LOCUS       AB812036               20537 bp    DNA     linear   BCT 13-MAY-2015
DEFINITION  Escherichia coli genes for O-antigen biosynthetic locus, partial
            sequence, strain: H19.
ACCESSION   AB812036
VERSION     AB812036.1
KEYWORDS    .
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1
  AUTHORS   Iguchi,A., Iyoda,S., Kikuchi,T., Ogura,Y., Katsura,K., Ohnishi,M.,
            Hayashi,T. and Thomson,N.R.
  TITLE     A complete view of the genetic diversity of the Escherichia coli
            O-antigen biosynthesis gene cluster
  JOURNAL   DNA Res. 22 (1), 101-107 (2015)
   PUBMED   25428893
  REMARK    DOI:10.1093/dnares/dsu043
REFERENCE   2  (bases 1 to 20537)
  AUTHORS   Iguchi,A., Iyoda,S. and Ohnishi,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-APR-2013) Contact:Atsushi Iguchi University of
            Miyazaki, Faculty of Agriculture; Gakuen-kibanadai-nishi 1-1,
            Miyazaki, Miyazaki 889-2192, Japan
FEATURES             Location/Qualifiers
     source          1..20537
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="H19"
                     /db_xref="taxon:562"
                     /note="serogroup:O84"
     gene            <1..898
                     /gene="wcaM"
     CDS             <1..898
                     /gene="wcaM"
                     /codon_start=2
                     /transl_table=11
                     /product="colanic acid biosynthesis protein"
                     /protein_id="BAQ01287.1"
                     /translation="ILRQGFHNQIIGANITNCKFSDLQGDAIEWNVAINDRDILISDHV
                     IERINCTNGKINWGIGIGLAGSTYDNNYPEDQAVKNFVVANITGSDCRQLIHVENGKHF
                     VIRNIKARNITPDFSKKAGIDNATVAIYGCDNFVIDNIEMINSAGMLIGYGVIKGKYLS
                     IPQNFRVNNTQLDNTHLAYKLRGIQISAGNALSFVALTNIEMKRASLELHNKPQHLFMR
                     NIKVMQESSVGPALSMNFDMRKDVRGVFMAKKETLLSLANVHAVNEKGQSSVDIDRVNH
                     HIVNVEKINFRLPERRE"
     gene            1062..1967
                     /gene="galF"
     CDS             1062..1967
                     /gene="galF"
                     /note="O084_01"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP-glucose-1-phosphate uridylyltransferase"
                     /protein_id="BAQ01288.1"
                     /translation="MDEIMTNLKAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMIQYIV
                     DEIVAAGIKEILLVTHASKNAVENHFDTSYELESLLEQRVKRQLLAEVQSICPPGVTIM
                     NVRQGEPLGLGHSILCARPAIGDNPFVVVLPDVVIDDASADPLRYNLAAMIARFNETGR
                     SQVLAKRMPGDLSEYSVIQTKEPLDREGKVSRIVEFIEKPDQPQTLDSDIMAVGRYVLS
                     ADIWPELEHTQPGAWGRIQLTDAIAELAKKQSVDAMLMTGDSYDCGKKMGYMQAFVKYG
                     LRNLKEGAKFRKGIEKLLSE"
     gene            2379..3773
                     /gene="wzx"
     CDS             2379..3773
                     /gene="wzx"
                     /note="O084_02"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen flippase"
                     /protein_id="BAQ01289.1"
                     /translation="MLSKIKNVIDRIVIIFKPIAADLTQKEKDEVIRLRGVYLTAIISL
                     LSKIISMISIFITIPAILNYLGEELFGIWMTLSSIIAMLTFADMGIGNGVVNKLSKAIY
                     SNSVNDIRKIITNAVTVLLIIATSINLLFYAATPLVSWNRILNLSEKIDSHSIEHALFV
                     FVFCFSLNVLFSIVQKIQLAYQLGFIASIWQILGSVFSLGLLFLFINLKLEMAWLVFSI
                     AGIPAIFQLLNYLHFSLVICKTGFFKISFIKIAEMKSLLSTGVLFFALQISMVCTYTSD
                     NIILNTIIGAEAVTEYSVHVRLFSVIPILMGMVLIPLWPAYSSARIKKDIKWIRDVWNK
                     SIMMALLVSVFIGGSIILFLPDIFDLWLKNKIQPTYTLAYMLFVWKLFESVGLAISCFL
                     NGMDLIKQQAFIAVVTAVVAISLKILFVYQIGITGVLLGTLIPFVLLTFIPTLFISLGF
                     LRKGMC"
     CDS             3767..4384
                     /note="O084_03"
                     /codon_start=1
                     /transl_table=11
                     /product="putative acetyltransferase"
                     /protein_id="BAQ01290.1"
                     /translation="MLMKKFISRLLYNPYKKIKKDSRIEFNSGILDKNFRVHFYCSESR
                     AKAYIGNNCILKNEIIFERECGVVTIGDNTFINKNTKIISVNRISIGSNVTISYGVIIY
                     DHDSHSLDYRERQKDILKILETRDPNNDIENKNWDCVKSLPVIIGDNVWIGFQAAILKG
                     VTIGEGAVVAARAVVTKDVPAWSVVAGNPAKVVKEIPRDMRK"
     CDS             4386..5306
                     /note="O084_04"
                     /codon_start=1
                     /transl_table=11
                     /product="putative nucleotide sugar epimerase"
                     /protein_id="BAQ01291.1"
                     /translation="MKNITIMILGAGGFIGSHLCNSCIQNGATVYALGRNLDNVKIKNQ
                     RFIKLSSNEITEKTLFDVAQPDYVYFLMGAASVAKSIEAPLYDFNQSLPPLLVILEKLR
                     KEWIGTRLIFISSAAVYGENASERTSVSSLPMPLSPYGLNKKISETYVQYYMKHYDISA
                     KIIRPFSVYGPGLKKQLIWDVLNKIKDKQHHYFGSGNEMRDWIYIDDFIAVLFNYVSNY
                     ALMSDLINVGTGIPIKVKNVIEQLYTLTDTFEIPSFSDGGKEGDPKHLVSNYEEQDFLR
                     ELLKTPLELGLRNTVDWFKNQEEQC"
     CDS             5300..6439
                     /note="O084_05"
                     /codon_start=1
                     /transl_table=11
                     /product="putative glycosyltransferase"
                     /protein_id="BAQ01292.1"
                     /translation="MLKVGIPVLFSEQHWMGGINYFRSLISAFSLVEQNDIELIIFCEK
