LOCUS       MN148381               24890 bp    DNA     linear   BCT 18-JAN-2020
DEFINITION  Acinetobacter baumannii strain BAL_204 KL55 capsule biosynthesis
            gene cluster, complete sequence.
ACCESSION   MN148381
VERSION     MN148381.1
KEYWORDS    .
SOURCE      Acinetobacter baumannii
  ORGANISM  Acinetobacter baumannii
            Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
            Moraxellaceae; Acinetobacter; Acinetobacter calcoaceticus/baumannii
            complex.
REFERENCE   1  (bases 1 to 24890)
  AUTHORS   Kenyon,J.J., Hall,R.M., Holt,K.E. and Baker,S.
  TITLE     Sequence of the Acinetobacter baumannii KL55 capsule biosynthesis
            gene cluster
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 24890)
  AUTHORS   Kenyon,J.J., Hall,R.M., Holt,K.E. and Baker,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JUL-2019) School of Biomedical Sciences, Queensland
            University of Technology, 300 Herston Rd, Herston, QLD 4006,
            Australia
FEATURES             Location/Qualifiers
     source          1..24890
                     /organism="Acinetobacter baumannii"
                     /mol_type="genomic DNA"
                     /strain="BAL_204"
                     /host="Homo sapiens"
                     /db_xref="taxon:470"
                     /country="Viet Nam"
     misc_feature    1..24890
                     /note="KL55 capsule biosynthesis gene cluster"
     gene            complement(1..2187)
                     /gene="wzc"
     CDS             complement(1..2187)
                     /gene="wzc"
                     /note="protein tyrosine kinase; involved in capsule
                     export"
                     /codon_start=1
                     /transl_table=11
                     /product="Wzc"
                     /protein_id="QHE90298.1"
                     /translation="MNQQNTNAEDTIDLKELFFSLIAQWKLIALCVILSVVCALLYLR
                     VTPDTYSVDALVQVEDSKGASAALLGDLSQMIEQKSPAQAEIEILKSRLVLGSVIKDL
                     HLNIQVSSTENTLTHRLLSDTEYKTEYTKKSVLFKDNLKSFEVREFEVPAYYLDKNLL
                     LNFDKQSLRLTDPDTEEVILTVPLNQANHVAGPHGLWKIAIFTKDQFDATYNITNLSL
                     PAAVNALSANYAVAERGKLTGVLGLNYQGQDKEHITKVLNAILATYSAQNIERRSAES
                     AQTLKFLDEQLPDLKKQLDDAERQFNKFRQQYNTVDVTKESELYLTQSITLETKKAEL
                     EQKQAEMAAKYTAEHPAMREINGQLAAINKQIGELNSTLKQLPDVQRQYLQLYREVEV
                     KTQLYTALLNSYQQLRIAKAGEIGNVRIVDTAIEPVKPIKPKKLLVLILSVFVGGFIG
                     TLIALLRNMLRTGIKDSGQIENELDLPVYATVPRSPIQESRIKILKKKKSIPILAVKN
                     SDDIAIESLRSIRTAIHFALANAKNNIIMIAGPSPEVGKSFISTNLATIFAQGDKRVL
                     LIDADMRRGYMHKYFDVDVKPGLSELLSGQADLSQVLHKTQVTNLDVITRGKSPTNPS
                     EILSSNQFKELLEQLQSQYDHIIIDTPPVLAVTDGIIISQYTGVNLIVARYAKSQMKE
                     LELTVNRFEQAGVKVNGFILNDIQRASAGYGYGYNYAYAYKAQKED"
     gene            complement(2207..2635)
                     /gene="wzb"
     CDS             complement(2207..2635)
                     /gene="wzb"
                     /note="low molecular weight protein tyrosine phosphatase;
                     involved in capsule export"
                     /codon_start=1
                     /transl_table=11
                     /product="Wzb"
                     /protein_id="QHE90299.1"
                     /translation="MQIKNILVVCIGNICRSPMAEYLLKQQYPQLNIESAGISGLIGH
                     QADEKAQLCMQRLGIDMQPHIARKLNAELIKKADLILVMSNNQLKHIEQTWPFAKGKT
                     YRLGHWQNKNVPDPYRHDQAVFDETCQLIQQCVTDWKPYI"
     gene            complement(2640..3758)
                     /gene="wza"
     CDS             complement(2640..3758)
                     /gene="wza"
                     /note="outer membrane protein; involved in capsule export"
                     /codon_start=1
                     /transl_table=11
                     /product="Wza"
                     /protein_id="QHE90300.1"
                     /translation="MHKGSRVKYCQFFSVLALSLSAASCAVTSGLQTYDIPSEGVYKT
                     DLGTTVNVVKISQETLPAIQPAQIDYQRDYASLFKNQQSIYRLSPGDVLSIQLWAYPE
                     ITPPVNNISNEQSIQANGYPIDQSGYIQFPLVGRYKAAGKTLAQVNRELRSQLARFLK
                     NPDVVVRVVSYEGQRFSVQGSVTKGGQFYLSDQPISIYTALGMAGGVTTTGDNTYIQL
                     IRNGRTYNLNTIDLEKAGYSLHKLLIQPNDTIYVSTRENQKIYVMGEAGKSQALPMRD
                     QGMTLSDALGESLGINPTSGSASKIYVVRTNPNDRTTEIYHLNLMSIGDFGLANQFRL
                     RSNDIVYVDATGLTRWQRVINQIIPFSNALYNIDRLGQ"
     gene            4096..5370
                     /gene="gna"
     CDS             4096..5370
                     /gene="gna"
                     /note="UDP-N-acetyl-galactosamine dehydrogenase"
                     /codon_start=1
                     /transl_table=11
                     /product="Gna"
                     /protein_id="QHE90301.1"
                     /translation="MQIAKLKIAIIGLGYVGLPLAVEFGKKVPVVGFDIYQKRIDELK
                     NGQDHTLEVSPEELKQAVHLNYTAHLDDLQDSNFFIVTVPTPIDDFKQPDLTPLIKAS
                     TSIGQVLKKGDVVVYESTVYPGATEEVCIPVLEKVSGLKFNQDFFAGYSPERINPGDK
                     QHRVTNILKITSGSTPEVADYIDEIYNLIIEAGTHKAPNIKVAEAAKVIENTQRDVNI
                     ALINELALIFNKLGIDTEDVLKAAGTKWNFLPFRPGLVGGHCIGVDPYYLTHKAQSIG
                     LHPEIILAARRLNDRMGEHVATQLIKEMVKQRIQVVGARILVMGLSFKENCPDIRNTK
                     IVDFINALKEYDLDLDIYDPWVNDTEVQHEYGLAPIKELQQGLYDAIVIAVAHNQFKS
                     MSVEEFHTLGKEKYVLYDLKYVLDKADSNLRL"
     gene            5400..6263
                     /gene="gtr110"
     CDS             5400..6263
                     /gene="gtr110"
                     /note="glycosyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="Gtr110"
                     /protein_id="QHE90302.1"
                     /translation="MNNNKIALVVIVYGKALEDAMTIQSLLSFEEKLEHLLIVNNGPA
                     VIDENSAVLTSLAQKHHHVVLENQVQNKPLSWIYNDFIQQYDADYYVLFDDDTEINPE
                     YQRKIFIMQGVDIELPKIISMNDKAQYYPLVDGVIEQKDGIISNAKEIFSIGSGLVIS
                     KDIKQYFIENKIELFDSHFALYGVDFSFFRKINHIAKQKNIIFSISSNTYIKHSLSRT
                     EKETNAWRDKERLYDLVLTLKYYYSYAELRILKLFFKKILGGKIKDALLILSTAFNGA
                     HPRCMNKVLND"
     gene            6256..7209
                     /gene="gtr79"
     CDS             6256..7209
                     /gene="gtr79"
                     /note="glycosyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="Gtr79"
                     /protein_id="QHE90303.1"
                     /translation="MIEVSKVLEDRIDIALATYNGEKYITELLDSLDQQTYQNFIVHV
