LOCUS       NZ_CVRR01000009         7242 bp    DNA     linear   CON 30-AUG-2021
DEFINITION  Roseburia faecis strain M72, whole genome shotgun sequence.
ACCESSION   NZ_CVRR01000009 REGION: 42847..50088
VERSION     NZ_CVRR01000009.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMEA1710514
            Assembly: GCF_001406815.1
KEYWORDS    WGS; RefSeq.
SOURCE      Roseburia faecis
  ORGANISM  Roseburia faecis
            Bacteria; Firmicutes; Clostridia; Eubacteriales; Lachnospiraceae;
            Roseburia.
REFERENCE   1
  AUTHORS   Informatics,Pathogen.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2015) SC, Wellcome Trust Sanger Institute, CB10
            1SA, United Kingdom
COMMENT     REFSEQ INFORMATION: The reference sequence is identical to
            CVRR01000009.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 08/30/2021 18:45:22
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 5.2
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Genes (total)                     :: 3,308
            CDSs (total)                      :: 3,251
            Genes (coding)                    :: 3,112
            CDSs (with protein)               :: 3,112
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 29 of 139
            Pseudo Genes (incomplete)         :: 105 of 139
            Pseudo Genes (internal stop)      :: 20 of 139
            Pseudo Genes (multiple problems)  :: 13 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7242
                     /organism="Roseburia faecis"
                     /mol_type="genomic DNA"
                     /strain="M72"
                     /db_xref="taxon:301302"
                     /collection_date="1800/2014"
     gene            complement(1..945)
                     /locus_tag="M72_RS04730"
                     /old_locus_tag="M72_24111"
     CDS             complement(1..945)
                     /locus_tag="M72_RS04730"
                     /old_locus_tag="M72_24111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009860844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate kinase"
                     /protein_id="WP_055067378.1"
                     /translation="MDVVALGELLIDFTENGVSGQGNPLFEANPGGAPCNVLAMLSRL
                     GHKTAFIGKVGNDFFGKQLEDAITEVGIDAAGLLKDDKVHTTLALVHTYPDGDRDFSF
                     YRNPGADMMLTEEELPEEIIRGAKIFHFGTLSMTHPGVRAATKKAIAVAKEAGALISF
                     DPNIRKPLWDSMEDAREQVLYGLGQCDILKISDNEIQWLTGKEDYTDGVRWIRERYPV
                     PLILVSMGKEGSRAYYKDRIVEAKPFLQPNTIETTGAGDTFCACVLHYVLEHGLEGLE
                     EKNLKEMLRFANAAASLITTRKGALRVMPEKEEIEKML"
     gene            complement(968..2434)
                     /locus_tag="M72_RS04735"
                     /old_locus_tag="M72_24121"
     CDS             complement(968..2434)
                     /locus_tag="M72_RS04735"
                     /old_locus_tag="M72_24121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008372974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="WP_055067379.1"
                     /translation="MSEMLKKARAYEAEKAAQTDKNTRPLFHISAPAGWINDPNGFSV
                     YDGKIHLFYQYYPYAREWGPMHWGHSVTTDMISWEQLPAALAPDQDYDRNGCFSGSAI
                     EADNKHVLVYTGVTKITLPDGREEERQNQCIAFGDGRDYVKYENNPVVTGEMLPENCS