                     DGLFNTTKLNNVRQVIIPELLPRKLSKRIINKVYGVNFELYKAIKNESVDILSHTQINK
                     RLACKTMWWKPDFQEKYYPEFFNEKDLFLRNQSVVNNALRGYLLFSSNDAKNDFFKFYN
                     TLPTQNINVLQFVPEIEISSSQDENDRIIAVKEKYGISGDYFFLPNQFWKHKNHELVIK
                     AIITGDIPAKVVATGASNDYRGGRHIELINQLLKQDSAKKFKLLGLVDRDDVNLLMKGA
                     IAVINPSRFEGWSTTVEEAKYLGKRLILSDIPVHHEQNPPDSLYVSCDDVSGMISAMRK
                     IIDEYDTEKEIFRAKKAAEQYKFKRKEFGLSYYNILKSL"
     gene            6441..7592
                     /gene="wzy"
     CDS             6441..7592
                     /gene="wzy"
                     /note="O084_06"
                     /codon_start=1
                     /transl_table=11
                     /product="GT4"
                     /protein_id="BAQ01293.1"
                     /translation="MAIYIFISISCLISYVLSNNDKNSLSPRFLLIILTLFTGLSYTNG
                     WDWYGYLDFYNNIQNEGVSAIYEYNIYGIEYLYLIYLYIVGLSGGSFSLFILLNAIIIN
                     FLIYSFCKRAYVNYSLFMFIFIAASYLRLELSTIRQGLAVVIVIYSYSLLLNSKINLSL
                     LFIFLAICFHRSAAIVLLFFPFVYYNSARNIHYFIVILTIPFVILSGELNVVFIKILNA
                     FNSSLLNAYISKLIIYLSLNKQAIINPQAMALLVFYFICIRVCDVKNKKQIIFLNIIAC
                     QVIISFYFIFLTQLIIMRLVYYFQVGWICWVIILYKEYFRPKWLCFFLICLLFITKSIL
                     NFRYEQDRAVFFPYYNVISSYLDDNYGRSRSFILNKADELFKE"
     CDS             7573..8715
                     /note="O084_07"
                     /codon_start=1
                     /transl_table=11
                     /product="putative glycerophosphotransferase"
                     /protein_id="BAQ01294.1"
                     /translation="MSFLRSKMSKKIKYIINFAMSLFILPFFYIEKKIIGKKIWLCGAG
                     NGYYENNIASIHDYILKSLPLAKNKIFFVTTNRELLSGDVAFPVLIRGHLKTYALSILA
                     DYLIFDTCNSDIAPGIHRYLSALKVNVNHGFEGLKKLPEDYYAKIDADIHCASSMREKY
                     IKVFECGAANEKVFITGYPRFDRIVSRENSHVKKILFFPTWRSWLESLSNDELNNSTYV
                     RSIYDFLYSERLKEYLSENNIIMYYKPHHKISHLKLDLSSCKNIILLKDYDDLTHYICE
                     SDLLITDYSSVAWDFLYSNREVIFYIFDIDEYILKQGLYYDVRTSLRNYGGTPDEIINL
                     LKKERKEVDLNLSSMAGEFFEYRDNKNSERILKLICEYKI"
     CDS             8712..9983
                     /note="O084_08"
                     /codon_start=1
                     /transl_table=11
                     /product="putative glycosyltransferase"
                     /protein_id="BAQ01295.1"
                     /translation="MKVKIISYSLSKGGAAKAAKNFLHLASKNKKYEAEMISVSGIIKN
                     GVLFKSSKLSVFWHYSKMLVSRVLTYFILNDKSIKYSLNIFDSNYVLKHIRVEDGQREV
                     IHINWVNNDTLSLFSLSKLFENKRKRIILTLHDEWFYCASEHYAKYNSLCYVTGYDDSN
                     FINSYIFELKKRINFENVVITVPSYWLYERAKKSYLLSNCDIYILPNYIDTNIFTELKD
                     IRSKRYRILDVPEDAFIIGFGAVSGGANPLKGFDLLVSALDEVLSKINDKARIVMVTFG
                     ANDIDKRVTSLGCHIINMGVISNSHNMAEIYNYLDVMIVPSRVESFGQVAAESLACKTP
                     VIAFDYSGIKDIVTHQRSGLLAEPFSVDSLALNINSFMNMTEKERYVYGENGRDDVVRK
                     FGETVVSEIYFKLIDYVRGDEYEK"
     gene            9973..11097
                     /gene="gmd"
     CDS             9973..11097
                     /gene="gmd"
                     /note="O084_09"
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
                     /protein_id="BAQ01296.1"
                     /translation="MKNKVALITGVTGQDGSYLAEFLLEKGYEVHGIKRRASSFNTERV
                     DHIYQDRHNENPDFILHYGDLTDSSNLIRLIKEIQPDEVYNLGAQSHVAVSFESPEYTA
                     DVDAMGTLRLLEAIRICGLEKKTRFYQASTSELFGLVQEIPQRETTPFYPRSPYAVAKM
                     YAYWITINYRESYGMYACNGILFNHESPRRGETFVTRKITRAIANVSQGIEKCLYLGNM
                     DSLRDWGHAKDYVRMQWMMLQQERPEDFVIATGKQISVREFVRMAAKEVGLELQFSGKG
                     IDEIATVVNKTSDCAIGVNVGDVIVRVDPRYFRPAEVETLLGDPSKAKKLLGWEPEITV
                     EEMCAEMVASDLAKAKQHALLKSHGYDVAVSLER"
     gene            11101..12066
                     /gene="fcl"
     CDS             11101..12066
                     /gene="fcl"
                     /note="O084_10"
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-L-fucose synthetase"
                     /protein_id="BAQ01297.1"
                     /translation="MTKKRIYVAGHRGMVGSAICRQLSQRDDIELVVKTHKELDLTVQK
                     DVDAFFEQEKIDQVYLAAAKVGGIYANNTFPAEFIYQNLMIESNIIHSAHKAGIQKLLF
                     LGSSCIYPKFAEQPMNESALLMGILEPTNEPYAIAKIAGIKLCESYNRQYGRDYRSVMP
                     TNLYGINDNFHPENSHVIPALMRRFHEAKESGAPEVIVWGTGTPMREFLYVDDMAAASV
                     HVMELDEAIYQQNTQPMLSHINVGTGVDCSIREMAETMASVVGYQGKIVFDFTKPDGTP
                     RKLMDVTRLKNLGWQYRYNLHEGLSLTYKWFIGNINSFRG"
     gene            12069..12530
                     /gene="gmm"
     CDS             12069..12530
                     /gene="gmm"
                     /note="O084_11"
                     /codon_start=1
                     /transl_table=11
                     /product="STP|NUDIX"
                     /protein_id="BAQ01298.1"
                     /translation="MNKRLERELFKTIVEHTPLISIDLIIRNDKGEALLGQRLNRPAQN
                     YWFVPGGRIYKDESFEIAFKRITLEELGVQISLNDALFLGVYEHFYNDNFFEAEFSTHY
                     IVHGYEIQLKPQQLHLPTVQHNSYKWFDVVTLLNSTIVHQYTKNYFIPR"
     gene            12536..13942
                     /gene="manC"
     CDS             12536..13942
                     /gene="manC"
