LOCUS       NC_011898               8692 bp    DNA     linear   CON 04-FEB-2020
DEFINITION  Ruminiclostridium cellulolyticum H10, complete sequence.
ACCESSION   NC_011898
VERSION     NC_011898.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN00623037
            Assembly: GCF_000022065.1
KEYWORDS    RefSeq.
SOURCE      Ruminiclostridium cellulolyticum H10
  ORGANISM  Ruminiclostridium cellulolyticum H10
            Bacteria; Firmicutes; Clostridia; Clostridiales;
            Hungateiclostridiaceae; Ruminiclostridium.
REFERENCE   1  (bases 1 to 8692)
  AUTHORS   Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Dalin,E.,
            Tice,H., Bruce,D., Goodwin,L., Pitluck,S., Chertkov,O., Saunders,E.,
            Brettin,T., Detter,J.C., Han,C., Larimer,F., Land,M., Hauser,L.,
            Kyrpides,N., Ivanova,N., Zhou,J. and Richardson,P.
  CONSRTM   US DOE Joint Genome Institute
  TITLE     Complete sequence of Clostridium cellulolyticum H10
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8692)
  AUTHORS   Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Dalin,E.,
            Tice,H., Bruce,D., Goodwin,L., Pitluck,S., Chertkov,O., Saunders,E.,
            Brettin,T., Detter,J.C., Han,C., Larimer,F., Land,M., Hauser,L.,
            Kyrpides,N., Ivanova,N., Zhou,J. and Richardson,P.
  CONSRTM   US DOE Joint Genome Institute
  TITLE     Direct Submission
  JOURNAL   Submitted (06-JAN-2009) US DOE Joint Genome Institute, 2800 Mitchell
            Drive B100, Walnut Creek, CA 94598-1698, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/04/2020 07:32:10
            Annotation Pipeline               :: NCBI Prokaryotic Genome
            Annotation Method                 :: Best-placed reference protein
            Annotation Software revision      :: 4.11
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
            Genes (total)                     :: 3,537
            CDSs (total)                      :: 3,447
            Genes (coding)                    :: 3,334
            CDSs (with protein)               :: 3,334
            Genes (RNA)                       :: 90
            rRNAs                             :: 8, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 113
            CDSs (without protein)            :: 113
            Pseudo Genes (ambiguous residues) :: 0 of 113
            Pseudo Genes (frameshifted)       :: 37 of 113
            Pseudo Genes (incomplete)         :: 81 of 113
            Pseudo Genes (internal stop)      :: 17 of 113
            Pseudo Genes (multiple problems)  :: 20 of 113
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence was derived from
            CP001348.
            URL -- http://www.jgi.doe.gov
            JGI Project ID: 4002584
            Source DNA and bacteria available from Jizhong Zhou
            (jzhou@rccc.ou.edu)
            Contacts: Jizhong Zhou (jzhou@rccc.ou.edu)
            David Bruce (microbe@cuba.jgi-psf.org)
            Annotation done by JGI-ORNL and JGI-PGF
            Finishing done by JGI-LANL
            Finished microbial genomes have been curated to close all gaps with
            greater than 98% coverage of at least two independent clones. Each
            base pair has a minimum q (quality) value of 30 and the total error
            rate is less than one per 50000.
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. it is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376).
