seqref@genoscope.cns.fr -
            Web : www.genoscope.cns.fr)
REFERENCE   8  (bases 1 to 2941)
  AUTHORS   Kunst,F., Ogasawara,N., Yoshikawa,H. and Danchin,A.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-NOV-1997) I. Moszer, A. Danchin, Genetique des Genomes
            Bacteriens, Institut Pasteur, 28 rue du Docteur Roux, 75724 Paris
            Cedex 15, FRANCE. E-mail: moszer@pasteur.fr,
            antoine.danchin@normalesup.org Phone: +33 (0)1 45 68 84 41, Fax: +33
            (0)1 45 68 89 48
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to AL009126.
            On Aug 12, 2009 this sequence version replaced NC_000964.2.
            On or before Mar 17, 2009 this sequence version replaced
            gi:32468687, gi:32468690, gi:32468695, gi:32468704, gi:32468715,
            gi:32468723, gi:32468738, gi:32468743, gi:32468745, gi:32468758,
            gi:32468767, gi:32468778, gi:32468787, gi:32468796, gi:32468802,
            gi:32468809, gi:32468813, gi:32468825, gi:32468830, gi:32468833,
            gi:32468840, gi:38680335.
            Annotation results relative to BLAST similarities, COG
            assignations, enzymatic function prediction (PRIAM software), TMHMM
            and SignalP predictions, and synteny conservation (Syntonizer
            software) are available in the MicroScope annotation platform
            http://www.genoscope.cns.fr/agc/microscope.
            The large cluster comprising the i, h and g rDNA regions could not
            be properly resolved, we therefore incorporated the original
            sequence of rRNAihg in the final assembly.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..2941
                     /organism="Bacillus subtilis subsp. subtilis str. 168"
                     /mol_type="genomic DNA"
                     /strain="168"
                     /sub_species="subtilis"
                     /type_material="type strain of Bacillus subtilis"
                     /db_xref="taxon:224308"
     gene            complement(1..1269)
                     /gene="xynC"
                     /locus_tag="BSU_18150"
                     /old_locus_tag="BSU18150"
     CDS             complement(1..1269)
                     /gene="xynC"
                     /locus_tag="BSU_18150"
                     /old_locus_tag="BSU18150"
                     /EC_number="3.2.1.136"
                     /function="16.11: Scavenge (Catabolism)"
                     /experiment="publication(s) with functional evidences,
                     PMID:17028274, 25355936, 26559526, 28330222"
                     /note="Evidence 1a: Function from experimental evidences in
                     the studied strain; PubMedId: 17028274, 25355936, 26559526,
                     28330222; Product type e: enzyme"
                     /codon_start=1
                     /transl_table=11
                     /product="GH30|GH30_8"
                     /protein_id="NP_389697.1"
                     /db_xref="EnsemblGenomes-Gn:BSU18150"
                     /db_xref="EnsemblGenomes-Tr:CAB13698"
                     /db_xref="GOA:Q45070"
                     /db_xref="InterPro:IPR001139"
                     /db_xref="InterPro:IPR017853"
                     /db_xref="InterPro:IPR033452"
                     /db_xref="PDB:3GTN"
                     /db_xref="PDB:3KL0"
                     /db_xref="PDB:3KL3"
                     /db_xref="PDB:3KL5"
