| Basic Information | |
|---|---|
| Species | Thellungiella halophila |
| Cazyme ID | Thhalv10020752m |
| Family | GT65 |
| Protein Properties | Length: 439 Molecular Weight: 49973.9 Isoelectric Point: 9.284 |
| Chromosome | Chromosome/Scaffold: 13 Start: 7893863 End: 7895179 |
| Description | O-fucosyltransferase family protein |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GT65 | 78 | 198 | 2.2e-36 |
| GLNNQKIAFARACLTARMMNRTLLMPSLSASLFYKEVDKLRPIPFDKVFQFERFNSMCSGFVRLARFSDVRNRTQVFDLEKGSGRRWTVERDLKQLKQSA GNGSIDEFEVIRIIGKNPFLW | |||
| GT65 | 197 | 381 | 0 |
| LWHDHWPVKDYAKVFECMVVVDEIAREADIVVMKIREALELRTGIQSPILFVAVHMRIEIDWMIHCKKLEQRKKVSEICSSKREIMERVGNISGLKTPTV LYLAVADSLLEEKEEDSSVLTGWRDGLIPFEKKKLGVKEEIYGKYSYLIQSAIDYEVCLRADVFVGNSYSTFSSLIVLERTQKAR | |||
| Full Sequence |
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| Protein Sequence Length: 439 Download |
| MNSPLSCKTL RLFSKSIACK CLVLVAIALF YRALMLSYSP RNALNSSSLI LARYMTDSSS 60 TGGIRTDKFL EVPQIVWGLN NQKIAFARAC LTARMMNRTL LMPSLSASLF YKEVDKLRPI 120 PFDKVFQFER FNSMCSGFVR LARFSDVRNR TQVFDLEKGS GRRWTVERDL KQLKQSAGNG 180 SIDEFEVIRI IGKNPFLWHD HWPVKDYAKV FECMVVVDEI AREADIVVMK IREALELRTG 240 IQSPILFVAV HMRIEIDWMI HCKKLEQRKK VSEICSSKRE IMERVGNISG LKTPTVLYLA 300 VADSLLEEKE EDSSVLTGWR DGLIPFEKKK LGVKEEIYGK YSYLIQSAID YEVCLRADVF 360 VGNSYSTFSS LIVLERTQKA RRLGFMSSCE DGENEWRSYA YNLAGESKGV PRRWMTNMTH 420 TNLQAISYGS NSVSCSSG* |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| cd11296 | O-FucT_like | 0.0003 | 69 | 117 | 49 | + GDP-fucose protein O-fucosyltransferase and related proteins. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. | ||
| cd11299 | O-FucT_plant | 3.0e-12 | 78 | 377 | 327 | + GDP-fucose protein O-fucosyltransferase, plant specific subfamily. Some members of this plant-specific family of O-fucosyltransferases have been annotated as auxin-independent growth promotors. The function of the protein seems unclear. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. | ||
| cd11296 | O-FucT_like | 3.0e-19 | 200 | 377 | 179 | + GDP-fucose protein O-fucosyltransferase and related proteins. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. | ||
| pfam10250 | O-FucT | 4.0e-46 | 78 | 381 | 335 | + GDP-fucose protein O-fucosyltransferase. This is a family of conserved proteins representing the enzyme responsible for adding O-fucose to EGF (epidermal growth factor-like) repeats. Six highly conserved cysteines are present in O-FucT-1 as well as a DXD-like motif (ERD), conserved in mammals, Drosophila, and C. elegans. Both features are characteristic of several glycosyltransferase families. The enzyme is a membrane-bound protein released by proteolysis and, as for most glycosyltransferases, is strongly activated by manganese. | ||
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAN72045.1 | 0 | 95 | 438 | 1 | 351 | unknown protein [Arabidopsis thaliana] |
| RefSeq | NP_187183.3 | 0 | 1 | 438 | 1 | 445 | unknown protein [Arabidopsis thaliana] |
| RefSeq | XP_002273827.1 | 0 | 17 | 435 | 1 | 427 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002332132.1 | 0 | 95 | 435 | 1 | 347 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002531235.1 | 0 | 8 | 435 | 8 | 446 | conserved hypothetical protein [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3zy6_A | 0.0003 | 247 | 381 | 213 | 349 | A Chain A, Structure Of Apo-Glycogenin Truncated At Residue 270 |
| PDB | 3zy5_A | 0.0003 | 247 | 381 | 213 | 349 | A Chain A, Structure Of Apo-Glycogenin Truncated At Residue 270 |
| PDB | 3zy4_A | 0.0003 | 247 | 381 | 213 | 349 | A Chain A, Structure Of Apo-Glycogenin Truncated At Residue 270 |
| PDB | 3zy3_B | 0.0003 | 247 | 381 | 213 | 349 | A Chain A, Structure Of Apo-Glycogenin Truncated At Residue 270 |
| PDB | 3zy3_A | 0.0003 | 247 | 381 | 213 | 349 | A Chain A, Structure Of Apo-Glycogenin Truncated At Residue 270 |