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Annotation Pipeline (PGAP)
            set; GeneMarkS-2+
            repeat_region
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..8692
                     /organism="Ruminiclostridium cellulolyticum H10"
                     /mol_type="genomic DNA"
                     /strain="H10"
                     /culture_collection="ATCC:35319"
                     /type_material="type strain of Ruminiclostridium
                     cellulolyticum"
                     /db_xref="taxon:394503"
     gene            1..2169
                     /locus_tag="CCEL_RS03700"
                     /old_locus_tag="Ccel_0729"
     CDS             1..2169
                     /locus_tag="CCEL_RS03700"
                     /old_locus_tag="Ccel_0729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015924275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH48"
                     /protein_id="WP_015924275.1"
                     /translation="MSKNFKRVGAVAVAAAMSLSIMATTSINAASSPANKVYQDRFESM
                     YSKIKDPANGYFSEQGIPYHSIETLMVEAPDYGHVTTSEAMSYYMWLEAMHGRFSGDFT
                     GFDKSWSVTEQYLIPTEKDQPNTSMSRYDANKPATYAPEFQDPSKYPSPLDTSQPVGRD
                     PINSQLTSAYGTSMLYGMHWILDVDNWYGFGARADGTSKPSYINTFQRGEQESTWETIP
                     QPCWDEHKFGGQYGFLDLFTKDTGTPAKQFKYTNAPDADARAVQATYWADQWAKEQGKS
                     VSTSVGKATKMGDYLRYSFFDKYFRKIGQPSQAGTGYDAAHYLLSWYYAWGGGIDSTWS
                     WIIGSSHNHFGYQNPFAAWVLSTDANFKPKSSNGASDWAKSLDRQLEFYQWLQSAEGAI
                     AGGATNSWNGRYEAVPSGTSTFYGMGYVENPVYADPGSNTWFGMQVWSMQRVAELYYKT
                     GDARAKKLLDKWAKWINGEIKFNADGTFQIPSTIDWEGQPDTWNPTQGYTGNANLHVKV
                     VNYGTDLGCASSLANTLTYYAAKSGDETSRQNAQKLLDAMWNNYSDSKGISTVEQRGDY
                     HRFLDQEVFVPAGWTGKMPNGDVIKSGVKFIDIRSKYKQDPEWQTMVAALQAGQVPTQR
                     LHRFWAQSEFAVANGVYAILFPDQGPEKLLGDVNGDETVDAIDLAILKKYLLNSSTTIN
                     TANADMNSDNAIDAIDYALLKKALLSIQ"
     gene            2298..3680
                     /locus_tag="CCEL_RS03705"
                     /old_locus_tag="Ccel_0730"
     CDS             2298..3680
                     /locus_tag="CCEL_RS03705"
                     /old_locus_tag="Ccel_0730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020814341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH8"
                     /protein_id="WP_015924276.1"
                     /translation="MIKGSSLKRFKSLVMAAIFSVSIISTAIASSAADQIPFPYDAKYP
                     NGAYSCLADSQSIGNNLVRSEWEQWKSAHITSNGARGYKRVQRDASTNYDTVSEGLGYG
                     LLLSVYFGEQQLFDDLYRYVKVFLNSNGLMSWRIDSSGNIMGKDSIGAATDADEDIAVS
                     LVFAHKKWGTSGGFNYQTEAKNYINNIYNKMVEPGTYVIKAGDTWGGSNVTNPSYFAPA
                     WYRIFADFTGNSGWINVANKCYEIADKARNSNTGLVPDWCTANGTPASGQGFDFYYDAI
                     RYQWRAAIDYSWYGTAKAKTHCDAISNFFKNIGYANIKDGYTISGSQISSNHTATFVSC