                     RIDFRDPKIWKEEDTYYLIVGSKDNRQIGQVVLCSSKDLKEWKFETVLAANSTGKVGT
                     MWECPDFFPLGDKHVLICSPQNMKAEKYEFHNGNNSVYFLGNYDKNSHIFEKEEPHTI
                     DYGLDFYAPQTTLLPDGRRVMIAWMKSWDACVVPDTQDWQGMMTLPRELEVKDGQIWQ
                     QPVREIAQYHKNPCHYEHAEIDGETALSGICGRTMDLTVTMDEQDFNVFSIQLAADEE
                     YETSFTYHKGTGILEIDRTYCGVTKDVVCVRKIKIADPKGLKKMRFILDRQSIELFIN
                     DGQQVATTAVCTPLEAEGIRFFSDKKMYITVEKYDIIL"
     gene            complement(2449..4128)
                     /locus_tag="M72_RS04740"
                     /old_locus_tag="M72_24131"
     CDS             complement(2449..4128)
                     /locus_tag="M72_RS04740"
                     /old_locus_tag="M72_24131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019160361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_055067380.1"
                     /translation="MWKRKIKKCLALGLAFAMMTGVAGCGKEQHLEAEINPDIPVSEV
                     QFPLKEQAELSFITSAPATSTQNPNERIIFKRLEKQTNVHIDWTCFVADQFSDKKNLA
                     LAQFGNLPDGLFNAGMSDYDLLRYAKQGIIIPLENLIDKYMPNLQAVFEKYPEYRTMC
                     TAPDGHIYSFPWIEQLGAGKEAIQAIGDIPYINKKWLDYLGLDIPTTTDELEQVLIAF
                     RDHADDLKKQFDIEGDVIPMSFIINNGDQDPAILINGFGEGYGDTGDHFAVKDDGTVI
                     YTTVQEGYKEGIEWLHKLVTEDLVDPEAFTQEWSTYVAKGKNHRYGLCFTWDIANIDN
                     NTDYVMLPALTGPEGARNITRQNNSETSGFDRGRCVLTSSCRNTALAAAWIDQMYAPL
                     QSPQNNWGSYGEKDSFNIFELSTNKDGGEMLKHLDLGDQSPVEVREAQSVNGPLAVLN
                     EYYDVYVTQPADAKWRLDNMHETYLKDMKSKYVYPNVFMSIDDTNKVSQYDTDIKKYA
                     EQKKADWILNGGIDKEWDSYLKKMEKYGLSDYLAIKQKYFDQYQESLKEEK"
     gene            complement(4150..5046)
                     /locus_tag="M72_RS04745"
                     /old_locus_tag="M72_24141"
     CDS             complement(4150..5046)
                     /locus_tag="M72_RS04745"
                     /old_locus_tag="M72_24141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004841831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_022045551.1"
                     /translation="METVSKMKYSRTDRLVLGIGYAILGLFVLSIVVPLVYVVLASFM
                     DPTVLNNQGLSFHIKDWTLDAYRRVLENGMIWRGFLNSFLYSLAFAAISVFVTLLAAY
                     PMSKKEFVGRKFFNVIFLITMFFGGGMIPTFILINQLHMVNTVWAILIPGAFNVWNMI
                     LARTYYQSIPKELREASAIDGANEIQHFFQIMMPVCKPIIAVLALWSFVGMWNSYFDA
                     MIYLNDANLQPLQLVLRSILVQNTPQPGMIADIQSTAEMAKVAEQLKYATIVVSSLPL
                     LIMYPFFQKYFDKGVMVGSVKG"
     gene            complement(5059..5997)
                     /locus_tag="M72_RS04750"
                     /pseudo
     CDS             complement(5059..5997)
                     /locus_tag="M72_RS04750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016441357.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
     gene            6217..7242
                     /locus_tag="M72_RS04755"
                     /old_locus_tag="M72_24171"
     CDS             6217..7242
                     /locus_tag="M72_RS04755"
                     /old_locus_tag="M72_24171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015517682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="WP_022045553.1"