                     /note="O084_12"
                     /codon_start=1
                     /transl_table=11
                     /product="GT2_Glycos_transf_2|GT2"
                     /protein_id="BAQ01299.1"
                     /translation="MLLPVVMAGGSGTRLWPLSRTLYPKQFLSLNSRLTMLQETLRRLD
                     KVEHKPALVICNESHRFIVAEQLRKESLKHSGILLEPVGRNTAPAVALAALQAMVTGDD
                     PILLVLAADHEIQDEDNFIAAILAAKNFAEQGKLVTFGIIPTSPETGYGYIKSGESLDG
                     QGYKVAAFVEKPDLHVAQRYISDGGYLWNSGMFMFRASVFIDELKKFRPDILASCQRSL
                     SSSIQDLDFIRLDSASFSCCPEESIDYAVMEKTAEAVVVPLNAQWSDVGSWSALWEISS
                     KDQSGNAIRGDVLVEDATDSYLYSQHRLIGAVGVKDLIVVETKDAVLVAHKDKVQQVKN
                     IVAQLKKNNRTEYLQHREIFRPWGSHDTIAEGPRFQVKHVIVLPGHITAKQIHYHRTEH
                     WIVVSGTAKVHLEDKTYLVSENESTYIPVGVPHAIENPGKIPLEIIEVRSGVYLEEDDV
                     IRVSSSGVGY"
     CDS             13942..14688
                     /note="O084_13"
                     /codon_start=1
                     /transl_table=11
                     /product="putative glycosyltransferase"
                     /protein_id="BAQ01300.1"
                     /translation="MRISIITATYNSEKTLLDTLLSLEKQTHPDIEYIVVDGASKDNTI
                     KLIKRNCTKVSKIICEPDKGIYDALNKGIQVASGDVIGFLHSDDLLAYDDAIADIAKTF
                     ESTGCDAIYGDLEYVAQNDTTKRIRLWKSGSFSRFKMKVGWMPPHPSFYMKRECYSQFG
                     SFSLDYRISADYDSLLRYILKQRISIAYLPKVLVKMRVGGISNRSVSSMVKKSMEDIRI
                     MKQNGIIWPLALAYKNISKLPQFIKK"
     gene            14694..16118
                     /gene="manB"
     CDS             14694..16118
                     /gene="manB"
                     /note="O084_14"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase"
                     /protein_id="BAQ01301.1"
                     /translation="MLNVKKIINDSNIAFGTSGARGLVIDFSHDVCAAFTHAFLSVIDD
                     KYNFNKVALAIDNRPSSYEIAQACAYAIKQHGFEVEYHGVIPTPALAHYSMQKNIPCIM
                     VTGSHIPFDRNGLKFYRPDGEITKEDELAIINSEYTFSPVGVLPHLETSTQGADYYLER
                     YVSLFNPEILKGKRIGVYEHSSAGRDLYAPLFNQMGAEVISLGRSDEFVPIDTEAVSDE
                     DRILAREWSKKYNLDAIFSTDGDGDRPLVADENGEWLRGDILGLLTAIELNIKALAIPV
                     SCNTAIEESNKFASIQRTKIGSPYVIAAFADLAKQFDSVAGFEANGGFLLASDLQINGK
                     ELKSLPTRDAVLPALMLLIASRNSTISQLINNLPQRFTWSDRVKNFPSDSSQQIIKNAI
                     SSPNNFFNSLGYESLSCSAIDETDGARFTLNNGDIIHLRPSGNAPELRCYAEASDENQA
                     KQYVTNVLGNITSLIS"
     gene            16315..17721
                     /gene="gnd"
     CDS             16315..17721
                     /gene="gnd"
                     /note="O084_15"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphogluconate dehydrogenase"
                     /protein_id="BAQ01302.1"
                     /translation="MSKQQIGVVGMAVMGRNLALNIESRGYTVSIFNRSREKTEEVIAE
                     NPGKKLVPYYTVKEFVESLETPRRILLMVKAGAGTDAAIDSLKPYLDKGDIIIDGGNTF
                     FQDTIRRNRELSAEGFNFIGTGVSGGEEGALKGPSIMPGGQKEAYELVAPILTKIAAVA
                     EDGEPCVTYIGADGAGHYVKMVHNGIEYGDMQLIAEAYSLLKGGLNLTNEELAQTFTEW
                     NNGELSSYLIDITKDIFTKKDEDGNYLVDVILDEAANKGTGKWTSQSALDLGEPLSLIT
                     ESVFARYISSLKDQRVAASKVLSGPQAQPAGDKAEFIEKVRRALYLGKIVSYAQGFSQL
                     RAASEEYNWDLNYGEIAKIFRAGCIIRAQFLQKITDAYAENPQIANLLLAPYFKQIADD
                     YQQALRDVVAYAVQNGIPVPTFAAAVAYYDSYRAAVLPANLIQAQRDYFGAHTYKRIDK
                     EGVFHTEWLD"
     gene            17968..19134
                     /gene="ugd"
     CDS             17968..19134
                     /gene="ugd"
                     /note="O084_16"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
                     /protein_id="BAQ01303.1"
                     /translation="MKITISGTGYVGLSNGLLIAQNHEVVALDILPSRVAMLNDRISPI
                     VDKEIQQFLQSDKIHFNATLDKNEAYRDADYVIIATPTDYNPKTNYFNTSSVESVIKDV
                     VEINPYAVMVIKSTVPVGFTAAMHKKYRTENIIFSPEFLREGKALYDNLHPSRIVIGER
                     SERAERFAALLQEGAIKQNIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYAESLG
                     LNSRQIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYQSVPNNLISAIVDANR
                     TRKDFIADAILLRKPQVVGIYRLIMKSGSDNFRASSIQGIMKRIKAKGVEVIIYEPVMK
                     EDSFFNSRLERDLATFKQQADVIISNRMAEELKDVADKVYTRDLFGSD"
     gene            19224..20258
                     /gene="wzz"
     CDS             19224..20258
                     /gene="wzz"
                     /note="O084_17"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen chain length determinant protein"
                     /protein_id="BAQ01304.1"
                     /translation="MAIIAKLWRLKIISSVRVMMRVENNNVSGQNHDPEQIDLIDLLVQ
                     LWRGKMTIIISVIVAIALAIGYLAVAKEKWTSTAIVTQPDVGQIAGYTNAMNVIYGSAV
                     PKVSDIQASLIGRYSTAFSALAETLDNQEEAEKLTIEPTVKNQSLPLAVSYVGETPEGA
                     QKLLAKYIQQVDDQVNEELGKDLKDNIALRMKNLQDSLKTQEVVAQEQKDLRIRQIQEA
                     LQYANQAQVTKPQVQQTEDVTQDTLFLLGSEALESMIKHEATRPLVFSPNYYQTRQNLL
                     DIESLKVDDLDIHAYRYVMKPTLPIRRDSPKKAITLILAVLLGGMVGAGIVLGRNALRN
                     YNAK"
     gene            complement(20355..>20537)
                     /gene="hisI"
     CDS             complement(20355..>20537)
