Basic Information | |
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Species | Fragaria vesca |
Cazyme ID | mrna31235.1-v1.0-hybrid |
Family | GT47 |
Protein Properties | Length: 527 Molecular Weight: 59615.8 Isoelectric Point: 7.288 |
Chromosome | Chromosome/Scaffold: 2 Start: 7806986 End: 7808898 |
Description | Exostosin family protein |
View CDS |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 194 | 474 | 0 |
RLFKIYVYQEGDPPIFHNGPCKSIYSTEGMFIHEMEMDNTYRTKNPDDALVYFLPFSVVMLVQYLYEAESHSTESIGRAVVDYVNVISDKHPFWNRSLGA DHFMLSCHDWGPRTSSYVPQLYHKSIRVLCNANTSEGFNPSKDVSFPEIHLRTGETKGLLGGLSPSRRSVLAFFAGRLHGHIRCLLLNEWKEKDQDVQVY DQLPNGVSYESMLKQSKFCLCPSGYEVASPRIVEAIYAECVPVLISDNYVPPFSDVLEWKTFSVQVQVKDIPNIKTILMGI |
Full Sequence |
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Protein Sequence Length: 527 Download |
MKPLTNKPSL FPPFWSSSTS YSSSSAFILV LVALVCTLGV TVSFSWSWRV NTVLGTGYSS 60 SLAFSTKSRP NSQVVNEEAA PEAHPIVSPS NDSEPNGTVH LPHSQIVEKQ EVAVLNDKES 120 GEINATTASE TITIKRYSRL EKLEASLAGV RASIREAARV RNLTSTHEDP DYVPQGPIYR 180 NANAFHRSYL EMERLFKIYV YQEGDPPIFH NGPCKSIYST EGMFIHEMEM DNTYRTKNPD 240 DALVYFLPFS VVMLVQYLYE AESHSTESIG RAVVDYVNVI SDKHPFWNRS LGADHFMLSC 300 HDWGPRTSSY VPQLYHKSIR VLCNANTSEG FNPSKDVSFP EIHLRTGETK GLLGGLSPSR 360 RSVLAFFAGR LHGHIRCLLL NEWKEKDQDV QVYDQLPNGV SYESMLKQSK FCLCPSGYEV 420 ASPRIVEAIY AECVPVLISD NYVPPFSDVL EWKTFSVQVQ VKDIPNIKTI LMGISQSQYL 480 RMHRRVKLVQ RHFVVNGPSK RYDVFNMIVH SIWLRRLNIR IEDQLE* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-64 | 192 | 474 | 302 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |