LOCUS       CR626927               13650 bp    DNA     linear   BCT 06-FEB-2015
DEFINITION  Bacteroides fragilis NCTC 9343, complete genome.
ACCESSION   CR626927
VERSION     CR626927.1
DBLINK      BioProject: PRJNA46
            BioSample: SAMEA1705957
KEYWORDS    complete genome.
SOURCE      Bacteroides fragilis NCTC 9343
  ORGANISM  Bacteroides fragilis NCTC 9343
            Bacteria; Bacteroidetes; Bacteroidia; Bacteroidales; Bacteroidaceae;
            Bacteroides.
REFERENCE   1  (bases 1 to 13650)
  AUTHORS   Cerdeno-Tarraga,A.M., Patrick,S., Crossman,L.C., Blakely,G.,
            Abratt,V., Lennard,N., Poxton,I., Duerden,B., Harris,B., Quail,M.A.,
            Barron,A., Clark,L., Corton,C., Doggett,J., Holden,M.T., Larke,N.,
            Line,A., Lord,A., Norbertczak,H., Ormond,D., Price,C.,
            Rabbinowitsch,E., Woodward,J., Barrell,B. and Parkhill,J.
  TITLE     Extensive DNA inversions in the B. fragilis genome control variable
            gene expression
  JOURNAL   Science 307 (5714), 1463-1465 (2005)
   PUBMED   15746427
REFERENCE   2  (bases 1 to 13650)
  AUTHORS   Cerdeno-Tarraga,A.M.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-JUL-2004) Cerdeno-Tarraga A.M., submitted on behalf of
            the Pathogen Sequencing Unit, Sanger Institute, Wellcome Trust
            Genome Campus, Hinxton, Cambridge CB10 1SA E-mail: amct@sanger.ac.uk
COMMENT     Accession number for plasmid pBF9343 in this genome project:
            CR626928.
FEATURES             Location/Qualifiers
     source          1..13650
                     /organism="Bacteroides fragilis NCTC 9343"
                     /mol_type="genomic DNA"
                     /culture_collection="ATCC:25285"
                     /culture_collection="NCTC:9343"
                     /type_material="type strain of Bacteroides fragilis"
                     /db_xref="taxon:272559"
     gene            complement(<1..915)
                     /locus_tag="BF9343_3582"
     CDS             complement(<1..915)
                     /locus_tag="BF9343_3582"
                     /old_locus_tag="BF3682"
                     /note="Similar to Legionella pneumophila lipopolysaccharide
                     biosynthesis WecA protein SWALL:Q9RDY5 (EMBL:AJ007311) (334
                     aa) fasta scores: E(): 1.9e-12, 29.97% id in 337 aa, and to
                     previously sequenced Bacteroides fragilis putative
                     UndPP-QuiNAc-p-transferase WcgX SWALL:Q9F748
                     (EMBL:AF285774) (316 aa) fasta scores: E(): 6.7e-107,
                     80.95% id in 315 aa, and to previously sequenced
                     Bacteroides fragilis putative
                     UDP-GlcNAc:undecaprenylphosphate GlcNAc-1-phosphate
                     transferase WcfL SWALL:Q9XDJ1 (EMBL:AF048749) (318 aa)
                     fasta scores: E(): 1.1e-106, 79.55% id in 313 aa"
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|P0AC78|9.B.146.1.7"
                     /protein_id="CAH09363.1"
                     /db_xref="EnsemblGenomes-Gn:BF9343_3582"
                     /db_xref="EnsemblGenomes-Tr:CAH09363"
                     /db_xref="GOA:Q5L969"
                     /db_xref="InterPro:IPR000715"
                     /db_xref="InterPro:IPR016196"
                     /db_xref="UniProtKB/TrEMBL:Q5L969"
                     /translation="MYYILILVLLFLAELFYFRIADKCNIIDKPNERSSHTRITLRGGG
                     IIFYLGALTFFLTNQFEYPWFILALTLITFISFVDDIRSTSQGLRLVFHFMAMALMFYQ
                     WGLFSLPWWTLLVALIVCTGIINAYNFMDGINGITGGYSLVILISLAYVNAEVIFFTEQ
                     SFIYTMICSVLVFDFFNFRKRAKCFAGDVGSVSIAFVVLFLIGSLIFQTKDFSWLVLLV
                     VYGVDSVLTIVHRLLLHENIGLPHRKHLYQIMANELKIPHVAVALTYMSVQTVVLVGYL
                     LLREYGYGYLLGSILVLGLLYFLFMKRFFYLHKSN"
     misc_feature    <1..>13650
                     /note="PS_5/PS_D lipopolysaccharide biosynthesis locus;
                     label: PS_D"
     misc_feature    complement(order(1..60,70..138,199..267,286..354,373..426,
                     436..504,523..582,592..645,679..732,742..795,853..906))
                     /locus_tag="BF9343_3582"
                     /note="11 probable transmembrane helices predicted for
                     BF3682 by TMHMM2.0 at aa 4-21, 41-58, 62-79, 91-108,
                     112-131, 138-160, 164-181, 188-210, 217-239, 260-282 and
                     286-305"
     misc_feature    complement(286..729)
                     /locus_tag="BF9343_3582"
                     /note="Pfam match to entry PF00953 Glycos_transf_4,
                     Glycosyl transferase, score 10.2, E-value 1.7e-08"
     gene            complement(1031..1927)
                     /locus_tag="BF9343_3583"
     CDS             complement(1031..1927)
                     /locus_tag="BF9343_3583"
                     /old_locus_tag="BF3683"
                     /note="Similar to Edwardsiella ictaluri UDP-glucose
                     4-epimerase WbeIT SWALL:Q937X6 (EMBL:AY057452) (323 aa)
                     fasta scores: E(): 2.2e-14, 28.3% id in 318 aa, and to
                     Bacteroides thetaiotaomicron putative BT2887 SWALL:AAO77993
                     (EMBL:AE016937) (326 aa) fasta scores: E(): 1.5e-13, 27.21%
                     id in 316 aa, and to Fusobacterium nucleatum
                     UDP-N-acetyl-D-quinovosamine 4-epimerase FN1694
                     SWALL:Q8R6F9 (EMBL:AE010474) (290 aa) fasta scores: E():
                     1.3e-12, 28.28% id in 304 aa"
                     /codon_start=1
                     /transl_table=11
                     /product="DNTP-hexose dehydratase-epimerase"
                     /protein_id="CAH09364.1"
                     /db_xref="EnsemblGenomes-Gn:BF9343_3583"
                     /db_xref="EnsemblGenomes-Tr:CAH09364"
                     /db_xref="GOA:Q5L968"
                     /db_xref="InterPro:IPR001509"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:Q5L968"
                     /translation="MNLLFTGASGFLGRNICFLLKEKYKIDTMGLALQDNYKVDIAQEI
                     PTLNMPYDVVLHAAGKAHSIPKTEVEKQTFFDINLQGTKNLCTALENFCTPKAFIFIST
                     VAVYGCDFGENITEEYSLNGTSPYALSKIKAEKYLEGWCSMHNVKLSILRPSLIAGPNP
                     PGNLGTMIHGIKSGKYLSIAGGKARKSVLMVQDIANLVPLLVEKGGIYNVCDTYQPSFR
                     ELEEIICNQLNKKLPLSIPYYFAKGMAVVGDCLGEKAPINSLKLRKITNSLTFSNEKAV
                     RELGWKPVNVLESFRIE"
     misc_feature    complement(1598..1630)
                     /locus_tag="BF9343_3583"
                     /note="PS00013 Prokaryotic membrane lipoprotein lipid
                     attachment site."
     gene            complement(1924..2676)
                     /locus_tag="BF9343_3584"
     CDS             complement(1924..2676)
                     /locus_tag="BF9343_3584"
                     /old_locus_tag="BF3684"
                     /note="Similar to Escherichia coli, and Escherichia coli
                     O157:H7 glycosyl transferase WbhA or WbdN or Z3204 or
                     ECS2845 SWALL:Q9S5F4 (EMBL:AB008676) (260 aa) fasta scores:
                     E(): 1.1e-28, 40.24% id in 241 aa, and to Bacillus
                     halodurans teichuronic acid biosynthesis Tuag or BH3661
                     SWALL:Q9K6R6 (EMBL:AP001519) (257 aa) fasta scores: E():
                     6.7e-37, 42.51% id in 247 aa, and to Oceanobacillus
                     iheyensis glycosyltransferase ob2925 SWALL:Q8EMC7
                     (EMBL:AP004603) (258 aa) fasta scores: E(): 7.8e-37, 40.72%
                     id in 248 aa"
                     /codon_start=1
                     /transl_table=11
                     /product="GT2|GT2_Glycos_transf_2"
                     /protein_id="CAH09365.1"
                     /db_xref="EnsemblGenomes-Gn:BF9343_3584"
                     /db_xref="EnsemblGenomes-Tr:CAH09365"
                     /db_xref="GOA:Q5L967"
                     /db_xref="InterPro:IPR001173"
                     /db_xref="InterPro:IPR029044"
                     /db_xref="UniProtKB/TrEMBL:Q5L967"
                     /translation="MNELVSIITPCYNSAATIRETIRSVIAQSYVNWELLIIDDCSNDD
                     SVKIIMEFMDTDSRIYYLKTEHPSGGPTLPRNVGIQAAKGRFIAFLDSDDIWLPNKLST
                     QLPLFINDNVAIVYSDYEKISEEGNRTGRIVKSDPYHHYKSLLCGNELGCLTVVYDTQK
                     IGKRYFKFIGHEDYNLWLDILKEGFIAINTNICLALYRIRKGSVSSNKLRVIKWIWHIY
                     RVEQKKTIWLSLYYSLSDLNKSLFKYLK"
     misc_feature    complement(2170..2661)
                     /locus_tag="BF9343_3584"
                     /note="Pfam match to entry PF00535 Glycos_transf_2,
                     Glycosyl transferase, score 147.3, E-value 2.2e-41"
     gene            complement(2721..3554)
                     /locus_tag="BF9343_3585"
     CDS             complement(2721..3554)
                     /locus_tag="BF9343_3585"
                     /old_locus_tag="BF3685"
                     /note="Similar to Streptococcus agalactiae
                     galactosyltransferase CpsIBI SWALL:Q9AQJ0 (EMBL:AB050723)
                     (324 aa) fasta scores: E(): 3.4e-12, 31.15% id in 199 aa,
                     and to Streptococcus agalactiae CpsI or CpsIAI SWALL:Q8VL99
                     (EMBL:AF363060) (266 aa) fasta scores: E(): 4e-12, 28.62%
                     id in 262 aa, and to Streptococcus agalactiae CpsIAI or
                     CpsI SWALL:Q8VLB0 (EMBL:AF332893) (324 aa) fasta scores:
                     E(): 4.7e-12, 28.62% id in 262 aa"
                     /codon_start=1
                     /transl_table=11
                     /product="GT2|GT2_Glycos_transf_2"
                     /protein_id="CAH09366.1"
                     /db_xref="EnsemblGenomes-Gn:BF9343_3585"
                     /db_xref="EnsemblGenomes-Tr:CAH09366"
                     /db_xref="GOA:Q5L966"
                     /db_xref="InterPro:IPR001173"
                     /db_xref="InterPro:IPR029044"
                     /db_xref="UniProtKB/TrEMBL:Q5L966"
                     /translation="MTMLLSIIVPTFKPQKTYFEECLFSLFNQTMFHYLYEVIVVLNGD
                     IDTQYTDMILDIFAYKPAGLYCRLIKTDQAGVSNARNLGIDAAKGQYIGFVDDDDIVSS
                     DYLEELCKISSRNIVGVSNVHTFRKTIEEKEDNFFACRIIQQRECQYSLFRNRAILAFP
                     VAKLIHRDIIGNRRFNPRFKNGEDALFMTEISDLIGGFRFTKEYTTYYVRERAGSASRR
                     PLKRGQLCWDTFMLIKAYVSIYLSSPFSYNFLLFASRIPGSIKGAIKLSRNTAFF"
     misc_feature    complement(3033..3539)
                     /locus_tag="BF9343_3585"
                     /note="Pfam match to entry PF00535 Glycos_transf_2,
                     Glycosyl transferase, score 73.7, E-value 3.2e-19"
     gene            complement(3583..4668)
                     /locus_tag="BF9343_3586"
     CDS             complement(3583..4668)
                     /locus_tag="BF9343_3586"
                     /old_locus_tag="BF3686"
                     /note="Similar to Streptococcus thermophilus
                     exopolysaccharide biosynthesis EpsJ or Wzy SWALL:Q56047
                     (EMBL:U40830) (360 aa) fasta scores: E(): 8.3e-11, 22.96%
                     id in 344 aa, and to Bacteroides thetaiotaomicron conserved
                     hypothetical protein BT1710 SWALL:AAO76817 (EMBL:AE016932)
                     (370 aa) fasta scores: E(): 1.7e-16, 24.46% id in 372 aa,
                     and to Bacillus subtilis hypothetical protein YveQ
                     SWALL:P71056 (EMBL:Z71928) (367 aa) fasta scores: E():
                     5.9e-13, 23.86% id in 373 aa"
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|P71056|9.B.183.1.9"
                     /protein_id="CAH09367.1"
                     /db_xref="EnsemblGenomes-Gn:BF9343_3586"
                     /db_xref="EnsemblGenomes-Tr:CAH09367"
                     /db_xref="UniProtKB/TrEMBL:Q5L965"
                     /translation="MIPYAFIILLVVFFSVFDFSNLNVFKKKILLFFLSFILILFVGTR
                     FETGDDWGEYTKVFDKIPLVSDLWNDNGMFLLFRMEPGYILFNSVIKSFGGSINEVFLL
                     SSIVVISLFFVFQKRYTLLPFLAVLLYMRYGYMQFNMMFVRQGIAISIFFYSLKYIEDK
                     KIIKYLLINILSSLFHSSLLIVLPLYFVINRRYSNIFLCTVVFISVLLSFFDWMGAILS
                     FFPPFIQSSLTSYTESDVWGGMTGKINIAVAEKFILLLMCLRLREKLEQKNISFNLVFN
                     LFVLSIICYYAFFQTYVFQQRTVLIFQLSTIFIISQLFLFFSVKNRMMVLFILNLMVIY
                     FFFRYINIGKDVYLPYRSWLI"
     misc_feature    complement(order(3625..3684,3703..3762,3775..3843,
                     3880..3948,4006..4074,4093..4161,4204..4263,4321..4389,
                     4531..4584,4603..4659))
                     /locus_tag="BF9343_3586"
                     /note="10 probable transmembrane helices predicted for
                     BF3686 by TMHMM2.0 at aa 4-22, 29-46, 94-116, 136-155,
                     170-192, 199-221, 241-263, 276-298, 303-322 and 329-348"
     gene            complement(4665..5651)
                     /locus_tag="BF9343_3587"
     CDS             complement(4665..5651)
                     /locus_tag="BF9343_3587"
                     /old_locus_tag="BF3687"
                     /note="Similar to Vibrio cholerae sugar transferase
                     SWALL:O34234 (EMBL:Y07786) (337 aa) fasta scores: E():
                     1.9e-43, 42.98% id in 342 aa, and to Vibrio cholerae
                     ORF139-19 protein SWALL:P74947 (EMBL:AB012956) (337 aa)
                     fasta scores: E(): 1.4e-43, 43.36% id in 339 aa, and to
                     Vibrio cholerae WblC protein wblC SWALL:O87159
                     (EMBL:AB012957) (340 aa) fasta scores: E(): 1.9e-32, 36.09%
                     id in 338 aa"
                     /codon_start=1
