LOCUS       NC_011898              23478 bp    DNA     linear   CON 04-FEB-2020
DEFINITION  Ruminiclostridium cellulolyticum H10, complete sequence.
ACCESSION   NC_011898
VERSION     NC_011898.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN00623037
            Assembly: GCF_000022065.1
KEYWORDS    RefSeq.
SOURCE      Ruminiclostridium cellulolyticum H10
  ORGANISM  Ruminiclostridium cellulolyticum H10
            Bacteria; Firmicutes; Clostridia; Clostridiales;
            Hungateiclostridiaceae; Ruminiclostridium.
REFERENCE   1  (bases 1 to 23478)
  AUTHORS   Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Dalin,E.,
            Tice,H., Bruce,D., Goodwin,L., Pitluck,S., Chertkov,O., Saunders,E.,
            Brettin,T., Detter,J.C., Han,C., Larimer,F., Land,M., Hauser,L.,
            Kyrpides,N., Ivanova,N., Zhou,J. and Richardson,P.
  CONSRTM   US DOE Joint Genome Institute
  TITLE     Complete sequence of Clostridium cellulolyticum H10
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 23478)
  AUTHORS   Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Dalin,E.,
            Tice,H., Bruce,D., Goodwin,L., Pitluck,S., Chertkov,O., Saunders,E.,
            Brettin,T., Detter,J.C., Han,C., Larimer,F., Land,M., Hauser,L.,
            Kyrpides,N., Ivanova,N., Zhou,J. and Richardson,P.
  CONSRTM   US DOE Joint Genome Institute
  TITLE     Direct Submission
  JOURNAL   Submitted (06-JAN-2009) US DOE Joint Genome Institute, 2800 Mitchell
            Drive B100, Walnut Creek, CA 94598-1698, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/04/2020 07:32:10
            Annotation Pipeline               :: NCBI Prokaryotic Genome
            Annotation Method                 :: Best-placed reference protein
            Annotation Software revision      :: 4.11
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
            Genes (total)                     :: 3,537
            CDSs (total)                      :: 3,447
            Genes (coding)                    :: 3,334
            CDSs (with protein)               :: 3,334
            Genes (RNA)                       :: 90
            rRNAs                             :: 8, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 113
            CDSs (without protein)            :: 113
            Pseudo Genes (ambiguous residues) :: 0 of 113
            Pseudo Genes (frameshifted)       :: 37 of 113
            Pseudo Genes (incomplete)         :: 81 of 113
            Pseudo Genes (internal stop)      :: 17 of 113
            Pseudo Genes (multiple problems)  :: 20 of 113
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence was derived from
            CP001348.
            URL -- http://www.jgi.doe.gov
            JGI Project ID: 4002584
            Source DNA and bacteria available from Jizhong Zhou
            (jzhou@rccc.ou.edu)
            Contacts: Jizhong Zhou (jzhou@rccc.ou.edu)
            David Bruce (microbe@cuba.jgi-psf.org)
            Annotation done by JGI-ORNL and JGI-PGF
            Finishing done by JGI-LANL
            Finished microbial genomes have been curated to close all gaps with
            greater than 98% coverage of at least two independent clones. Each
            base pair has a minimum q (quality) value of 30 and the total error
            rate is less than one per 50000.
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. it is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376).
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Annotation Pipeline (PGAP)
            set; GeneMarkS-2+
            repeat_region
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..23478
                     /organism="Ruminiclostridium cellulolyticum H10"
                     /mol_type="genomic DNA"
                     /strain="H10"
                     /culture_collection="ATCC:35319"
                     /type_material="type strain of Ruminiclostridium
                     cellulolyticum"
                     /db_xref="taxon:394503"
     gene            1..1608
                     /locus_tag="CCEL_RS06160"
                     /old_locus_tag="Ccel_1229"
     CDS             1..1608
                     /locus_tag="CCEL_RS06160"
                     /old_locus_tag="Ccel_1229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004617602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH43|CBM6|GH43_16"
                     /protein_id="WP_015924734.1"
                     /translation="MFKKIKKFSVFMVALLFLSVYSFNLVFADYPIFYQRYTADPSGLE
                     ANGRLYLYSSHDVYDPNKPGYIMNDITCISTDDLKNWTDHGEVFKASGWASLSWAPVVV
                     AKNNKYYMYFGNGAGGIGVSVSDSPTGPFKDALGKALINGSTPGVNPPSGFWCFDPGAF
                     VDDNGQAYLYFGGNGEGNTRVIKLNSDMISLNGSASGITAPIFFEDSWIHKYNGKYYYS
                     YSTNFSKGAATIDYMMSDNPITGFQYKGTVLANPPLNEGNNNHHTIFPFKGDWYIAYHN
                     RALAIANGAASGDARTYQRSVCIDKLNYNADGTMQKVTITTDGLKQLKYVNPYVTNEAE
                     TMAQGSGINTEECTEGGRDVAFIENGDWIKVRGVDFGTAGAASFDARVASSTSGGNIEI
                     RLDSLTGKLVGTCVVENTSGWQNWTTKTCSVSGTTGVHDLYLKFTGDSGYLFNLNSWRF
                     NTSGAKTVYGDLDGSGDINAIDFSLMKQYLLGSITKFPIEDGIIAADLDASGTIDAIDY
                     VLLKEYLLGKRTQFPAEL"
     gene            1714..3339
                     /locus_tag="CCEL_RS06165"
                     /old_locus_tag="Ccel_1230"
     CDS             1714..3339
                     /locus_tag="CCEL_RS06165"
                     /old_locus_tag="Ccel_1230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020815939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH10|CBM6"
                     /protein_id="WP_015924735.1"
                     /translation="MLSKRKTRKFRIFSTLFVALLCATIITSSFPLTADAAMATGKAKF
                     VGNIWYDGNAPSKYADYWNQITPENATKWGPCEPQQGVYNFSQAKAMYNYCKTNKIPFK
                     FHTLIWGSQYPNWLNNLSGTARKTAIENWYKAAAQNFPDAEYIDVVNEAMPGHAPFPFK
                     NDIGGDNGLYGTGWDWIVWSFEMARKYFPNSKLLINDYNVLNEWSCLDQYIPVVKILKA
                     RNLIDGVGCQSHGLEKTSAANLKSRLDRLAATGVPIYISELDLDIADDNTQKNKMQELF
                     PVMYEHSAVKGITIWGYLQGRTWIPNSHLLRSDGSERPAMTWLKQYMAKVPGEDVPVET