                     CDDGSKDRTIAICEAHSLFKKGKLEIHEKTGGNGASRNFIRTLSYCKNPYIALCDQDD
                     FWIPTKLEKMLVKTQHEEGSEKKPTLIFSDLQIVDEKLHILSPSYFAVSSKSNQCSTP
                     FDFLLSNHVPGCTMMFNQSLKQVFEPIPQEFRMHDWWIILIAAFWGRVIYLDESLIQY
                     RQHGNNTVGAVGMDKPTLIQKLRTVLLYKTILLKVDMVRKSFLPYIQQKEIQQEKLSL
                     EQKKFIDLLQRRLPLSKRLQIFSKTVTGEDRLLSFLVWCLL"
     gene            7206..8453
                     /gene="wzx"
     CDS             7206..8453
                     /gene="wzx"
                     /note="oligosaccharide-unit translocase"
                     /codon_start=1
                     /transl_table=11
                     /product="Wzx"
                     /protein_id="QHE90304.1"
                     /translation="MSKAINKEVFYLYIIQIANMVIPLLSFSYMANILGLVGFGQVSF
                     YQTVSFLAAFFIDFGFNMSAAQKMSISLDDKSKMDELYSNVQSIKFFIFLVVSVLGGL
                     SILFLPLSHIDATLLFIGILSAFSTILLSGWVFQGLGRNSVLAFFSVVGRVVSVGLIF
                     LLIHQKSDVLLAVIIQVAISFSIGLAAIIYFYRKNVVTFRIKTISIFKMRQLSEDSYH
                     NFTASLFTLGFTYLNPLVVKFCFGDAFLGLYALADKLAVILKQFFTPVTQAYYSRMCI
                     LSHEKKYQELIQNAKKVAIFFATISTLAFFGNLLIGNYIYNFLFGPEYKIVSLLSIMI
                     MTQFIVSMAMVLVNLIIIPTENSRILKKYYLIGLIFHFGYFYFFVKYLHIYGVASAIL
                     LTETILTLSFFMYVRKYFSKVLT"
     gene            8470..9633
                     /gene="ugd4"
     CDS             8470..9633
                     /gene="ugd4"
                     /note="UDP-glucose 6-dehydrogenase"
                     /codon_start=1
                     /transl_table=11
                     /product="Ugd4"
                     /protein_id="QHE90305.1"
                     /translation="MKITVVGTGYVGLSNAMLFSKQHEVTALDIDATKIDKLNQGISP
                     IHDDLIQEYLTDNSNFKATLDKQSAYMDAEVIIIATPTNYDEASNYFDTSSIESVLED
                     LSHLKSNAIIVVKSTIPVGFTERMKVTYPTLKIVFSPEFLREGKALYDNLYPSRIVVG
                     STSEVGKLVGQLFKNASLRPDVDVLQMDATEAEAVKLFSNTYLAMRVAYFNELDSYCA
                     SRGLNSKDIIQAVGLDPRIGAHYNNPSFGYGGYCLPKDTKQLLANYQDVPQNLIGAII
                     QSNTTRKDFIAEQILARKPKVVGVYRLVMKQGSDNFRQSAIQGVMKRLKAKGVEVIVF
                     EPSLNESTFFNSRVLTDFDSFKQESDVIIANRMVSELEDVIDKVYTRDLFGEN"
     gene            9652..10719
                     /gene="rmlB"
     CDS             9652..10719
                     /gene="rmlB"
                     /note="dTDP-D-glucose-4,6-dehydratase"
                     /codon_start=1
                     /transl_table=11
                     /product="RmlB"
                     /protein_id="QHE90306.1"
                     /translation="MKILITGGAGFIGSAVVRHIIQNTEDEVLNVDKLTYAGNLESLI
                     SVENNPRYQFSQTDICDRAALDKLFETFQPDAVMHLAAESHVDRSITGPYAFIETNVI
                     GTYQMLEASRAYWLSLNDEKKAAFRFHHISTDEVYGDLEGTTDLFTETTSYSPSSPYS
                     ASKASSDHLVRAWNRTYGLPVLVTNCSNNYGPFHFPEKLIPLMILNALQGKSLPVYGN
                     GQQIRDWLFVEDHARALYTVVTQGTVGETYNIGGHNEKANLDVVHAICDLLEELAPHK
                     PEGVAQYKDLITYVKDRPGHDVRYAIDATKIKEELNWVPKESFETGLRKTVEWYLNNK
                     EWVEHVQSGEYQSWLNKQYQG"
     gene            10722..11615
                     /gene="rmlD"
     CDS             10722..11615
                     /gene="rmlD"
                     /note="dTDP-6-deoxy-L-lyxo-4-hexulose reductase"
                     /codon_start=1
                     /transl_table=11
                     /product="RmlD"
                     /protein_id="QHE90307.1"
                     /translation="MKILLLGKNGQVGWELQRALAPLGDVIALDRHGLDSLSGDMTQP
                     QAIYDTILAVQPDVVVNASAYTAVDLAETEQELADIINHQTVKAAAEACQKTNALLVH
                     YSTDYVFEGTGTTAFVETDAIAPLNVYGKTKALGEQAIVDSGCRYLIFRTSWVYASRA
                     KNFLKTMLSLAQQREELSIIDDQIGAPTSAELIADITAHAIPQTIVDANKVGIYHLVA
                     SGETSWFGYANYAFTQARTLGQELAIQKVNPIPTSAYPTPATRPHNSRLDNQKIQRTF
                     GLTLPVWQEGVKRALTELLNK"
     gene            11612..12502
                     /gene="rmlA"
     CDS             11612..12502
                     /gene="rmlA"
                     /note="glucose-1-phosphate thymidylyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="RmlA"
                     /protein_id="QHE90308.1"
                     /translation="MSLKRKGIILAGGSGTRLHPITKGVSKQLLPIYDKPMIYYPLSV
                     LMLAGIREVLIISTPEDLPNFEKLLGDGSQFGIELSYKVQPSPDGLAQAFLIGEEFIG
                     QDNVCLILGDNIYHGQHFSEQLSAASAREHGATVFGYHVTDPERFGVVEFDKTGKVLS
                     IEEKPTQPKSPYAVTGLYFYDNRVVEFAKQVKPSARGELEITDINNAYLRDGSLNVEL
                     LGRGFAWLDTGTHESLLEAGHFIYTIEKRQSFKVACLEEIGFHQGWVSKEQLLESAEA
                     LKKTEYGQYLKKVWEESNED"
     gene            12492..13043
                     /gene="rmlC"
     CDS             12492..13043
                     /gene="rmlC"
                     /note="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /codon_start=1
                     /transl_table=11
                     /product="RmlC"
                     /protein_id="QHE90309.1"
                     /translation="MKIETTKIEGLLILHPTVFGDDRGWFMESFNQQRFAQSLEDLNL
                     PVPTFVQDNHSLSQKGVLRGLHYQKAPYAQGKLVRVVQGRVWDVAVDIRPDSKTYGEW
                     VGVELSAENKTMFWIPEGFAHGFISLEDNTQFLYKTTNYYNKESEGAIIWNDPTLAID
                     WPLAEVNEVLVSDKDQVASLFKK"
     gene            13063..13881
                     /gene="gtr111"
     CDS             13063..13881
                     /gene="gtr111"
                     /note="glycosyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="Gtr111"
                     /protein_id="QHE90310.1"
                     /translation="MDFIPNGISVVIPTYNRAHLIKESLQSVLDQTVQPLEIIVVDDF
                     STDNTEDVVKSLNSPLIKYFKNQRTKGANGARNTGIILSQGEFIAFHDSDDIWLSDKL
                     EKQLQVLQDQLDVDMCFCSLRQNDKKNTVIPRKKISSENIGHQLLKGNFISTQTIFIR
                     KVKIGSHLFDEELKRFQDWDFILGFKEINIFHLDIPLVVQDVSGVRISNKFKEIDSYK
                     AIFDKYPILADKSLYFRIISQKIILNKGFSLTSMIKLVFFLTLFYMNKVRNYFY"
     gene            13909..14979
                     /gene="wzy"
     CDS             13909..14979
                     /gene="wzy"
                     /note="oligosaccharide-unit polymerase"
                     /codon_start=1
                     /transl_table=11
                     /product="Wzy"
                     /protein_id="QHE90311.1"
                     /translation="MVYLTIIFVYIYNVFLSFFLSRLNKKYIYFLCLPLIIFLSWFGA
                     NNIKKISVDYENYSNWISDIFYTEKIDFFLDKDPGFALLVKGIQYLFGNEYFYIYFIF