                     /transl_table=11
                     /product="GT2|GT2_Glycos_transf_2"
                     /protein_id="CAH09368.1"
                     /db_xref="EnsemblGenomes-Gn:BF9343_3587"
                     /db_xref="EnsemblGenomes-Tr:CAH09368"
                     /db_xref="GOA:Q5L964"
                     /db_xref="InterPro:IPR001173"
                     /db_xref="InterPro:IPR029044"
                     /db_xref="UniProtKB/TrEMBL:Q5L964"
                     /translation="MNSNPFVSVVMSVYNGGEFLKDAINSILSQSYKNFEFIIINDGSS
                     DNFSEILELYDDERIKVLNNQENKGLVYSLNRGLLESIGKYIVRMDADDISLPNRIEKQ
                     VEFMEREPEVGVCGSYIEIFGDTIKRKVQRFPSNVNVNEAFLLFSTCLAHPSVIIRKSI
                     VDKYKLRYDDRYLHAEDYAIWCQAVKYTKISNIREVLLKYRILESSVTRQANKNFQSRF
                     DVHKSIYKDIFRNKGIDYTEKELYLHFIISDNNRFRNQALTIRPSEINAHLTKILSHYR
                     GASNYKYIAFLVNKRGLSLSRWYSESRGFYFIMYLFKFLYYKIQIKK"
     misc_feature    complement(5148..5630)
                     /locus_tag="BF9343_3587"
                     /note="Pfam match to entry PF00535 Glycos_transf_2,
                     Glycosyl transferase, score 149.6, E-value 4.8e-42"
     gene            complement(5648..6517)
                     /locus_tag="BF9343_3588"
     CDS             complement(5648..6517)
                     /locus_tag="BF9343_3588"
                     /old_locus_tag="BF3688"
                     /note="Similar to Vibrio cholerae O-antigen-related WblA
                     protein SWALL:O87157 (EMBL:AB012957) (281 aa) fasta scores:
                     E(): 9.1e-35, 36.39% id in 283 aa, and to Synechococcus
                     elongatus TLR2316 protein SWALL:Q8DGK1 (EMBL:AP005377) (293
                     aa) fasta scores: E(): 1.1e-33, 41.58% id in 291 aa, and to
                     Synechococcus elongatus alpha-1,2-fucosyltransferase
                     tll0994 SWALL:Q8DK72 (EMBL:AP005372) (293 aa) fasta scores:
                     E(): 5.4e-32, 41.15% id in 294 aa"
                     /codon_start=1
                     /transl_table=11
                     /product="GT11"
                     /protein_id="CAH09369.1"
                     /db_xref="EnsemblGenomes-Gn:BF9343_3588"
                     /db_xref="EnsemblGenomes-Tr:CAH09369"
                     /db_xref="GOA:Q5L963"
                     /db_xref="InterPro:IPR002516"
                     /db_xref="UniProtKB/TrEMBL:Q5L963"
                     /translation="MFFRCCMKIVQIIGGLGNQMFQFAFYLALKEKYVNVKLDTSSFGA
                     YTHNGFELDKVFHVEYLKASIRERIKLSYQGSEIWIRVLRKLLKRKKTEYVEPYLCFDE
                     NAISLSCDKYYIGYWQSYKYFTNIEAAIRGQFHFSKVLSDKNEFIKKQMQNSNSVSLHV
                     RLGDYVNNPAYSNICTSAYYNKAINIIQSKVSEPKFFVFSDDTVWCKDHLKIPNCHIID
                     WNNKEESYWDMCLMTYCKHNIIANSSFSWWGAWLNTNPERIVIAPGKWINDDRVQVSDI
                     IPSDWICV"
     misc_feature    complement(5651..6499)
                     /locus_tag="BF9343_3588"
                     /note="Pfam match to entry PF01531 Glyco_transf_11,
                     Glycosyl transferase family 11, score 22.7, E-value
                     6.9e-10"
     gene            complement(6551..7531)
                     /locus_tag="BF9343_3589"
     CDS             complement(6551..7531)
                     /locus_tag="BF9343_3589"
                     /old_locus_tag="BF3689"
                     /note="Similar to Vibrio cholerae O-antigen-related WbfL
                     protein SWALL:O87156 (EMBL:AB012957) (346 aa) fasta scores:
                     E(): 2.3e-05, 36.36% id in 110 aa, and to Helicobacter
                     pylori alpha1,3-fucosyltransferase FucT SWALL:O30511
                     (EMBL:AF008596) (478 aa) fasta scores: E(): 0.00021, 38.14%
                     id in 97 aa, and to Helicobacter pylori J99 alpha- JHP1002
                     SWALL:Q9ZKD7 (EMBL:AE001528) (436 aa) fasta scores: E():
                     0.00026, 32% id in 125 aa"
                     /codon_start=1
                     /transl_table=11
                     /product="GT0|GT10"
                     /protein_id="CAH09370.1"
                     /db_xref="EnsemblGenomes-Gn:BF9343_3589"
                     /db_xref="EnsemblGenomes-Tr:CAH09370"
                     /db_xref="GOA:Q5L962"
                     /db_xref="InterPro:IPR001503"
                     /db_xref="UniProtKB/TrEMBL:Q5L962"
                     /translation="MKKVFIPINTKIPVERQFPNRVPIWGNYEFIISTKEPEQEYDYVV
                     VLDDIEYSLRLMCCKQNICLFTGEPPYVKLYPRKYLNQFGHVYTCQSSVLKRDNACLSY
                     PALPWMLYYNFYNDKQKEELLIDYDFLKNRPTLQRKNKICLFTSNKKISKGHIERIKFA
                     LKLQEEMPDLIDIYGSGFTNVDYKYEVMVQYKYAIVIENCSYPYYWTEKLADTFLSGCY
                     PIYFGDPHIGDFFSKEEMAVIDIRNFDESKQTIKKIIDNNVYEKQYENICHARDKILDK
                     YNMFSLISSTLDSIPAKLDKEKLLLSPMRLSVFDRIRNRIYRLFY"
     gene            complement(7567..8199)
                     /locus_tag="BF9343_3590"
     CDS             complement(7567..8199)
                     /locus_tag="BF9343_3590"
                     /old_locus_tag="BF3690"
                     /note="Similar to Staphylococcus aureus putative O-acetyl
                     transferase (capsular polysaccharide synthesis enzyme
                     o-acetyl transferase) Cap5H or CapH or sav0156 or sa0151
                     SWALL:P72386 (EMBL:U77308) (208 aa) fasta scores: E():
                     3.5e-16, 40.71% id in 167 aa, and to Leptospira interrogans
                     probable macrolide acetyltransferase la3679 SWALL:Q8F018
                     (EMBL:AE011523) (218 aa) fasta scores: E(): 3.1e-16, 40.26%
                     id in 149 aa, and to Agrobacterium tumefaciens acetyl
                     transferase atu1146 or agr_c_2119 SWALL:Q8UG93
                     (EMBL:AE009077) (210 aa) fasta scores: E(): 3.5e-16, 38.75%
                     id in 160 aa"
                     /codon_start=1
                     /transl_table=11
                     /product="putative O-acetyl transferase (capsular
                     polysaccharide synthesis enzyme o-acetyl transferase)"
                     /protein_id="CAH09371.1"
                     /db_xref="EnsemblGenomes-Gn:BF9343_3590"
                     /db_xref="EnsemblGenomes-Tr:CAH09371"
                     /db_xref="GOA:Q5L961"
                     /db_xref="InterPro:IPR001451"
                     /db_xref="InterPro:IPR011004"
                     /db_xref="InterPro:IPR018357"
                     /db_xref="UniProtKB/TrEMBL:Q5L961"
                     /translation="MLVLYRASIRFKLRKNKNSFDSSNYFYGGNNICIINTKWGKHSGI
                     GGYAEIIDTLVGNFTNISSWAKIGIRDHIHTNFLICDFVYKDNDHIMPPGISSFEDYWV
                     KIGNDVWVGTNVTILRGVEVGDGAVIAAGSVVTKSIPPYAIVGGNPAKFIKWRFPFEVR
                     EKLLEIKWWDWDDDLIKEKKDYLQNLVGFDMDKYKIEYRKRKEDLFY"
     misc_feature    complement(7780..7866)
                     /locus_tag="BF9343_3590"
                     /note="PS00101 Hexapeptide-repeat containing-transferases
                     signature."
     misc_feature    complement(7786..7839)
                     /locus_tag="BF9343_3590"
                     /note="Pfam match to entry PF00132 hexapep, Bacterial
                     transferase hexapeptide (three repeats), score 13.6,
                     E-value 0.41"
     misc_feature    complement(7840..7893)
                     /locus_tag="BF9343_3590"
                     /note="Pfam match to entry PF00132 hexapep, Bacterial
                     transferase hexapeptide (three repeats), score 9.6, E-value
                     4"
     misc_feature    complement(8041..8094)
                     /locus_tag="BF9343_3590"
                     /note="Pfam match to entry PF00132 hexapep, Bacterial
                     transferase hexapeptide (three repeats), score 0.9, E-value
                     51"
     gene            complement(8219..9070)
                     /locus_tag="BF9343_3591"
     CDS             complement(8219..9070)
                     /locus_tag="BF9343_3591"
                     /old_locus_tag="BF3691"
                     /note="no significant database matches"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="CAH09372.1"
                     /db_xref="EnsemblGenomes-Gn:BF9343_3591"
                     /db_xref="EnsemblGenomes-Tr:CAH09372"
                     /db_xref="InterPro:IPR029044"
                     /db_xref="UniProtKB/TrEMBL:Q5L960"
                     /translation="MKILGSFLKNIIQHTVFIRYFLDYIERRCNINSRMENDLYHEGWS
                     FIIITDGKSKEMLNFTIKSILDEFGEDRYEIIVIGQNRDYPQLNNKIKYISYYSLPFLA
                     GWITIKKNIGAKAAIYNKLVIMHDYVSLNRGWKVGFEEFGRDFDICMNRITLKNGNRTR
                     DWLVYDYPNIGPALLPYKIQCKKYQYISGTYFVVKKDFFINNLLDEKLRWGEGEDVEWS
                     KRVREKANIVFNNNSCVSFLKDKSPNDAPYCDNWIENTIKLYGMYSIDINKENYVEDIA
                     KY"
     gene            complement(9067..10599)
                     /locus_tag="BF9343_3592"
     CDS             complement(9067..10599)
                     /locus_tag="BF9343_3592"
                     /old_locus_tag="BF3692"
                     /note="Similar to Streptococcus thermophilus Eps operon
                     protein Eps11R SWALL:Q8GP39 (EMBL:AF454501) (500 aa) fasta
                     scores: E(): 3.6e-15, 21.83% id in 513 aa, and to
                     Clostridium perfringens probable flippase CPE0489
                     SWALL:Q8XN49 (EMBL:AP003187) (512 aa) fasta scores: E():
                     1.5e-46, 29.84% id in 516 aa, and to Clostridium
                     perfringens probable flippase CPE0505 SWALL:Q8XN33
                     (EMBL:AP003187) (506 aa) fasta scores: E(): 5.1e-44, 34.11%
                     id in 513 aa"
                     /codon_start=1
                     /transl_table=11
                     /product="possible flippase"
                     /protein_id="CAH09373.1"
                     /db_xref="EnsemblGenomes-Gn:BF9343_3592"
                     /db_xref="EnsemblGenomes-Tr:CAH09373"
                     /db_xref="UniProtKB/TrEMBL:Q5L959"
                     /translation="MRTNKALKNIFYSVFSYGSLFILSLILRKVFLKYIDIEYLGLDSV
                     FENMFSLMALVDVGTGSLISYLLYKAFSENNRREVSVLMSMYKKMYLFIAVAMGIISIF
                     LIPLLPILIKSKGFDWNYIIVIYLIRGIAMVGSYCFSYRRLLFKVDQCEYVCTKIDTIT
                     NYFKYLSWFIVIIATQSYIAYLIIQTISVFVANIIIARMSYTKYPYSKEVKVSIPDFRE
                     RNFFMDMKNVYMSKIAGTIFGSTNSLVLSSSLGVKSVAMLANYTLISEAIAAAFSKIFS
                     PLQGSIGNYVYSEDKAEGFKLFRMFELLSFIIGSTVSICFANLINPFISIWIGEKYVLS
                     LFIVILISMKLYIGFASHFVSCYREVFGRFEIDRFYNLGGALLSLFVSIMLVNSYGIAG
                     VYIGTIIGMLGFWIGRYKVLKEEYFGNISTGYIKRQLLRIVVLLVGYFITFVICSFLGN
                     GIIFFIAKLFVCISVISVMNYIIYRKTEEFQRMLFYFNRSKNVIINNLNNHR"
     misc_feature    complement(order(9154..9222,9232..9285,9343..9411,
                     9424..9477,9511..9579,9607..9675,9832..9891,10003..10098,
                     10174..10233,10261..10329,10396..10464,10507..10575))
                     /locus_tag="BF9343_3592"
                     /note="12 probable transmembrane helices predicted for
                     BF3692 by TMHMM2.0 at aa 9-31, 46-68, 91-113, 123-142,
                     168-199, 237-256, 309-331, 341-363, 375-392, 397-419,
                     439-456 and 460-482"
     gene            complement(10619..10942)
                     /locus_tag="BF9343_3593"
     CDS             complement(10619..10942)
                     /locus_tag="BF9343_3593"
                     /old_locus_tag="BF3693"
                     /note="Similar to Pseudomonas syringae conserved domain
                     protein Pspto0710 SWALL:AAO54252 (EMBL:AE016858) (98 aa)
                     fasta scores: E(): 2.2e-17, 54.63% id in 97 aa"
                     /codon_start=1
                     /transl_table=11
                     /product="conserved hypothetical protein"
                     /protein_id="CAH09374.1"
                     /db_xref="EnsemblGenomes-Gn:BF9343_3593"
                     /db_xref="EnsemblGenomes-Tr:CAH09374"
                     /db_xref="InterPro:IPR011051"
                     /db_xref="InterPro:IPR014710"
                     /db_xref="UniProtKB/TrEMBL:Q5L958"
                     /translation="MKTAKLEDMIKGWFIGNFEPTLLRTNDVEVAVKSYNKGDYEEKHY
                     HKIATEITVIVSGKVKMNGIEYSKGDIVVMEPNEATDFECLENGTQNVVVKLPGANDDK
                     YCL"
     gene            complement(10939..11670)
                     /locus_tag="BF9343_3594"
     CDS             complement(10939..11670)
                     /locus_tag="BF9343_3594"
                     /old_locus_tag="BF3694"
                     /note="Similar to Pasteurella multocida BcbE SWALL:Q9L9L0
                     (EMBL:AF169324) (236 aa) fasta scores: E(): 5.2e-11, 29.48%
                     id in 234 aa, and to Pseudomonas syringae
                     lipopolysaccharide biosynthesis protein, putative PSPTO0706
                     SWALL:AAO54248 (EMBL:AE016858) (253 aa) fasta scores: E():
                     4.9e-31, 43.26% id in 245 aa, and to Pseudomonas syringae
                     hypothetical protein PSPTO0709 SWALL:AAO54251
                     (EMBL:AE016858) (240 aa) fasta scores: E(): 1.8e-15, 30.08%
                     id in 236 aa"
                     /codon_start=1
                     /transl_table=11
                     /product="putative nucleotidyltransferase"
                     /protein_id="CAH09375.1"
                     /db_xref="EnsemblGenomes-Gn:BF9343_3594"
                     /db_xref="EnsemblGenomes-Tr:CAH09375"
                     /db_xref="GOA:Q5L957"
                     /db_xref="InterPro:IPR005835"
                     /db_xref="InterPro:IPR016873"
                     /db_xref="InterPro:IPR029044"
                     /db_xref="UniProtKB/TrEMBL:Q5L957"
                     /translation="MINIVIPMAGAGSRFAQAGYKKPKPFIDVLGRPMICHVLDNLNMP
                     DARFILLTRKEHFENEQETVNWIKSKYNVEFVLIDNLTEGAACTVLHAHKLIDNNTPLL
                     IANSDQIVDMNIAEFINDSENRNLDGSVLCFKDHDTKWSYAKIDGEGLITEIREKVVIS
                     EFATVGIYYFAKGGFFVKNAIDMIIRNERVKNEFYVAPVYNFGIQEGLKFGIFNININQ
                     MHGIGTPTDLNVYIDLVQRNK"
     misc_feature    complement(10945..11661)
                     /locus_tag="BF9343_3594"
                     /note="Pfam match to entry PF00483 NTP_transferase,
                     Nucleotidyl transferase, score -53.6, E-value 7.9e-05"
     misc_feature    complement(11617..11670)
                     /locus_tag="BF9343_3594"
                     /note="Signal peptide predicted for BF3694 by SignalP 2.0
                     HMM (Signal peptide probability 0.828) with cleavage site
                     probability 0.465 between residues 18 and 19"
     gene            complement(11673..12389)
                     /locus_tag="BF9343_3595"
     CDS             complement(11673..12389)
                     /locus_tag="BF9343_3595"
                     /old_locus_tag="BF3695"
                     /note="Similar to Pasteurella piscicida capsular
                     polysaccharide biosynthesis protein BcbE SWALL:Q8VW66
                     (EMBL:AB074293) (242 aa) fasta scores: E(): 2.6e-09, 24.18%
                     id in 244 aa, and to Pseudomonas syringae hypothetical
                     protein PSPTO0709 SWALL:AAO54251 (EMBL:AE016858) (240 aa)
                     fasta scores: E(): 9.7e-24, 31.48% id in 235 aa, and to
                     Pseudomonas syringae lipopolysaccharide biosynthesis
                     protein, putative PSPTO0706 SWALL:AAO54248 (EMBL:AE016858)
                     (253 aa) fasta scores: E(): 2.9e-20, 34.24% id in 219 aa"
                     /codon_start=1
                     /transl_table=11
                     /product="putative nucleotidyltransferase"
                     /protein_id="CAH09376.1"
                     /db_xref="EnsemblGenomes-Gn:BF9343_3595"
                     /db_xref="EnsemblGenomes-Tr:CAH09376"
                     /db_xref="GOA:Q5L956"
                     /db_xref="InterPro:IPR005835"
                     /db_xref="InterPro:IPR016873"
                     /db_xref="InterPro:IPR029044"
                     /db_xref="UniProtKB/TrEMBL:Q5L956"
                     /translation="MNVIALMAGDSNDFKEKGYTYPKYFLELDNKPLVQNIVESLKKID
                     CKITFIIRKEDNDQFFLGSSLKILAPFADVVCISGSTKGAVCTTLFAIDSINNEDEVLL
                     INGDQLVKYDINDIIADFRERNLDGGIVTFESVHPRWSYVCLDEQGLVVQTSEKRPISN
                     VATAGIYYYKRGLDLVESCFSVLKKDVQLNGSYYISSTFNELILRQKKVGVYKIDKKEY
                     ISFATTQMYENYINKK"
     misc_feature    complement(11703..12380)
                     /locus_tag="BF9343_3595"
                     /note="Pfam match to entry PF00483 NTP_transferase,
                     Nucleotidyl transferase, score -73.5, E-value 0.0014"
     gene            complement(12386..13018)
                     /locus_tag="BF9343_3596"
     CDS             complement(12386..13018)
                     /locus_tag="BF9343_3596"
                     /old_locus_tag="BF3696"
                     /note="Similar to Pseudomonas syringae HAD-superfamily
                     hydrolase PSPTO0708 SWALL:AAO54250 (EMBL:AE016858) (212 aa)
                     fasta scores: E(): 4.6e-49, 61.65% id in 206 aa, and to
                     Thermoanaerobacter tengcongensis predicted
                     phosphatase/phosphohexomutase TTE1983 SWALL:Q8R8L2
                     (EMBL:AE013150) (224 aa) fasta scores: E(): 9.6e-15, 34.05%
                     id in 185 aa, and to Clostridium acetobutylicum
                     beta-phosphoglucomutase CAC2614 SWALL:Q97FW2
                     (EMBL:AE007758) (215 aa) fasta scores: E(): 5.4e-13, 31.95%
                     id in 194 aa"
                     /codon_start=1
                     /transl_table=11
                     /product="putative haloacid dehalogenase-like hydrolase"
                     /protein_id="CAH09377.1"
                     /db_xref="EnsemblGenomes-Gn:BF9343_3596"
                     /db_xref="EnsemblGenomes-Tr:CAH09377"
                     /db_xref="GOA:Q5L955"
                     /db_xref="InterPro:IPR006439"
                     /db_xref="InterPro:IPR023214"
                     /db_xref="UniProtKB/TrEMBL:Q5L955"
                     /translation="MDKIKAVIFDMDGVLIDAKEWHYEALNKALRLFGFEISRYDHLVT
                     FDGLPTAKKLEMMTVERGLPKSLHQLINDMKQIYTMEYVYMKCKPLFVHQYALSRLKSE
                     GFRLALASNSVRVTIDMMMEKADLNQYLDFSLSNQDVKKSKPDPEIYITAINRLGLSPE
                     ECLVVEDNQNGVKAALASGANLLKVETINDVTYSNIINRINEIENNI"
     misc_feature    complement(12446..13009)
                     /locus_tag="BF9343_3596"
                     /note="Pfam match to entry PF00702 Hydrolase, haloacid
                     dehalogenase-like hydrolase, score 106.2, E-value 5.4e-29"
     gene            complement(13030..13650)
                     /locus_tag="BF9343_3597"
     CDS             complement(13030..13650)
                     /locus_tag="BF9343_3597"
                     /old_locus_tag="BF3697"
                     /note="Similar to Pseudomonas syringae hypothetical protein