                     RSAFSKLEAESYNDQSGIQNVTCYEGTEAVGYTENGDYTVYKNIDFSNGATSFQARVSS
                     ATTGGNIEIRLDSATGTLIGTCPVAGTGDWQKFLDAKCTVSGVSGKHDLYLKFTGGSGY
                     LINLNWFMFSNTPVSTDKIGDLNSDGQIDALDFQVLKKCILGTGTIENTKLADLDANGT
                     IDALDFVLMKQYLLGQITKFPADK"
     gene            3407..4981
                     /locus_tag="CCEL_RS06170"
                     /old_locus_tag="Ccel_1231"
     CDS             3407..4981
                     /locus_tag="CCEL_RS06170"
                     /old_locus_tag="Ccel_1231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014312551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH43_29|GH43|CBM6"
                     /protein_id="WP_015924736.1"
                     /translation="MKKVSKIAALLLVLTLFIPTVGYADNPIVQTLYTADPAPMIYNDT
                     CYVYTGHDEDTLVNDFFTMNDWRCYSSTDMVNWTDNGSPLSYSSFSWAKGDAWAGQCIQ
                     RNGKFYYYVPLTPKTGGTAIGVAVSDSPTGPFKDPLGKPLVSTGSGDIDPTVYIDDDGQ
                     AYLYWGNPNLYYVKLNQDMVSYSGSIVKVPLTTASFGTRSKTDRPTTYEEGPWFYKRNS
                     LYYMVFAGGPISEHIGYSTSTGPTGPWTYRGKIMPTQGSSFTNHPGVADFKGNSYFFYH
                     NGALQGGGGFHRSVCVEQFKYNADGTFPTINMTTTGSTQIGNLNPFIKTEAETICWESG
                     IETEKCSEGGMNVAFIENGDYIKVKGVDFGTGAAAFTARVASATDGGNLELRLDSPTGK
                     LVGTCAVTSTGGWQTWVDKTCTVSGAEGIHDLYLKFTGGSGYLFNFNWWKFIKAGNTSV
                     IGDLNGDKSVDAADYAMMKKYLLGLIEDFPAENDIEAGDLNKDSVIDALDFAVFKKYLL
                     GTIPSLP"
     gene            5004..6476
                     /locus_tag="CCEL_RS06175"
                     /old_locus_tag="Ccel_1232"
     CDS             5004..6476
                     /locus_tag="CCEL_RS06175"
                     /old_locus_tag="Ccel_1232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014312552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CE1|CBM6"
                     /protein_id="WP_015924737.1"
                     /translation="MIKNILTKKTIWGMVAFVFALTLVFTVPDSKVQAAALPTTPPTGY
                     DRVQSNIPHGQVSYINYQSKATNSQRRARIYLPPNYSADKKYSVMYLLHGIGGNEDEWY
                     NNGAPNVILDNLIAAGKIQPFIVVLPNGNATGTGVSDGWTNFTKDLIESLIPYIESNYS
                     VYTDRNHRTVCGLSMGGGQSFNIGLPNLNLFPYVGAFSPAPNTLPNSQLFPNDGASAKQ
                     LLKFLFISYGTTDSLISFGTGVHNYCDSQSIPNTYFLIQGAGHDWNVWKQSLWNYSQMI
                     CEKGFTDYGPVAPVSAFTQIEAESFTSQSGVQTETCTEGGLNVGYIENGDYVVYNNVDF
                     GSGATSFQARVASAGNGGNIEIRLDSITGPLVGTCAVKGTGDWQTWTDAKCTVSGVTGK
                     HDLYLKFTGGSDYLMNFNWFKFGNATQTLTGDLNGDASEDATDYALLKKYLLGQINDFP
                     VEDDINAGDMNKDGVIDALDFAVFKKILLGTI"
     gene            6552..8792
                     /locus_tag="CCEL_RS06180"
                     /old_locus_tag="Ccel_1233"
     CDS             6552..8792
                     /locus_tag="CCEL_RS06180"
                     /old_locus_tag="Ccel_1233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014312553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH43_10|CBM6"
                     /protein_id="WP_015924738.1"
                     /translation="MQFKKVFSILLLVCLLVTQTTIVGAWQSDNDNGTYTNPILNADYP
                     DIYAIRVGSDYYMVSSTFVSFPSIPILHSKDLINWEIIGYVSSDLNGTGKSYNLTNTFD
                     DYGHGCWAPSIAYRNGTYYVGIYQAQGKFIMCTATNPAGPYTKTVYNQGFHDPALFIDD
                     DGTGYIVSEANDVKVTKLSADYKSVVNSQVTTRIEGATGNYLVEGTHVMKKNGYYYIFR
                     NSTPPESYTYCLRSKSIYGPYEMRILLNGPSISGGSQIHQGGPIDTTTGEWWFYVFQDG
                     QGLGRRDILIPMQWQNDWPILGDPSTVKNVSIAGKTYPMGTVPVTYKKPDVGATYPILT
                     IPNSDEFSSTTMGVQWQWNHYPDNTKWSLSERPGYLRLHAKNANNLWRATNTLTQRVEG
                     PDCQGTIELDTTNMLDGDNAGLCLLNIPYGTIGVSKSGGVKRIVANINAKKDTAGTITN
                     GPTLTGNTVYLRAKADLISNKATFFYSTDNVNFTQLGGTLSMPFDLGFFQGDKFGIFNY
                     TTASSGGYADINWFRYYTSAGPNTPIPDITLSAFEKIEAESYNSQSGIQNVTCDEGTEA
                     VGYTENGDYVVYKNVDFGSGANGFNARVSSATVGGTIEIRLDSANGTLIGSCPVAGTGG
                     WQAFTDANCTVSGVSGKHDLYLKFTGESGYLFNINWFKFSNTSVISDKLGDVNSDGQID
                     AIDLQLIKKYILGLGEIENIKTADLDGNGDVNAIDFSLMKQYLLGLITEFPG"
     gene            8876..10486
                     /locus_tag="CCEL_RS06185"
                     /old_locus_tag="Ccel_1234"
     CDS             8876..10486
                     /locus_tag="CCEL_RS06185"
                     /old_locus_tag="Ccel_1234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014312554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH62|CBM6"
                     /protein_id="WP_015924739.1"
                     /translation="MNIFKKGFSIFLGLFMIISSFGSMVNAAANPNPSWNVDERVIFHN
                     QCSPYDYYAAKDPTIVYYNGKYLVYYTGANKSGGWQMCFTSASTISGLKTAPRTYMSKI
                     GESYFCAPELFYYEPQKLWYLVYQDGTHGAAYATTTTPDDPNSWSGPKSFGISGNMGWD
                     YYIICDDQYAYMYNTPSDGSGKLYMRKTTLANFPNKGWSTPTVACSNVFEGAAVYKSLA
                     DGQYYMLIEAMIDGRSYELFTSSSAGGPWTLVNNKWATRSNLTKYNADKWTTNVSHGEL
                     IRAGYNQKLEINDINKVDFLIQGTTNMNAEYQQIIWDLGLIRNYTGSPDTPVTPRTAFE
                     KIEAESWNDQSGIQNVTCDEGTEAVGYTENGDYSVYKSIDFGSGATSFQARVSSATSGG
                     KIEIRLDSATGTLVGTCTVSGTGSWQTFADVNCTVSGVSGKHDLYLKYIGDSGYLINLN
                     WFKFSNTPVVSDKLGDVNSDGQIDAIDLQLLKKYLLGSGTIENTKLGDLNASGDVDAID
                     FSLLKQYLLGQITKFPAQA"
     gene            10561..12090
                     /locus_tag="CCEL_RS06190"
                     /old_locus_tag="Ccel_1235"
     CDS             10561..12090
                     /locus_tag="CCEL_RS06190"
                     /old_locus_tag="Ccel_1235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014312555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH43_29|GH43|CBM6"
                     /protein_id="WP_015924740.1"
                     /translation="MKKVCKILVLLLIFTTLFSFVCYADNPIVQTYYTADPASMIYNDT
                     CYLYVTHDEDTTVNNFYTMNEWRCYSTTDMVNWKDCGSVLSYKTFSWAKGDAWAAQCIP
                     RNGKFYLYVTLTNQYGARTVGVAVSDSPTGPFKDALGKPLIANNGAQDIDPTVFIDNDG
                     QAYLYWGNGNAYYVKLNQDMISYSGSIVQVNPKPSGYIEGPWLYKRNNVYYLVYAGMGS
                     NGENIQYATSNSPTGPWTSKGAIMNSKNSFTIHPAITDFKGKSYFFYHTGDLPGGGSYK
                     RSVCVEEFKYNSDGTIPTIPITKTGPAQVQYLDPFVKNEAETICWESGVETEICSEGGM