                     IFLGVFSKLKLAVDWLPNTLIALFLVLCLSRYYIIHDVTQLRAGLVIVLGTLLSLNFI
                     NKNINIVWYSVFLVALSSIHSSIILLLLIMILDYSFKFLKKRYFTIIVFFSSLFSYFI
                     GGLITEKASVLFGGYFRYSVYLETGGFEDAKISIFSFFILIKIMIVLMNIIIWEKIND
                     FYRVLVSLSCIGLFFALAFSQIAVLGWRFSEIFAYFDILCIFTPLIFLKLDINARFLY
                     IIFWFVMSFLMLYSSLVVILNI"
     gene            14988..15887
                     /gene="gtr112"
     CDS             14988..15887
                     /gene="gtr112"
                     /note="glycosyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="Gtr112"
                     /protein_id="QHE90312.1"
                     /translation="MNSAIIVLFNPDLTHLNNFIGQLSGQTDKIILVDNTPNSLRKYG
                     HDEFVAEKLIYVDLKDNLGIATAHNAGIKKALEIGSEYVIIFDQDSSVPEGFIDSLVG
                     VDKKLRAEGKKIAAVGPSYIDIKTNTMAPVIQFNGLKVNRIMPKEDELYTPADYIISS
                     GTLIHAEAFKKVGLMMEELFIDYVDLEWGLRAKKMGYQCFVANHVIMKHSIGDRSIKV
                     PFSNKHVNIHSDFRKYFIIRNAFFLILYSNLQANWRIVQIPKTFMYFGFLCLFVSPRL
                     NNVKIFFQAFRDAVTKKMGKGSM"
     gene            15887..16705
                     /gene="gtr82"
     CDS             15887..16705
                     /gene="gtr82"
                     /note="glycosyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="Gtr82"
                     /protein_id="QHE90313.1"
                     /translation="MVDNMPKTIASIVLYKHSYAELKATLDSLFATPSIEKVILVDNH
                     SSNWAATLQHPKVVYEKSAGNFGFGYGHNIAIRKYASESDYFLICNPDICFKPEQFAR
                     LLDFVQSRSEGLFLPKIVYDNGEDQHGARLLPTPLNLFARRFSPSFAKKLDQQYLLKD
                     YSLDQPCFVPYLSGCFMLFDAEKLLAIKGFDERFFMYMEDVDLSRRCAEQFGAVYYPL
                     AQVVHVHEQASYKNKQLLKAHLKSAIQYFNKWGWIYDMGRSRLNAKCLDQISKF"
     gene            16746..17348
                     /gene="itrA3"
     CDS             16746..17348
                     /gene="itrA3"
                     /note="initiating transferase for oligosaccharide-unit
                     synthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="ItrA3"
                     /protein_id="QHE90314.1"
                     /translation="MLKRLVDIIIALSALILLMPVFLIVIYKVRKNLGSPVFFLQERP
                     GKDGKLFKMIKFRSMKDAVDQYGNILPDEERITPFGQKLRSTTLDEMPQLINVLKGDM
                     SIVGPRPQLPDFLQYYTPEQMRRHEVRPGMTGLAQVSGRNNLSWEEKFELDVQYVDTQ
                     SLWLDFKIMFKTAEVMLKKEGINAPDQAVGASRFTGSRDN"
     gene            17379..18254
                     /gene="galU"
     CDS             17379..18254
                     /gene="galU"
                     /note="UTP-glucose-1-phosphate uridylyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="GalU"
                     /protein_id="QHE90315.1"
                     /translation="MIKKAVLPVAGLGTRFLPASKSIPKEMVTVVDRPAIEYVVREAV
                     EAGIKQIIFVTHSAKVAIEDYFDHDFELETTLEQKQKFDLLKEITDILPKDVSIVSVR
                     QPKPLGLGHAVLCAKSIVGDNDFAVLLPDVLVKNKSGKNDLARMIERYETVHAAQIMV
                     EAIPDNLVNQYGIVDVPHSPAAGESIAMQGIVEKPAIGSAPSNLSVVGRYILPAKIMQ
                     LLEQTPKGAGNEIQLTDAIALLQQTDAVEAYCMRGQTFDCGSKLGYLKAVLHYGVEHP
                     QLGQAFKMMIAELEQ"
     gene            18272..19534
                     /gene="ugd"
     CDS             18272..19534
                     /gene="ugd"
                     /note="UDP-glucose 6-dehydrogenase"
                     /codon_start=1
                     /transl_table=11
                     /product="Ugd"
                     /protein_id="QHE90316.1"
                     /translation="MKIAVFGATLHAGVMAALLAEYGNQIYWCTSVTCEENFSILSYQ
                     DQEVNTYLNKQRKAGFLEECSFSGIPLDAEVYLFCYSPTQLQLALNTVEKLSQRPIIH
                     PRLMINGSTFGLQGTQKLKQYLPKDEWVYFPDVIQEGNAINSVLNVKHVIVGAETENA
                     CDIMRELLRPFFRFSYQYLFMPILDAEFTKLSISGMLATRVSYMNDLAMVAEKLGIDI
                     ANVKHGIAADTRIGAAYLSAGVGFGGENFSHDILTLSSTVSETGAKSRLLEQVWEINE
                     QQKEILFRKLWNYYHCDLSGKIVAIWGASFKENTSSIHNSPIHVLLAALWAQGVTVRL
                     HDPQALGEIAKIYGTRDDLILCDDQYDAVTGAQALCVVTAWKQYWGPDFKRLQQSMAH
                     PLILDGRNIYDPAYVKARGFAYEGVGRL"
     gene            19531..21210
                     /gene="gpi"
     CDS             19531..21210
                     /gene="gpi"
                     /note="glucose-6-phosphate isomerase"
                     /codon_start=1
                     /transl_table=11
                     /product="Gpi"
                     /protein_id="QHE90317.1"
                     /translation="MSKNIEQFPKEKLQGSTFASQLRSLGQQYENLHLNELFAAEPER
                     FQKYSVHFDQLFFDYSKHRVNQSVLDQLVTLANAKQLKQWIVRLFSQEKVNCTEQRAA
                     IHWALRLPAGHTQFPELTEQVHTQLQRMYALVEKIHAGQYRGATGEVIQDVVNIGVGG
                     SDLGPLMVTHALSDFKVQTVKPLNVHFVSTMDGSQLSEKLHKLRPETTLFIISSKSFG
                     TIDTLSNAQTVRQWLEKALGKHDRVVKSHFIGVSTKADKMTDWGIAPENQLLLWDWVG
                     GRYSLWSCIGFPIALTIGVKGFQQLLAGAHAIDEHFQHTSFEQNIPVLMALLGIWNNN
                     FLNIQTHAVLPYDGRLKYFAAYLQQLEMESNGKSVQRDGQKVELNTCPIVWGEVGPNA
                     QHAFYQLLHQGTQAVSCDFIAPIQRYNADHFTYVENAKALIEQHHLALSNCLAQSRLL
                     AFGNEALDSTELKNLPIYKQYEGNQPSSTLLLKELNPYSLGMLIALYEHKVFVQSVIW
                     NINPFDQWGVEKGKQIADQLLPILNGAQNDLSSLDASTRGLIKILLGKVDG"
     gene            21651..23492
                     /gene="pgt1"
     CDS             21651..23492
                     /gene="pgt1"
                     /note="predicted phosphoglycerol transferase"
                     /codon_start=1
                     /transl_table=11
                     /product="Pgt1"
                     /protein_id="QHE90318.1"
                     /translation="MIFLRQQLLFILIAFLSISISVYIAWDMNITWYQFYTYLISEKA
                     IFSILFNYAVIQLFFIILGRKYTALCLSQLFVIFLNFINKKKQQYLFTNLSPEDIFLL
                     PEAMTATPWHLQLIFFTLIIFSLIILLIAVRQESKATFHTYVPNIIIFGLISSGLIYL
                     NFIRSPTGACFSENKPMICASLQEFPNTRNDWIGDYRKIQDYGFVTFYVSKVLDNVTS
                     VLLPSRKISEQDIQQILQRHYLVQPLEKNEREYPNIVIVMEESFWDSHHLESGLPKDL
                     LSFVHQNQVSNLLSPSFGGGTANVEFEVLTSLNTTFFPNELLYVSKLKKPIYALPYYL
                     NSIGYQTFAMHNNYSYYYNRNKVYPDLGFEKFISLENMIAKKDLGKVVNLGGWTTDDL
                     IFDSIKSILKENELQPKFIYAITVENHPMYNDDRFGKQNYKFNKELSETEKQKLSTYT
                     AGTVRANQKLKELAEYLKTVDRPTILVVFGDHLPNLQEVYDSYGFFKDDPERTNLKNY
                     QTPFVVWSNYKLDKKPLKQPYIAASFVAPKLLKLAGLPLSDYYQFVDDVSSCYSVIHQ
                     KFINENLTCNFDKKALLKGYENLNKDVLDGYNHTYKIMQNNQKEMEQ"
     gene            complement(23520..24890)