                     PSPTO0707 SWALL:AAO54249 (EMBL:AE016858) (204 aa) fasta
                     scores: E(): 1e-26, 39.51% id in 205 aa"
                     /codon_start=1
                     /transl_table=11
                     /product="conserved hypothetical protein"
                     /protein_id="CAH09378.1"
                     /db_xref="EnsemblGenomes-Gn:BF9343_3597"
                     /db_xref="EnsemblGenomes-Tr:CAH09378"
                     /db_xref="GOA:Q5L954"
                     /db_xref="InterPro:IPR017946"
                     /db_xref="UniProtKB/TrEMBL:Q5L954"
                     /translation="MEIIAHRGFWNKESEKNTLTAIKRAIDNGYGFETDYRDNNGTIVI
                     SHNMPLGNEPTAEEIFRLYRDSGTESTLALNIKADGLQELLKDMLNTYQIKKYFLFDMS
                     IPDTIDYILDNMNIATRHSEYEKEFPFYSQSSYVWMDCFKSEWISWGNLEEHLKSGKKV
                     CIVSPELHRRPYKEVWNKYASFNHANLMLCTDFPMEADFFFNK"
ORIGIN
        1 aaataggaag tataatagcc ccaacaccaa gatgctccct aataaatacc catatccata
       61 ctcccgtaac agcaaatatc ctactagaac tacggtttgc accgacatat aggtcaatgc
      121 cactgccacg tgtggtatct tcagctcatt ggccatgatc tgatacaaat gtttcctgtg
      181 aggcaaacca atattttcat gtagcaacaa tcggtgtacg atcgtcaaca cactatccac
      241 tccgtacaca acaagcaata caagccagct gaaatcttta gtttgaaaaa tcaaactccc
      301 gatcaggaac aagactacaa aagctatact gaccgaaccc acatcaccgg caaagcattt
      361 cgctctctta cggaaattaa agaagtcaaa caccaacaca gaacaaatca tcgtataaat
      421 aaaactctgt tctgtgaaga agatcacttc tgcattcaca tatgccaaag aaatcaggat
      481 aaccaatgaa tatccgccgg taatgccgtt aatgccatcc ataaagttat aggcattgat
      541 aatccccgta cagacgatca gagcgacaag caacgtccac caaggcaagc taaacaatcc
      601 ccattgatag aacatcaggg ccattgccat aaaatggaag actaaacgca aaccttgcga
      661 agtagaacgg atatcatcta caaaactgat aaaagtgatc aaggtcaaag ccagtataaa
      721 ccaagggtat tcaaactgat tcgtcaggaa aaaagtcaat gcacccaaat agaaaatgat
      781 tcctccacct ctcagagtaa tacgggtatg cgaactccgt tcattcggct tgtcgataat
      841 attacattta tcagcaatac gaaaataaaa aagttctgcc agaaatagca gaactaatat
      901 aagaatataa tacatgtaag ttaaccgttt ttataaatca gataaaacca aaattgaaca
      961 caaagaaaag ctacgagaat aattacaata agtattccca aaatccagca aataatagtc
     1021 ataattcaat ttactctatc cgaaaactct ctaacacatt cacaggtttc catccaagtt
     1081 cccgtactgc cttttcatta ctaaaagtca aagagttcgt aatcttacgg agcttcaaag
     1141 aattaatcgg agctttttct cccaaacaat caccaacaac tgccatacct ttagcaaaat
     1201 aataaggaat agacaaaggc aattttttat ttaactgatt acatataatc tcttccaact
     1261 cacgaaaact aggttgataa gtatcgcaaa cattatatat ccctcctttt tctactaata
     1321 aaggaacaag attggcaata tcctgcacca tcaaaacact cttccgggct tttcctcccg
     1381 caatactcag atacttgcca ctcttaatac catggatcat tgtccctaaa tttcccggag
     1441 gattaggccc ggcaattaaa gaaggacgaa gtatactcaa ttttacattg tgcatactac
     1501 accacccttc gagatatttc tcagctttaa tcttacttaa agcataaggg ctagttccat
     1561 tcaacgaata ttcttcggta atattctcac caaaatcaca gccataaaca gcaacagtac
     1621 taatgaaaat gaaggcctta ggcgtacaaa aattttccaa agccgtacac aaattctttg
     1681 taccttgcag gttgatatca aagaaggttt gtttttctac ctccgtttta ggtattgaat
     1741 gggcttttcc tgcagcatgt aaaacaacat catatggcat atttagtgtc gggatttctt
     1801 gcgctatatc cactttgtaa ttatcctgca gagcaagtcc catagtatct atcttatatt
     1861 tttcttttag caaaaaacaa atatttctcc ctagaaaacc agaagcaccc gtaaaaagaa
     1921 gattcatttt aaatatttaa aaagagattt attcaaatct gacaatgagt aatacaaact
     1981 taaccagatt gtttttttct gttccactct ataaatatgc caaatccatt ttataactct
     2041 caatttattt gaagagacag aacctttgcg tattctatac aacgccaaac aaatatttgt
     2101 atttatagca ataaaacctt ctttgagaat atctaaccaa agattgtagt cctcatgtcc
     2161 aataaactta aaataacgtt tccctatttt ttgcgtatca taaaccacag ttaaacatcc
     2221 taactcattt ccacacaata aagatttata atgatgatag ggatctgatt taacgattct
     2281 tcccgtacga tttccttctt cagatatttt ctcataatca gaatagacaa ttgcaacatt
     2341 atcattaata aataaaggaa gttgagtaga caatttatta ggaagccaaa tatcatcgct
     2401 atctaaaaat gctataaaac gtccttttgc agcttgtatc ccgacgttac gaggaagagt
     2461 tggtccccca gaaggatgct ctgttttcaa ataataaatt cgagaatccg tatccataaa
     2521 ttccattata attttcacag aatcatcatt tgaacagtca tcaattatca acaactccca
     2581 gttaacatag ctctgtgcta tgacagatcg gatcgtttct cgtatagtag ccgcagaatt
     2641 ataacaggga gtaataatag aaacaagttc attcattatt caacaatatt aaacaaaaac
     2701 acaagacaga caaaacttta ctaaaaaaaa gctgtattac gtgacagttt tatggcccct
     2761 ttaatggacc ctggaattct agaagcaaaa agtaagaaat tatacgagaa aggagaagac
     2821 aaataaatag atacatatgc ttttattagc ataaaagtat cccaacacaa ttgtcctcgt
     2881 ttaagaggtc ttcttgaagc agagccagct ctctctctca cataataagt agtatattct
     2941 ttcgtaaaac gaaatcctcc aatcaaatcc gatatttcgg tcataaaaag cgcatcctct
     3001 ccatttttaa atcgtggatt aaaccttcta tttccaataa tatctcgatg tatcaattta
     3061 gcgacaggaa atgctaatat agctcgattt ctaaacaaag aatactgaca ctctctttgt
     3121 tgaataattc ggcaagcaaa aaaattatcc tccttctctt ctatcgtttt tctaaatgta
     3181 tgcacattac taactccaac tatattccga gaagatattt tacacaattc ttcaaggtaa
     3241 tcagaagaga caatatcatc atcatcaacg aaaccaatat attgcccttt tgcagcatca
     3301 atgccaagat tcctcgcatt agatacgcct gcttgatcag tttttatcaa cctacaatac
     3361 aagccagctg gtttataagc aaatatatct aatatcatat ccgtgtactg tgtgtcaata
     3421 tcaccattca atacaactat cacttcatat aaatagtgaa acatcgtttg gttaaataac
     3481 gaaaaaagac actcctcaaa ataagttttt tgaggtttaa atgtgggaac aataatagat
     3541 aaaagcattg tcattagatt atagatgctc agtaatctaa ttctaaatca accacgacct
     3601 ataaggcaga taaacatcct tccctatatt tatatatcta aagaaaaaat agattaccat
     3661 caaattcaat ataaaaagca ccatcattct attcttaaca gaaaagaaca gaaacaattg
     3721 cgagataata aaaattgtcg acagttgaaa tatgagtaca gtcctctgct gaaatacata
     3781 cgtttggaaa aaggcataat aacaaataat actcaataca aacagattaa aaaccagatt
     3841 aaatgagatg tttttttgct ccaatttttc ccgaagcctc aaacacatta aaagtaatat
     3901 aaatttttca gcaactgcta tatttatctt accagtcata ccgccccaca cgtctgattc
     3961 cgtatagctt gttaaactgc tctgtataaa aggaggaaaa aaactaagaa tagctcccat
     4021 ccagtcaaag aaagacaata gtacagaaat aaatacaact gtacacaaaa aaatgttact