                     /gene="hisI"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyl-AMP cyclohydrolase"
                     /protein_id="BAQ01305.1"
                     /translation="KRIAQKVGEEGVETALAATVHDRFELTNEASDLMYHLLVLLQDQD
                     LDLTTVIENLRKRHQ"
ORIGIN
        1 catcttacgc cagggatttc ataaccagat tatcggtgcc aacatcacca attgtaagtt
       61 cagcgactta caaggcgacg ccattgaatg gaacgtggcg attaacgacc gcgatatttt
      121 gatatccgac catgtcatcg agcgcatcaa ctgtaccaac ggcaaaatca actggggcat
      181 cggcataggc cttgcgggaa gcacttacga taataattac ccagaagatc aggcagtgaa
      241 aaactttgtc gtggcgaata tcacgggatc ggattgtcgg cagttgatcc atgttgaaaa
      301 cggtaaacat tttgttattc gtaatatcaa agcccgcaat atcacgccgg atttcagtaa
      361 gaaagcaggc attgataacg cgacagttgc tatttacggt tgtgacaatt tcgtgattga
      421 taatattgaa atgattaata gcgccgggat gttaatcggc tatggggtaa ttaaaggcaa
      481 atatctctcg ataccgcaga atttccgagt gaataatact caactggata atacccacct
      541 tgcttataaa ttgcgcggca tccaaatctc cgccgggaat gctctctcct ttgtagcgct
      601 gactaacatt gagatgaagc gtgcgtcgct ggagttacac aacaaaccgc aacatctttt
      661 tatgcgaaat atcaaggtga tgcaggaatc ctcagttgga ccagcattga gcatgaactt
      721 cgacatgcgc aaagacgttc gcggcgtctt tatggcgaaa aaagaaacac tgctgtcact
      781 tgcaaatgtt catgcggtga atgaaaaagg gcaaagctcc gtcgatatcg acagagttaa
      841 tcaccatatt gttaatgtgg aaaagattaa ctttagattg ccggaacgga gggagtagat
      901 ttgcgaccat tcctggacaa aatggagcca tacttaggaa caatgctact gcaatccaca
      961 acgaagcggc gtaacatcac aagtaattca gtaatcaatt cagggtaatt gatgctggcg
     1021 aaaaaaatcg aacaagctat aattcagcaa ccattttaca ggtggatgaa ataatgacga
     1081 atttaaaagc agttattcct gtagcgggtc ttgggatgca tatgttgcct gccactaagg
     1141 cgatacccaa agagatgcta ccgatcgtcg acaagccaat gattcagtac attgttgacg
     1201 agattgtggc tgcagggatc aaagaaatcc tcctggtaac tcacgcatcc aagaacgcgg
     1261 tcgaaaacca cttcgacacc tcttatgaat tagaatctct ccttgaacag cgcgtgaagc
     1321 gtcagctgct ggcggaagtg cagtccatct gtccgccggg cgtgaccatt atgaacgtgc
     1381 gtcagggcga acctttaggt ttaggccact ccattttatg tgcacgacct gccattggtg
     1441 acaatccatt tgtcgtggtg ctgccagacg ttgtgatcga cgacgccagc gccgacccgc
     1501 tgcgctacaa ccttgctgcc atgattgcgc gcttcaacga aacgggccgc agccaggtgc
     1561 tggcaaaacg tatgccgggt gacctctctg aatactctgt catccagacc aaagagccgc
     1621 tggaccgcga aggtaaagtc agccgcattg ttgaattcat cgaaaaaccg gatcagccgc
     1681 agacgctgga ctcagacatc atggccgttg gtcgctatgt gctttctgcc gatatttggc
     1741 cggaacttga acacactcag ccaggtgcat gggggcgtat tcagctgact gatgccattg
     1801 ctgaactggc gaaaaaacag tccgttgatg ccatgctgat gacaggtgac agctacgact
     1861 gcggtaaaaa aatgggttat atgcaggcat ttgtgaagta tggactacgc aacctgaaag
     1921 aaggggcgaa gttccgtaaa gggattgaga agctgttaag cgaataatga aaatctgacc
     1981 ggatgtaacg gttgataaga aaattataac ggcagtgaag attcgtggcg aaagtaattt
     2041 gttgcgaatt ttcctgccgt tgttttatat aaacaatcag aataacaacg agttagcaat
     2101 aggattttag tcaaagtttt ccaggatttt ccttgtttcc agagcggatt ggtaagacaa
     2161 ttagcgtttg aatttttcga gtttggcgcg agtgggtaac gctcgtcaca tcgtggacat
     2221 gcatgcagtg ctctggtagc tgtaaagcca ggggcggtag cgtggaaaaa ttaaaatgaa
     2281 actctttgta aaaataaaaa gctgtggatg tcggaatagt aaaagtataa attatcatgg
     2341 ttctatattg agctttataa ctcaacaatg agatatgtat gctgtcaaaa ataaaaaatg
     2401 tgatagatcg gatagttatt atatttaaac caatagcggc agatttgaca cagaaagaaa
     2461 aagatgaagt tattagatta cgtggagttt atctgactgc tatcatatct ttgttgtcaa
     2521 agattatttc tatgatatct atatttataa ctattccggc aatattaaat tacttaggtg
     2581 aggaattgtt cgggatttgg atgacattaa gttccattat tgcgatgttg acttttgcag
     2641 atatggggat tgggaatgga gttgtaaata aattatcaaa agcaatatat agtaatagtg
     2701 taaatgatat aagaaaaatc atcacaaatg ctgttacagt attattgatt atcgcgacat
     2761 caatcaattt attattctat gctgccactc ctttagttag ttggaataga attttgaatc
     2821 tgagtgaaaa aattgactca cattctatag agcatgcttt atttgtattt gttttttgct
     2881 ttagtttaaa tgtgctattt tctatagtac agaaaataca gttggcatat caattggggt
     2941 ttatagcaag tatatggcaa atattaggta gtgtattttc acttggattg ctgtttctgt
     3001 ttattaactt gaagcttgaa atggcttggt tggttttttc aatagctggt atacctgcta
     3061 tatttcaact attaaactat ttgcactttt ctctcgtaat ttgtaaaact ggctttttca
     3121 agataagttt tataaaaata gcagaaatga aatcactatt aagtactggt gtgttatttt
     3181 ttgcattaca gatttccatg gtgtgcactt atacatccga taatatcatc ttaaatacga
     3241 ttattggagc ggaagctgta actgaatata gcgttcatgt gcgattgttt agtgtaattc
     3301 cgatccttat ggggatggtg ttaattccat tatggccagc atactcatca gcaaggataa
     3361 agaaagatat aaaatggatt cgggatgttt ggaataaaag cattatgatg gcattgttag
     3421 tttcagtatt tataggtgga agtattattc tttttttacc tgatattttt gatctctggc
     3481 tgaaaaataa aatacaacct acatataccc tagcttatat gctttttgta tggaaacttt
     3541 ttgaatctgt aggcttagca ataagctgtt ttcttaacgg gatggattta attaaacagc
     3601 aagcattcat tgcagtggta actgcggtag ttgctatctc tttgaagata ttgtttgtat
     3661 atcaaatagg aattactgga gtgcttcttg gaacgctgat tccctttgtt ttattgactt
     3721 ttataccaac attatttata tcattgggct ttttgagaaa aggaatgtgc taatgaaaaa
     3781 gtttatttca agattgctct ataatcctta caaaaagata aaaaaagact ctcgaattga
     3841 atttaattct gggattttgg ataaaaattt ccgtgtgcat ttttactgta gcgaaagtcg