                     /gene="pgm"
     CDS             complement(23520..24890)
                     /gene="pgm"
                     /note="phosphoglucomutase/phosphomannomutase"
                     /codon_start=1
                     /transl_table=11
                     /product="Pgm"
                     /protein_id="QHE90319.1"
                     /translation="MTTLTCFKAYDIRGKLGTELNEEIAYKIGRAYGQIYKPTTVVVG
                     CDIRLSSGALKQATIRGLNDAGVNVLDLGMTGTEEVYFAAFHLDVQGGIEVTASHNPM
                     DYNGMKLVRENARPISADTGLKEIQSLAETNNFEEVSQKGTTQSYNILPEFVDHLLTY
                     IEPAKIRPLKLVVNAGNGAAGHVIDAIEEKFKALNVPVEFIKIHHEADGTFPNGIPNP
                     ILIENRDSTRNAVLEHKADMGIAWDGDFDRCFLFDEKGQFIEGYYIVGLLAQAFLIKQ
                     SGEKIVHDPRLVWNTFDIVDEYKGVAVQSKSGHAFIKDVMREHNAVYGGEMSAHHYFR
                     DFAYCDSGMIPWLLTIALLSETGQSLSTLVENMIAKFPCSGEINFKVADTQTTIQKIF
                     DFYADQNPQIDRTDGVSLDFGAWRFNVRASNTEPLLRLNIESRADRQAQPMQHYVDEL
                     TGLIQS"
ORIGIN      
        1 ttagtcttct ttttgtgcct tataggcata agcatagtta tagccataac catagccagc
       61 gctagcacgt tgaatatcat tgagaataaa gccgttgact ttaacacccg cctgttcaaa
      121 acgattaaca gttagttcaa gctctttcat ttgtgacttc gcgtagcgtg caacaattaa
      181 gttcacacca gtatattgcg aaataataat accatcggtt accgcaagca ctggtggagt
      241 atcaataatg atgtggtcgt actggctttg tagctgctca agtaattcct taaactggtt
      301 tgagcttaaa atctctgaag gatttgttgg actcttacca cgagtaatca catctagatt
      361 cgttacctga gttttatgta atacttgtga caaatctgcc tgcccactta acaattctga
      421 tagacccggt tttacatcaa catcgaaata tttatgcata taaccacggc gcatatcggc
      481 atcgatcaat agtactcgtt tatcgccttg tgcaaaaata gttgctaggt tagttgaaat
      541 aaatgattta ccaacttcag gagatgggcc tgcaatcata atgatattat tttttgcatt
      601 tgctaatgca aagtgaatag ctgtacggat actacgtaag ctttcaatcg ctatatcatc
      661 actattttta accgcaagaa taggaatact cttcttcttc tttaaaatct tgatgcggct
      721 ttcttgaatt ggagaacgag ggacagttgc ataaactggt aaatccaatt cattttcaat
      781 ttgtccagaa tctttaatac ctgtacgtaa catattacgt aatagggcaa tcagcgtacc
      841 aataaaacca cccacaaata cagataaaat aagaactaat agtttctttg gtttaattgg
      901 tttaactggc tcgatggctg tgtcgacaat gcgtacattg ccaatttcac cggctttggc
      961 aatacgaagt tgttggtatg aatttaaaag agctgtatag agctgtgttt taacttcaac
     1021 ttcacgataa agctgtaaat actgacgttg aacatccggt aattgtttta aagtactatt
     1081 gagctcacca atttgcttat tgatcgcagc gagctggcca tttatttcgc gcattgccgg
     1141 atgttcggcc gtatattttg ctgccatttc agcttgtttt tgctcaagct ctgctttttt
     1201 agtttctaaa gtaatacttt gagttaaata caactcagat tccttagtca catcaactgt
     1261 attatattgt tgacggaatt tattaaattg acgctctgca tcatccaatt gctttttaag
     1321 atcaggcaac tgttcatcta aaaactttaa tgtttgagcg gattctgccg agcggcgctc
     1381 aatattttga gcactataag tcgctaaaat agcatttaaa actttagtga tatgttcttt
     1441 atcttgccct tgatagttaa gacctaaaac tcctgtaagc ttaccgcgtt ctgctacagc
     1501 atagtttgca ctaagtgcat ttacggcagc tggtaaagat aaattggtaa tattataggt
     1561 cgcgtcaaat tgatctttag taaagatggc aattttccat aaaccatgag gacctgcaac
     1621 gtgattagct tggtttaatg gaacagttaa gataacttct tcagtatctg ggtctgttaa
     1681 acgtaaagac tgtttatcaa aattaagaag taagtttttg tctagatagt aagctggaac
     1741 ttcaaattca cgtacttcaa aactttttaa gttatcttta aataaaactg attttttagt
     1801 gtattcagtt ttatattcgg tatcacttaa taaacgatgg gtaagtgtat tttcagtact
     1861 agacacctgt atatttaggt gtaaatcttt aatgacagat cctaggacta aacgagattt
     1921 taaaatttct atttctgctt gagcgggtga tttttgctcg atcatttgtg atagatcacc
     1981 taaaagcgca gcagaagcac ctttactgtc ttcaacctga accaaagcat caactgaata
     2041 ggtatctggt gttacacgta aatagagtag ggcacataca acgcttaaaa taacgcatag
     2101 agcaatgagt ttccactgag caatcaatga aaaaaacaat tcttttaagt caattgtatc
     2161 ttcggcatta gtattttgtt ggttcatatg cttaaaaatc tatacgttaa atataaggtt
     2221 tccagtcagt cacacattgt tgaatgagtt ggcaagtttc atcaaataca gcttggtcat
     2281 ggcggtaagg gtcgggcaca ttcttatttt gccaatgtcc taagcgatag gttttacctt
     2341 tcgcaaaggg ccaagtttgt tcaatatgct ttagctggtt attactcatc actaaaataa
     2401 gatcagcttt cttaataagc tcggcattga gttttctcgc aatatgaggc tgcatatcaa
     2461 tgcctaaacg ttgcatacaa agctgggcct tttcatcagc ctgatgtcca ataagtccag
     2521 aaatacccgc agattcaata ttgagttggg gatattgttg ttttaataaa tattctgcca
     2581 ttgggctacg gcagatattt ccaatacaaa ccaccaaaat gtttttaatt tgcataatat
     2641 tattgtccca aacggtctat gttatataaa gcatttgaga atggaataat ttggttaata
     2701 acacgttgcc agcgtgttaa gccagtcgca tcgacataaa caatatcatt actacgtaac
     2761 ctaaattgat tcgctaaacc aaaatctcca atactcatta aatttaaatg ataaatttcg
     2821 gttgtgcggt catttgggtt agtccgtact acataaatct tgctagcact acccgaagtt
     2881 ggattaatac ctaaactttc ccctaaagca tcgcttaaag tcataccttg atcacgcatt
     2941 ggtaatgctt gactttttcc agcttcgccc atcacataaa ttttttgatt ctcacgtgtg
     3001 ctcacataaa tagtgtcgtt tggttgaatc aatagcttat gtagtgaata gccagctttt
     3061 tctaaatcaa tagtatttaa gttataagtt cgaccatttc gaataagttg aatataagtg
     3121 ttatcccctg tagttgttac accgcctgcc atacctaatg cagtataaat actaataggt
     3181 tggtcactta gataaaattg accacctttg gtaacgctac cttgaacaga gaagcgctgc
     3241 ccctcataag acactacacg cactacaaca tccggatttt ttaaaaagcg ggctaattgg
     3301 cttcgtaact cacggttgac ttgagcaagc gttttaccgg cagctttgta gcgcccgacc
     3361 aacggaaact gaatataacc actttggtca atcgggtaac cattcgcttg aatagattgt
     3421 tcattactaa tattgtttac aggaggcgta atttccggat acgcccagag ctgaatagaa
     3481 aggacatcgc caggacttaa acggtaaata gattgttggt ttttaaataa tgatgcgtag
     3541 tcgcgttgat aatcgatttg agctggttgt attgctggta atgtctcttg agaaatttta
     3601 actacattta cggtggttcc gagatctgtt ttataaactc cctcactcgg aatatcataa
     3661 gtttgtaaac cggaagtaac cgcacagctg gcagcactta aacttaaggc aagaacagaa
     3721 aaaaactggc aatacttcac acgcgaccct ttgtgtattt atctttaatt gatattgtcc
     3781 actgcatagc gacaagtgtc tattaaacgc aggctgaact gattctagct gaaaagaaat
     3841 gaaaaaacat agaaaaatcg caaggctttg tatgtttagt ttatctaggc taggctttta
     3901 agcggtggtc acagtgtaga aatattaaaa atgtataatt ttggctaaat tagaaaagat
     3961 tgcttataaa tgttgtaaac acatttatac aattgacgta cggtgctaaa tgaaaatctg
     4021 atatagtacg ctgcactgtt agtgccaaaa gcatgattta ttagatataa actctaagga
     4081 aaaaggctcg tttatatgca aattgccaaa ttaaaaatag caattattgg gttaggctat
     4141 gttggcttgc cgttggcagt tgagtttgga aaaaaagtac cggttgtcgg cttcgatatt
     4201 tatcaaaaac gtatagatga gcttaagaat ggtcaagatc atactttaga agtttcacct
     4261 gaagaattaa agcaagcggt tcacctcaac tatactgccc atttagatga tttacaggac
