| Basic Information | |
|---|---|
| Species | Physcomitrella patens |
| Cazyme ID | Pp1s4763_1V6.1 |
| Family | GH29 |
| Protein Properties | Length: 190 Molecular Weight: 20924.2 Isoelectric Point: 5.2809 |
| Chromosome | Chromosome/Scaffold: 4763 Start: 190 End: 759 |
| Description | |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GH29 | 2 | 134 | 2.6e-26 |
| RALQPDILINNRLGYSAAHDGYRADGGVGAGDSDTLGDFGTPEHVIHAEQKRLWESCQVTTWRLWSHVIGERWRPADVLLDMLCESAEKGGGHGGNLLLN VGPAADGQLPPEFVERGLEIGRWLEVHGEAVYG | |||
| Full Sequence |
|---|
| Protein Sequence Length: 190 Download |
| MRALQPDILI NNRLGYSAAH DGYRADGGVG AGDSDTLGDF GTPEHVIHAE QKRLWESCQV 60 TTWRLWSHVI GERWRPADVL LDMLCESAEK GGGHGGNLLL NVGPAADGQL PPEFVERGLE 120 IGRWLEVHGE AVYGTDGGSV TEFITRGRQT TRGNNLYLII RFWDGRPDMR LADLXTRVKG 180 VTLLTTGQEL |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam01120 | Alpha_L_fucos | 1.0e-13 | 2 | 134 | 136 | + Alpha-L-fucosidase. | ||
| smart00812 | Alpha_L_fucos | 1.0e-14 | 4 | 163 | 171 | + Alpha-L-fucosidase. O-Glycosyl hydrolases (EC 3.2.1.-) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site. Because the fold of proteins is better conserved than their sequences, some of the families can be grouped in 'clans'. Family 29 encompasses alpha-L-fucosidases, which is a lysosomal enzyme responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. Deficiency of alpha-L-fucosidase results in the lysosomal storage disease fucosidosis. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004560 | alpha-L-fucosidase activity |
| GO:0005975 | carbohydrate metabolic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | YP_001559295.1 | 3e-18 | 1 | 190 | 209 | 396 | Alpha-L-fucosidase [Clostridium phytofermentans ISDg] |
| RefSeq | YP_003093102.1 | 3e-20 | 1 | 190 | 248 | 421 | Alpha-L-fucosidase [Pedobacter heparinus DSM 2366] |
| RefSeq | YP_003244503.1 | 0 | 1 | 190 | 195 | 383 | Alpha-L-fucosidase [Geobacillus sp. Y412MC10] |
| RefSeq | ZP_03708807.1 | 3e-20 | 1 | 187 | 381 | 548 | hypothetical protein CLOSTMETH_03568 [Clostridium methylpentosum DSM 5476] |
| RefSeq | ZP_03723991.1 | 0 | 1 | 190 | 205 | 379 | Alpha-L-fucosidase [Opitutaceae bacterium TAV2] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2wvv_B | 0.00000003 | 1 | 190 | 216 | 406 | B Chain B, Crystal Structure Of An Alpha-L-Fucosidase Gh29 From Bacteroides Thetaiotaomicron |
| PDB | 4j28_B | 0.00000003 | 1 | 190 | 216 | 406 | B Chain B, Crystal Structure Of An Alpha-L-Fucosidase Gh29 From Bacteroides Thetaiotaomicron |
| PDB | 4j28_A | 0.00000003 | 1 | 190 | 216 | 406 | B Chain B, Crystal Structure Of An Alpha-L-Fucosidase Gh29 From Bacteroides Thetaiotaomicron |
| PDB | 4j27_B | 0.00000003 | 1 | 190 | 216 | 406 | B Chain B, Crystal Structure Of An Alpha-L-Fucosidase Gh29 From Bacteroides Thetaiotaomicron |
| PDB | 4j27_A | 0.00000003 | 1 | 190 | 216 | 406 | B Chain B, Crystal Structure Of An Alpha-L-Fucosidase Gh29 From Bacteroides Thetaiotaomicron |
| Hydropathy |
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