     4081 atatcttctg ttaataacaa aatacagagg aagaactatt aataaactcg aatgaaaaag
     4141 agaggataat atattgatta ataaatactt tattattttt ttatcttcta tatattttaa
     4201 agaataaaag aagatagata tagctattcc ttgtctgaca aacatcatat taaactgcat
     4261 atacccataa cgcatataaa gtaatacagc taaaaaagga agtagtgtat accttttttg
     4321 aaatacaaaa aataaggaaa taacaactat tgacgataat aaaaagactt catttatact
     4381 cccaccaaaa gatttaatta cactattaaa tagaatgtaa ccaggttcca ttctgaacaa
     4441 aagaaacata ccgttatcat tccataaatc gcttactagt ggaattttat caaacacctt
     4501 tgtatattcg ccccaatcat cacctgtttc aaatcgtgtt ccaacaaata atattagaat
     4561 aaaggaaaga aaaaataata atattttctt tttaaaaaca tttaaattag aaaaatcaaa
     4621 aacactgaaa aacacaacta ataatataat gaaagcgtaa ggtatcattt ctttatctga
     4681 atcttataat acaagaattt aaaaagatac ataataaaat agaagcctct gctctctgag
     4741 taccatctcg acaaactcaa ccctctttta ttcactaaga aagcaatata tttataattg
     4801 ctagcccctc tataatgaga caatattttt gtaaggtgag catttatttc tgatggtctt
     4861 attgttaaag cttgatttct aaatctatta ttatccgaaa tgatgaaatg caaatacaac
     4921 tctttttccg tataatctat ccctttattt ctaaaaatat ctttataaat tgacttgtga
     4981 acatcaaaac gcgactgaaa atttttattt gcttgtctag tgacacttga ttctaatatt
     5041 ctatatttca ataatacttc cctaatatta gaaatcttag tatatttaac tgcctgacac
     5101 caaatagcat agtcctctgc atgcaaatat cggtcatcat aacgtaactt atatttatct
     5161 acaatagatt tacggataat aacggatgga tgagctaaac aagtagaaaa taatagaaaa
     5221 gcttcattca cattgacatt acttgggaat ctttgtactt tccgctttat tgtatcacca
     5281 aagatctcaa tataagagcc acaaacccca acttcaggct ctctctccat aaactcgact
     5341 tgtttttcaa ttctatttgg caaactgatg tcatcagcgt ccattctaac gatatattta
     5401 ccaatagatt ccagtaatcc cctatttaat gaataaacaa gacccttatt ttcttgatta
     5461 tttaggactt taattctttc atcatcatat aattccaata tctccgaaaa attatccgag
     5521 gagccatcat ttattataat gaattcaaaa ttcttataac tttgactaag tatactattg
     5581 atagcgtctt ttaaaaactc ccctccatta tataccgaca ttacaactga gacaaaagga
     5641 ttactattca tacacaaatc caatcagaag gaataatatc acttacttgt actctgtcat
     5701 cattaatcca cttcccaggg gcaataacaa tcctctcggg atttgtgtta agccaagctc
     5761 cccaccaact aaaagaactg tttgctatta tattatgttt gcaataagtc attaaacaca
     5821 tatcccaata cgattcttct ttgttattcc aatctataat atggcaatta ggtattttta
     5881 gatgatcctt acaccacaca gtatcatctg agaaaacaaa aaattttggt tctgagactt
     5941 tgctttgaat tatatttatg gctttattat aataagcaga agtacaaata ttagaataag
     6001 caggattatt aacatagtct cctaatcgaa catgaaggct cactgaattt gaattttgca
     6061 tttgcttctt tatgaactca ttcttatcgc ttaaaacttt agaaaaatga aactgtccac
     6121 gaatagccgc ttctatattc gtaaaatatt tatagctttg ccaatatcct atataatatt
     6181 tatcacacga taatgatata gcattctcat caaaacacaa atatggctct acatattctg
     6241 ttttttttcg tttcaatagt ttacgcaaca cccttatcca tatttcactt ccctggtaag
     6301 acaattttat tctttctcgg atggacgcct ttagatattc aacatgaaaa actttatcaa
     6361 gttcaaatcc attgtgcgta taagcaccaa acgaagaagt gtctaatttt acattaacat
     6421 acttttcctt taatgctaaa taaaatgcaa actgaaacat ttggttgcct aatccaccaa
     6481 ttatttgtac tattttcata caacatctaa aaaacaaatt aatctaacat ataaaatggc
     6541 tcacatataa ctaataaaac aacctgtata ttctatttct aattctatca aaaacactaa
     6601 gccgcatagg agaaagaagt aatttttcct tatctaactt agcaggtatt gaatccagtg
     6661 tactcgaaat taaagaaaac atattatatt tatctaaaat tttgtctcgt gcatgacaaa
     6721 tattctcata ttgcttctca taaacattat tatctattat tttttttata gtctgcttac
     6781 tttcatcaaa attcctaata tcaatcacag ccatttcttc ctttgaaaaa aaatctccaa
     6841 tatgtggatc accaaaatat atcggatagc atcctgacaa gaaagtatca gccaatttct
     6901 cagtccaata atacggatat gaacagtttt ctattacaat ggcatactta tattgtacca
     6961 tcacttcata tttataatca acattagtaa agccagaacc atatatatca atcaaatcag
     7021 gcatttcctc ttgcaatttc aacgcaaact taatgcgttc aatatgcccc ttagatattt
     7081 ttttattaga agtaaataag cagattttat ttttcctctg taatgttggt ctatttttca
     7141 aaaaatcata atctattaat aactcttctt tttgtttgtc attatagaaa ttgtaatata
     7201 gcatccaagg taatgcagga taagataagc aggcattatc tctttttaat acactggatt
     7261 ggcacgtata aacatgccca aattggttta aatatttacg aggataaagc ttaacatatg
     7321 gaggttctcc tgtaaataaa catatatttt gcttacagca catcaaacga agagaatatt
     7381 caatgtcatc taataccaca acataatcgt attcttgctc tggttcttta gtagatataa
     7441 taaactcgta atttccccaa ataggaactc tattagggaa ctgcctttca acaggaattt
     7501 tggtatttat aggaatgaat acttttttca tatagaatca cttattacaa caaacaattt
     7561 caacgctcaa tagaataaat cttcctttct cttacgatac tctattttat atttatccat
     7621 atcaaatcca actaaatttt gtagatagtc ttttttttct tttatcaagt catcatccca
     7681 atcccaccac ttgatttcca acaacttttc tcttacttca aacggaaacc tccattttat
     7741 aaatttagca ggatttccac ctactatagc atatggtgga atagatttag taacgacact
     7801 tcctgctgca attacagcac catcaccaac ctctacgcct cgcaagattg tgacgttagt
     7861 accaacccat acatcattac caattttaac ccaataatct tcgaaagaac tgatccctgg
     7921 tggcattatg tgatcattat ctttataaac gaaatcgcaa attaaaaaat tagtatgtat
     7981 atgatctctt attcctattt tagcccaaga agaaatattt gtaaaattac cgacaagagt
     8041 atctataatt tcggcatagc ctccaatacc actatgttta ccccatttag tatttataat
     8101 gcaaatatta ttacctccat aaaaataatt agatgagtca aaagagtttt tattttttct
     8161 caacttaaat ctaatacttg ctctatataa aacaagcaaa attagattta tacacttctt
     8221 aatatttagc aatatcttcg acatagtttt ctttattaat atcaatggaa tacatgccat
     8281 ataatttaat cgtattttct atccagttat cacagtatgg tgcatcattt ggtgacttat
     8341 cctttaaaaa agaaacacaa ctattattat taaaaactat attagctttt tctcttactc
     8401 tctttgacca ttcaacgtcc tctccttcac cccatcttaa tttctcatca agcagattgt
     8461 taataaaaaa atctttcttc actacaaaat aggtaccact aatatattga tattttttac
     8521 actgaatctt atatggcaat agagctggcc ctatgttagg ataatcatag actaaccaat
     8581 ccctggttct attcccattt ttcaatgtga ttctattcat gcaaatgtca aaatctcgac
     8641 caaactcttc aaaacctact ttccagcccc tatttagcga cacataatca tgcattatca
     8701 ccagtttatt ataaatagca gctttagcac ctatgttctt tttaattgtt atccaaccgg
     8761 ctaaaaatgg aaggctataa tatgatatat acttaatttt attatttaat tgaggataat
     8821 ctctattttg accaataaca ataatctcat agcgatcctc accaaattcg tctaaaatac