     3901 tgctaaggca tatatcggaa ataattgcat cctaaaaaat gagattatat ttgagagaga
     3961 gtgtggtgtc gtcactattg gtgataatac attcattaac aaaaacacga agattataag
     4021 tgttaataga attagtatag gaagtaatgt taccatatct tatggtgtaa taatatatga
     4081 ccatgattca cactcgctag attatcggga aaggcaaaag gatattctga aaatattaga
     4141 gactcgagat ccaaataatg atatagaaaa taaaaattgg gattgtgtta aaagtttacc
     4201 agtaattata ggtgataacg tttggatagg ttttcaagct gcgatactaa aaggtgttac
     4261 tataggtgag ggcgcggttg ttgctgcaag agcggtagtt acaaaagatg ttccggcgtg
     4321 gtctgtcgtg gcaggcaatc cagcgaaggt tgtgaaagaa ataccaagag atatgaggaa
     4381 gtaagttgaa aaatataact ataatgattt tgggggcagg tggattcatt ggttctcatc
     4441 tgtgtaattc atgtatacaa aatggagcta cagtttatgc acttgggcgt aacttagata
     4501 atgtgaagat caaaaaccag aggtttataa aattaagttc aaatgaaatc actgaaaaga
     4561 cattatttga tgttgcacaa ccagattatg tgtatttttt aatgggcgcg gcatctgtag
     4621 caaaatctat agaagctcca ttatatgact ttaaccagag tttaccccca ctattggtga
     4681 ttttggaaaa attacgaaaa gaatggatag ggacgcgcct catttttatc tcaagtgctg
     4741 cagtatatgg tgaaaatgcg agtgaaagaa caagtgtaag tagtttacct atgcctttat
     4801 ccccttatgg attaaataag aaaatctcag aaacgtatgt gcaatattat atgaaacact
     4861 atgatattag tgcgaaaata ataagacctt tttctgtcta tgggcctggt ttaaagaagc
     4921 aacttatttg ggatgtattg aataaaataa aagataagca gcatcattat tttggtagcg
     4981 gtaatgaaat gcgtgattgg atatatattg atgattttat tgctgttttg tttaattatg
     5041 ttagtaatta tgctttgatg agtgacctga taaatgtagg tacaggtatt ccaataaagg
     5101 ttaaaaatgt tattgaacaa ttgtacacat tgaccgatac atttgaaatt ccctcgttta
     5161 gtgatggtgg taaggaaggc gatccaaagc acttggtaag taattatgag gagcaagatt
     5221 ttttaagaga acttttaaaa acgcctcttg aattgggatt gagaaataca gttgattggt
     5281 ttaaaaacca ggaggaacaa tgttaaaagt cggtattcct gtattgttca gtgagcagca
     5341 ttggatggga gggatcaact actttagaag tctaatttct gctttttcac ttgttgaaca
     5401 aaatgatatt gaacttataa ttttttgtga aaaagatgga ttgttcaata caaccaaact
     5461 taataatgtt cgacaggtaa ttattcctga gcttcttcct agaaaattgt ctaaacgtat
     5521 aataaataaa gtttatggag tgaattttga attatacaaa gctattaaaa atgaaagtgt
     5581 tgacatttta tctcataccc agataaataa acggttagct tgcaaaacca tgtggtggaa
     5641 gcccgatttt caagagaaat actatcctga gttttttaat gagaaagatt tatttctacg
     5701 aaatcagtct gtagttaata atgctttacg tggatatctg ctgtttagta gtaatgatgc
     5761 aaaaaacgat ttttttaagt tctataatac tttgccaacg caaaatatta atgtgcttca
     5821 attcgttcca gaaattgaaa taagcagttc acaagatgaa aatgatagaa taatagcagt
     5881 aaaagaaaaa tatggaatta gtggagatta ttttttttta ccaaaccaat tctggaaaca
     5941 taaaaaccat gaattagtga taaaggccat tattacagga gatatacctg ctaaagtcgt
     6001 ggcaactggg gcatctaatg attatcgtgg agggaggcat atagaattaa tcaatcaatt
     6061 acttaaacaa gattctgcta aaaaattcaa gttattaggg ttagttgata gggatgatgt
     6121 taatcttttg atgaaaggtg ctatagccgt aatcaaccca tctcggtttg aggggtggag
     6181 tacgacggtc gaagaggcaa aatatttagg taaaagatta atattatctg atataccagt
     6241 acaccatgaa caaaatcctc ctgattcatt atatgtatca tgtgatgatg tatcaggaat
     6301 gatttctgct atgcgcaaga taatagatga atatgataca gagaaggaaa tatttcgtgc
     6361 aaagaaggct gctgagcaat ataagtttaa aagaaaggaa tttggtctct catactataa
     6421 tatcttaaag tcactataat atggccatct atatatttat aagcatttca tgtttaatat
     6481 catatgtttt gtcgaataat gataagaatt cattgagtcc aagattcctg ttaataatac
     6541 taactttatt tacggggtta tcttatacaa atggatggga ttggtacggt tatcttgact
     6601 tctataataa cattcaaaat gaaggggtaa gtgcaatata tgagtataat atatatggca
     6661 ttgagtattt atatttaata tatttgtata ttgttggcct aagtggagga agttttagct
     6721 tattcatatt attgaatgca ataataataa attttctcat ttatagtttt tgcaaacgag
     6781 cttatgttaa ttatagcttg ttcatgttta tttttatagc tgcatcatat ttgaggttgg
     6841 aattaagtac tatacgtcaa ggattggccg ttgttatagt tatatattca tattcgcttt
     6901 tattaaactc aaaaataaat ttatccttat tgtttatatt tctggctatt tgctttcata
     6961 gaagcgctgc tatagtatta ttattctttc cgtttgttta ttataatagt gcaagaaata
     7021 ttcattactt tattgtcata cttactatac catttgttat tctttcgggg gaattaaatg
     7081 ttgtatttat aaaaatattg aatgctttta attcatcatt attaaatgca tatatatcga
     7141 agcttataat ttatttgtca ttaaacaaac aagcaattat taacccacaa gctatggcat
     7201 tattagtctt ttattttatt tgtatcaggg tttgtgatgt taaaaacaaa aaacaaatta
     7261 tatttttaaa tataattgct tgtcaggtta taatttcttt ttattttata tttttaacac
     7321 aattgattat tatgcgtctg gtttattatt ttcaagttgg atggatatgt tgggtaataa
     7381 tattatacaa ggagtatttc cgacctaaat ggttatgttt tttccttata tgtcttctgt
     7441 ttattaccaa gtcaatatta aattttagat atgagcaaga tagagcggtt ttttttccat
     7501 attataatgt aatatcttca tacttggatg ataattatgg gagaagtaga tcttttatat
     7561 tgaataaagc agatgagctt tttaaggagt aaaatgtcaa agaaaattaa gtatattata
     7621 aattttgcaa tgtcactttt tatattacca tttttctata tagaaaaaaa gataatcgga
     7681 aaaaaaattt ggttatgtgg cgcaggaaat ggctattatg aaaataacat agctagcatt
     7741 catgattata ttttgaagag tttaccttta gctaaaaata aaattttttt tgtaacaaca
     7801 aatcgggaac ttttaagcgg tgatgtagcc tttcctgtac ttattagagg gcatttaaaa
     7861 acttatgcgt tgagtatttt agctgattat ttaatctttg atacttgtaa ctcagatatt
     7921 gctcctggaa ttcaccggta tctttctgct ttgaaggtaa atgttaatca tggctttgaa
     7981 ggcttaaaga agcttcctga agactattat gcgaaaattg atgctgacat ccattgtgct
     8041 tcttcaatga gagagaaata tattaaggta tttgaatgtg gagcagcgaa tgagaaagta