                     /translation="MGKKQVTFADIAAYTNFSKTTISRYFNHPDSLTLENQEKISQAL
                     DTLGYKKNKLAKVLANGKSEFIGIIIPNLYLHYYSEMLTQILSSYRDFHYKFLVFVSD
                     NGPSEEEQYIDELMAYQIEGLIVLSHTLSSEKLASYQIPVIAIEREAEHICGVTSDNY
                     MGALQAATLLIRDKCDVLIHVNADVPKSIPAYDRIRAFEDTCQEYHVPYELNLNVIGD
                     SYQDIFAQMKHIFSDIDEKYPCKKKGIFLANDTYANMFLNLIFQKYGCFPDSYELVGF
                     DNSPIASEAILPITTVGQQIDLIAKTAIELLVQQMEERKKRRPVPLSEPIHKQITPVL
                     IRRDTTS"
ORIGIN      
        1 ttatagcatt ttttcaattt cttctttctc cggcatcacg cggagcgcgc ctttgcgcgt
       61 cgtgatcaga gaagccgccg cattggcaaa acgaagcatc tctttcaaat ttttctcttc
      121 aagcccctcc agtccatgct ccagcacata atgcagaaca cacgcacaga acgtatctcc
      181 cgcaccggtc gtctcaatcg tatttggctg aagaaacggc tttgcctcca caattctgtc
      241 tttataatac gcccggcttc cctcttttcc catggaaacc agtatgagcg gaaccggata
      301 gcgttcccgt atccagcgga ctccatccgt ataatcttct ttccccgtca gccactggat
      361 ttcattatcc gatattttta aaatatcaca ctgtcccaga ccatataaca cctgttccct
      421 ggcatcttcc atggagtccc agagcggttt gcggatattc ggatcaaagg aaatgagtgc
      481 acctgcttct tttgcgaccg cgatcgcttt tttcgttgct gcgcggacac ccggatgcgt
      541 catggacaac gttccaaaat gaaagatttt tgctccacgg attatttcct ccggcagttc
      601 ttcttccgtc agcatcatgt ccgcaccagg attacggtaa aaggaaaaat cccggtctcc
      661 atccggatac gtatgtacca gtgccagcgt cgtgtgcacc ttgtcatcct ttaaaagtcc
      721 ggctgcatca ataccgactt ccgtgatcgc atcttccagc tgctttccga aaaaatcgtt
      781 tcctactttt ccgataaaag ccgtcttatg tcccaggcgc gacagcattg ccagcacatt
      841 gcacggtgcg cctcccggat ttgcctcaaa cagcggattg ccctgcccgc tgactccgtt
      901 ttcggtaaaa tcaatgagca gttcccccaa agccactacg tccatgttct cttcctcctg
      961 ttacttttta taatataata tcatactttt cgaccgtaat atacatcttt ttatcgctga
     1021 aaaaccggat tccctctgcc tccaaagggg tacaaaccgc cgttgttgcc acctgctgcc
     1081 cgtcattgat aaaaagctca atggactgac ggtccagaat aaaccgcatt tttttaagtc
     1141 cttttggatc tgcaatttta attttgcgca cgcagaccac atcttttgtc acaccacagt
     1201 atgtgcggtc aatctccaat attcctgttc ccttatgata agtaaaactt gtctcgtatt
     1261 cctcatctgc ggcaagctgt atggaaaaaa cgttaaaatc ctgttcatcc attgtaacag
     1321 tcagatccat cgtccgtccg caaatgccgg aaagtgctgt ctcaccatca atctctgcat
     1381 gctcataatg gcacggattc ttatgatact gcgcaatctc ccgaaccggc tgctgccaga
     1441 tctgtccgtc ttttacttcc agttcccgcg gaagagtcat catgccctgc cagtcctgcg
     1501 tatccggcac cacacaggca tcccatgact tcatccatgc aatcatcaca cgccgcccat
     1561 ccgggagaag tgtggtctga ggtgcataaa agtccagtcc gtagtcaatc gtatgcggtt
     1621 cttctttttc aaatatatgc gaatttttat cgtaatttcc aagaaaataa acagaattat
     1681 ttccattgtg gaattcgtat ttttccgctt tcatattctg tggggaacag atcagtacat
     1741 gtttatctcc cagtgggaaa aagtccggac attcccacat cgttccgact tttccggtac
     1801 tgtttgccgc aagaacggtc tcaaatttcc attcttttaa atctttgctg gaacagagca
     1861 cgacctgtcc gatctgcctg ttatccttgc ttccgacaat cagataatag gtgtcctctt
     1921 ccttccagat tttcgggtca cggaaatcaa tccggctaca gttttccggc agcatctccc
     1981 cggtcacaac cgggttgttt tcatacttta cataatccct gccatccccg aatgcgatgc
     2041 actggttctg tcgttcctct tccctgccgt ccggcagtgt aatctttgtg acaccggtat
     2101 agaccagcac atgtttgtta tccgcttcaa tagcacttcc ggaaaaacat ccgttccggt
