Basic Information | |
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Species | Setaria italica |
Cazyme ID | Si027686m |
Family | GT29 |
Protein Properties | Length: 403 Molecular Weight: 44099.6 Isoelectric Point: 9.9534 |
Chromosome | Chromosome/Scaffold: 8 Start: 2202754 End: 2203962 |
Description | Glycosyltransferase family 29 (sialyltransferase) family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT29 | 164 | 379 | 0 |
RRERFPTCAVVGNSGILLGSGRGGQIDAHDLVVRLNNARVAGYAADVGAKTSLSFVNSNILHRCAVRSAVAAGGCACHPYGRAVPMAMYVCQPAHLLDAL ICNATATPASPFPLLVTDARLDALCARIAKYYSMRRFVATTGEPANNWTRRHDERYFHYSSGLQAVVMALGVCDEVSLFGFGKAAGAKHHYHTNQKKELD LHDYEAEYQFYRDLQA |
Full Sequence |
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Protein Sequence Length: 403 Download |
MKRRHLPPVL VLLLALSLLS LPFRRRLFLP RGPSQYYAGG DALLRRLAAA DAGGDQVRAE 60 AAALVANASV SSFPSIGNRY RLLYLRLPYH TNATSAPRQR AVSRLRVPFE TVPDDGALLA 120 AFRASLRSFL LARRQLRRRG GDDDDVVAGV AMGGIGDLLD RHPRRERFPT CAVVGNSGIL 180 LGSGRGGQID AHDLVVRLNN ARVAGYAADV GAKTSLSFVN SNILHRCAVR SAVAAGGCAC 240 HPYGRAVPMA MYVCQPAHLL DALICNATAT PASPFPLLVT DARLDALCAR IAKYYSMRRF 300 VATTGEPANN WTRRHDERYF HYSSGLQAVV MALGVCDEVS LFGFGKAAGA KHHYHTNQKK 360 ELDLHDYEAE YQFYRDLQAR PEAVPFFDET PGFKVPPVKL YW* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
cd12162 | 2-Hacid_dh_4 | 0.002 | 179 | 210 | 32 | + Putative D-isomer specific 2-hydroxyacid dehydrogenases. 2-Hydroxyacid dehydrogenases catalyze the conversion of a wide variety of D-2-hydroxy acids to their corresponding keto acids. The general mechanism is (R)-lactate + acceptor to pyruvate + reduced acceptor. Formate/glycerate and related dehydrogenases of the D-specific 2-hydroxyacid dehydrogenase superfamily include groups such as formate dehydrogenase, glycerate dehydrogenase, L-alanine dehydrogenase, and S-adenosylhomocysteine yydrolase. Despite often low sequence identity, these proteins typically have a characteristic arrangement of 2 similar subdomains of the alpha/beta Rossmann fold NAD+ binding form. The NAD+ binding domain is inserted within the linear sequence of the mostly N-terminal catalytic domain, which has a similar domain structure to the internal NAD binding domain. Structurally, these domains are connected by extended alpha helices and create a cleft in which NAD is bound, primarily to the C-terminal portion of the 2nd (internal) domain. Some related proteins have similar structural subdomain but with a tandem arrangement of the catalytic and NAD-binding subdomains in the linear sequence. While many members of this family are dimeric, alanine DH is hexameric and phosphoglycerate DH is tetrameric. | ||
pfam00777 | Glyco_transf_29 | 2.0e-31 | 167 | 377 | 223 | + Glycosyltransferase family 29 (sialyltransferase). Members of this family belong to glycosyltransferase family 29. |
Gene Ontology | |
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GO Term | Description |
GO:0006486 | protein glycosylation |
GO:0008373 | sialyltransferase activity |
GO:0030173 | integral to Golgi membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ACN30607.1 | 0 | 64 | 402 | 1 | 340 | unknown [Zea mays] |
GenBank | EAY82275.1 | 0 | 23 | 401 | 22 | 395 | hypothetical protein OsI_37484 [Oryza sativa Indica Group] |
RefSeq | NP_001066170.1 | 0 | 23 | 402 | 22 | 396 | Os12g0151500 [Oryza sativa (japonica cultivar-group)] |
RefSeq | NP_001150867.1 | 0 | 1 | 402 | 1 | 402 | sialyltransferase-like protein [Zea mays] |
RefSeq | XP_002449004.1 | 0 | 1 | 402 | 1 | 400 | hypothetical protein SORBIDRAFT_05g003160 [Sorghum bicolor] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 2wml_A | 2e-16 | 133 | 358 | 61 | 262 | A Chain A, Crystal Structure Of A Mammalian Sialyltransferase |
PDB | 2wnf_A | 3e-16 | 171 | 358 | 100 | 262 | A Chain A, Crystal Structure Of A Mammalian Sialyltransferase |
PDB | 2wnb_A | 3e-16 | 171 | 358 | 100 | 262 | A Chain A, Crystal Structure Of A Mammalian Sialyltransferase In Complex With Disaccharide And Cmp |