     4321 tctaattttt ttatagtcac cgtacctacc ccaattgatg attttaaaca acctgatttg
     4381 actcctttaa ttaaagcatc cactagtatt ggtcaagtgc ttaaaaaggg agacgtggtg
     4441 gtatatgaat ccaccgtata tccaggtgcg acagaagagg tatgtattcc tgttttggag
     4501 aaagtatctg gactcaagtt taatcaagat ttctttgcag gctatagtcc agagcggatt
     4561 aaccccggtg ataagcagca ccgtgtaact aatattttaa aaatcacatc gggttctaca
     4621 cctgaggtag ctgattatat tgatgaaatt tataatttaa ttattgaggc aggcactcat
     4681 aaggcgccga atataaaagt agcagaagcg gctaaagtaa ttgaaaatac acagcgtgat
     4741 gtcaatatcg ctctgattaa tgaattggca cttattttta ataaattagg tattgatacc
     4801 gaagatgtac tcaaggctgc gggcacaaaa tggaactttt taccattccg acctggattg
     4861 gttgggggac attgtatagg tgtagatcct tattatctta ctcataaagc tcagtctatt
     4921 gggttgcatc ccgaaattat tttagcggct cggcgcctaa atgatcgtat gggtgagcat
     4981 gtggcgactc agcttataaa agagatggtc aagcaacgta ttcaggtggt tggtgctcgt
     5041 attttagtaa tgggtcttag ttttaaagaa aactgtcctg atattcgtaa tacaaaaatt
     5101 gtcgacttta tcaacgcctt gaaagagtat gacttagatt tagatatcta tgacccgtgg
     5161 gtgaatgata cagaagtaca acacgaatat gggttagcgc caattaaaga attacagcaa
     5221 ggcttgtatg atgcgatcgt cattgcagta gcacataacc aatttaaatc tatgagtgtt
     5281 gaagagtttc atacgttggg taaagaaaag tatgtgctat acgatttaaa atatgtttta
     5341 gataaagcag attcaaatct tagattgtaa ttatgatttt ataggtcatc ttatttagta
     5401 tgaataataa taaaattgcg ttagtagtga tagtgtatgg taaagcatta gaagatgcta
     5461 tgactataca aagcttgcta agctttgagg aaaaattgga gcatttactt atcgtaaata
     5521 atggcccagc agtaatagat gaaaatagtg cagtgctgac ttcattggca caaaaacacc
     5581 accacgttgt gttagaaaat caggtacaaa ataagccttt gagttggatt tataatgact
     5641 ttatccagca atatgatgct gattattatg ttttatttga tgatgatact gaaataaatc
     5701 ctgagtacca aagaaaaata tttattatgc aaggggtaga tatagagtta cctaaaatca
     5761 tttctatgaa tgataaagca caatattatc ccttagttga tggggtgata gagcaaaagg
     5821 atggaataat ctctaatgca aaagaaatat tctcaattgg ctcaggtttg gtgatttcta
     5881 aagacataaa acaatatttt atagaaaaca aaattgagtt gttcgattca cactttgctc
     5941 tctatggggt agattttagt ttcttcagaa agattaatca tatagcaaaa caaaaaaata
     6001 taattttttc aatttcttcc aatacatata ttaaacactc tttatcacgt actgaaaaag
     6061 aaacaaatgc atggcgtgat aaagaaagat tatatgactt agtcttgaca ctaaaatact
     6121 attattctta cgctgaatta cgaattttaa agttattttt caagaaaata ttgggtggaa
     6181 aaataaaaga tgcattgctc attttaagca ctgcatttaa tggtgcccat ccaagatgta
     6241 tgaataaagt attgaatgat tgaggtctcc aaagtgttag aagataggat tgatattgca
     6301 ttagctacat acaatggaga aaaatatatt acagaattat tggactctct tgatcaacag
     6361 acttatcaaa attttattgt acatgtttgt gatgatggtt ccaaagatcg gacaatagct
     6421 atttgtgaag cgcattcttt atttaaaaag ggcaaactag agatccatga aaaaactgga
     6481 ggaaatggtg cttcaaggaa ttttattcga acactttcct actgtaaaaa tccatatatt
     6541 gctttgtgtg atcaggatga tttttggatc cctaccaaac ttgagaaaat gttggttaag
     6601 acccaacatg aagaaggatc agaaaaaaag ccaacattaa ttttttcaga tctacaaata
     6661 gtggatgaaa aattacatat actttcacct tcttactttg cggtttcttc taaaagtaat
     6721 caatgttcca ctccatttga ttttttgttg agcaaccatg tgcctggttg taccatgatg
     6781 tttaaccaat cactaaagca agtatttgaa cctattcctc aagaattcag gatgcatgat
     6841 tggtggatta ttctcatagc agctttttgg ggaagagtca tttatttaga tgaaagctta
     6901 attcaatacc gccaacatgg gaataatact gtaggtgcgg taggaatgga taaacctact
     6961 ttaatacaaa agcttcgtac agtattgtta tataaaacga tactattaaa agtagatatg
     7021 gtgagaaaaa gtttcttacc ttatatccag caaaaagaga ttcaacaaga aaaactttct
     7081 ttggagcaaa aaaaatttat agatttattg caaagacgac ttccgctttc aaagagactc
     7141 cagattttta gtaaaacagt aacaggcgaa gatcgtttac tcagtttttt agtttggtgt
     7201 ttattatgag taaggcaata aataaagaag ttttttattt atatattatt caaatcgcca
     7261 atatggttat tccactattg tcattttcct atatggccaa tattttagga ttggtaggat
     7321 ttgggcaagt tagcttctat caaacagtaa gtttcctagc agcatttttt attgactttg
     7381 gtttcaatat gtctgcagcg cagaagatga gtatcagtct cgatgataaa tcaaaaatgg
     7441 atgagcttta tagcaatgtg caaagtataa agttttttat ttttttagtt gtatccgtat
     7501 taggtggcct tagtatatta tttttacctt tatcccatat agatgcgact ttattattta
     7561 ttggtattct ttcagctttc agtacaattt tgctgtctgg ctgggttttt caagggttag
     7621 ggcgtaactc agttttagct ttcttttctg tggttggtcg ggtagtttca gttggattaa
     7681 tttttttact aattcatcaa aaaagtgatg tgttactcgc agttataatt caagttgcaa
     7741 ttagtttttc aattggtttg gcagccatta tctattttta tcgaaaaaac gtggtaactt
     7801 ttcggattaa aactatatct atctttaaga tgagacagtt gtcagaagac agctaccata
     7861 actttaccgc atcacttttt actttagggt ttacatattt aaatccacta gtagttaaat
     7921 tttgttttgg cgatgctttt ttaggtttgt atgcgttagc tgataagtta gcggtaatac
     7981 ttaagcagtt ttttactcca gttacacaag cctattacag tcgcatgtgt attttgagcc
     8041 atgaaaaaaa atatcaagag ttaatacaaa atgcaaaaaa agtcgctatt ttttttgcaa
     8101 ctattagcac attggctttt tttggtaacc tattgattgg taattatatt tataattttt
     8161 tatttggtcc ggaatataag attgtaagtt tattaagtat tatgattatg acgcaattta
     8221 ttgtgtcaat ggctatggta cttgtcaatt taattattat tccaacagaa aatagtagaa
     8281 ttttgaagaa atactatctt ataggtttaa tttttcactt cggctatttt tatttctttg
     8341 ttaaatattt acatatttat ggagttgcta gtgctatctt gctaaccgaa acaattctta
     8401 cactgtcatt ctttatgtat gtaagaaaat acttttcaaa agttttaacg taaatctaaa
     8461 ggttatttta tgaaaataac agtagttggt acaggctacg tgggtttatc aaatgcgatg
     8521 ttgttttcta aacagcatga agtgactgcc ctcgatattg atgccacaaa aattgataaa
     8581 cttaatcaag gcatatctcc tattcatgac gaccttattc aagagtattt gactgataat
     8641 tcaaatttta aagcaacatt agataaacaa tctgcatata tggatgcgga agttattatc
     8701 attgccacac ccaccaatta cgatgaagca agcaattatt tcgacactag ctcgattgaa
     8761 tctgtgcttg aagatttaag tcatttgaaa agcaatgcta ttattgtggt gaaatctaca
     8821 attcctgtgg gttttactga gcgcatgaag gtaacgtatc cgacattgaa aattgttttt
     8881 tctccggaat tcctacgtga gggtaaagca ctatatgata acttgtatcc atcacggatt
     8941 gtggtgggta gtacctcaga agtgggtaaa ttagttggtc agctatttaa aaatgctagt
     9001 ttaagacctg atgtagatgt actacaaatg gatgcaacag aagctgaagc agtaaaactc
     9061 ttttctaaca cttatttggc aatgcgtgtc gcctatttta atgagttaga ttcatattgt
     9121 gcatcacgtg ggctaaactc aaaagatatt attcaggctg taggattaga tccacgtatt
     9181 ggagcacatt ataacaaccc gtcatttggg tatggtggtt attgtttacc aaaagacaca
     9241 aagcaactgc tagctaatta tcaagatgtc ccacaaaatt tgattggagc aattattcag
     9301 tcaaatacaa cacgaaaaga ttttattgcc gagcagattt tggcaagaaa gccaaaagtg
     9361 gttggtgtat atcgtttagt aatgaaacaa ggttcagata actttagaca atctgcaatt
     9421 caaggtgtaa tgaagcgtct aaaagccaaa ggtgtagaag tcattgtgtt tgagccgagt