     8881 ttttaatagt aaaattcagc atttctttac tctttccatc tgttataatt atgaatgacc
     8941 acccttcatg atataaatca ttttccatac gagagtttat attacatcgg cgttcgatat
     9001 agtctaagaa ataccttata aaaacagtat gttgaataat gttctttaaa aaactaccta
     9061 gtattttcat cgatgattat ttaaattatt tataatgaca tttttacttc tattaaaata
     9121 aaacagcata cgttgaaact cctctgtttt ccggtatata atataattca tcacgctaat
     9181 cacagaaata caaacaaata atttagcaat aaaaaaaatt ataccattcc ccaaaaaaga
     9241 acaaattaca aatgttataa aatagccaac aagcaaaaca acaattctca acaactgcct
     9301 ttttatatat ccggtagata tattaccaaa atattcttct ttcagaactt tataacgacc
     9361 aatccaaaac cccaacatac ctataatagt tccaatatat accccagcta taccatagct
     9421 attaactaac ataatcgata caaataagct taacaacgca cctcccaaat tgtaaaatct
     9481 atcaatttca aatctgccaa aaacctccct ataacacgaa acaaaatgag aggcaaaacc
     9541 aatatacaat ttcatagata tcaatattac aatgaaaagg gacaatacgt atttctcgcc
     9601 tatccaaatg gatataaaag gatttattaa atttgcaaaa caaatagaaa ctgttgatcc
     9661 aataataaaa gaaagtaatt caaacattct gaatagttta aatccttccg ctttatcttc
     9721 agaatacaca tagtttccta tgctgccttg caaaggtgaa aatatctttg agaacgcagc
     9781 ggcaatagct tctgatatca atgtataatt tgctaacatt gcgacagact ttacccctaa
     9841 cgatgaagat aaaaccaaac tattagtact gccaaaaatt gtaccagcta ttttagacat
     9901 atatacattt ttcatatcca tgaaaaaatt tctctctcta aaatcaggaa tactaacctt
     9961 gacttctttt gagtatggat atttcgtata agacattcta gctataatga tattggcaac
    10021 aaatacagaa atagtctgaa taatcaaata tgcgatatag ctttgagtag caataattac
    10081 aataaaccaa ctcaaatatt taaaataatt agttattgta tcaattttag tacatacata
    10141 ctcacattga tcaactttaa ataaaagcct tctataagag aagcaataag aaccaaccat
    10201 agctattcct ctaataagat atattactat aatatagttc caatcaaacc ctttggactt
    10261 aattaaaatg ggcaacaatg ggattaaaaa gatgctaatt atccccatag caacagctat
    10321 gaatagatac atctttttgt acattgacat taaaacagat acttcccttc tattattctc
    10381 cgaaaaagct ttatacagta aatatgatat tagcgaccct gtccctacat ctaccagtgc
    10441 catcagagaa aacatattct caaacacact gtcaagcccc aaatattcaa tatctatata
    10501 ttttaaaaat acttttcgca atattaagga caaaataaac aaagaaccgt atgaaaagac
    10561 agagtaaaat atattcttta aagctttatt tgtcctcatc tcaatttatc actgataatc
    10621 acaggcagta tttatcatca tttgctccag gtaatttcac aactacattc tgtgtaccat
    10681 tttctagaca ctcaaaatca gtcgcctcat tgggctccat aactactata tctcctttgg
    10741 agtattctat tccgttcatc ttcaccttac cactgacgat aacagttatt tccgtagcaa
    10801 ttttatgata atgcttctct tcatagtcac ctttgttata agacttaact gctacttcaa
    10861 catcgttcgt tcttaaaaga gttggttcaa aatttcctat aaaccaacct tttatcatat
    10921 cctcaagttt cgctgttttc atttatttct ctgcactaaa tcaatatata catttaagtc
    10981 tgttggagtg ccgattccat gcatttgatt tatgtttata ttaaatattc cgaatttaag
    11041 tccctcttgt attccaaaat tgtaaaccgg tgcaacatag aattcatttt ttacacgttc
    11101 attacgtata atcatatcaa ttgcattttt tacaaaaaaa cctcctttcg caaaatagta
    11161 gataccgaca gttgcaaatt ccgaaataac aactttctct cttatctcag ttattaaacc
    11221 ttcaccatct attttggcat aagaccattt tgtatcatga tctttaaaac acaacactga
    11281 accatctaaa tttcgattct cactatcatt gataaattca gcaatgttca tatccactat
    11341 ctgatccgaa ttagcaatta ataacggagt attattatca ataagtttat gagcatgaag
    11401 cactgtacag gctgctcctt ccgtcaaatt atctattaac acaaattcga cattgtattt
    11461 tgattttatc cagttcacag tttcttgttc attctcaaaa tgctctttac gagttaaaag
    11521 aataaaccta gcatcaggca tattcaagtt atccaaaaca tgacaaatca taggcctacc
    11581 taatacatca atgaatggct ttggcttttt ataaccggct tgtgcgaagc gactacccgc
    11641 tccggccata ggaatcacaa tattaatcat ctttatttct tgtttatata gttttcatac
    11701 atttgagtcg tcgcaaacga tatatattcc tttttatcaa ttttatatac acctactttt
    11761 ttttgtctca atatcaattc attaaaagta gaacttatat aataactacc atttagctga
    11821 acatcttttt ttagaaccga aaagcatgat tccactaaat ccaagcccct tttataataa
    11881 taaattccag ctgttgcaac attagaaata ggacgttttt cacttgtttg caccaccaag
    11941 ccttgctcgt ccaaacaaac atagctccat ctgggatgaa cggactcaaa agtaactatg
    12001 ccgccgtcta agtttctttc tctaaaatca gcaataatat catttatatc gtacttcacc
    12061 aattgatccc cattaatcag caatacctca tcttcattat ttattgaatc aatagcaaac
    12121 aaagtggtac atacagctcc ttttgtggaa ccagaaatac aaacgacatc cgcaaatggt
    12181 gctaaaatct tcaatgaact tcctaagaag aactgatcat tatcttcctt acgaataata
    12241 aaagtgattt tacagtctat ctttttaaga gactccacaa tgttctgtac aagaggttta
    12301 ttatctagtt ctaaaaaata tttaggataa gtatagcctt tctctttgaa gtcattactg
    12361 tctccagcca tcaatgcaat tacgttcata tattattctc tatttcattt atacgattaa
    12421 ttatattcga gtaggtgacg tcattgattg tctctacttt gagaagatta gctccactgg
    12481 ctaaagctgc tttaacccca ttctgattgt cttccactac cagacattct tcaggagaca
    12541 aacccagcct gtttattgcc gtaatataaa tttccggatc aggtttggat ttttttacat
    12601 cttgattaga taaagagaaa tctaaatatt gattcaaatc tgctttctcc atcatcatat
    12661 ctatggtaac ccgtaccgaa ttcgaggcca gtgccaaacg aaaaccttcc gattttaagc
    12721 gtgataaagc atattgatga acaaaaagag gcttacattt catatatacg tactccatcg
    12781 tatatatttg cttcatatca ttgatcaatt gatgtaagct tttcggaagc cccctctcta
    12841 ccgtcatcat ttcgagtttt ttcgctgtcg gcaaaccatc aaatgtaacc aaatggtcat
    12901 atctagatat ttcaaatcca aaaagcctta aagccttatt caaagcctca taatgccatt
    12961 ctttggcatc aataagaacc ccatccatgt caaatataac agccttaatt ttatccattt
    13021 ttacattatt tatttattaa aaaaaaagtc agcttccata ggaaaatctg tacataacat
    13081 caagttagca tgattgaaac ttgcatactt gttccaaact tctttatatg gacgtctgtg
    13141 caattctggt gagacaatac atactttttt accactttta agatgctctt ccaaattacc
    13201 ccagctaatc cactcacttt taaaacaatc catccaaaca taagaggatt gactgtaaaa
    13261 aggaaattct ttttcatatt ctgagtgccg ggtagctata ttcatattat caagaatata
    13321 atctattgta tcaggtatag acatatcaaa taaaaaatat ttctttatct gatatgtatt
    13381 tagcatgtcc tttaataact cttgcaggcc atctgctttt atattcaaag ctagggtgct
    13441 ttccgtacca ctatcacgat acaatctgaa aatttcctca gcagtaggct cattacccaa
    13501 cggcatatta tgagatatta caattgtacc gttattatct ctataatctg tttcaaagcc
    13561 ataaccatta tcaatagcac gcttgattgc agttaaggta ttcttctcag actctttatt
    13621 ccagaatcct ctatgagcta ttatttccat
//