                     AAAAAMTGTDTTYAKNIYNECVKVKDSGNYTYFGNTLRMMVLLYTTGNFPNLYTYNSQP
                     KPDLKGDVNNDGAIDALDIAALKKAILTQTTSNISLTNADMNNDGNIDAIDFAQLKVKL
                     LN"
     gene            3765..5942
                     /locus_tag="CCEL_RS03710"
                     /old_locus_tag="Ccel_0731"
     CDS             3765..5942
                     /locus_tag="CCEL_RS03710"
                     /old_locus_tag="Ccel_0731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014313404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBM3|GH9"
                     /protein_id="WP_015924277.1"
                     /translation="MLKTKRKLTKAIGVALSISILSSLVSFIPQTNTYAAGTYNYGEAL
                     QKSIMFYEFQRSGDLPADKRDNWRDDSGMKDGSDVGVDLTGGWYDAGDHVKFNLPMSYT
                     SAMLAWSLYEDKDAYDKSGQTKYIMDGIKWANDYFIKCNPTPGVYYYQVGDGGKDHSWW
                     GPAEVMQMERPSFKVDASKPGSAVCASTAASLASAAVVFKSSDPTYAEKCISHAKNLFD
                     MADKAKSDAGYTAASGYYSSSSFYDDLSWAAVWLYLATNDSTYLDKAESYVPNWGKEQQ
                     TDIIAYKWGQCWDDVHYGAELLLAKLTNKQLYKDSIEMNLDFWTTGVNGTRVSYTPKGL
                     AWLFQWGSLRHATTQAFLAGVYAEWEGCTPSKVSVYKDFLKSQIDYALGSTGRSFVVGY
                     GVNPPQHPHHRTAHGSWTDQMTSPTYHRHTIYGALVGGPDNADGYTDEINNYVNNEIAC
                     DYNAGFTGALAKMYKHSGGDPIPNFKAIEKITNDEVIIKAGLNSTGPNYTEIKAVVYNQ
                     TGWPARVTDKISFKYFMDLSEIVAAGIDPLSLVTSSNYSEGKNTKVSGVLPWDVSNNVY
                     YVNVDLTGENIYPGGQSACRREVQFRIAAPQGTTYWNPKNDFSYDGLPTTSTVNTVTNI
                     PVYDNGVKVFGNEPAGGSENPDPEILYGDVNSDKNVDALDFAALKKYLLGGTSSIDVKA
                     ADTYKDGNIDAIDMATLKKYLLGTITQLPQG"
     gene            6035..8692
                     /locus_tag="CCEL_RS03715"
                     /old_locus_tag="Ccel_0732"
     CDS             6035..8692
                     /locus_tag="CCEL_RS03715"
                     /old_locus_tag="Ccel_0732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015924278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBM4|GH9"
                     /protein_id="WP_015924278.1"
                     /translation="MKKRLVKKVAMLIAIVLVLSSSIGQAFALVGAGDLIRNHTFDNRV
                     GLPWHVVESYPAKASFEITSDGKYKITAQKIGEAGKGERWDIQFRHRGLALQQGHTYTV
                     KFTVTASRACKIYPKIGDQGDPYDEYWNMNQQWNFLELQANTPKTVTQTFTQTKGDKKN
                     VEFAFHLAPDKTTSEAQNPASFQPITYTFDEIYIQDPQFAGYTEDPPEPTNVVRLNQVG
                     FYPNADKIATVATSSTTPINWQLVNSTGAAVLTGKSTVKGADRASGDNVHIIDFSSYTT
                     PGTDYKIVTDVSVTKAGDNESMKFNIGDDLFTQMKYDSMKYFYHNRSAIPIQMPYCDQS
                     QWARPAGHTTDILAPDPTKDYKANYTLDVTGGWYDAGDHGKYVVNGGIATWTVMNAYER
                     ALHMGGDTSVAPFKDGSLNIPESGNGYPDILDEARYNMKTLLNMQVPAGNELAGMAHHK
                     AHDERWTALAVRPDQDTMKRWLQPPSTAATLNLAAIAAQSSRLWKQFDSAFATKCLTAA
                     ETAWDAAVAHPEIYATMEQGAGGGAYGDNYVLDDFYWAACELYATTGSDKYLNYIKSSK