     9481 ttaaatgagt caacattttt taactcacgt gtgttgaccg attttgatag ttttaaacaa
     9541 gagtcggatg taattattgc aaaccgtatg gtgagtgagc tcgaagacgt cattgacaaa
     9601 gtttatactc gtgatttatt tggtgaaaat taattatact taggtagttg tatgaaaatt
     9661 ttaattactg gtggcgctgg ttttattggt tcagcggtcg ttcgtcatat tatccagaat
     9721 acagaagatg aagtattaaa tgtcgataaa ctgacctatg caggaaattt agaatcttta
     9781 atttctgtgg aaaataatcc acgttatcag ttttctcaaa cagacatctg tgatcgtgct
     9841 gctttagata agttatttga aacattccag ccagatgcag ttatgcacct tgctgcagag
     9901 tctcatgtgg atcgctctat tactggtcct tatgctttta tcgagactaa cgtgattggt
     9961 acttaccaaa tgttggaggc gagccgtgct tactggttaa gtctaaatga tgaaaagaaa
    10021 gcagctttcc gttttcacca catttcaacc gatgaagttt atggtgattt agaaggaact
    10081 accgacttat ttactgaaac tacatcatac tcgccaagct caccatattc agcaagtaaa
    10141 gcaagttcag atcatttagt tcgagcatgg aatcgtacgt atggtttgcc agtgttagtg
    10201 actaactgtt caaataacta tggcccattc catttccctg aaaaacttat cccactcatg
    10261 attttaaatg ccctacaagg caaatcattg ccagtatatg gcaatggtca acaaattcgt
    10321 gactggttgt ttgtagaaga tcatgcacgt gcgctttata cagtggttac gcaaggtact
    10381 gtaggtgaaa catataatat tggtggacat aacgaaaaag ctaaccttga tgttgtacat
    10441 gcaatttgtg atctacttga agaacttgca ccacataaac cggaaggtgt agcacagtat
    10501 aaagatctga ttacatatgt gaaagatcgt ccaggccatg acgtgcgtta tgcaattgat
    10561 gcgaccaaaa ttaaagaaga actcaactgg gtaccgaaag agtcatttga aactggttta
    10621 cgtaaaacag ttgaatggta tttaaataac aaagagtggg ttgaacacgt gcaaagtggt
    10681 gaataccaat cttggttaaa caagcaatat caaggataac tatgaaaatc ttattgcttg
    10741 gaaaaaatgg acaagtgggg tgggagctgc aacgcgcgct tgcaccttta ggtgatgtca
    10801 ttgctttaga tcgtcatggt ttagatagct tgtctggtga tatgacccaa ccacaggcga
    10861 tttatgacac gattttggca gtacagccag atgttgttgt caatgcttct gcatatacag
    10921 ccgttgattt ggcagaaact gagcaagaac tagctgatat tatcaatcac caaactgtaa
    10981 aagcggcagc agaagcctgt cagaaaacaa atgctttatt ggtgcattat tcaacagact
    11041 atgtttttga aggtacagga acgaccgctt ttgttgaaac tgatgcaatt gcgccattaa
    11101 acgtttatgg aaaaaccaaa gcattgggtg agcaagcgat tgtagatagt ggctgccgtt
    11161 atttgatctt tagaacctca tgggtgtacg cttcaagagc aaaaaatttc ttgaaaacca
    11221 tgttaagtct agctcagcaa cgtgaagagt tatctattat tgatgaccag attggtgcac
    11281 caacttcagc ggagttgatt gcagacatca ctgcacatgc tattccccaa acaatagtgg
    11341 acgcaaacaa agtcggcatt tatcacttgg tggcaagtgg tgagacttct tggtttggtt
    11401 atgcaaacta cgcctttaca caagcacgta ctttggggca agagttggcg atacaaaagg
    11461 ttaatcctat tccaacaagt gcttacccaa cgcctgcaac acgaccacac aattcacgat
    11521 tagataatca gaaaatacaa cgcactttcg gcctcacttt accagtctgg caagaaggtg
    11581 ttaaacgagc attaacggag cttttaaaca aatgagctta aaacgtaaag gtattatttt
    11641 ggcaggtggg tctggtacac gcttacatcc tattactaaa ggtgtatcga agcagctttt
    11701 gccgatttat gataaaccaa tgatttacta tccgctgtca gtacttatgc tcgcgggtat
    11761 tcgagaagta ttgattattt caacaccgga agacttacca aactttgaaa aactcttggg
    11821 tgatggttca cagtttggta ttgagctcag ctataaagta caaccttctc cagatggttt
    11881 ggcccaagct ttcttaattg gtgaagagtt tattggtcaa gataatgtat gtttgatctt
    11941 gggagataat atttaccatg gtcagcactt tagtgaacag ttaagcgcag cttctgcacg
    12001 tgaacatgga gcaacggtat ttggctatca tgtgacagat cccgagcgtt ttggtgttgt
    12061 ggagtttgat aagactggta aagtgctaag tattgaagaa aagccaaccc aaccaaaatc
    12121 gccttatgca gtaacaggtt tatatttcta cgataaccgt gtcgttgagt ttgcaaaaca
    12181 agtgaaacca tctgcgcgtg gtgagttaga aattaccgac attaacaatg cttacttacg
    12241 agatggttca cttaatgttg aattacttgg ccgtggtttt gcatggttag atacaggcac
    12301 gcatgagtct ttgcttgaag ctggtcattt catctatacc attgaaaagc gtcagtcttt
    12361 taaagtggca tgtttggagg aaattggttt ccatcaaggt tgggttagca aagaacaact
    12421 tttagaaagt gcagaagcat tgaaaaaaac cgaatatggt caatatttga aaaaagtttg
    12481 ggaagaatca aatgaagatt gaaacgacta aaattgaagg gcttttaatt cttcatccaa
    12541 ctgtttttgg tgatgaccgt ggttggttta tggaaagttt taaccaacaa cgttttgctc
    12601 aatcacttga agatttaaat ttgccagttc caacttttgt acaagataac cattcattgt
    12661 cacaaaaagg tgtgttgcgt ggtttacatt atcaaaaagc accctatgcg caaggaaaac
    12721 tggtacgtgt tgtacaaggt cgtgtttggg atgtggctgt agatattcgt ccagactcaa
    12781 aaacctatgg cgagtgggtt ggggtggaac tcagtgctga gaacaaaact atgttttgga
    12841 ttcccgaagg atttgctcac ggttttatct ctttagaaga caatactcag tttttgtaca
    12901 aaactaccaa ttactacaat aaagaaagtg aaggggccat tatttggaat gacccaacac
    12961 ttgcgattga ttggccatta gcagaagtta atgaagtatt ggtgagtgat aaagatcaag
    13021 ttgcatcttt atttaaaaaa taagataaaa gagaaagagt ttatggattt tatacctaat
    13081 ggtattagtg ttgtgattcc aacctataac agagcacact tgattaaaga atcactacaa
    13141 agtgttttag atcaaacagt gcagccgctt gaaattatag ttgtggatga tttttcaact
    13201 gataatactg aagatgttgt aaagtcttta aactcacctc ttatcaaata ttttaagaat
    13261 caacgcacaa agggagctaa tggtgcccgt aatacaggga ttatattgtc gcaaggtgaa
    13321 tttattgctt ttcatgatag tgatgatata tggttgtctg ataagttaga gaaacaatta
    13381 caagtgttgc aagatcagtt agatgttgat atgtgtttct gctctttaag acaaaatgat
    13441 aagaagaata ctgttattcc tagaaaaaaa attagctcag aaaatattgg tcatcagctt
    13501 ctaaagggta acttcatcag cacgcaaacg atttttatta gaaaagtgaa aataggaagt
    13561 catttatttg atgaagaatt aaaaagattc caagattggg actttattct tggctttaaa
    13621 gaaattaata tttttcattt ggatattcct ttggttgtgc aggatgtatc tggtgtccga
    13681 attagtaata aatttaaaga aatagattct tataaggcta tttttgataa atatcctata
    13741 ctagccgata agagtttata ttttagaatt ataagccaaa agattatact gaataaagga
    13801 tttagtttga catcaatgat taaattagtg tttttcctta ctttatttta tatgaataaa
    13861 gtaagaaatt atttttattg agttagtgct tttgtttttt ggtggaatat tgtgtattta
    13921 acaataattt ttgtatatat ttataatgtt tttttgagtt ttttcttgtc gagattaaac
    13981 aagaagtata tttatttttt gtgtcttcct ttaattattt ttttatcttg gtttggtgca
    14041 aataatataa aaaaaattag cgtagattat gaaaattata gtaattggat tagtgatata
    14101 ttttatactg agaaaattga ttttttctta gataaagatc ctggttttgc attgcttgtt
    14161 aagggtattc aatatttatt cgggaatgaa tatttttata tttactttat ttttattttt
    14221 ttaggcgttt tttctaagtt aaaattagct gtagactggt tgccaaatac attaatagcg
    14281 ctttttctag ttctttgtct tagccgatac tatattattc atgatgtaac acaattaagg
    14341 gcaggtttgg taattgtact tgggacatta ttatcactta atttcataaa taagaatatt
    14401 aatatagttt ggtatagtgt atttctagtt gcgttatcca gtatccactc ttctataatt
    14461 ctattattac tcattatgat tttagattat tcatttaaat ttctaaaaaa aagatatttt
    14521 actataattg ttttttttag tagtttattt tcctatttta ttggtggttt aattactgaa
    14581 aaggctagtg ttttatttgg tggttatttt agatatagtg tgtatttaga gacgggtggg