     8101 tttattacag gttatcctag atttgatcga atcgtttcac gtgaaaacag tcatgtgaaa
     8161 aaaattcttt tctttccaac atggagatca tggttggaga gtctaagcaa tgatgagtta
     8221 aataattcca cgtatgtcag atctatttat gattttctat acagtgagag actcaaagaa
     8281 tatttgagtg aaaataacat tataatgtat tataagccac atcataaaat tagccatttg
     8341 aaattagatt tatcttcttg taaaaatatt attttgctaa aagattatga tgatcttaca
     8401 cattatatat gtgaatcaga tttgcttatt acagattatt caagcgttgc gtgggatttc
     8461 ctttactcta atagagaagt aattttctat atatttgata ttgatgaata tatattaaaa
     8521 caaggtttat actatgatgt cagaacttcc ttaagaaatt atggcggcac acctgatgaa
     8581 attattaatc tccttaaaaa agaacgtaag gaagttgatt taaatttatc aagtatggca
     8641 ggggaatttt ttgagtatcg agataataaa aattctgagc gaattctaaa attaatctgt
     8701 gaatataaga tatgaaagta aaaataattt cttattcttt atccaaaggc ggagcggcaa
     8761 aagcagcaaa aaatttttta catcttgctt cgaaaaacaa aaaatatgaa gcagagatga
     8821 taagtgtatc aggtattata aaaaatggtg ttttatttaa atcatcaaaa ttatcagtgt
     8881 tttggcatta ctcaaaaatg ttagtaagcc gggtactcac ttattttatt ttaaatgata
     8941 aaagtataaa atattcattg aatatttttg actctaatta tgttttaaaa catatcagag
     9001 tggaagatgg gcaaagggaa gttatccata ttaattgggt gaataatgat accctatctt
     9061 tattttcatt aagtaaatta tttgaaaata aaagaaaaag aataatatta acgttacatg
     9121 atgaatggtt ttattgtgcg tcagagcact atgctaaata taattcatta tgttatgtaa
     9181 caggatatga tgatagcaat tttattaata gctatatttt tgaattaaaa aagagaataa
     9241 attttgagaa tgtcgtaatt accgttccat catattggtt gtatgagcga gcaaagaaaa
     9301 gttatttgtt aagtaattgt gatatatata tattgcctaa ttatatcgat actaatattt
     9361 ttacagagtt aaaggacatt cgttcaaaac gttatagaat acttgatgtt cctgaggatg
     9421 cttttattat tggatttggt gctgttagtg gcggtgccaa ccccttgaag gggtttgatc
     9481 tcttggtttc tgccttggat gaagtattaa gtaaaataaa tgacaaagct agaattgtaa
     9541 tggtgacgtt cggtgctaac gatatagata aacgtgtaac atcactggga tgccacatta
     9601 taaatatggg agttatctct aacagccata atatggctga gatttataat tatttggatg
     9661 tcatgattgt tccttcacgc gttgaatcct ttgggcaagt agctgctgaa agtttagctt
     9721 gtaaaacccc ggttattgca tttgattatt caggaattaa agatattgtt actcatcaac
     9781 ggagtggttt attagctgaa ccattttctg ttgattcact cgcactaaat ataaattcat
     9841 ttatgaatat gacggagaaa gagagatatg tatatggtga aaatggtcgc gatgatgtag
     9901 ttcgaaaatt tggagaaacg gtggtttcag aaatttattt taaattgata gattatgtta
     9961 gaggagatga atatgaaaaa taaagtagct ctaattactg gtgttaccgg tcaagatggt
    10021 tcttacttgg cagaatttct tcttgaaaag ggttatgaag tgcacggtat aaaacgccga
    10081 gcatcttctt ttaatactga acgtgtagat catatctatc aggatcgtca taatgaaaac
    10141 ccagatttca tacttcatta tggtgactta acggactcat caaacctgat acgcttgatt
    10201 aaagaaatcc aaccagatga agtttataac cttggagcac aatctcatgt agcagtttca
    10261 tttgaatcac ctgaatatac tgctgatgta gatgctatgg ggactttacg tctgctggaa
    10321 gcgatccgta tttgtggact agagaaaaag acgcgtttct atcaggcatc aacttctgaa
    10381 ctcttcggct tagtccaaga aattccgcag cgagaaacta caccgttcta tcctcgttcg
    10441 ccttatgctg ttgctaagat gtatgcatac tggattacta taaactatcg tgaatcttat
    10501 ggtatgtatg cctgtaacgg tatcttgttc aaccacgaat ctccacgtcg tggcgaaaca
    10561 tttgttacac gtaaaattac tcgtgcaatt gctaatgttt cgcaaggaat cgaaaaatgt
    10621 ctctatcttg gtaacatgga ctcattgcgt gactggggac atgctaaaga ttatgtccgt
    10681 atgcagtgga tgatgcttca acaagaacgc ccggaagatt ttgtaatcgc taccggtaaa
    10741 caaatttctg tacgtgaatt tgtccgaatg gcggctaaag aagttggctt ggaacttcag
    10801 ttctctggta aaggtattga tgaaatagct actgttgtaa acaaaacatc tgactgtgct
    10861 attggcgtaa atgttgggga tgtaattgtt cgtgttgatc cacgctattt ccgccctgcg
    10921 gaagttgaaa cacttcttgg tgatccaagt aaagctaaaa aattattggg ttgggaacca
    10981 gaaattactg ttgaagaaat gtgtgcggaa atggttgcca gtgatctggc gaaagcaaaa
    11041 cagcatgcac tactgaaaag ccatggttac gatgttgcag tttctctgga gcggtaaggt
    11101 atgacaaaaa aacgtatcta cgttgctggt caccgaggta tggttggctc tgctatttgc
    11161 cgtcaattat cacagcgtga tgatatcgaa ttagtggtca aaacacacaa agaactcgat
    11221 ctaaccgtac agaaggatgt tgatgcattt tttgagcaag agaaaattga tcaggtttat
    11281 cttgctgcgg ctaaagttgg tggcatttat gccaacaata catttccggc agaattcatc
    11341 tatcagaatc tcatgattga gagtaatatt attcattcag ctcacaaggc cggaattcaa
    11401 aaattacttt ttttaggctc aagctgtatt tatcctaaat tcgcagagca gccgatgaac
    11461 gagtcagcgc ttttaatggg catacttgag ccaactaatg aaccatacgc aattgctaaa
    11521 attgcgggca taaaattatg tgaatcttat aaccgccaat atggccgtga ttatcgcagt
    11581 gtaatgccta ctaatcttta tggcataaat gataatttcc atcctgaaaa ctctcatgtt
    11641 attccggcac tcatgcgtag attccatgaa gcaaaagaga gtggtgcgcc agaggttatt
    11701 gtctggggaa ccggaacacc gatgcgtgag tttttatatg ttgatgatat ggctgccgca
    11761 tccgtccatg taatggagct tgacgaagca atttatcaac aaaatacaca gcctatgtta
    11821 tcccatatta atgttggtac gggtgtagat tgttctatac gtgaaatggc tgaaacaatg
    11881 gcctctgtgg tgggttatca aggtaaaatt gtttttgatt ttactaaacc tgatggcact
    11941 ccgcgtaaac ttatggacgt tacccggctc aaaaacttgg gctggcaata tcgctataat
    12001 ttacatgaag gcttatcatt aacttataaa tggtttattg ggaatattaa ttcttttcgg
    12061 ggatagttat gaacaagaga ttggaacgtg agctatttaa aacaatagtt gagcatactc
    12121 ctctaatctc gattgatctc ataattagaa acgataaagg agaggcgctg ctggggcagc
    12181 gcctgaatcg cccagcacaa aattattggt ttgtgccagg agggcgaatt tataaggatg