                     NVGFIENGDYIKVKGVDFGSGASSFVARVASETSGGNIELRLDSPTGKLVGTCSVSETG
                     GWQTWSDKSCTVSGAEGVHDLYLKFTGGSGYLFNFNWWKFEKSGTPTIVGDLNGDDCVD
                     AADYALMKKYILGLINDFPVDNDIEAGDLNKDGTIDALDCAVFKKLLLGII"
     gene            12179..15046
                     /locus_tag="CCEL_RS06195"
                     /old_locus_tag="Ccel_1236"
     CDS             12179..15046
                     /locus_tag="CCEL_RS06195"
                     /old_locus_tag="Ccel_1236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014312556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH146|CBM22"
                     /protein_id="WP_015924741.1"
                     /translation="MLKTMSILLPCLLIFSLIFSVQIPLSASAANVELLKQFDMEQVKI
                     TDTYYVNALNKEVAYLQAIDPNRLLVGFKKTAGLSTTYSYYGGWENNTLIQGHTMGHYM
                     SALAQAYKNTKSDPTVNADLKSRIDLIISELQACQNKNGNGYLFATPATQFDVVEGKAS
                     GSSWVPWYTMHKIMSGLLDIYKFGGNQTALTIATNLGNWIYKRVNAWDSATQSRVLGVE
                     YGGMNDCLYELYKLTGNGNHLTAAHKFDENSLFNTIAAGTNVLPGKHANTTIPKFIGAL
                     NRYSTLGTSESSYLKAAQQFWAIVLKDHTYVTGGNSEDERFRDAGKLDAYRDNVNNETC
                     NVNNMLKLTKELFKATGDVKYADYYENALINEIMASQNPETGMATYFKAMGTGYFKVFS
                     SQFNHFWCCTGTGMENFTKLNDSLYYNNGSDLYVNMYLSSTLNWSEKGLSLTQQANLPL
                     SDKVTFTINSASSSEVKIKFRSPAWIAAGQNITVKVNGTPINVDKANGYLDVSRVWQTG
                     DTVELTLPTEVRVSRLTDSPNTVAFTYGPVVLSAGLGTESMTTQSHGVQVLKATKNVTI
                     KETININTAASPSIDNWLANIKNNLVQTPGKLEFTLKNTDEDNHLVFTPHYQRYKDRYG
                     IYFKLGTYEGKQPTDNLLDNPDIESGNTTGWTVNGAGTIASSTVQKHSGSYSLLHTGRT
                     GAWNGPIQNITTKVQNGNTYTCSGWVILDNTASAPITMTIRKTDDNGTSYVNIATATGS
                     NSSWVQLSGNYTLNVTGALTDLSIYFEGPDSGTNFYVDDALVKVYGKTTFYQNTSFGGT
                     AVSLNPGSYTTAQLTAAGISDNWASSIKIPEGYTVEIYDDDNFTGTKWSFSADNSNFIE
                     AGCNDKMSSVKIFPTLSQVKYGDINRDGTVDTIDFALLKQFLLGAQVTIDSVAADLDGD
                     ESVTAMDFAVFKKYLLGQITELPAF"
     gene            15155..16969
                     /locus_tag="CCEL_RS06200"
                     /old_locus_tag="Ccel_1237"
     CDS             15155..16969
                     /locus_tag="CCEL_RS06200"
                     /old_locus_tag="Ccel_1237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004616906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH27|CBM6"
                     /protein_id="WP_015924742.1"
                     /translation="MKKVRTVSTIIFLGLMITVIMVLNTGAWDNGLAKTPPMGWNSWNI
                     FHGDINETKIKQIADTMVSSGMKEAGYVYLNLDDNWMANPARDSNGNLRADPTRFPSGI
                     RALADYVHAKGLKLGIYGCRGTMTCMNIPQSGSKGYEDKDAKTFASWGIDYLKYDNCNI
                     PNGSDMKTDYQKMQTALANCGRPIVFSICAWGYQSWMPATGNLWRTTGDIADKWDNGNE
                     WFKGIINAIDGNAQYTSSAAPGAWNDPDMLEIGNGGCTTEEYRTQMSMWSMMASPLIAG
                     NDIRTMSQTTKDILLNKEVIAIDQDPAGVQGKRVKSANGLEIWVKPLGTNGTTKAVALL
                     NRNSATSNITVNWSDIGVSGSVTVRDLWAKSDKGSFTGSYTASVPSHGTVLIKISTEPP
                     APVDATKQIEAESYSNQSGIQTETCSEGGEDVGFIENGDYTVYSNVDFGDGVGGFQARV
                     ASATSGGNIEIRLDSPAGTLIGTCPVAGTGDWQTYTDVKCTVSGATGKHDVYLVFKGDS
                     GYLFNLNWFTFTPGSVNTGTLGDLNSDGQVDAIDLQLLKKYILGLGAIENTKLADLDAN
                     GDINAIDFSLLKQFLLGIRTSFPGQGAA"
     gene            16999..20367
                     /locus_tag="CCEL_RS06205"
                     /old_locus_tag="Ccel_1238"
     CDS             16999..20367
                     /locus_tag="CCEL_RS06205"
                     /old_locus_tag="Ccel_1238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004616907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH59|CBM6"
                     /protein_id="WP_015924743.1"
                     /translation="MKRKILSVLLLVTMTTALFSATPMNTASAASTDFVLDGNNIKAGN
                     INGLTFKGFGVLSGNSSSALLMDYKSEHPEKYTELLQILFGGKNPIMTHVKIEMGNDRN
                     NSTGPDPSTMRWENETANVKRHPGFQLAADAKKVNPNLKVSILRWNAPGWANSNDKIYT
                     WYKNTILAAYRQYGYMIDYVNPGVNEQTPNLTWTKQYAQRIKTDSTGFNNAEERALYNN
                     IKVVISDEVSVGSFGDDMVSDSTLRDAVSVAAYHYNTDDNSLGSFKQLAESFDKEVWNS
                     EAQATFSNSSFRPNNNMKDPTVAGTGIGGTNGPLEMGNTVIKGFVNSRRTHFIYQPVIG
                     SFYEGGQYSFKELVSARDPWSGWIHYDAGLVILRHFSWFSKAGWENESNTAGVWRAVPQ
                     ASFTGATGTNPVNGRNGTPSYMTLASPDKHDFSTIFINDSEYSKTYTFKTINMAYSGNP
                     SLEVWETRAADKGASFNSNYMKYTGTVSTNSSGVYTVNVKPYSIVTVTTLSNSGKAEFN
                     TPLPVEGDRPVLDTDKTGSMQDTRDNILYADNFDYSSKTAPVIAEGGQITGTQSYIDSR
                     GGSKSAIPRYASDRNGAFEVYLPDGSSNYILRQQVNQSSMGLGGTWNNGNPITGIGDNR
                     WMNYKASVDVSFEHNSTEGGNNYAAIGARQQGGENSHYLNGTPYILKFWFDGGWSLLVN
                     GSSVANGNVASGSGGVKISGFNTAYNAWHNISIMVADNKVTAYLDNTILYTYTDTTQRL
                     SGRIDLASGYYNTCFDNLKVETIDGYAPYYSEMLDNLEMYDLSSVSATKLVYGGSWAHE
                     NGKSMYNYQRSLSTSQGIGATIQYSFTGTGLDILGANNGSAKLEVTVDGRVVNSSVGTM
                     VSGNLHQNFTLHGLEYGKHTVCLKVLSGTMVVDAVGVVANIAGASEIPVEQSAYSRIEA
                     ESYSNQSGIQTETCSEGGEDVGFVENGDYTVYNNVDFGDGVGGFQARVASATSGGNIEI
                     RLDSSTGTLIGTCPVAGTGDWQTYTDAKCTVSGVTGKHDVYLVFKGDSGYLFNLNWFTF
                     SEKTVIGNLGDINSDGQVDAIDLQVLKKYLLQLGEIGDTKLADLDANGEINAIDFSLLK
                     QFLLGTIISFPGEAL"
     gene            20431..23478
                     /locus_tag="CCEL_RS06210"
                     /old_locus_tag="Ccel_1239"
     CDS             20431..23478
                     /locus_tag="CCEL_RS06210"
                     /old_locus_tag="Ccel_1239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014312558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH2|CBM6"
                     /protein_id="WP_015924744.1"
                     /translation="MLRKKILCIFLVTVLMLTILPIPQQTVMADTGVLKELKGTDIYNG
                     LRGLNFNEGWKFNKGDVSNGQSTGYNDSGWSGVTLPHDWSIYNTFNKSSAAGAGGGYLD
                     GGIGWYRKTFTVPSDYTGKKVFIEFDGAYMNSQVWINGTLLGTRPYGYSSFEYDLTPYL
                     NIGGSNVIAVRLNNNQPTSRWYSGSGIYRNVWLTVLDPVHVTYCGMFVTTPTVSSSSAT
                     ANVSTKVLNQGSTAKSVSLKTTITDAEGNVVATNTSSVASIAGSGSNTFSQNLTVSNPH