                     /db_xref="SubtiList:BG11830"
                     /db_xref="UniProtKB/Swiss-Prot:Q45070"
                     /translation="MIPRIKKTICVLLVCFTMLSVMLGPGATEVLAASDVTVNVSAEKQ
                     VIRGFGGMNHPAWAGDLTAAQRETAFGNGQNQLGFSILRIHVDENRNNWYKEVETAKSA
                     VKHGAIVFASPWNPPSDMVETFNRNGDTSAKRLKYNKYAAYAQHLNDFVTFMKNNGVNL
                     YAISVQNEPDYAHEWTWWTPQEILRFMRENAGSINARVIAPESFQYLKNLSDPILNDPQ
                     ALANMDILGTHLYGTQVSQFPYPLFKQKGAGKDLWMTEVYYPNSDTNSADRWPEALDVS
                     QHIHNAMVEGDFQAYVWWYIRRSYGPMKEDGTISKRGYNMAHFSKFVRPGYVRIDATKN
                     PNANVYVSAYKGDNKVVIVAINKSNTGVNQNFVLQNGSASNVSRWITSSSSNLQPGTNL
                     TVSGNHFWAHLPAQSVTTFVVNR"
     gene            complement(1400..2941)
                     /gene="xynD"
                     /locus_tag="BSU_18160"
                     /old_locus_tag="BSU18160"
     CDS             complement(1400..2941)
                     /gene="xynD"
                     /locus_tag="BSU_18160"
                     /old_locus_tag="BSU18160"
                     /EC_number="3.2.1.55"
                     /function="16.11: Scavenge (Catabolism)"
                     /experiment="publication(s) with functional evidences,
                     PMID:1938968, 17426966, 26559526"
                     /note="Evidence 1a: Function from experimental evidences in
                     the studied strain; PubMedId: 1938968, 17426966, 26559526;
                     Product type e: enzyme"
                     /codon_start=1
                     /transl_table=11
                     /product="GH43_16|CBM6"
                     /protein_id="NP_389698.1"
                     /db_xref="EnsemblGenomes-Gn:BSU18160"
                     /db_xref="EnsemblGenomes-Tr:CAB13699"
                     /db_xref="GOA:Q45071"
                     /db_xref="InterPro:IPR005084"
                     /db_xref="InterPro:IPR006584"
                     /db_xref="InterPro:IPR006710"
                     /db_xref="InterPro:IPR008979"
                     /db_xref="InterPro:IPR023296"
                     /db_xref="PDB:3C7E"
                     /db_xref="PDB:3C7F"
                     /db_xref="PDB:3C7G"
                     /db_xref="PDB:3C7H"
                     /db_xref="PDB:3C7O"
                     /db_xref="SubtiList:BG11807"
                     /db_xref="UniProtKB/Swiss-Prot:Q45071"
                     /translation="MRKKCSVCLWILVLLLSCLSGKSAYAATSTTIAKHIGNSNPLIDH
                     HLGADPVALTYNGRVYIYMSSDDYEYNSNGTIKDNSFANLNRVFVISSADMVNWTDHGA
                     IPVAGANGANGGRGIAKWAGASWAPSIAVKKINGKDKFFLYFANSGGGIGVLTADSPIG
                     PWTDPIGKPLVTPSTPGMSGVVWLFDPAVFVDDDGTGYLYAGGGVPGVSNPTQGQWANP
                     KTARVIKLGPDMTSVVGSASTIDAPFMFEDSGLHKYNGTYYYSYCINFGGTHPADKPPG
                     EIGYMTSSSPMGPFTYRGHFLKNPGAFFGGGGNNHHAVFNFKNEWYVVYHAQTVSSALF
                     GAGKGYRSPHINKLVHNADGSIQEVAANYAGVTQISNLNPYNRVEAETFAWNGRILTEK
                     STAPGGPVNNQHVTSIQNGDWIAVGNADFGAGGARSFKANVASTLGGKIEVRLDSADGK
                     LVGTLNVPSTGGAQTWREIETAVSGATGVHKVFFVFTGTGTGNLFNFDYWQFTQR"
ORIGIN
        1 ttaacgattt acaacaaatg ttgtcacgct ttgagctgga agatgagccc aaaaatgatt
       61 gcctgataca gtgagattcg ttccaggttg tagattgctg ctgctgctcg tgatccatct
      121 agatacgttt gaagcagatc cattctgcaa aacaaagttt tggttgactc ctgtgttgct
      181 tttattgatg gcaacaataa cgaccttgtt gtcaccttta taggctgaca cgtaaacgtt
