| Basic Information | |
|---|---|
| Species | Volvox carteri |
| Cazyme ID | Vocar20002846m |
| Family | GT47 |
| Protein Properties | Length: 738 Molecular Weight: 78851.4 Isoelectric Point: 6.8136 |
| Chromosome | Chromosome/Scaffold: 2 Start: 3480567 End: 3487453 |
| Description | Exostosin family protein |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
 | |||
| Family | Start | End | Evalue |
| GT47 | 304 | 598 | 7.2e-25 |
| LLPARFAQHSGPWWLRQALAASLNVVHDIQKADIVYVDDFCYAAWSEAKLHDRGAWGPSEEMYVDPDIYLAAAFHLLLKHRSFRGTGGAQFVFFHSHPAL FLYHAVLCNPAFAAALHLVPEALVRQNCGPSRMLVVPYASFPFYHNPTAADVVADAVVATAAGASRVPSSSDPVRPRLLHFRGTCGGNSDGKALRRAVVE ALHDVSAPADATATETANASILASCESFTWEDLSLVELSKSRYCLILAGDTASSRRLSEAVLMGCVPVFLGPPFAATPLSGVVRYDAFALVFEVP | |||
| Full Sequence |
|---|
| Protein Sequence Length: 738 Download |
| MAKRATGGDV AVMAADMAAA AGSVNPDAAA AGGPGASPAG APMSPIEAKL AAVTQTFLND 60 MCSGLNREMA PHLPPEKVKE LASMHLAPDA VVHVDGLLHS VPPVTGPQAF FDFITLERAA 120 YRAMSLDTLL VAVSPTGDTV FALSRFKMKN VGPWHGKAAT RRISEGVRID ELRFDDTGGK 180 IIEAWCNRQL FQEERDLLLR EPDRHHPAVF DPALLAAVSP PEGGHGGLTA PDQLLRVAQI 240 WAETWNMASI AGPPDPDILD TLADHDFHLM DALGFTGDDA QSHPFTRSTI RNDDRASQHA 300 TRGLLPARFA QHSGPWWLRQ ALAASLNVVH DIQKADIVYV DDFCYAAWSE AKLHDRGAWG 360 PSEEMYVDPD IYLAAAFHLL LKHRSFRGTG GAQFVFFHSH PALFLYHAVL CNPAFAAALH 420 LVPEALVRQN CGPSRMLVVP YASFPFYHNP TAADVVADAV VATAAGASRV PSSSDPVRPR 480 LLHFRGTCGG NSDGKALRRA VVEALHDVSA PADATATETA NASILASCES FTWEDLSLVE 540 LSKSRYCLIL AGDTASSRRL SEAVLMGCVP VFLGPPFAAT PLSGVVRYDA FALVFEVPTA 600 SATWLRRHRR QLQQQHHHHH RQPLFVDAVS GHPFDDDGGG GGGGGGGGGG RGIGIQRFAT 660 RLTALQDLPA ALHAIGRRRY AAMSYNLAAV RPFFSFVADP DGGPLAGLND VLYSRMCFHA 720 AGGPEATARR AHLPGKV* |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 6.0e-8 | 311 | 597 | 297 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAC18793.1 | 0.0000007 | 311 | 623 | 96 | 422 | End is cut off [Arabidopsis thaliana] |
| GenBank | ABK24530.1 | 0.0000003 | 310 | 627 | 109 | 410 | unknown [Picea sitchensis] |
| RefSeq | NP_176908.2 | 0.0000005 | 311 | 623 | 96 | 392 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_001696600.1 | 0.0000003 | 76 | 192 | 63 | 204 | hypothetical protein CHLREDRAFT_167348 [Chlamydomonas reinhardtii] |
| RefSeq | XP_002512333.1 | 0.00000003 | 310 | 623 | 100 | 394 | catalytic, putative [Ricinus communis] |
| Hydropathy |
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