                     LWSPASPYLYAVQTQVIVDGNVTDTYSSTLGIRYFSFSSTSGFSLNGVNMKINGVCLHH
                     DLGSLGAAVNYRAIERELQIMKDMGCNAIRTSHNPPDPQMLEICDRLGLMVMDEAFDCW
                     ETGKNSNDYHLYFNNWAQTDLQAMVTRDRNHPSIIMYSIGNEIPSPSVATATKLKNWVK
                     DVDNTRPVTLGTFAVSMGDATPQAVASVLDLVGYNYFPYMYDGGHNNHPEWKMFGSETS
                     SAVRSRGVYKTPTNKNILTDSDNQCSSYDNSVVSWGNSAESSYNEINKRNYMAGEFIWT
                     GFDYIGEPTPYEWPAKSSYFGIVDTCGFPKDIYYFYQSKWSTKPMVHILPHWNWSTGTN
                     VEVWAYSNCDTVELFLNGKSLGSKSVGTAGHLSWSVPWSSGTLRAKGTKGGTVVYDEVV
                     TAGTPSKVLLKPDRTSVKADGKDLIYIETDIADGNNVTVPTADNTVNFSISGPGVIVGV
                     DNGNPISTEAYKGSSRKAFNGKCLVIVQPTKVNGTIVVTASSNGLSSGSVSIASTGGAE
                     APIVSAYKKIEAENYDNQSGIQTEACSEGGQDVGFIENGDYTVYNNVDFGSGAESFTAR
                     AASATSGGNIEIRLDSPNGTLIGTCPVAGTGDWQTYADVNCSVSEVSGKHDLYLKFTGD
                     SGYLFNINWFTFTARNSAKLGDLNSDDQIDAMDFQLMKKYLLGLGEIKDTKLADLDASG
                     TIDVLDLMLLKQYLLGTITSFPGQGT"
ORIGIN
        1 gtgtttaaaa aaattaaaaa gttttcagtt tttatggtag ctcttttatt tttgtctgtt
       61 tatagtttta acttagtatt tgcagactat cccatatttt accagaggta tacggccgat
      121 ccttcaggtt tagaagccaa tgggagactt tatctgtatt cttctcatga tgtatatgac
      181 cctaacaaac cgggttatat aatgaatgac attacatgta tatctaccga tgacttgaag
      241 aattggacag accatggaga ggtttttaaa gcttctggct gggcatcatt atcttgggca
      301 ccggtagttg ttgcaaaaaa caataaatat tatatgtatt ttggaaacgg tgctggaggt
      361 ataggtgttt cggtaagcga cagtcctaca ggtcctttca aggatgcact gggaaaagct
      421 ttgataaatg ggagcacacc cggggtaaat ccccccagcg gattttggtg ctttgatccg
      481 ggagcctttg tggacgataa cggtcaggca tatttgtatt tcggaggaaa cggggaaggt
      541 aatacacgcg ttataaagct caacagcgac atgataagtc ttaatggttc tgcatctggt
      601 attacagctc caatcttttt tgaggattcg tggatacaca agtataacgg caagtactat
      661 tattcctatt caacaaattt ctcaaagggt gctgctacca tagattatat gatgagcgac
      721 aatccaataa ccggatttca gtacaagggc accgttctgg caaatccccc tttaaacgaa
      781 ggcaacaata atcaccatac tatatttcca ttcaaagggg attggtatat tgcttatcac
      841 aacagggctc ttgcaatagc caatggtgct gccagcggtg atgcacggac gtatcaaaga
      901 agtgtatgta tagataaact caattacaat gcagatggaa ccatgcagaa ggttacaatt
      961 acgacagatg gtcttaaaca gcttaagtat gtaaatcctt atgtaacaaa cgaggccgaa
     1021 accatggcac agggaagcgg gatcaacacg gaagaatgta ccgaaggagg ccgtgatgtt
     1081 gcctttattg aaaacggaga ctggatcaag gtgagaggtg ttgattttgg tactgctgga
     1141 gcagcctcct ttgacgcaag ggtagcatca tcaaccagcg gaggaaatat tgaaatccgt
     1201 ctcgacagcc ttacaggaaa gcttgtaggg acttgtgttg ttgagaatac aagtggttgg
     1261 cagaattgga ctacaaagac ctgttctgta agcggtacta caggtgtcca cgatctgtac
     1321 ctgaagttta ccggcgacag cgggtatctg tttaatctaa actcatggag attcaatact
     1381 tcaggagcaa aaacagtata tggcgatctt gatggcagcg gtgatattaa tgctattgac
     1441 ttctcactta tgaagcaata tctgcttggt tcaataacca aatttcctat agaagatggg
     1501 ataattgctg cggatttgga tgccagcggt acaattgatg cgatcgacta tgtacttctc
     1561 aaagaatatt tacttggtaa gaggacccaa tttcctgctg aattataaca aagaaaatag
     1621 attttcttta ccgatgaaaa tcagcaacag aaattaggcc gaaaaaaacg catttagtta
     1681 aaaaaacaaa aatttaaacg gaggttaata agtatgttaa gtaagagaaa aacccggaaa
     1741 ttcagaatat tcagtacctt gtttgtagca cttttgtgtg caacgataat tactagcagt
     1801 tttccactga cagcagatgc tgcaatggcc acaggaaagg ctaaatttgt tggaaatata
     1861 tggtatgatg gtaatgcacc aagtaagtat gcagactact ggaaccagat aacacctgaa
     1921 aatgctacca agtggggtcc ctgtgaacca cagcagggtg tatacaattt cagccaggct
     1981 aaagcaatgt acaattactg taaaacaaac aagattcctt ttaaattcca tacacttata
     2041 tggggttcac aatatccaaa ctggttaaat aatctttccg gtacagcaag aaaaacagcc
     2101 atcgaaaact ggtacaaagc ggctgcacag aacttcccgg atgcagaata cattgatgtt
     2161 gttaatgaag ctatgcctgg acatgctcca ttcccattta aaaatgatat cggtggtgac
     2221 aatggcctct atggtacagg atgggattgg atagtatggt cctttgaaat ggctcgcaaa
     2281 tactttccaa attccaagct gctgattaat gactataatg ttttgaatga gtggtcttgc
     2341 ctcgatcaat acataccggt tgtaaaaata ttgaaggcca gaaacctgat tgatggtgtc
     2401 ggctgccaat cacacggcct tgaaaagaca agtgctgcga atctaaagtc aagactggac
     2461 agacttgccg caacaggagt acctatatat atttctgaat tagatttaga tattgcagat
     2521 gataacacac agaaaaacaa gatgcaggag cttttccctg taatgtatga acattctgca
     2581 gtaaaaggta ttactatttg gggatattta caaggacgta catggattcc aaattctcac
     2641 cttctacgca gcgatggatc tgaaagacct gcaatgactt ggttaaagca atatatggca
     2701 aaagttccag gtgaagatgt acctgtagaa acaagaagtg cattttcaaa attggaagct
     2761 gaaagctata acgaccaatc cggaatacag aacgttacat gttacgaagg aacagaggct
     2821 gtgggatata ccgaaaacgg agattataca gtttacaaga atattgattt ctcaaacggt
     2881 gctaccagct tccaagcaag agtatcaagt gcaacaaccg gaggtaacat cgaaatcaga
     2941 cttgacagtg ctacgggcac attgatagga acttgtccgg ttgccggaac aggcgattgg
     3001 cagaaatttt tggatgctaa gtgtactgtc agcggtgtaa gcggaaagca cgacttatat
     3061 ctgaaattca caggcggcag cggttactta attaatctta attggttcat gtttagcaac
     3121 actcctgttt ctacagacaa aataggcgat ttaaattcag acggacaaat agatgcacta
     3181 gacttccaag tcttgaaaaa gtgtatttta ggcacaggaa caattgaaaa tacaaaactt
     3241 gcagacttgg atgccaacgg tacaatcgat gccttggatt ttgtacttat gaaacaatac
     3301 cttcttggac aaataacaaa atttcctgct gacaaataat tattaattgg aaaaggggta
     3361 tttaataccc tttttctaaa ataatacgat tttaaagagg taaaaaatga aaaaagtaag
     3421 caaaattgca gctctcttat tagtacttac tttgtttatt ccaacagtag gctatgcaga
     3481 caatccaata gtgcagactt tatatactgc tgaccctgcc cctatgatat ataacgatac
     3541 atgctacgtg tacacgggac atgacgagga tacactggta aatgatttct ttactatgaa
     3601 tgactggaga tgttactcct caactgatat ggtgaattgg acagataacg gttcgccact
     3661 gtcatactct tcgttcagtt gggcaaaagg ggatgcatgg gcaggccaat gtattcaaag
     3721 aaatggaaag ttttattatt atgttccttt gaccccgaaa accggaggga cggcaatcgg
     3781 tgttgcagta tcagatagcc ctacaggccc atttaaagat ccccttggaa aaccattagt
     3841 tagtactggc agcggcgaca ttgacccgac agtatatatc gatgatgacg gacaggctta
     3901 tctgtactgg ggcaatccaa acctttacta tgtaaagttg aatcaggata tggtttccta
     3961 ctcaggcagt attgtaaagg tacctttgac aactgcaagt ttcggaacaa gaagtaaaac