                     HYLEMPTELTGGENTGITGAFDWGCTAGMGTITLALVPTKLPAADVATAKANIQAAADK
                     FISISKAQGYGVPLEEKVISSPFDASVVKGFQWGSNSFVINEAIVMSYAYEFSDVNGTK
                     NNKYINGALTAMDYLLGRNPNIQSYITGYGDNPLENPHHRFWAYQADNTFPKPPPGCLS
                     GGPNSGLQDPWVKGSGWQPGERPAEKCFMDNIESWSTNEITINWNAPLVWISAYLDEKG
                     PEIGGSVTPPTNLGDVNGDGNKDALDFAALKKALLSQDTSTINVANADINKDGSIDAVD
                     FALLKSFLLGKITL"
ORIGIN
        1 atgagtaaga attttaaaag agtaggagca gttgcagttg ctgctgcaat gtcattatct
       61 ataatggcaa caaccagcat aaatgcagct tcaagtcctg caaacaaggt gtaccaggat
      121 cgttttgaat ccatgtacag caagattaag gatcctgcaa acggatactt cagtgaacag
      181 ggaattcctt accactcaat tgaaacactg atggtcgaag ctcctgacta cggacatgtt
      241 acaacaagtg aagctatgtc ctattatatg tggttggaag caatgcacgg aagattttca
      301 ggagatttta caggttttga taagtcttgg tctgttaccg aacagtattt gatcccaaca
      361 gaaaaggatc agcccaatac aagtatgagc agatatgatg ctaacaaacc ggctacatac
      421 gctccggaat ttcaggaccc aagcaagtat ccttctccgt tggatactag tcaacctgtt
      481 ggtagagatc caatcaactc acaattgact tcagcatacg gaacaagcat gctgtatgga
      541 atgcactgga tacttgacgt tgataactgg tatggatttg gagcaagagc tgatggaacc
      601 tccaagccat catatatcaa tactttccaa agaggtgagc aggagtcaac ttgggaaacc
      661 atacctcaac catgttggga tgaacataaa tttggtggac agtacggatt cctggatctc
      721 tttacaaagg atacaggtac tccggcaaag caattcaaat atacaaatgc tccagatgct
      781 gatgctcgtg cagttcaagc aacttactgg gctgatcagt gggcaaaaga acaaggtaag
      841 agcgtaagta ctagcgtagg taaggcaaca aagatgggtg attaccttag atattcattc
      901 tttgataagt atttcagaaa gatcggacaa ccttctcagg ctggtaccgg atatgatgca
      961 gcacattatc tgctttcatg gtactatgca tggggtggtg gaattgactc tacctggtct
     1021 tggataatcg gtagcagtca taatcatttc ggttaccaga acccatttgc agcttgggta
     1081 ctttcaacag atgcaaactt caagcctaag tcatcaaatg gtgcatcaga ctgggcaaag
     1141 agtttggaca gacagcttga attctatcag tggttgcagt cagcagaagg tgctattgcc
     1201 ggtggagcta caaactcatg gaacggacgt tatgaagcag ttccttcagg tacatcaaca
     1261 ttctatggaa tgggttatgt agaaaaccct gtatatgctg acccaggtag taacacttgg
     1321 tttggtatgc aggtatggtc aatgcagcgt gtagctgaat tgtactataa gactggcgat
     1381 gccagagcta agaaactctt agacaaatgg gcaaaatgga ttaatggcga aatcaagttc
     1441 aatgctgacg gaacattcca gattcctagc acaattgatt gggaaggaca gccggatact
     1501 tggaatccaa cacagggata caccggaaat gcaaacttgc atgttaaagt tgttaactat
     1561 ggtactgacc taggttgtgc ttcttcactt gcaaacacat tgacttacta tgctgctaaa
     1621 tcaggagatg aaacttcaag gcagaatgca cagaaattac ttgacgctat gtggaataac
     1681 tatagcgatt caaagggtat atcaactgtt gaacagcgtg gtgattacca tagattcctt
     1741 gatcaggaag tttttgtacc agctggttgg actggaaaaa tgcctaacgg cgacgtaatc
     1801 aaatctggtg tcaagttcat agacattcgt tccaagtaca agcaggatcc tgaatggcag
     1861 acaatggttg ctgcattaca ggcaggacag gttccaactc agagattaca ccgtttctgg