     2161 catagtcctg atccggtgca agtgctgccg gaagctgttc ccagcttatc atatccgttg
     2221 tcacactgtg cccccagtgc atcggtcccc actcccttgc atatggataa tactggtaga
     2281 acagatggat ttttccatcg taaacggaaa aaccgttcgg atcattgatc catccggcag
     2341 gtgccgagat atgaaacaac ggtctggtat ttttatcggt ctgtgctgct ttttctgcct
     2401 catatgctct cgcttttttt aacatctcac tcatacaaat tctcctgttt atttttcttc
     2461 tttcaatgac tcctgatact gatcgaaata tttctgtttg attgccagat aatcggaaag
     2521 cccgtatttc tccattttct ttaaatagga atcccactct ttgtcgattc cgccatttaa
     2581 aatccagtct gcttttttct gctccgcata ttttttaata tcggtatcat actgggatac
     2641 tttattggta tcgtcaatac tcataaacac attcggatat acatacttgc ttttcatatc
     2701 cttcagatat gtttcatgca tattgtccag acgccattta gcatccgccg gctgtgtgac
     2761 atacacatca taatactcat tgagaactgc aagcggaccg ttgacagact gcgcctcacg
     2821 tacctctacc ggtgactggt cgcccagatc cagatgcttc aacatttcac cgccatcttt
     2881 atttgtggac agttcaaaaa tattaaacga atccttttcc ccataacttc cccagttatt
     2941 ctgcggggac tgaagcggcg catacatctg atcaatccaa gctgccgcca gtgccgtgtt
     3001 ccgacagctg gatgtaagca cacagcggcc tctgtcaaaa ccacttgttt cactgttatt
     3061 ctgtcttgtg atatttctgg ctccctccgg accggtcagt gccggaagca tcacataatc
     3121 ggtattattg tcaatatttg caatatccca ggtaaagcag agaccgtaac ggtgattttt
     3181 accttttgcc acataggttg accactcctg cgtaaatgcc tccggatcta caagatcctc
     3241 tgttaccagc ttatgcagcc attcgatgcc ttctttgtaa ccttcctgca cggtcgtata
     3301 aatcacggtt ccgtcatctt ttacggcaaa atgatcgccc gtatctccat atccttcgcc
     3361 aaatccgttg atgagaatcg ccggatcctg atcgccattg ttgatgataa atgacatcgg
     3421 aatcacatct ccctcgatat caaactgttt tttcagatca tccgcatgat cccggaacgc
     3481 aatcagcacc tgttccagtt catcggttgt cgttggaata tccagtccca gataatccag
     3541 ccacttttta ttgatataag gaatatcccc gattgcctga atggcttctt tccctgcgcc
     3601 aagctgctca atccacggaa atgaataaat atgtccgtcc ggtgcggtac acatcgtccg
     3661 gtattccgga tatttctcaa agaccgcctg aaggtttggc atatatttgt caatcagatt
     3721 ttccagcgga ataataattc cctgctttgc ataacgaagc agatcataat cgctcattcc
     3781 tgcattaaac aaaccatccg gaaggtttcc aaactgtgcc agtgccagat tctttttatc
     3841 ggaaaactgg tctgccacaa aacaggtcca gtcaatatgt acattcgtct gtttttcgag
     3901 tctcttaaaa ataatccgct cgttcggatt ctgcgtagag gttgccggag cacttgtgat
     3961 aaatgataat tctgcctgtt ctttcagtgg aaactgtact tctgaaaccg gtatatccgg
     4021 attgatctct gcctccagat gctgctcttt tccgcatcct gccacaccgg tcatcatagc
     4081 aaatgccagt ccgagtgcca gacatttttt aatttttctc ttccacatat ctgtacctgt
     4141 cctttctgct taacctttta ccgatccaac cataacacct ttgtcaaagt atttctggaa
     4201 aaatggatac ataataagca atggtaaact tgatactaca attgttgcgt attttaactg
     4261 ttcggcaact tttgccatct ccgcggtact ctgaatgtcc gcgatcatgc ccggctgcgg
     4321 tgtattctgt accagaatgg aacgcagaac cagctgcagt ggctgtaagt ttgcatcatt
     4381 taagtaaatc atcgcatcaa aataactgtt ccacataccg acaaaagacc acagtgccag
     4441 caccgcgata atcggtttgc acaccggcat cataatctgg aagaaatgct ggatctcatt
     4501 tgccccgtca attgcggatg cctcccgcag ttcttttgga atggactgat agtacgttct
     4561 tgccagaatc atattccaga cattaaatgc tcccggaatg agaattgccc acacggtatt
     4621 taccatatga agctgattga tcaaaataaa cgtcgggatc attccaccgc cgaaaaacat