     4021 cgacagacca actacatacg aggagggacc atggttttac aagcgtaaca gtttgtacta
     4081 tatggtattt gcaggcggcc ccatatcaga gcatataggt tattccacca gtaccgggcc
     4141 tacagggcct tggacttatc gtggtaaaat catgcctacc cagggcagca gctttacaaa
     4201 tcatccgggg gtagccgatt ttaaaggtaa ttcctatttc ttctatcaca atggtgcttt
     4261 gcagggtgga ggagggtttc accgttcggt gtgtgtagaa caatttaaat ataatgctga
     4321 cggtactttt ccaaccataa atatgactac aaccggctct acccaaatcg gcaatcttaa
     4381 tccatttatt aaaactgagg cggaaacaat ctgctgggaa tcaggtattg aaacggaaaa
     4441 gtgcagtgaa ggcggaatga atgtagcctt tatagaaaat ggggactata taaaggtaaa
     4501 aggtgttgat tttggtacgg gtgcagcagc ctttactgcc agagttgctt ctgcaaccga
     4561 cggcgggaat ctagaacttc ggcttgacag cccaacaggt aaacttgtgg ggacttgtgc
     4621 agttacaagc acaggaggat ggcagacatg ggtcgataag acctgtacgg taagcggtgc
     4681 cgaggggata catgacttgt acctgaaatt tacaggtgga agcggttatc tgttcaattt
     4741 taactggtgg aagtttatca aagctgggaa tacctctgtt attggagatc tcaatggaga
     4801 caaaagcgtg gatgcggcag attatgccat gatgaagaaa tatcttttgg gattaattga
     4861 agattttccg gcagaaaacg atattgaagc cggagactta aataaagaca gcgtcattga
     4921 cgcacttgat tttgcagttt ttaaaaaata tctgcttggt acaattccaa gtttaccatg
     4981 attaaatgaa aggggttaaa taaatgataa aaaatatatt aactaaaaaa acgatttggg
     5041 gaatggtggc atttgttttt gctttaactc tagtttttac agtgcctgat tccaaggtgc
     5101 aggctgcagc actgcctacc acaccaccga caggctatga ccgagtccag agtaacattc
     5161 cgcacggtca ggttagctat attaattacc aatctaaggc aacaaacagt caaagaagag
     5221 caaggattta cctgcctcca aattattcag cagacaaaaa atacagtgta atgtatttac
     5281 tgcatggtat cggtggaaat gaagacgagt ggtacaataa cggtgcacct aacgttattc
     5341 ttgacaatct tatagctgca ggtaaaattc agccatttat cgttgtatta ccaaatggca
     5401 atgcaacagg aactggtgta tctgatggtt ggactaattt tacaaaagat ttaatcgaaa
     5461 gtcttatccc atatatagaa tcaaactact ccgtttatac ggatcgtaat cacaggactg
     5521 tttgcggtct ctcaatgggt ggcggacaat ctttcaatat cggacttcct aacttgaacc
     5581 tgttcccata tgttggagca ttttcaccgg cacctaatac actccctaat tcccaacttt
     5641 tccctaatga cggagcctca gctaagcagc tgttgaaatt cttgtttatt tcttacggaa
     5701 ctaccgacag tctgattagt tttggtacag gagtacataa ttactgtgat tcccagagta
     5761 ttccaaatac ttacttcctt attcagggtg caggtcatga ttggaacgta tggaagcaga
     5821 gcctttggaa ttattctcaa atgatatgtg aaaagggttt tacagactat ggccctgttg
     5881 cacctgtatc agcatttaca caaattgagg cagaaagttt caccagtcag tccggcgttc
     5941 agacagaaac ctgtactgaa ggaggtctga atgtagggta tattgagaat ggtgattatg
     6001 tagtttataa caatgtagac tttggcagtg gtgcaacaag ctttcaggca agagtagcaa
     6061 gtgctgggaa tggaggtaat atcgaaatca gattggatag tataacaggt ccgttggtag
     6121 gaacttgtgc agttaaaggc acaggcgatt ggcagacttg gactgatgca aagtgtactg
     6181 taagcggagt aaccggaaaa catgacttgt atctgaaatt tacaggtgga agcgattatc
     6241 tgatgaattt taactggttc aaatttggta atgcgacaca gactcttaca ggtgatctta
     6301 atggagatgc cagtgaagat gcaacagact atgccttgct gaaaaagtat cttcttggtc
     6361 agattaatga cttccctgtc gaagacgaca ttaatgctgg agatatgaat aaggacggtg
     6421 taattgacgc tctcgacttt gctgtcttta agaaaatcct tttgggcaca atctaatcta
     6481 ggttagcagg taaattttta aatttacctg ctctccttgt aacaaaaata attaaaagga
     6541 ggaaccatgt gatgcaattt aaaaaggtct tcagtatttt attgctggta tgtctattgg
     6601 ttacacaaac gactatagtc ggtgcatggc agtctgataa tgacaacggt acctacacaa
     6661 acccgatttt aaacgctgat tatcctgata tttatgctat cagggtggga agtgattact
     6721 atatggtcag ctccactttc gtatcatttc catcaatacc tatccttcat tcaaaggatt
     6781 taattaactg ggaaattata ggatatgttt cttcggatct taacggtaca ggaaaatctt
     6841 ataatctgac taatacattt gacgattacg gacatggctg ttgggcacca agcattgcct
     6901 accgtaacgg tacatattat gtgggaatat atcaggcaca ggggaagttc atcatgtgta
     6961 ccgccacaaa tccggccggc ccttatacaa aaacggtata caatcaagga tttcatgacc
     7021 cggcactttt tattgatgac gacggtacag gatatatcgt ctctgaagca aacgatgtaa
     7081 aggttacgaa gctaagtgct gattataagt cggtagtgaa cagtcaggtg actacccgta
     7141 ttgagggtgc aacaggaaat tacctggttg aaggcacaca tgttatgaaa aagaacggat
     7201 attattacat attccgtaat tcaactcctc cagaatcata tacgtactgc ctcaggtcaa
     7261 agagtatata tggcccttat gaaatgagga tactactgaa cggtccaagc atttccggcg
     7321 gaagtcagat tcaccagggg ggacctatag atactacaac tggtgagtgg tggttctatg
     7381 tatttcagga tggacaggga ttgggccgca gagacatttt gatacctatg cagtggcaga
     7441 atgactggcc gattctcgga gacccttcta cagtaaaaaa tgtaagcata gcaggaaaaa
     7501 cctatcctat gggtaccgta ccggttacat ataaaaaacc ggatgtaggt gcaacatacc
     7561 caatccttac aattccgaat tctgatgaat tcagttcaac aacaatggga gtacagtggc
     7621 agtggaatca ttaccctgac aatacaaagt ggtctttaag cgagcgaccg ggctatctca
     7681 gacttcacgc taaaaatgca aataatctgt ggagggccac taacactctt acacaaagag
     7741 tggaagggcc ggattgccag ggtacaatag agcttgacac taccaatatg ttagatgggg
     7801 ataatgctgg actatgcctg cttaatattc cgtatggaac catcggggta agcaaatccg
     7861 gcggagtaaa aaggatagtt gccaatatca acgctaaaaa ggatacggca ggaacaatta
     7921 caaatggtcc tacacttacc ggaaatactg tctatttaag ggctaaagca gatcttatca
     7981 gtaataaggc aacttttttc tatagcacgg ataatgtgaa cttcactcag cttggaggaa
     8041 cattaagtat gccctttgac ttgggatttt ttcaggggga caagttcggt atattcaatt
     8101 atacaactgc ttcctcggga ggttatgcag atattaactg gttccgatat tatacttctg
     8161 cggggccaaa tactcctatt cctgacatta cgttatctgc ctttgaaaaa atagaagcag
     8221 aaagctacaa ctcccaatcg ggaatccaga atgtaacttg tgatgaagga accgaggctg
     8281 taggctatac cgaaaacggc gattacgttg tatataagaa tgttgatttc ggaagcggag
     8341 caaatggttt taacgccaga gtatcaagtg caacggttgg aggtacgatt gaaatcaggc
     8401 tcgacagtgc caatggtaca ttaataggtt cttgccctgt tgcgggaacg ggagggtggc
     8461 aagcttttac agatgcaaat tgtaccgtaa gtggtgtaag tggtaaacat gacctatatt
     8521 tgaaatttac aggtgaaagc ggatatctgt ttaacatcaa ctggtttaaa ttcagtaata
     8581 catctgttat ttcagataaa ttaggtgatg ttaattctga cggacagatt gatgccattg
     8641 acttacagct cattaaaaaa tatatcctgg gattgggaga aatcgagaac ataaaaactg
     8701 ctgacctgga tggaaacggc gatgtaaatg caattgattt ttcccttatg aaacagtact
     8761 tactggggct aattaccgag tttccagggt gaaactcggt aataacccac gcatctcaac
     8821 cgtatcccaa taaataaaat ttaactaagt ttattaagaa aggaagggaa aaaatatgaa