    12241 agtcattcga gattgcattt aagcggataa cacttgaaga gttgggcgtt caaattagtc
    12301 ttaatgatgc cttatttctt ggggtgtatg aacattttta caatgataat ttttttgaag
    12361 cagaattttc tacacactat atagtgcatg gatatgaaat ccaacttaaa cctcagcaac
    12421 ttcacctacc aacggtccag cataattcct acaagtggtt tgatgtagta acgttgctta
    12481 atagcactat agttcatcaa tataccaaaa actattttat accaaggtaa tagatatgct
    12541 acttcccgtt gtcatggccg gtggttctgg taccagatta tggcctcttt cacgtacact
    12601 ttatccgaaa caatttctgt ctttaaatag tcgtttaacc atgttgcaag agacattgcg
    12661 gcggcttgat aaggtcgaac ataaacctgc tttggtcatt tgtaacgaat cacatcgctt
    12721 tatcgttgct gaacaattgc gtaaagagag tttaaagcat agcggtattt tgcttgagcc
    12781 tgttggtcgt aatactgcgc ctgctgtagc acttgcagca cttcaggcta tggtaactgg
    12841 agacgatcct attcttttgg ttcttgctgc tgatcatgaa atccaggatg aggataattt
    12901 cattgctgca attctcgctg caaagaattt tgcagagcag ggtaagcttg ttacgtttgg
    12961 tattattcca acatccccag agactggcta tggttacatt aagtcaggtg aatctctgga
    13021 tggacaaggt tacaaagttg cggcttttgt tgaaaaacca gatcttcacg tagctcagcg
    13081 gtacatatca gatggcggtt atctttggaa tagcgggatg tttatgttca gagcatctgt
    13141 atttatcgat gaactgaaaa aattccgacc agatatttta gccagttgcc aacgctcctt
    13201 gtcctcttcg atacaagatt tagattttat ccgtctggat agtgcttcat tttcttgctg
    13261 tcctgaagag tctattgact atgcagttat ggaaaaaaca gccgaagctg tcgtcgttcc
    13321 attaaatgca caatggagtg atgttgggtc atggtctgca ttgtgggaaa taagttcaaa
    13381 agatcaaagc ggtaatgcca ttcgtggtga tgtattggtt gaagatgcta cagatagtta
    13441 tctttattcg cagcatagac ttattggtgc cgtgggcgta aaggatttga ttgttgttga
    13501 aacgaaagat gccgtattag ttgctcataa agataaagtt cagcaagtta aaaacatcgt
    13561 cgctcaactt aaaaagaata atcgcacaga atatttacag catcgggaaa tatttcggcc
    13621 ttggggcagt catgatacta tagctgaagg gccgcgcttt caagtgaaac atgtgattgt
    13681 attgcctggt cacattaccg ctaagcagat tcattaccat cgtactgaac attggattgt
    13741 tgtctcgggg acagctaaag ttcatcttga agataagact taccttgttt ctgaaaatga
    13801 atcaacatat atacctgttg gtgttccaca tgccattgaa aatcctggca agatcccgct
    13861 tgaaataatt gaggttagat caggagtcta cctggaagag gatgatgtta taagagtttc
    13921 ttcttctgga gtaggatact aatgcgaatt tctattatca cagccactta taatagtgaa
    13981 aaaactctcc ttgatacatt actttctcta gaaaaacaaa cgcatccaga tatcgaatat
    14041 atagttgtag atggagcatc gaaagataat acaattaagc tgatcaagag gaattgtaca
    14101 aaagtttcaa aaatcatttg cgaacccgat aagggcattt atgatgctct gaataaaggt
    14161 attcaagtag cttcgggtga tgttattggc tttttacatt ctgatgattt actagcttat
    14221 gatgatgcta ttgcagatat agcaaaaaca tttgaaagta cagggtgtga tgctatttat
    14281 ggcgatttgg agtatgttgc ccaaaatgat acgactaaac gtattagatt atggaaaagt
    14341 ggttcattta gtcgtttcaa gatgaaagtg ggttggatgc caccacaccc atcattttat
    14401 atgaaacgcg aatgttatag tcagtttggt agtttttctt tagattatcg aatatctgct
    14461 gattatgact cattattacg atatatttta aaacaacgta tttcgatagc atatttacca
    14521 aaagtcttag tgaagatgcg tgttggtgga attagcaatc gttcagtatc ttcaatggtc
    14581 aagaagtcaa tggaagacat tcgtattatg aaacagaatg gtattatctg gccacttgct
    14641 ttagcgtata aaaatatatc caaacttcct caatttatta aaaagtaatc atcatgttaa
    14701 atgttaaaaa aatcattaac gatagtaata ttgcgttcgg tactagtggt gctcgcggtt
    14761 tagtgatcga tttttcccat gatgtttgtg ctgcgttcac tcatgcgttt ctttctgtta
    14821 ttgatgacaa atacaatttt aataaagttg ccttagccat tgataaccgt ccaagtagtt
    14881 acgaaattgc tcaggcatgc gcgtatgcta taaaacaaca tggattcgag gttgaatatc
    14941 atggtgtaat tccgactcct gcattagctc attattcgat gcagaaaaac attccctgca
    15001 taatggtcac agggagtcat atccctttcg atcgtaatgg cttaaaattc tacagacctg
    15061 atggtgaaat cactaaagag gatgagctcg caattataaa tagtgagtat acattttcgc
    15121 ctgtaggtgt attacctcat cttgaaacaa gcactcaagg tgcagactac tacctcgagc
    15181 gttatgtttc tctttttaat cccgagattt taaaggggaa aagaataggg gtatatgaac
    15241 attctagtgc gggacgcgat ttatatgctc ctctttttaa tcaaatgggt gcagaggtca
    15301 tttccctcgg taggagtgat gagttcgttc cgattgatac ggaagcagta agcgatgaag
    15361 atcgtatact tgcaagagag tggtctaaaa aatataatct tgatgctatt ttctcaacag
    15421 atggcgatgg tgatcgtcct ttagttgccg atgaaaatgg tgaatggtta agaggcgata
    15481 ttctgggact acttactgct attgaactta atatcaaggc gttggctatt ccagtgagtt
    15541 gtaatacagc aattgaagag tctaataaat ttgcaagtat acaacgaacg aaaataggtt
    15601 ctccttatgt aattgcagca tttgcagatc ttgctaagca atttgattca gtcgctggtt
    15661 ttgaagctaa tggtggtttt ctccttgcct ctgatttaca aattaatggc aaggaattaa
    15721 aatcgttacc tacacgagat gctgtgttac cagcattaat gctcttaata gcttctcgca
    15781 atagtactat ttctcaactg attaataatc ttcctcagcg attcacttgg tcagatagag
    15841 ttaaaaactt cccttcagat tcaagtcaac aaattataaa aaatgccata tcgtcaccca
    15901 ataatttctt taatagttta ggttatgaat cattatcctg ttccgctatt gatgaaacgg
    15961 atggtgcaag atttacttta aataatggtg atattataca tctccgtcct tccggtaatg
    16021 ctccagaact ccgttgttat gctgaggcca gtgatgaaaa tcaggctaag caatatgtta
    16081 cgaatgtgct gggaaatatt acctctttga tttcttgatg ttataggttt atctacgctt
    16141 atatgtgtgc gtaggtttga ttacacgtag atgccggtat acagaattga agaacggtat
    16201 ttgttgcatt aatgaaattc agcactacac acattcgtgc aacttgagat aacatctcaa
    16261 tcatattcaa gtcgcgcata catcgcggtg aacaccccct gacaggagta aacaatgtca
    16321 aagcaacaga tcggcgtcgt cggtatggca gtgatggggc gcaaccttgc gctcaacatc
