Basic Information | |
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Species | Malus domestica |
Cazyme ID | MDP0000862557 |
Family | GT8 |
Protein Properties | Length: 362 Molecular Weight: 39918 Isoelectric Point: 5.3017 |
Chromosome | Chromosome/Scaffold: 013257111 Start: 1901 End: 2986 |
Description | Nucleotide-diphospho-sugar transferases superfamily protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT8 | 73 | 334 | 3.99931e-42 |
QAVHVAMTLDTAYIRGSMAAILSVLQHSSCPQNAVFHFVASAAANASLLRQTISTSFPYLKFRIYAFDDSHVSGLISTSIRSALDCPLNYARSYLADLLP LCVRRVVYLDSDLILVDDIAKLSATPLGXVAVLAAPEYCNANFTSYFTSAFWSNPSLSLTFADRHACYFNTGVMVIDLDRWRGDDYTAKIEEWMELQKRM RIYELGSLPPFLLVFAGKIAPVEHRWNQHGLGGDNFRGLCRDLHPGAVSLLHWSGKGKPWAR |
Full Sequence |
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Protein Sequence Length: 362 Download |
MPMPPPLLLL LXLLLFLSPA TATNAAAAAA TTQQFREAPQ FYNSQDCPSI XTLPDVDVDP 60 DESDDGHMIC SPQAVHVAMT LDTAYIRGSM AAILSVLQHS SCPQNAVFHF VASAAANASL 120 LRQTISTSFP YLKFRIYAFD DSHVSGLIST SIRSALDCPL NYARSYLADL LPLCVRRVVY 180 LDSDLILVDD IAKLSATPLG XVAVLAAPEY CNANFTSYFT SAFWSNPSLS LTFADRHACY 240 FNTGVMVIDL DRWRGDDYTA KIEEWMELQK RMRIYELGSL PPFLLVFAGK IAPVEHRWNQ 300 HGLGGDNFRG LCRDLHPGAV SLLHWSGKGK PWARLEANRP CPLDALWAPY DLLETPFVLD 360 S* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
PLN02829 | PLN02829 | 3.0e-20 | 160 | 350 | 191 | + Probable galacturonosyltransferase | ||
PLN02742 | PLN02742 | 1.0e-20 | 160 | 360 | 202 | + Probable galacturonosyltransferase | ||
cd04194 | GT8_A4GalT_like | 4.0e-26 | 75 | 332 | 272 | + A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The members of this family of glycosyltransferases catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The enzymes exhibit broad substrate specificities. The known functions found in this family include: Alpha-1,4-galactosyltransferase, LOS-alpha-1,3-D-galactosyltransferase, UDP-glucose:(galactosyl) LPS alpha1,2-glucosyltransferase, UDP-galactose: (glucosyl) LPS alpha1,2-galactosyltransferase, and UDP-glucose:(glucosyl) LPS alpha1,2-glucosyltransferase. Alpha-1,4-galactosyltransferase from N. meningitidis adds an alpha-galactose from UDP-Gal (the donor) to a terminal lactose (the acceptor) of the LOS structure of outer membrane. LOSs are virulence factors that enable the organism to evade the immune system of host cells. In E. coli, the three alpha-1,2-glycosyltransferases, that are involved in the synthesis of the outer core region of the LPS, are all members of this family. The three enzymes share 40 % of sequence identity, but have different sugar donor or acceptor specificities, representing the structural diversity of LPS. | ||
cd06429 | GT8_like_1 | 3.0e-29 | 75 | 335 | 279 | + GT8_like_1 represents a subfamily of GT8 with unknown function. A subfamily of glycosyltransferase family 8 with unknown function: Glycosyltransferase family 8 comprises enzymes with a number of known activities; lipopolysaccharide galactosyltransferase lipopolysaccharide glucosyltransferase 1, glycogenin glucosyltransferase and inositol 1-alpha-galactosyltransferase. It is classified as a retaining glycosyltransferase, based on the relative anomeric stereochemistry of the substrate and product in the reaction catalyzed. | ||
pfam01501 | Glyco_transf_8 | 1.0e-59 | 76 | 335 | 263 | + Glycosyl transferase family 8. This family includes enzymes that transfer sugar residues to donor molecules. Members of this family are involved in lipopolysaccharide biosynthesis and glycogen synthesis. This family includes Lipopolysaccharide galactosyltransferase, lipopolysaccharide glucosyltransferase 1, and glycogenin glucosyltransferase. |
Gene Ontology | |
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GO Term | Description |
GO:0016757 | transferase activity, transferring glycosyl groups |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ABK94510.1 | 0 | 33 | 361 | 35 | 362 | unknown [Populus trichocarpa] |
GenBank | ACW83060.1 | 0 | 23 | 361 | 25 | 362 | glycosyltransferase family GT8 protein [Populus deltoides] |
RefSeq | XP_002302469.1 | 0 | 29 | 360 | 22 | 352 | glycosyltransferase, CAZy family GT8 [Populus trichocarpa] |
RefSeq | XP_002326899.1 | 0 | 33 | 361 | 33 | 360 | glycosyltransferase family GT8 [Populus trichocarpa] |
RefSeq | XP_002510336.1 | 0 | 10 | 361 | 7 | 356 | transferase, transferring glycosyl groups, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 1ga8_A | 0.00002 | 162 | 334 | 84 | 254 | A Chain A, Catalytic Function And Substrate Recognition Of The Pectate Lyase From Thermotoga Maritima |
PDB | 1g9r_A | 0.00002 | 162 | 334 | 84 | 254 | A Chain A, Crystal Structure Of Galactosyltransferase Lgtc In Complex With Mn And Udp-2f-Galactose |
PDB | 1ss9_A | 0.00003 | 162 | 334 | 84 | 254 | A Chain A, Crystal Structural Analysis Of Active Site Mutant Q189e Of Lgtc |