     1921 gctcagagtg aatttgcagt tgcaaatgga gtttatgcaa tactcttccc agatcaaggt
     1981 ccagaaaaat tattgggtga tgtaaacggt gacgaaactg tagacgctat tgaccttgct
     2041 atacttaaaa aatatctttt aaacagcagt actacaataa atactgcaaa tgcagatatg
     2101 aatagtgata atgctattga cgctattgac tatgctcttt taaagaaagc acttctttct
     2161 atccaatagt atttaatact atgacgcata tgtaacctta aagtccggac agtatttggt
     2221 ttgattaaat tactcattct tgtactgtcc gggcttatga gttacaaaga aaaaaagaaa
     2281 aggattaagg taagaacatg atcaaaggtt caagcttaaa gagatttaaa tcgcttgtta
     2341 tggcggctat atttagtgtt tcaataatct caactgccat cgcttcaagt gcagctgatc
     2401 aaattccttt cccatatgac gcaaaatatc caaatggagc ttacagttgt ctggcggata
     2461 gtcagtcaat cggaaataat ttagttcgca gtgaatggga acagtggaaa agtgcacata
     2521 ttacatcaaa tggagcaaga ggctataaaa gagtccagag agacgcttct acaaactatg
     2581 atacggtttc tgaaggactt ggatacggtt tgctgctttc agtttacttt ggagaacaac
     2641 aattatttga cgatttatat cgctatgtta aagtattttt aaattcgaac ggacttatgt
     2701 cctggcgtat tgactccagc ggaaatataa tgggaaaaga cagtattggt gccgcaacag
     2761 atgcagatga agatattgcg gtatcccttg tgtttgctca taaaaaatgg ggaacaagtg
     2821 gaggatttaa ttaccagact gaggctaaaa attacataaa taacatatac aataaaatgg
     2881 tagaaccggg tacatatgta ataaaagcag gagatacgtg gggagggtca aatgtaacta
     2941 atccgtcata ttttgcccca gcttggtaca gaatctttgc tgactttaca ggtaattccg
     3001 gatggatcaa tgtagcaaat aaatgttatg aaatagctga taaagcaaga aacagtaata
     3061 caggacttgt tcctgattgg tgtacagcaa atggtactcc ggcatcagga caaggttttg
     3121 atttctatta tgatgcaatt cgttaccagt ggagagcagc tattgattac agttggtatg
     3181 gcactgcaaa agctaaaaca cattgcgatg ctatctcaaa cttcttcaag aatattgggt
     3241 atgctaatat aaaagatggc tacacaatat caggaagtca gataagttca aatcataccg
     3301 ctacttttgt cagctgtgct gctgctgctg caatgacggg tactgacact acatatgcaa
     3361 agaacattta taacgagtgt gttaaagtaa aagattcagg taactacacc tatttcggca
     3421 atactttaag aatgatggtt cttctatata ctacgggtaa cttcccaaat ctatacacct
     3481 acaactctca accaaaaccg gatttaaaag gcgatgtcaa taatgatggt gctatagatg
     3541 cacttgatat tgctgcactc aagaaggcta ttttaactca aacaacttct aatataagtt
     3601 taacaaatgc tgatatgaat aatgacggta atatagatgc cattgatttt gctcagctaa
     3661 aagttaaact gcttaactag aataaataaa aataattgag tgagcatctc aggttaaatt
     3721 tgtcttaaaa atgtttaaat ttaattttag ggagtgatgg caagttgctt aagactaaaa
     3781 gaaaattgac aaaagcaatc ggtgttgcat tatcgatttc aatattatct tcgctagtat
     3841 cgtttatacc tcaaacaaat acatatgcag caggaacata taactatgga gaagcattac
     3901 agaaatcaat aatgttctat gaattccagc gttcgggaga tcttccggct gataaacgtg
     3961 acaactggag agacgattcc ggtatgaaag acggttctga tgtaggagtt gatcttacag
     4021 gaggatggta cgatgcaggt gaccatgtga aatttaatct acctatgtca tatacatctg
     4081 caatgcttgc atggtcctta tatgaggata aggatgctta tgataagagc ggtcagacaa