     4681 ggtaatcaga aaaatcacgt taaaaaattt tcttccgaca aattcttttt tcgacatcgg
     4741 atacgctgct aacaatgtga caaatacgga aattgccgca aatgccagtg aatacaaaaa
     4801 cgaatttaaa aatccgcgcc agatcattcc gttttccagc acacgccggt atgcatccag
     4861 tgtccagtct ttgatgtgaa aactcagtcc ctgattattc aataccgtcg ggtccataaa
     4921 agatgctaaa acaacataga ccagcggaac aacaattgaa agaacaaaca gtccaagaat
     4981 ggcataaccg attccaagca ccagccggtc tgtccgtgaa tatttcattt tactaactgt
     5041 ttccatttca cgttcctcct ataatccttc tccatcgttt aattttttta ccacccagtt
     5101 cacaaatata agcaggatca cattgatcac cgaattaaac agtcccactg ccgtagaata
     5161 accgtaatcg ccattcaaaa gaccaatccg gtatacatag gttgataaaa tttcagaagc
     5221 cggtaagttc atatctgtct gcagggcata tgccttttca aagccgatgc tcataatgtt
     5281 tccggcctgt aaaataaact ggatcacgat aatatccttg attgccggaa gttccacata
     5341 ccagatctgc tgcaaaagat ttgcaccgtc cacaatggct gcctcttcca gttccttgct
     5401 tgcattggat aatgctgcag tatacatgat ggatgcccag cctgctccct gccagattcc
     5461 gcttgcaata taaatggtac ggaatgcgga cggcatggtc atccagtttg tattcatccc
     5521 caacaggcgg tttaacggtc ctaccggaga taaaaacata cgcaccatac cacagagcac
     5581 gatgacggaa ataaaattcg gtgcatagat cagcagctag atttttttct taatccccgc
     5641 cttgcggata cggttcagta aaagtgccag aataattggt atcggaaaac tccagagaag
     5701 tccaaagata ctcagcttta atgtgttcag caggtagttc ataaaatccg gtgatgataa
     5761 aaatctccgg aaatattcca gccccaccca cgggcttccc aaaactcctt taatgacatt
     5821 gtaatcctca aatgcaatca gaagtcctcc catcggaaga tacttgaata tgattgtgag
     5881 taacagtgcc ggcatcagga aaaaaacata cagctgccag tttttcttta tataagacag
     5941 cttactcccc atggtttgtt ttttcgcaga gccgacttgt tttgccagtt ttttcatgcg
     6001 attgctcctc ccttttcatc gtattactcg ttctgctttg gtgtaaccgg taaagtaacc
     6061 ggttacttta tattctgata gtactacaaa gtttccgata tgtcaacact tttatttatt
     6121 aaagtaaccg attacgtaac tagttatttt ttcattgcta tttttctttc cggttgttat
     6181 actatggata aaacagataa aggagacagc tttcagatgg gaaagaaaca ggtaacattt
     6241 gcagatattg cagcatatac gaatttttca aagacaacca tttccagata ttttaatcat
     6301 ccggactccc tgacgcttga aaatcaggag aaaatttcac aggctcttga tactctgggt
     6361 tacaaaaaga ataagcttgc aaaggttctt gccaatggaa agagtgaatt tatcggaatc
     6421 attattccga acctttatct gcactattat tcggaaatgc ttacacagat tctttccagc
     6481 taccgcgatt ttcattataa atttctcgta ttcgtcagcg acaacggacc gtccgaggag
     6541 gaacagtaca ttgatgaact gatggcatac cagattgagg gcctgatcgt gttaagtcac
     6601 actctttctt ccgaaaaact ggcttcttac cagatccctg tcattgccat tgagcgcgaa
     6661 gctgaacata tctgtggcgt aaccagcgac aattatatgg gtgcgctcca ggcggcaacg
     6721 cttctgatcc gagacaaatg cgatgtactg attcacgtta atgcggatgt tccaaagtcc
     6781 atccctgcct atgaccgtat ccgtgccttt gaagatacct gtcaggaata tcacgttcct
     6841 tatgaactga atttaaatgt aataggggat tcttatcagg acatttttgc acaaatgaag
     6901 cacattttct ctgatattga tgagaagtat ccatgcaaaa aaaaggggat tttcctcgcc
     6961 aatgatacct atgcaaatat gtttttaaac ctgattttcc aaaaatacgg atgctttcct
     7021 gacagttatg aactggtcgg atttgacaat tccccgattg caagcgaggc aattctgcct
     7081 atcacaacgg tcggacagca gatcgacctg atcgccaaaa ccgcaataga acttctggta
     7141 cagcagatgg aagaacgcaa aaaaagaaga ccggttcctc tttcggaacc gatccataaa
     7201 cagattacac cggtactgat ccgcagggat acgaccagct ga
//