     8881 tatatttaaa aaaggttttt caattttttt aggcttgttc atgataatat catcattcgg
     8941 ttccatggtt aacgctgcag caaacccaaa tccgtcatgg aacgttgacg agagggttat
     9001 atttcacaat cagtgcagcc catatgatta ctatgcggct aaagacccta ctatcgttta
     9061 ttataacggt aaataccttg tttattacac aggtgcaaat aaaagcggcg gttggcaaat
     9121 gtgttttacc tcagctagca caatttccgg tctgaaaaca gctccacgta cctatatgag
     9181 taaaatagga gaaagctatt tctgtgcacc tgaattgttc tactatgaac cgcagaaatt
     9241 atggtacctt gtttaccagg atggtacgca cggggcagct tatgcaacta caacaactcc
     9301 tgatgatccg aattcatggt ccgggccaaa atcctttggt atatccggca acatgggatg
     9361 ggattattat ataatatgcg atgatcagta cgcttatatg tacaatacac caagtgatgg
     9421 atcaggaaaa ctctatatga gaaaaaccac tctggcaaac ttccctaata agggctggag
     9481 cacacctact gttgcatgct caaatgtttt tgagggagcg gcggtctata agagtcttgc
     9541 cgatggtcag tactatatgc ttattgaagc aatgatagat ggcagaagct acgagttgtt
     9601 tacatcctcc agtgcaggag gcccttggac tctggtcaat aataaatggg caacaaggag
     9661 caatcttaca aaatataatg cggacaagtg gacaactaac gtatcacatg gtgaacttat
     9721 acgtgcagga tataatcaga aactagaaat aaatgatata aacaaggtgg atttccttat
     9781 tcagggtact accaatatga acgctgaata tcagcaaatt atatgggatt tgggccttat
     9841 cagaaattat accggaagcc ccgatacgcc tgttacacca agaactgctt ttgaaaaaat
     9901 agaagctgag agctggaatg accagtctgg aatccagaat gtaacctgcg atgaaggtac
     9961 cgaggctgtg ggttataccg aaaacggaga ttacagcgta tacaagagca tagatttcgg
    10021 aagtggtgct accagcttcc aggcaagagt atcaagtgcc accagcggag gcaagattga
    10081 aataagactt gacagtgcaa ctggtacctt ggttggaact tgcacagtta gcggaacagg
    10141 cagctggcag accttcgcgg atgtgaactg tactgtaagc ggtgtaagcg gcaaacatga
    10201 cttatacctg aaatatatag gagacagcgg atacttaatc aatcttaact ggtttaaatt
    10261 cagcaacaca cctgttgttt cagataaatt gggtgatgta aattctgatg ggcaaataga
    10321 tgccatagat ttacaattat tgaaaaaata tcttttagga tccggaacaa tagaaaatac
    10381 aaagcttggt gatttgaatg ctagcggaga tgttgacgca atcgattttt cactgctcaa
    10441 acaatacctt cttgggcaga taacaaaatt ccctgctcag gcgtgatatt ggagtcggta
    10501 aagcttcttc gatatcattt tatggatagt caaaattgat tttaggaaag aggtattttt
    10561 atgaaaaaag tttgcaagat attagtactt ttacttattt ttactacgct tttttcattc
    10621 gtatgttatg cggataaccc gattgtgcag acgtattaca ctgctgatcc ggcatcgatg
    10681 atttataacg acacttgtta cctgtatgtc acacatgacg aggatacgac tgtaaataac
    10741 ttttatacca tgaacgaatg gagatgctat tcaacaacag atatggtaaa ttggaaagat
    10801 tgcggttcag tactgtctta caaaacattc agctgggcaa aaggagatgc atgggcagca
    10861 cagtgtatac ctagaaatgg aaagttctat ttatatgtta cacttactaa ccaatatggt
    10921 gcgagaacag taggtgttgc agtgtcagac agccctacag gaccatttaa agacgctctt
    10981 gggaagcctt taattgcaaa taacggggca caggatattg atcctaccgt atttatcgat
    11041 aatgacgggc aagcctactt gtattgggga aatggcaatg catactatgt gaaattaaat
    11101 caggatatga tttcctactc aggaagcata gtacaagtaa acccaaagcc gtcagggtat
    11161 atagagggtc catggcttta taaacgaaac aatgtatact atttggtata tgcaggtatg
    11221 ggttcaaatg gcgaaaatat acaatatgct acaagcaaca gtcctacagg cccatggact
    11281 tcaaagggtg ctattatgaa ctcaaaaaac agcttcacaa ttcatcctgc cataaccgac
    11341 tttaaaggaa aatcatactt tttctatcat acaggtgatt tgccgggagg aggcagctac
    11401 aaacgttcag tttgtgtaga agagtttaaa tacaattctg acggtacgat accaactatc
    11461 cctataacta aaaccggccc tgctcaggtt caataccttg atccatttgt taaaaacgag
    11521 gctgaaacaa tctgctggga gtccggagtt gaaacagaaa tatgcagtga aggcggaatg
    11581 aatgtaggct ttatcgaaaa cggggattat ataaaggtaa aaggtgtaga ttttggctcg
    11641 ggagcatcat catttgttgc cagggttgct tcagaaacaa gcggcgggaa tatagaacta
    11701 cgacttgaca gtcctacagg caaactggtt ggaacttgtt cagtaagcga aacgggcgga
    11761 tggcagacct ggagtgataa gtcctgtaca gtaagcggtg ctgagggagt acatgactta
    11821 tatctgaaat tcaccggagg aagcggttac ctgtttaatt tcaattggtg gaagttcgaa
    11881 aaaagcggaa cacctacaat tgttggagac ctcaatgggg atgactgtgt agatgctgca
    11941 gattatgcat tgatgaagaa atatattctg ggattaatta atgattttcc tgtagataac
    12001 gacattgaag caggagattt aaataaggac ggaactattg atgcactaga ttgtgccgtt
    12061 ttcaagaaac ttctgttagg tattatttaa aaattacccg ggtagaacta tggtatttta
    12121 gtccatatat ggtttaaatt gttatatctg aatttgtaaa ttggttaagg aggcaaacat
    12181 gttaaaaact atgagtatac ttctaccatg cttattgata ttttcactta tattcagtgt
    12241 acaaatacct ttatcagctt cagcagcaaa tgttgaactc ctaaagcagt tcgacatgga
    12301 acaggtaaaa ataacagata catattatgt aaatgcactt aataaagagg ttgcctactt
    12361 gcaggcaatt gatccaaacc gtttgttggt gggttttaag aaaacagctg gcttatcaac
    12421 aacttatagc tattatggag ggtgggaaaa caataccctg attcaaggcc ataccatggg
    12481 acattacatg tcggcacttg ctcaggctta taaaaacact aagtccgacc cgacagtaaa
    12541 tgcagatttg aaaagccgta tcgatttgat tatatccgaa ttgcaggctt gtcagaataa
    12601 aaacggcaat ggatatttgt ttgcaactcc ggctacccaa tttgatgttg ttgaaggaaa
    12661 ggcgtccggt tcaagctggg taccgtggta taccatgcac aaaatcatgt ccggtcttct
    12721 tgacatttat aaatttggag gcaaccaaac cgcattgaca atagcaacca acttgggaaa
    12781 ttggatttac aaaagagtaa acgcttggga ttctgcaaca cagtcaaggg tattgggtgt
    12841 tgagtatgga ggaatgaatg actgtctcta tgaattgtat aagctgactg gtaatggcaa
    12901 ccatttaaca gcagcacata aatttgacga aaattcacta tttaacacca tcgctgcagg
    12961 cacaaacgtt ttacccggaa aacatgccaa tacaactatc ccgaaattca tcggtgcttt
    13021 gaatcgctac agcactctag gaacatcaga atcatcatac ttaaaagcgg cacagcagtt
    13081 ctgggccata gttttgaaag accatacata tgtaacaggg ggcaacagcg aagatgagcg
    13141 tttcagggac gctggcaaac tggatgcata cagggataat gtaaataatg aaacttgtaa
    13201 tgtaaataat atgctgaagc tgactaaaga gctgttcaag gcaacgggcg acgttaaata
    13261 tgcagattac tatgagaatg cattgataaa cgaaatcatg gcttcacaga atccggaaac
    13321 cgggatggct acgtacttca aggctatggg aactggatat ttcaaggtat tcagttccca
    13381 attcaatcat ttctggtgct gtacgggaac gggaatggag aatttcacaa agctgaatga
    13441 cagcctgtat tataataatg gttccgacct gtatgtaaac atgtatctga gttctaccct
    13501 gaactggagc gaaaagggtc tttcactgac acagcaggcc aatctgccat tatcagataa
    13561 agtaaccttt actatcaaca gtgcttcttc atcagaagtg aaaattaaat tcaggtcacc
    13621 agcatggatt gctgcaggac aaaatattac ggtcaaagtt aacggtactc caattaatgt
    13681 tgacaaggcg aatggctatc ttgacgtcag cagagtgtgg cagacaggag atacggttga