     4141 aatatataat ggacggtata aaatgggcta atgattattt tattaaatgt aatccgacac
     4201 ccggtgtata ttattaccaa gtaggagacg gcggaaagga ccactcttgg tggggccctg
     4261 cggaagtaat gcagatggaa agaccgtctt ttaaggttga cgcttctaag cccggttctg
     4321 cagtatgtgc ttccactgca gcttctctgg catctgcagc agtagtcttt aaatccagtg
     4381 atcctactta tgcagaaaag tgcataagcc atgcaaagaa cctgtttgat atggctgaca
     4441 aagcaaagag tgatgctggt tatactgcgg cttcaggcta ctacagctca agctcatttt
     4501 acgatgatct ctcatgggct gcagtatggt tatatcttgc tacaaatgac agtacatatt
     4561 tagacaaagc agaatcctat gtaccgaatt ggggtaaaga acagcagaca gatattatcg
     4621 cctacaagtg gggacagtgc tgggatgatg ttcattatgg tgctgagctt cttcttgcaa
     4681 agcttacaaa caaacaattg tataaggata gtatagaaat gaaccttgac ttctggacaa
     4741 ctggtgttaa cggaacacgt gtttcttaca cgccaaaggg tttggcgtgg ctattccaat
     4801 ggggttcatt aagacatgct acaactcagg cttttttagc cggtgtttat gcagagtggg
     4861 aaggctgtac gccatccaaa gtatctgtat ataaggattt cctcaagagt caaattgatt
     4921 atgcacttgg cagtaccgga agaagttttg ttgtcggata tggagtaaat cctcctcaac
     4981 atcctcatca cagaactgct cacggttcat ggacagatca aatgacttca ccaacatacc
     5041 acaggcatac tatttatggt gcgttggtag gaggaccgga taatgcagat ggctatactg
     5101 atgaaataaa caattatgtc aataatgaaa tagcctgcga ttataatgcc ggatttacag
     5161 gtgcacttgc aaaaatgtac aagcattctg gcggagatcc gattccaaac ttcaaggcta
     5221 tcgaaaaaat aaccaacgat gaagttatta taaaggcagg tttgaattca actggcccta
     5281 actacactga aatcaaggct gttgtttata accagacagg atggcctgca agagttacgg
     5341 acaagatatc atttaaatat tttatggact tgtctgaaat tgtagcagca ggaattgatc
     5401 ctttaagcct tgtaacaagt tcaaattatt ctgaaggtaa gaatactaag gtttccggtg
     5461 tgttgccatg ggatgtttca aataatgttt actatgtaaa tgttgatttg acaggagaaa
     5521 atatctaccc aggcggtcag tctgcgtgca gacgagaagt tcagttcaga attgccgcac
     5581 cacagggaac aacatattgg aatccgaaaa atgatttctc atatgatgga ttaccaacca
     5641 ccagtactgt aaatacggtt accaacatac ctgtttatga taacggcgta aaagtatttg
     5701 gtaacgaacc cgcaggtgga tcggaaaacc ctgatcctga aatcttgtat ggagacgtaa
     5761 acagcgacaa aaatgtagat gcattggact ttgctgcatt gaagaaatat ttacttggag
     5821 gcacttccag catagatgtt aaggctgcag atacatacaa ggatgggaat attgacgcta
     5881 tagatatggc taccttgaag aagtatttat tgggaacaat cacccaatta cctcaaggct
     5941 aatagaagtt cagtttggaa gtttaatgag tttttaatgc ttgcattact aaatgtaagc
     6001 tttaaaaaat aaaaaatttt actaggaggt aaatatgaaa aaaaggttag tgaagaaagt
     6061 tgcgatgctc atcgcaatag tgctggttct atcttcttca ataggacaag catttgccct
     6121 tgttggggca ggagatttga ttcgaaacca tacctttgac aacagagtag gtcttccatg
     6181 gcacgtggtt gaatcatacc ctgcaaaggc aagttttgaa attacatctg atggtaagta
     6241 caagataact gctcaaaaga tcggtgaggc aggaaaaggt gaaagatggg atatacaatt
     6301 ccgtcacaga ggactcgcat tgcaacaagg tcatacttat acagtaaagt ttactgttac
     6361 tgctagcaga gcttgtaaaa tttatcctaa aataggtgac cagggtgatc catatgatga