    14641 tttgaagatg caaagattag tatattttct tttttcatat taataaagat tatgattgtt
    14701 ttaatgaata taattatatg ggaaaaaata aatgattttt atagagtatt ggtttcatta
    14761 tcttgtattg ggttgttttt tgctttagca ttttctcaaa tagctgtgct gggttggaga
    14821 ttttcagaga tatttgcata ctttgatatt ttatgtattt ttacaccttt gatttttctt
    14881 aagttagata taaatgctag atttttatat attatttttt ggtttgttat gtctttttta
    14941 atgctgtata gcagcttagt agttattttg aatatatagg tattaatatg aattcggcaa
    15001 taatagtttt atttaatcct gatctaacac atcttaataa ctttatagga cagctaagtg
    15061 gtcaaactga taaaatcatt ttagttgata acacaccaaa ttctttaaga aagtatggtc
    15121 atgatgagtt tgttgcagaa aaactcatct acgttgattt aaaagataat ttgggcattg
    15181 ctacagcaca caatgcaggc ataaaaaaag cgttagaaat tggctctgaa tacgttatca
    15241 tttttgacca agactcatct gttcccgaag gctttataga ttcgttagtg ggtgtagata
    15301 aaaaattaag agcagaaggt aaaaaaatag cagcagttgg cccctcttat attgatatta
    15361 aaaccaatac catggcacct gtaattcagt ttaatggctt aaaagttaat agaattatgc
    15421 caaaagaaga tgaactttat accccagcag actacattat ttcatctggt acactcatcc
    15481 atgctgaagc ttttaaaaaa gttggattaa tgatggaaga gttgtttatt gattatgttg
    15541 atttggaatg ggggttacgt gccaagaaaa tgggttatca gtgctttgtg gcgaatcatg
    15601 ttattatgaa acattccatt ggtgatcgtt caataaaagt tcctttctca aataaacacg
    15661 ttaatattca ttctgatttt agaaagtatt ttattattag aaatgcattt tttttgattc
    15721 tatattcaaa tttacaagca aattggcgta ttgtgcaaat accgaaaaca tttatgtact
    15781 ttggtttctt atgtttattt gtgtcaccga gattgaataa tgtgaagata ttctttcagg
    15841 cattcagaga tgcagtaaca aaaaaaatgg gtaaaggaag tatgtaatgg tcgataacat
    15901 gcctaaaacc attgcttcga tcgttttata taaacatagc tatgctgagt taaaagcaac
    15961 actcgacagt ttatttgcta ctccaagcat tgaaaaagtt attttggtcg acaaccattc
    16021 aagtaattgg gctgcaacac ttcaacatcc taaagttgtt tatgagaaat cagcaggcaa
    16081 ctttggcttt ggttatggac acaatatcgc tattcgtaaa tatgcgtcag aaagcgatta
    16141 ttttcttatt tgtaatcccg atatttgctt caaacctgag caatttgctc gattattaga
    16201 ttttgttcaa agccgttcag aaggtttgtt tttaccaaaa attgtctatg ataatggtga
    16261 agaccaacat ggtgcacgct tattacccac ccctttaaat ttatttgctc gtcgtttttc
    16321 accttctttt gctaaaaagc ttgatcaaca atatttgtta aaagattact cacttgatca
    16381 gccatgtttc gtaccttacc tttcaggttg ctttatgtta tttgatgcag aaaaactttt
    16441 agcaattaag ggattcgatg agcgtttctt tatgtatatg gaagatgttg atttgtcacg
    16501 tcgttgtgca gagcaatttg gtgccgttta ctatccatta gcacaagtag tccatgttca
    16561 cgaacaagca tcatataaaa acaaacaatt acttaaagca cacttaaaaa gcgcgataca
    16621 atactttaat aaatggggat ggatttatga catggggcgt agtaggctta acgcaaaatg
    16681 tttagaccaa atctctaaat tctaaataat gaagctttta aaatgaaatt agtaggtata
    16741 tccagatgtt aaaaaggctt gtagatatta tcattgccct atctgcctta attcttctaa
    16801 tgcctgtttt tttgattgta atttataaag ttaggaaaaa cttaggttcc cctgtctttt
    16861 tcttacaaga acgtccgggc aaagacggta aattatttaa gatgattaaa tttcgttcta
    16921 tgaaggatgc ggttgatcaa tatggcaata ttttaccaga tgaagagcgg attacccctt
    16981 ttgggcaaaa gttacgttct actacactcg atgaaatgcc tcagctgatt aatgtactta
    17041 aaggcgatat gagtattgta ggaccacgcc cacagttacc agatttttta caatattaca
    17101 cgccagaaca aatgcgccgt catgaagttc gtcctggtat gactggactt gcccaagtga
    17161 gtggccgcaa taatttgagt tgggaagaaa aatttgagct agatgttcag tatgttgaca
    17221 cgcagagttt atggctcgat tttaaaatta tgtttaaaac agcagaagtc atgttgaaaa
    17281 aagaaggaat taacgcaccg gatcaagcag taggcgctag tcgtttcacc ggttcaagag
    17341 ataattaagt tttgtaaata atagttggta acagttcaat gattaaaaaa gcagttttac
    17401 cagttgcagg tttaggcacc cgttttttac cagcaagtaa atcgataccc aaagaaatgg
    17461 ttacagttgt tgatcgtcct gctatcgaat atgtagtacg tgaggcagtt gaagcaggta
    17521 tcaaacagat tatttttgtg actcactctg ctaaggttgc tattgaagat tattttgacc
    17581 atgactttga gctagaaact acattagaac aaaaacaaaa atttgactta cttaaggaaa
    17641 ttactgacat tttacctaaa gatgtgagta tcgtaagtgt acgccaaccg aaacctctag
    17701 gcttaggaca tgccgtactt tgtgctaaaa gtattgtcgg tgataatgac tttgctgtgc
    17761 ttttacccga tgtgctagtt aagaataaat cagggaaaaa tgatttagcc cgtatgatag
    17821 agcgttatga aacagtacat gctgctcaga ttatggttga agctatacca gataacttag
    17881 ttaatcaata tggtattgtt gatgtgcccc attcaccagc cgctggtgaa agtattgcca
    17941 tgcaaggcat tgttgaaaag cctgctatag gttctgcacc gtcaaattta tcagtagttg
    18001 ggcgttatat tttaccagca aaaattatgc aacttttaga acaaactcct aaaggtgctg
    18061 gtaatgaaat tcaacttacc gatgcaattg ccctattaca gcaaacagac gccgtagaag
    18121 cttactgtat gcgaggtcaa acttttgact gtggtagtaa gttagggtat ttaaaggcgg
    18181 tattacatta tggtgttgag cacccgcaat tagggcaagc atttaaaatg atgattgccg
    18241 agttagaaca ataagatatt gtaggtgtaa aatgaaaatt gcagtttttg gtgcaacttt
    18301 acatgctggt gtaatggcag cattattggc tgagtatggt aatcaaatct attggtgtac
    18361 aagtgtaacc tgtgaagaaa atttttctat actttcttat caagatcagg aagttaatac
    18421 ttatttgaat aagcagagaa aagcaggttt tttagaagaa tgttcttttt cagggatccc
    18481 tttagatgct gaagtttatt tattttgtta tagtccaacg caattgcaac ttgcattaaa
    18541 tacagtagaa aaacttagcc aacggccaat tattcaccct cgtttaatga ttaatggttc
    18601 aacttttggt ttacagggaa cccaaaaact taaacagtat ttaccaaaag atgaatgggt
    18661 ttattttcct gatgttattc aagaaggaaa tgctattaat agtgtcctca atgtgaaaca
    18721 tgtgattgtt ggagcggaaa cagaaaatgc atgtgatatc atgcgtgagt tactacgacc
    18781 atttttccgt ttcagttatc agtatttatt tatgccaata ttagatgctg aatttaccaa
    18841 attaagtatt tcaggcatgt tggcaacacg tgtcagctac atgaatgatt tagcaatggt
    18901 agctgaaaaa ctcgggattg atattgctaa tgtaaaacat ggtattgctg ctgatacacg
    18961 tattggcgca gcttatctat cggctggtgt gggcttcggc ggtgaaaatt tttcacatga
    19021 tattttaaca ctttcgagta ctgtgtctga aacaggagct aaaagtcggt tattagaaca
    19081 ggtttgggaa attaacgaac aacaaaaaga aattttattc cgtaagttat ggaattatta
    19141 tcattgtgac ttgagcggca aaattgttgc aatttggggt gcttcattta aggaaaatac
    19201 ctccagtatt cataattccc ctattcatgt tttgttagct gctttatggg ctcagggagt
    19261 aacagtgcgt ttacacgacc cacaagcttt aggtgaaatt gcaaaaatat atggtacacg
    19321 tgatgattta atattatgtg atgaccaata tgatgcagtt acaggtgctc aagcgctttg
    19381 cgtagtaacc gcatggaagc agtattgggg gccggatttt aaacgtttac aacaaagtat
    19441 ggctcatcct ctaattttgg atggacgtaa tatttatgac cctgcatatg ttaaagctcg
    19501 aggttttgca tatgaaggag taggtcgttt atgagtaaaa atatagaaca attcccgaaa
    19561 gagaagctgc agggctcaac atttgcctca cagttaagat cattagggca acaatatgaa
    19621 aatcttcatt taaatgagct atttgctgca gaaccagagc gctttcaaaa gtattctgtt
    19681 cattttgatc aacttttttt tgattatagt aagcaccgtg taaatcaatc tgttttagat