      241 cgcattaggg tttttcgttg catcaatcct tacatagccg ggacgcacaa actttgagaa
      301 atgagccata ttgtagccgc gtttgctgat cgtaccatct tctttcatag gtccatatga
      361 tcttcggatg taccaccata cataagcttg aaagtccccc tctaccatcg cattgtgaat
      421 atgctgtgaa acatccaatg cctcaggcca tcgatccgcc gagttggtat cactgtttgg
      481 atagtatact tccgtcatcc aaaggtcctt ccccgctcct ttttgtttga aaagaggata
      541 agggaattgg ctgacctggg tgccgtacag gtgagttccg agaatatcca tattggcaag
      601 agcctgcgga tcgttcaaga tcgggtccga caaattcttc aagtattgaa atgactcagg
      661 cgcaatgacg cgggcattga tcgagccggc gttttctctc ataaagcgaa gtatttcttg
      721 cggcgtccac cacgtccact cgtgagcgta atcaggctcg ttttggaccg aaatcgcgta
      781 aagattcaca ccattattct tcatgaaggt aacaaaatcg ttaagatgct gcgcgtatgc
      841 tgcgtacttg ttgtatttca gccgtttagc cgatgtgtca ccattccgat taaaggtctc
      901 aaccatatca cttggaggat tccaaggaga agcaaaaacg attgctccgt gtttgaccgc
      961 actctttgca gtctccacct ctttatacca attatttcga ttttcatcta catgaattct
     1021 taagattgaa aatcctaact ggttctgtcc attgccaaaa gcagtttctc tttgagctgc
     1081 tgtaagatcc ccagcccaag ccggatgatt catccctcca aaaccgcgaa tcacttgttt
     1141 ctctgcagat acattaactg ttacatcact tgctgccaaa acttcagtag cgcctggccc
     1201 taacatgact gacagcatag tgaaacatac taatagtaca caaattgttt tttttatgcg
     1261 tggaatcatt tattcctctc cttcgtcatg tgtcttttac ggtattaaaa aatctgcatg
     1321 gcatatccat aatggcgggc tgttccggtg ctggcccgta cttcacccgc ctcgttttta
     1381 agcggtccca ttacgagtac tatctttgcg taaactgcca gtaatcaaaa ttaaacaagt
     1441 ttcctgtacc tgttccggta aatacaaaga atactttgtg cacaccggtt gccccgctta
     1501 ccgcagtttc tatttccctc cacgtttgcg ctccgcctgt tgaaggcaca ttcagagttc
     1561 caacaagctt accgtctgca ctgtcgaggc gcacttctat tttcccgcct aaagtggatg
     1621 ctacatttgc tttaaatgac ctggcaccgc ccgctccgaa gtctgcattt cctacagcaa
     1681 tccagtctcc attttgaatg cttgttacat gctgattatt tactggcccg ccgggtgctg
     1741 tggacttctc tgtcaaaatg cgtccattcc aagcaaacgt ttcagcttct acccggttat
     1801 atgggtttaa attggaaatt tgtgttacac ctgcataatt tgccgctacc tcttgaatag
     1861 atccatctgc attatgcacc agcttattaa tatggggaga gcggtatcct ttgccggccc
     1921 cgaacagagc ggaactgaca gtttgcgcat ggtacaccac ataccactcg tttttaaaat
     1981 tgaaaacagc atgatggttg tttccgccac ctccgaaaaa tgcacccgga tttttcagga
     2041 agtgccctct atatgtaaag ggacccatgg gacttgaact ggtcatgtag ccgatctcac
     2101 ccgggggttt atcggccggg tgcgtgccgc cgaaattgat gcaataggag taataatatg
     2161 ttccgttata cttgtgcaat cccgaatctt caaacatgaa aggcgcatca attgtagatg
     2221 cacttccaac aacactcgtc atatcaggcc ccaattttat gactctagcc gttttaggat
     2281 tggcccattg tccctgcgtt ggatttgaaa cgccaggaac gcctccgccg gcatacaggt
     2341 aaccggttcc gtcgtcatct acaaatactg ccggatcaaa aagccataca acaccagaca
     2401 ttcctggcgt acttggcgtt acgagcggtt ttccgattgg gtcggtccat ggaccaatcg
     2461 ggctgtctgc ggtgagaacc ccgatacctc cgccgctgtt tgcgaaataa aggaagaatt
     2521 tatccttgcc attaattttt ttaactgcga ttgacggtgc ccatgacgca cctgcccatt
     2581 ttgcaattcc acggcctcca ttagctccat tggcacctgc taccggaatg gctccgtggt
     2641 ctgtccagtt caccatatcc gctgaagata tgacgaatac tctattcaaa ttggcaaatg
     2701 aattatcttt aattgttccg ttgctattat attcatagtc atcacttgac atatagatgt
     2761 agactcttcc gttataggtc agcgcaaccg gatccgctcc caaatgatgg tcgataagcg
     2821 gatttgaatt ccctatatgt tttgcaattg tagtactagt ggcagcatac gcagacttcc
     2881 cagataagca gctcaataat aaaactagaa tccataaaca tacgctacac tttttcctca
     2941 t
//