    16381 gaaagccgtg gttataccgt ctctattttc aaccgttccc gtgagaaaac ggaagaagtg
    16441 attgccgaaa atccaggcaa gaaactggtt ccttactata cggtgaaaga atttgttgaa
    16501 tctttggaaa cgcctcgtcg catcctgtta atggtgaaag caggtgcagg cacggatgct
    16561 gctattgatt ccctcaagcc atacctcgat aaaggtgaca ttatcattga tggtggtaat
    16621 accttcttcc aggacaccat tcgtcgtaat cgtgagcttt ctgccgaagg ttttaacttc
    16681 attggtaccg gtgtttccgg cggtgaagaa ggtgcgctga aaggtccttc cattatgcct
    16741 ggtgggcaga aagaagccta tgaacttgtt gcgccgatcc tgaccaaaat cgccgcagtg
    16801 gctgaagacg gtgagccatg cgttacctat attggtgccg atggtgcagg tcactatgtg
    16861 aagatggttc acaacggtat tgaatacggt gatatgcaac tgattgctga agcctattct
    16921 ctgcttaaag gtggcctgaa cctcaccaac gaagaactgg cgcagacctt taccgagtgg
    16981 aataacggtg aactgagcag ctacctgatc gacatcacca aagatatctt caccaaaaaa
    17041 gatgaagacg gtaactacct ggttgatgtg atcctggatg aagcggctaa caaaggtacg
    17101 ggtaaatgga ccagccagag tgcgctggat ctcggcgaac cgctgtcgct gattaccgag
    17161 tctgtatttg cacgttatat ctcttctctg aaagatcagc gtgttgccgc atctaaagtt
    17221 ctctctggcc cgcaagcaca gccagctggc gacaaggctg agttcatcga aaaagttcgt
    17281 cgtgcgctgt atctgggcaa aatcgtatct tacgcccagg gcttctctca gctgcgtgct
    17341 gcgtctgaag agtacaactg ggatctgaac tacggcgaaa tcgcgaaaat tttccgtgct
    17401 ggctgcatca tccgtgcgca gttcctgcag aaaatcaccg atgcttatgc cgaaaatccg
    17461 cagatcgcta acctgctgct ggctccgtac ttcaagcaaa ttgccgatga ctaccagcag
    17521 gcgctgcgtg atgtcgttgc ttatgcagta cagaacggta tcccggttcc gaccttcgct
    17581 gctgcggttg cctattacga tagctaccgt gccgctgttc tgcctgcgaa cctgatccag
    17641 gcacagcgtg actatttcgg tgcacatact tataagcgca ttgataaaga aggtgtgttc
    17701 catactgaat ggctggatta atcttattta actaacaata aattgaggcc tggcgtatat
    17761 tgcgccgggc tttttttgcc aattatctta tagactaaat ttcactgctt aatattaact
    17821 taataaatat cagctattct tataaagaaa atctgaattg tttttcgttg cgttgaccat
    17881 ctgacaacgt agcgttaaaa cttttagctc ttatcaggat gctaaaaaca tcatgattca
    17941 cagttaagtt aattctgaga gcatgaaatg aaaatcacca tttctggtac tggctatgta
    18001 ggcttgtcaa acgggcttct aatcgcacaa aatcatgagg ttgtggcatt agatatttta
    18061 ccgtcacgcg ttgctatgct gaatgatcgg atatctccta ttgttgataa ggaaattcag
    18121 cagtttttgc aatcagataa aatacacttt aatgccacat tagataaaaa tgaagcctac
    18181 cgggatgctg attatgtcat catcgccact ccaaccgact ataatcctaa aactaattat
    18241 ttcaatacat ccagtgtaga atcagtaatt aaagacgtag ttgagataaa tccttatgcg
    18301 gttatggtca tcaaatcaac ggttcccgtt ggttttaccg cagcgatgca taagaaatat
    18361 cgtactgaaa atattatttt ctctccggaa tttctccgtg aaggtaaagc cctttacgat
    18421 aatctccatc cgtcacgtat tgtcatcggt gagcgttcag aacgtgcaga acgttttgct
    18481 gcgttattac aggaaggcgc gattaagcaa aatatcccga ccctgttcac cgattcaacc
    18541 gaagcagaag cgattaaact gtttgctaat acctatctgg cgatgcgcgt ggcgtacttt
    18601 aatgaactgg atagctacgc agaaagttta ggtctgaatt cccgtcaaat aatcgaaggc
    18661 gtttgtctcg acccacgtat tggcaaccat tacaacaatc cgtcgtttgg ctatggtggt
    18721 tattgtctgc cgaaagatac caagcagtta ctggcgaact accagtctgt gccgaataac
    18781 ctgatttcgg caattgtcga tgcaaaccgc acgcgtaaag attttattgc cgatgccatt
    18841 ttgttacgca agccgcaagt ggtgggtatt tatcgtctga ttatgaagag cggctcagat
    18901 aacttccgtg cgtcttccat tcaggggatt atgaaacgta tcaaggcgaa aggcgttgaa
    18961 gtgatcatct acgaaccggt gatgaaagaa gattcattct tcaactctcg gctggaacgt
    19021 gatctcgcca ctttcaaaca acaagccgac gtcattatct ccaaccgtat ggcagaagag
    19081 cttaaggatg tggcagataa ggtctacacc cgcgatcttt ttggcagcga ctaacatcct
    19141 gttatcaggg cgattttcgc cctgattctc ttatgttccc tttgtagtaa ttcattcttt
    19201 ttatcattta tcctatagca ttcatggcga ttatcgctaa actatggcga cttaaaatta
    19261 tttcgtccgt tagggtaatg atgagagtag aaaataataa tgtttctggg caaaaccatg
    19321 acccggaaca gattgatttg attgatttac tggtgcagtt gtggcgcggc aagatgacaa
    19381 ttatcatctc tgtcattgtc gctattgccc tggctatagg gtatctggcc gttgccaaag
    19441 aaaagtggac ttccacagct atcgttactc aacctgatgt ggggcaaatc gctggttata
    19501 ccaacgcgat gaatgtgatc tacggatcgg ctgtaccgaa agtctccgac attcaggctt
    19561 cgcttatcgg acgttacagc actgcattct cagcattagc ggaaacgctg gataaccagg
    19621 aagaagcaga gaagctgacc attgagccta ccgttaaaaa ccagtcgtta ccattggcgg
    19681 tgtcttatgt tggtgaaaca cctgaaggtg ctcagaagct gctggcgaag tatatccagc
    19741 aagttgacga ccaggtaaat gaagaactgg gaaaagacct gaaagacaac atcgcgctgc
    19801 gtatgaaaaa cttgcaggat tctctgaaaa ctcaggaagt agttgcgcag gagcagaaag
    19861 atctgcgtat ccgtcagatt caggaagcgt tgcagtatgc gaatcaggcg caggtgacaa
    19921 agccacaggt tcagcagact gaagatgtga cacaagatac gttgttcctt ttggggagcg
    19981 aagcgctgga gtcgatgatt aagcatgaag cgactcgtcc gttggtgttc tcaccaaact
    20041 actatcagac acgtcaaaac ctgctggata tcgaaagctt aaaagttgat gatcttgata
    20101 ttcatgctta ccgctatgtg atgaaaccga cgttacctat tcgtcgcgat agcccgaaaa
    20161 aggcaatcac tttgattctg gcggtgctgc tgggcggcat ggttggcgcg gggattgtgc
    20221 tggggcgtaa cgctctgcgt aattacaacg cgaagtaatc tttgcagctt taaagaaaac
    20281 gggcagggtg gtgacacctt gcccgttttt tttgccggat gcgacaacaa tatcgcatcc
    20341 gcttaccccg caactcactg atgccgttta cgcaggttct caatcaccgt cgttaagtcc
    20401 agatcctgat cctgcaacag caccagcagg tgatacatca aatcagatgc ctcgttggtc
    20461 agctcaaagc ggtcatgtac cgttgcggca agtgcggttt ccaccccttc ttcgcccact
    20521 ttctgcgcaa tgcgttt
//