    13741 gttgaccctg cccaccgaag taagggtatc cagactgact gacagcccca atacggtagc
    13801 ctttacatat ggtcccgtag tattgagtgc aggtcttgga actgaaagca tgacaactca
    13861 atcacacggg gtccaggttt taaaagcaac gaaaaatgtg actatcaaag agactattaa
    13921 tattaatacc gccgccagtc ccagcattga caattggctt gccaatataa agaacaattt
    13981 ggttcaaacg cctgggaagc tggaatttac attgaaaaat accgacgagg ataaccattt
    14041 ggtattcaca cctcattatc aaagatacaa ggacaggtat ggtatctact tcaagctggg
    14101 aacgtatgag ggtaaacaac ccacggataa tttgcttgac aatccggata ttgagtcagg
    14161 gaacaccaca ggatggactg tgaatggtgc gggtacaatt gcctcttcaa cagtacaaaa
    14221 gcactcggga agctatagtc tgctgcatac aggcaggaca ggagcctgga acgggcctat
    14281 tcagaacatt acaacaaaag ttcagaatgg taacacgtat acttgttccg gctgggtaat
    14341 actggacaac actgccagtg ccccgataac aatgactatc agaaaaacgg atgacaacgg
    14401 aacttcctat gtcaatattg ccactgctac cggaagcaat agttcctggg ttcaattgtc
    14461 aggtaactat accttaaatg ttacaggtgc attgactgac ctgagtatat attttgaagg
    14521 accggacagc ggcaccaatt tttatgtgga tgatgcctta gttaaggttt atggcaaaac
    14581 taccttctat cagaatactt cttttggcgg tactgcggtg tcgctgaatc caggcagcta
    14641 tactactgct cagctcactg ctgcaggtat ttctgataac tgggcatcat caatcaaaat
    14701 acctgaaggc tatacggttg agatttatga tgatgacaat ttcactggta caaagtggtc
    14761 ttttagtgca gataattcga actttataga agccggatgc aatgacaaaa tgtcttccgt
    14821 gaaaattttc cccactctga gtcaagtgaa gtatggggat attaacaggg acggtactgt
    14881 agatactatt gactttgcac ttttaaagca gtttttgttg ggtgctcagg tcacaattga
    14941 ttcggtagcg gctgatttgg acggcgatga atctgtgacg gcaatggatt ttgcggtatt
    15001 taagaagtat ctgctgggac aaataacaga gttgcctgct ttttgatgtt ccgatggaat
    15061 tatttgattc caaatttatt gatatagcaa atcagccgat tcgttctggt tttagaacag
    15121 tctaaataac gaaaatttag gggggataaa tagaatgaaa aaagttcgta cagtcagtac
    15181 aattatcttt ttaggactta tgattaccgt aattatggtt ttgaatactg gtgcatggga
    15241 taacggtctt gcaaaaacac caccgatggg atggaacagt tggaacatat tccatggaga
    15301 cattaatgaa actaaaatca aacagattgc tgataccatg gtaagctcgg gtatgaagga
    15361 agctggctat gtatacctga atctggatga taactggatg gcaaatcctg caagagattc
    15421 caatgggaac ttgcgggccg atcctacacg attcccaagt gggattaggg ctttagctga
    15481 ttatgtacat gcaaaaggtc tcaaactagg gatatacgga tgtcgtggaa caatgacctg
    15541 tatgaatatt cctcaaagcg gaagcaaggg ttatgaggac aaggatgcaa agacatttgc
    15601 ttcatgggga attgattacc ttaaatatga taactgcaat atacctaacg gaagtgacat
    15661 gaaaaccgat taccagaaaa tgcagaccgc tcttgcaaat tgcggaagac caatagtatt
    15721 cagtatatgt gcatggggat atcagagctg gatgcctgca acaggtaatt tatggcgtac
    15781 taccggggat atcgctgata agtgggataa cggaaacgaa tggttcaaag gtattataaa
    15841 tgcaattgat ggtaatgcac aatacacaag ttcagccgca cccggtgcat ggaatgatcc
    15901 tgatatgctt gaaatcggaa acggtggatg tacaacagag gaataccgta cacagatgag
    15961 tatgtggagt atgatggctt ctccccttat tgcaggaaat gatataagga ccatgtcaca
    16021 gacaacaaag gatattctat tgaataagga agtaatagca atagaccagg atcctgcagg
    16081 agttcaggga aaaagagtta aaagtgcaaa tggtcttgag atttgggtaa aaccactggg
    16141 tacgaatggt acaactaagg cagttgcttt attgaacagg aattcggcaa catccaatat
    16201 tacagttaat tggtcagata taggtgtaag tggaagtgtt acggtcaggg atttgtgggc
    16261 taaatctgac aaaggcagtt ttacgggctc atacacagcg tctgttcctt cacatggaac
    16321 tgttttgatt aagatttcca ctgagccgcc ggcacctgtt gatgcaacaa agcaaataga
    16381 agcagagagt tatagcaatc agtcaggaat ccagacagaa acctgttcgg aaggcggaga
    16441 ggatgtaggc tttatcgaaa acggggacta tactgtttac agcaatgtgg atttcggtga
    16501 tggagtcgga ggcttccagg caagagtagc aagtgcgacc agcggaggca atattgagat
    16561 tagacttgac agccctgccg ggactttaat tggaacctgt ccggttgccg gaacagggga
    16621 ttggcagact tatactgatg taaaatgtac tgtcagcggg gcaacaggaa aacatgatgt
    16681 ataccttgta tttaaaggag atagcggata tttattcaac cttaattggt tcacatttac
    16741 tccaggaagt gtcaatacgg gtacattggg tgatttaaat tccgacggac aagtagacgc
    16801 gatagattta cagttattga aaaagtatat tttaggactg ggagcaatcg aaaatacaaa
    16861 actggcagat ttggatgcca acggagatat caatgcaata gatttttcac tgctgaaaca
    16921 attcttacta ggcataagga ccagctttcc ggggcagggg gcagcataat ttagcgatat
    16981 cctgatagga ggttgaaaat gaaaagaaag attttatctg ttcttttgct tgtcacaatg
    17041 actacagcat tgttttcagc tacaccgatg aataccgctt cagccgcaag tacggacttt
    17101 gtactagacg gaaacaatat caaagcgggc aacatcaacg gtctcacatt taaggggttc
    17161 ggcgtcctca gtggaaacag ctcaagtgca ctgttgatgg attacaagtc ggagcatcct
    17221 gagaaatata cagaattact gcaaattctg ttcggtggaa aaaatccgat tatgacacat
    17281 gtcaaaattg agatgggtaa tgaccgtaac aactccaccg gaccagatcc ctcaacaatg
    17341 cgttgggaaa atgagacggc taatgtcaaa agacaccccg gatttcaact tgcggctgat
    17401 gccaagaagg tgaaccccaa tcttaaagtc agcatattac gctggaatgc ccccggttgg
    17461 gcaaatagca atgataagat ttatacatgg tataagaaca ccatattagc agcataccgt
    17521 caatatggtt atatgattga ttacgtaaac ccgggggtca acgaacaaac accgaattta
    17581 acctggacta agcaatacgc ccagcgtatc aaaacagaca gtacaggttt taacaatgct
    17641 gaagaacggg cactttacaa caatattaag gtggtgattt ccgacgaagt ttccgtcggt
    17701 tccttcgggg atgatatggt cagtgattcc acccttcgtg atgccgtatc tgtcgctgca
    17761 tatcactata atactgatga caatagcttg ggaagtttca aacagcttgc cgaatccttt
    17821 gacaaagagg tgtggaatag tgaagcacag gccactttta gtaattcgtc ctttcgtccc
    17881 aataacaata tgaaagatcc aacagtagca ggaaccggca taggaggcac aaatgggcca
    17941 ctggaaatgg gaaatactgt tataaagggg tttgtaaatt caaggaggac acattttatc
    18001 tatcagccag tcattgggtc cttctatgag ggtgggcagt actcttttaa ggaattggta
    18061 tccgcacgtg atccttggtc cgggtggatt cactatgatg ccggtcttgt catacttcgg
    18121 catttcagtt ggttttcaaa ggctggctgg gaaaatgaga gtaataccgc aggggtttgg
    18181 agggctgtac ctcaggcgag tttcacaggt gcgacgggta cgaatcctgt taatgggcgt
    18241 aatggcactc ccagttatat gacactagct tctccggaca agcatgattt ttcaactatc
    18301 ttcattaacg atagtgaata ttccaaaacc tacacgttta agaccatcaa tatggcttat
    18361 tcgggaaacc cctcgctgga agtatgggaa actagagcag ctgataaggg agcatctttt
    18421 aatagtaatt acatgaagta cactggaacg gtttccacaa atagcagcgg agtttataca
    18481 gtaaacgtaa aaccttattc gattgttaca gttacaacat taagtaacag tggaaaagca
    18541 gagttcaata cgcctcttcc ggtggagggg gaccgcccgg ttctggatac agacaagaca
