| Basic Information | |
|---|---|
| Species | Malus domestica |
| Cazyme ID | MDP0000230423 |
| Family | GT16 |
| Protein Properties | Length: 405 Molecular Weight: 46361.5 Isoelectric Point: 8.5353 |
| Chromosome | Chromosome/Scaffold: 019184124 Start: 23873 End: 25157 |
| Description | beta-1,2-N-acetylglucosaminyltransferase II |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
 | |||
| Family | Start | End | Evalue |
| GT16 | 283 | 396 | 2.4e-40 |
| KIHKKSSEFCFFDEYNWDITMWATVYPSFGNPVFTLRGPRTSAVHFGKCGLHQGQGEAKTCIDNGMVNFDVEEIDKVANINSDWEVQVFKNQPGYQAGFK GWGGWGDKRDHQLC | |||
| GT16 | 81 | 277 | 0 |
| LEXRNQMPPRNLDLYPSLAKDHITIVLYVHNRPQYLKVAVDSLSRVVGINETLLIVSHDGFFEEMNKVVEGIRFCQVKQIFAPYSPHVFPNSFPGXSSTD CKGKDDAKAKHCKGTPDQYGNHRSPKIVSLKHHWWWMMNTVWDGLKETKDHNGHILFIEEDHYIYPNAYRNLQILTELKPHKCPHCYAANLAPCNVN | |||
| Full Sequence |
|---|
| Protein Sequence Length: 405 Download |
| MAIIKKQRLK DKAAFRRFLP VVSITLLGVF LLMFLLRFNS SSNFVTPPSD DFDEVSIRSG 60 SRSHVRQILS LPKQTELSVQ LEXRNQMPPR NLDLYPSLAK DHITIVLYVH NRPQYLKVAV 120 DSLSRVVGIN ETLLIVSHDG FFEEMNKVVE GIRFCQVKQI FAPYSPHVFP NSFPGXSSTD 180 CKGKDDAKAK HCKGTPDQYG NHRSPKIVSL KHHWWWMMNT VWDGLKETKD HNGHILFIEE 240 DHYIYPNAYR NLQILTELKP HKCPHCYAAN LAPCNVNAKG EGKIHKKSSE FCFFDEYNWD 300 ITMWATVYPS FGNPVFTLRG PRTSAVHFGK CGLHQGQGEA KTCIDNGMVN FDVEEIDKVA 360 NINSDWEVQV FKNQPGYQAG FKGWGGWGDK RDHQLCLSFA QMYHS |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam05060 | MGAT2 | 2.0e-159 | 78 | 396 | 364 | + N-acetylglucosaminyltransferase II (MGAT2). UDP-N-acetyl-D-glucosamine:alpha-6-D-mannoside beta-1,2-N- acetylglucosaminyltransferase II (EC 2.4.1.143) (GnT II/MGAT2) is a Golgi resident enzyme that catalyzes an essential step in the biosynthetic pathway leading from high mannose to complex N-linked oligosaccharides. Mutations in the MGAT2 gene lead to congenital disorder of glycosylation (CDG IIa). CDG IIa patients have an increased bleeding tendency, unrelated to coagulation factors. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0005795 | Golgi stack |
| GO:0008455 | alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity |
| GO:0009312 | oligosaccharide biosynthetic process |
| GO:0016021 | integral to membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CAI72505.1 | 0 | 66 | 404 | 67 | 427 | beta 1,2 N-acetylglucosaminyltransferase [Populus alba x Populus tremula] |
| EMBL | CAN61074.1 | 0 | 1 | 404 | 1 | 426 | hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002268643.1 | 0 | 1 | 404 | 1 | 426 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002321199.1 | 0 | 42 | 404 | 42 | 427 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002530215.1 | 0 | 39 | 405 | 39 | 427 | beta-1,2-n-acetylglucosaminyltransferase II, putative [Ricinus communis] |