    19741 cagttggtga ctttggcaaa tgccaaacaa ttaaaacagt ggattgtacg tttattttca
    19801 caagaaaaag taaactgtac ggaacagcgt gcagcaatac attgggcatt acgtttacca
    19861 gcaggacata cccaatttcc tgagctcact gaacaggtac atacacaatt acaacgtatg
    19921 tatgcattgg ttgaaaaaat tcatgctggt caatatcgtg gtgctacggg tgaagtgatt
    19981 caagatgtag tgaatattgg agtaggggga tctgatttgg gtccactcat ggtcactcac
    20041 gcattgtctg actttaaagt acagacagta aagcctttaa atgtacactt tgtttctaca
    20101 atggacggca gtcagctttc tgaaaaacta cataagctgc gcccggaaac aactttattt
    20161 attatttcct caaagtcatt tggtaccatt gatactttat caaatgcaca aacagttcgt
    20221 cagtggcttg aaaaagcttt aggaaagcat gaccgggttg taaaaagtca ctttattggt
    20281 gtgtctacaa aagctgataa gatgacagac tggggaattg cccctgaaaa ccagttgcta
    20341 ctttgggatt gggtgggtgg tcgctattct ctctggtctt gtattggttt ccctatcgct
    20401 ttgacaatcg gcgttaaagg tttccaacag cttttagctg gagcccatgc tattgatgaa
    20461 cattttcaac atacaagttt tgagcaaaat ataccggttc tcatggcatt attgggaatc
    20521 tggaataata attttttaaa tattcagacc catgcagtat taccctatga tgggagatta
    20581 aagtattttg ctgcttattt acagcagctt gaaatggagt ctaatggtaa gtcggtacaa
    20641 cgtgatggtc aaaaagttga attaaatact tgtcccattg tatgggggga ggttggtcca
    20701 aatgcgcaac atgcctttta ccaactctta catcaaggga ctcaggcagt aagttgtgat
    20761 ttcattgcac cgatacaacg ttataatgcg gatcatttta cctatgtaga aaatgctaaa
    20821 gcattaattg agcaacatca tttagcgtta tcaaattgtt tggcacaatc acgtttattg
    20881 gcttttggca atgaggcttt ggattcaact gaattaaaga atctgccaat ttataaacaa
    20941 tatgaaggta accagccaag ctccacatta ttattaaaag aacttaatcc atatagcttg
    21001 ggtatgctga ttgctttata tgaacataaa gtatttgttc agtctgtgat ttggaacatt
    21061 aacccatttg atcaatgggg tgttgaaaaa ggtaagcaga ttgctgatca gttacttcca
    21121 attttaaatg gtgctcaaaa tgatctttca tcacttgatg cttcgacgcg tggtttgatt
    21181 aaaattttat taggaaaagt tgatggttaa tattctaatc actggcgttg cgggtatact
    21241 tcgcttctac tgaagctact catagctatg ctatccaata actatgagta tacaaagctg
    21301 attgtcgagc aaatattgta aaaaaattaa tggctaactc taaatagtca tttgttttac
    21361 tcgactattt caatactata ggagtatata agtgaacaag atatactccg attttgagta
    21421 tgcttcagcg gggggcagct cttttgctaa aaaatgctct tgcagttctg agttgttgtg
    21481 atagaaacct ttatagggct taaaagatct gcttaaggat agttggagat gtaagaattg
    21541 ttcaactcga tataaaaatt gattatttaa tttttctgaa agcggctaca gttatagtga
    21601 atgcttccat gctagtattt gccacaatct gttagcctct ttttgtagtc atgatttttc
    21661 tacgtcaaca actgctattt atccttattg ccttcttatc catcagcata agtgtatata
    21721 tagcatggga tatgaatata acttggtatc agttttatac ttatttgatt tcagaaaagg
    21781 ctattttttc aattcttttt aactatgcag tcattcagct attttttatt atacttggac
    21841 gtaaatatac tgcactgtgt ttaagccaat tattcgttat atttttaaat tttattaata
    21901 aaaagaagca acaatattta tttactaatt taagtcctga agatattttc ttacttccag
    21961 aagcaatgac ggccacccct tggcatttac agcttatctt ttttaccctc attatttttt
    22021 cacttatcat actcctcatt gctgtacgcc aagaaagtaa agcgactttt catacttatg
    22081 tccctaatat tattatcttt ggattaatca gtagtggttt aatttactta aattttatta
    22141 ggagccctac aggcgcttgt ttttccgaaa ataaacctat gatttgtgcc agcttacagg
    22201 aattcccgaa taccagaaat gactggatcg gtgattaccg aaaaattcaa gattatgggt
    22261 ttgtgacttt ttacgtttct aaagtattgg ataatgtaac cagcgtattg ttacctagtc
    22321 gtaaaatatc tgagcaagac atacagcaaa ttttgcagcg acattacttg gttcaacctt
    22381 tagaaaaaaa tgagagagaa tatccgaata ttgttattgt tatggaggag tctttttggg
    22441 actctcatca tttagaaagt ggattaccta aagatttatt atcttttgtt caccaaaatc
    22501 aagtttctaa tttattgtcg ccttcatttg gtggaggtac agcgaatgtc gagtttgaag
    22561 tacttacgag cctcaataca acttttttcc caaatgaatt gttatatgtt tctaagctaa
    22621 agaagccaat ttatgctcta ccttattatt taaattcaat tggttaccaa acatttgcaa
    22681 tgcataataa ttatagttac tactataatc gtaataaggt atatccagat ttagggtttg
    22741 agaaatttat atcgcttgaa aatatgattg ctaaaaaaga tcttgggaaa gtggttaatt
    22801 tgggtggttg gacgacagat gatcttattt ttgattcaat taagtctatt ttaaaagaga
    22861 atgagctaca gccaaagttt atttatgcaa ttactgtcga aaatcatcca atgtataatg
    22921 atgaccgatt tggcaaacaa aattataaat ttaataaaga gttgtctgaa actgaaaaac
    22981 aaaaactaag tacttatact gctggaactg tgcgtgctaa ccaaaagtta aaagaactcg
    23041 ctgaatattt aaagacagta gatcgaccaa caattttagt agtttttggt gatcatttgc
    23101 ctaatttaca agaagtttat gatagctatg gtttttttaa agatgatcct gagcgaacta
    23161 acttaaaaaa ttaccagaca ccgtttgtag tgtggagcaa ttataaatta gataagaaac
    23221 ctttgaagca gccttatatt gctgcaagtt tcgttgctcc aaaactatta aagctagcag
    23281 ggttaccttt gtcagattac tatcaatttg ttgatgatgt ctcgagttgt tatagtgtca
    23341 ttcaccaaaa atttatcaat gaaaatctaa cgtgtaattt tgataagaaa gcgctgttaa
    23401 aaggttatga aaatctaaat aaggatgtat tagatggata taatcatact tataaaatta
    23461 tgcagaataa ccaaaaagag atggaacaat aatgttccat ctctttgaga tgaaccctat
    23521 taagactgaa ttaatccagt caattcatct acataatgtt gcattggctg agcctggcgg
    23581 tctgcacggc tttcaatatt aagacgtagt aaaggctcgg tgtttgacgc acggacatta
    23641 aaacgccacg caccaaagtc gaggcttacc ccatcggtac ggtcaatttg tggattttga
    23701 tcggcataga agtcgaaaat cttttgaatc gtagtttgtg tatcggctac tttaaagttg
    23761 atttcaccac tacaagggaa cttggcaatc atattttcaa cgagtgttga gagagattgt
    23821 cctgtttcag agagtagagc aatggtgagt aaccagggaa tcataccact gtcacagtaa
    23881 gcgaaatcac ggaaatagtg gtgagcactc atttcaccgc cgtatacggc attgtgttca
    23941 cgcataacat ctttaataaa tgcatgcccc gattttgact gtacagcaac acctttatat
    24001 tcgtcgacga tatcaaatgt gttccacact aaacgtgggt catgcacaat tttttcgcct
    24061 gactgtttga ttaagaaagc ttgagccaat aggccaacaa tatagtagcc ctcaatgaat
    24121 tgtccttttt catcgaacaa gaaacagcgg tcaaagtcgc cgtcccatgc aatacccata
    24181 tctgctttat gctcaagaac agcatttcgg gtactgtcac ggttttcaat taaaattggg
    24241 ttagggatgc catttgggaa agtaccatct gcttcatgat gaattttaat aaattcaacc
    24301 ggtacattaa gtgctttaaa tttttcctca atggcatcaa ttacatgacc agctgcacca
    24361 ttgcccgcgt ttaccactaa ctttaaggga cggatttttg caggttcaat ataagtcagt
    24421 agatggtcaa cgaactcagg caaaatatta tagctttgag ttgtgccttt ttggctaact
    24481 tcttcaaagt tattggtttc tgctaaggac tgaatttctt ttaaaccggt atcggcacta
    24541 attggacgag cattttctcg aaccaatttc ataccgttat agtccattgg gttatgactc
    24601 gcagttactt ctataccacc ttgtacgtct aaatgaaaag ctgcaaagta aacttcttca
    24661 gtacccgtca tgcctagatc aagcacattc acacccgcat catttaatcc acggatggtc
    24721 gcttgtttta aagccccact gcttaggcga atatcacaac ctacaaccac agtcgttggt
    24781 ttatagattt gtccgtaagc gcggccaatt ttataggcga tttcttcatt caattcggtg
    24841 ccgagtttac ctcggatatc ataagcttta aaacacgtta aagtagtcat
//