     6421 atactggaat atgaatcaac aatggaattt cctggaatta caggctaata ctccaaaaac
     6481 tgtaactcag acatttacac agactaaggg agataagaag aacgttgaat ttgcttttca
     6541 ccttgctccc gataaaacta catctgaggc acagaatcca gcaagtttcc aacctataac
     6601 atatactttt gatgaaattt atattcagga ccctcaattt gcaggatata ctgaagatcc
     6661 acctgaacct actaatgttg tacgtttgaa tcaggtaggt ttctatccta atgctgataa
     6721 gattgcaaca gtagcaacaa gttcaacaac tccaattaac tggcagttgg ttaatagtac
     6781 tggagcagct gttttaacag gtaaatcaac tgttaaaggt gccgaccgtg catcaggtga
     6841 taatgtccat atcattgatt tctctagtta cacaacacct ggtaccgact ataagatagt
     6901 aacagatgta tcagtaacaa aagccggaga caatgaaagt atgaagttca atattggaga
     6961 tgaccttttt actcaaatga aatacgattc aatgaagtat ttctatcaca acagaagtgc
     7021 tattccaata caaatgccat actgtgatca atcacaatgg gcacgtcctg caggacacac
     7081 aactgatata cttgctccag atccaacaaa ggattacaag gctaactaca cacttgacgt
     7141 tacaggtggt tggtatgatg ccggtgacca tggtaagtat gttgttaatg gtggtattgc
     7201 aacctggacc gtaatgaatg catatgagcg tgcactacac atgggtggag acacttcagt
     7261 tgctccattt aaagacggtt cattgaacat acctgaaagc ggaaatggct atcctgacat
     7321 actggacgaa gctcgttaca atatgaaaac attattaaat atgcaggttc cagcaggaaa
     7381 tgaattagcc ggtatggctc accacaaagc tcatgacgaa cgttggacag ctcttgctgt
     7441 acgtcccgac caggatacaa tgaaacgttg gttgcagcct ccaagtacag cagctacatt
     7501 aaatctggct gctattgctg cacaaagttc acgtctttgg aaacagtttg attctgcttt
     7561 cgcaactaag tgtttaactg cagcagaaac tgcatgggat gcagctgtag ctcatccaga
     7621 aatatatgca actatggaac agggtgccgg tggtggagca tacggagaca actatgttct
     7681 tgatgatttc tactgggcag catgtgaatt gtatgcaact acaggcagtg acaagtattt
     7741 gaactacata aagagctcaa agcattatct cgaaatgcct acagaattaa caggcggtga
     7801 gaatactgga attacagggg cttttgactg gggttgtaca gcaggtatgg gaacaataac
     7861 acttgcactt gtacctacaa agcttccggc agcagatgtt gctacagcta aagctaatat
     7921 tcaagctgca gctgataagt tcatatcaat ttcaaaagca caaggctatg gtgtaccact
     7981 agaagaaaaa gtaatttcat ctccttttga tgcatctgtt gttaaaggtt tccaatgggg
     8041 atcaaactca ttcgttatta atgaagcaat agttatgtca tatgcttatg aattcagcga
     8101 tgttaatggc acaaagaata ataaatatat taatggtgct ttaacagcaa tggattacct
     8161 cctcggacgt aacccaaata ttcaaagcta tataactggt tatggtgaca acccacttga
     8221 aaatcctcat caccgtttct gggcatacca ggcagacaac acattcccaa aaccacctcc
     8281 gggatgtctg tcaggaggac ctaactccgg cttgcaggat ccttgggtta agggttcagg
     8341 ctggcagcca ggtgaaagac ctgctgaaaa atgcttcatg gacaatattg aatcttggtc
     8401 aacaaacgaa ataaccatca actggaatgc tcctcttgta tggatatcag cttaccttga
     8461 tgaaaagggg ccagagattg gtgggtcagt gactcctcca actaatttag gagatgttaa
     8521 cggcgatgga aacaaggatg cattggactt cgctgcattg aagaaagcct tgttaagcca
     8581 ggatacttct actataaatg ttgctaatgc tgatataaac aaagatggtt ctattgatgc
     8641 agttgacttt gcattactca aatcattctt gttaggaaaa atcacactgt aa
//