    18601 ggttcaatgc aggataccag ggataatata ttatatgctg acaactttga ttattccagc
    18661 aaaactgccc ctgtcatagc ggagggggga caaatcacag gaacccaaag ttatatagat
    18721 tcccgaggag gctcaaaaag tgctatacca cgttatgcca gcgacagaaa cggtgcattt
    18781 gaagtgtatc ttcctgacgg gtccagcaac tatatccttc gccaacaggt gaatcagtca
    18841 agtatggggc ttgggggcac atggaataat ggtaatccaa tcaccggcat tggagataac
    18901 cgttggatga actataaggc aagtgtggat gtttcatttg aacacaacag tacagagggc
    18961 ggtaacaatt atgctgcaat cggtgccaga cagcagggtg gtgaaaattc acactactta
    19021 aatggtactc cttatatact gaaattctgg tttgacggcg gttggtcgct actagtaaat
    19081 ggaagttccg tggcaaatgg taatgtagca agcggctcgg gtggagtgaa aatcagtggt
    19141 tttaatacag cttataatgc atggcataac atctctatca tggttgcaga caataaggtg
    19201 actgcgtatc tggacaatac catcctttat acctatacag atactaccca aagattgtcc
    19261 gggcgtattg atctggcaag cggctattac aatacttgtt ttgacaattt gaaggttgaa
    19321 acaatagacg gttatgcacc ttactactct gaaatgctgg acaatctgga aatgtacgat
    19381 ttgtcttctg tttctgctac aaagcttgtt tacggcggtt cttgggcaca tgaaaacggc
    19441 aaatccatgt acaattacca acgatcactt tccacgagcc agggaatagg tgctactatt
    19501 cagtattcat tcactggcac cgggctggac attcttggag ccaacaacgg ttctgctaag
    19561 ttagaggtaa ctgttgatgg aagagttgtt aattcctcag tgggaaccat ggtttcaggg
    19621 aatttacacc aaaactttac gcttcacggt cttgagtacg gtaagcatac ggtttgtttg
    19681 aaggtgttaa gtggtactat ggttgtcgat gctgttgggg ttgttgcaaa catagccggt
    19741 gcttcggaga tacccgttga acaatctgcg tattcaagga tagaagcaga gagctacagc
    19801 aaccagtcag gaatccagac agaaacctgt tcggaaggcg gagaggatgt gggctttgtt
    19861 gaaaacggcg actatactgt ttacaacaat gtggatttcg gcgatggtgt cggaggcttc
    19921 caagcaagag tagcaagtgc aaccagtgga ggcaatattg agatcaggct tgacagctct
    19981 accgggactt tgataggaac ttgtcctgtt gccggaacag gggattggca gacttatact
    20041 gatgcaaaat gtactgtcag cggggtaaca ggaaaacatg atgtatacct tgtatttaaa
    20101 ggagatagcg gatatttatt taatcttaac tggtttacat ttagtgagaa aactgtcata
    20161 gggaatttgg gtgatataaa ctcggacgga caagtagatg caatagattt acaggtattg
    20221 aaaaagtatc ttttgcaact aggggaaatt ggagatacga agctggcaga tttggatgcc
    20281 aacggagaaa ttaacgcaat cgatttttca ttactcaaac aatttttact gggtactatt
    20341 attagttttc cgggagaagc actataaggg gacatcaccg ttccatatgt gtgaagaatt
    20401 acaaatataa tataaggagg cttttttggt atgttgagaa agaaaatttt atgtatattt
    20461 cttgtgactg tattaatgct aactatatta ccaatacctc aacagacggt aatggctgat
    20521 acaggggtac ttaaggaact taaaggaact gacatctaca acggattaag gggactgaat
    20581 tttaacgagg gttggaaatt caataagggg gatgtaagca acggccagag taccgggtat
    20641 aatgacagcg gctggtcagg tgttacactg ccacatgact ggagtattta taacactttt
    20701 aataaatcct cagcagcggg tgcaggagga ggttatctgg atggaggaat cggatggtac
    20761 aggaaaacct ttaccgtacc ttcggattat acaggaaaga aggtattcat tgaattcgac
    20821 ggagcgtaca tgaacagcca ggtatggatt aacggtactt tgctgggaac ccgtccatat
    20881 ggctattcat cctttgaata tgatttaact ccatacctca atataggtgg aagtaatgtt
    20941 attgcagtaa ggctcaacaa taaccaaccc actagccgct ggtattcagg aagcggtatt
    21001 tatcggaatg tatggctgac agtattagat cctgtgcatg tgacatactg cggaatgttt
    21061 gtaacaacac ccacggtcag cagcagttcg gccaccgcaa acgtcagcac aaaggtattg
    21121 aatcagggaa gtactgcaaa atcggtatca ttaaaaacta caattaccga tgcggagggt
    21181 aatgtcgtag ccacaaatac ttcttcagtg gctagtatag ctggcagtgg tagcaatacc
    21241 ttcagtcaga atctgacagt atcaaacccg catttatggt ctcccgcttc accataccta
    21301 tatgctgttc aaacccaggt tattgtggac ggaaatgtaa cagatacata tagttctaca
    21361 ttgggaatca gatatttcag ctttagctcc acatcaggct tttcacttaa tggtgtaaat
    21421 atgaagataa atggagtgtg tctgcatcat gatttgggtt ctcttggtgc ggctgttaac
    21481 tatcgtgcaa ttgaaagaga acttcagatt atgaaggata tgggatgtaa tgcaattcgt
    21541 acttcacata acccgccaga cccgcaaatg ctggaaatat gtgacagatt aggtttgatg
    21601 gttatggatg aagcatttga ctgctgggaa acaggaaaaa attctaatga ctaccatctg
    21661 tactttaaca attgggcaca gaccgatctt caagcaatgg ttacaaggga tcgtaatcat
    21721 ccgtcaatta tcatgtacag cataggcaat gagattcctt caccaagtgt agctacagcg
    21781 acaaagctta agaattgggt aaaagatgtt gataacacac gaccagtcac attgggaact
    21841 ttcgccgtaa gcatgggtga tgcaactccg caggcggtcg caagtgttct tgatttagtg
    21901 ggctataact attttccata catgtacgac ggaggacata acaatcatcc ggagtggaag
    21961 atgtttggaa gtgaaacgag ttcagcggtc agaagccgcg gggtttataa aacacccacc
    22021 aataaaaaca tcctgactga cagtgataac cagtgttcct cttatgataa cagtgtggtc
    22081 agctggggca acagtgctga atcttcctat aatgaaatta ataaaagaaa ttacatggcg
    22141 ggtgaattca tatggacagg atttgactat atcggtgaac ctacacctta cgaatggccg
    22201 gcaaaaagtt cgtattttgg aatagtggat acatgcgggt tcccgaaaga tatctactat
    22261 ttctatcaaa gtaagtggag tactaaaccg atggttcaca tactcccaca ttggaactgg
    22321 tctacgggta ctaatgtaga ggtatgggca tacagtaact gcgatactgt agaactattc
    22381 cttaatggga agtcacttgg ctcgaaaagc gttggaacag caggacatct ttcatggagt
    22441 gttccatggt cttcagggac attgcgggca aaaggtacaa agggcggcac tgtggtatac
    22501 gatgaagtcg tcacagcagg tactccttca aaagtcctgt tgaagcctga cagaacttct
    22561 gttaaagcag acggtaagga tttgatatat atcgaaacag atattgcaga cggcaacaat
    22621 gtgactgtcc ccacagctga caatacagtg aatttctcca tatcaggtcc cggtgtaatt
    22681 gtgggagttg ataatggaaa tccaataagt acggaagcat ataaaggcag cagtcgtaag
    22741 gctttcaacg gtaagtgtct ggtaattgtc cagcctacca aagttaatgg aacaattgta
    22801 gtaacggcaa gctccaacgg actatcctct ggaagtgttt ccatcgcttc aacaggagga
    22861 gcagaagcac ccatcgtatc tgcctataaa aagattgagg ccgaaaacta cgataatcag
    22921 tctggaatcc agacagaagc ctgttcggaa ggcggacagg atgtaggatt tattgaaaac
    22981 ggggactaca ctgtttacaa caatgtggat ttcggtagcg gtgccgagag ctttacggca
    23041 agagcagcaa gtgctactag cggaggaaat attgagatca gacttgacag tcctaacggg
    23101 actttaattg gaacttgtcc agttgcagga acaggtgatt ggcagactta tgctgatgta
    23161 aattgcagtg tcagcgaggt aagcggaaaa cacgacctgt atctaaaatt caccggggat
    23221 agcggatatt tatttaatat taactggttt acatttactg cacggaattc agcaaaattg
    23281 ggagatttga attccgatga ccaaatagac gcgatggatt tccagttgat gaaaaagtat
    23341 ctgctgggac tgggagaaat taaagataca aagctggccg atttggatgc aagtggtact
    23401 attgatgttt tagatctgat gctgctcaaa cagtacctgc taggcactat aacttctttt
    23461 ccggggcagg gtacttaa
//
