Curated by Yanbin Yin and Xinpeng Zhang (June 2022) Substrate_Simple_V2 Family Name EC_Number - GH0 Glycoside hydrolases not yet assigned to a family. - 5-Hydroxyisourate (uric acid) GH1 hydroxyisourate hydrolase 3.-.-.- beta-glucan GH1 beta-glycosidase 3.2.1.- rutin (polyphenol) GH1 "beta-rutinosidase /alpha-L-rhamnose-(1,6)-beta-D-glucosidase" 3.2.1.- Strictosidine (monoterpene indole alkaloids) GH1 strictosidine beta-glucosidase 3.2.1.105 "lactose in milk, phlorizin (polyphenols) in fruit" GH1 lactase 3.2.1.108 amygdalin (cyanogenic glycosides) GH1 amygdalin beta-glucosidase 3.2.1.117 prunasin (cyanogenic glycosides) GH1 prunasin beta-glucosidase 3.2.1.118 vicianin (cyanogenic glycosides) GH1 vicianin hydrolase 3.2.1.119 Raucaffricine (glucoalkaloid) GH1 raucaffricine beta-glucosidase 3.2.1.125 glucosinolates (sulfur-containing phytochemicals) GH1 thioglucosidase 3.2.1.147 ¦Â-primeverosides (tea plant phytochemicals) GH1 beta-primeverosidase 3.2.1.149 "Daidzin and genistin, Furcatin (polyphenol)" GH1 isoflavonoid 7-O-beta-apiosyl-beta-glucosidase 3.2.1.161 abscisic acid (plant) GH1 ABA-specific beta-glucosidase 3.2.1.175 DIMBOA glucoside (polyphenol) GH1 DIMBOA beta-glucosidase 3.2.1.182 Furostanol (polyphenol) GH1 protodioscin 26-O-¦Â-D-glucosidase 3.2.1.186 beta-D-glucoside GH1 beta-glucosidase 3.2.1.21 beta-D-galactoside GH1 beta-galactosidase 3.2.1.23 beta-D-mannoside GH1 beta-mannosidase 3.2.1.25 beta-D-glucuronoside GH1 beta-glucuronidase 3.2.1.31 "beta-D-glucoside, beta-D-xyloside" GH1 beta-xylosidase 3.2.1.37 beta-D-fucosides GH1 beta-D-fucosidase 3.2.1.38 phlorizin (polyphenols) in fruit GH1 phlorizin hydrolase 3.2.1.62 beta-D-glucoside GH1 "exo-beta-1,4-glucanase" 3.2.1.74 6-phospho-beta-D-galactoside GH1 6-phospho-beta-galactosidase 3.2.1.85 6-phospho-beta-D-glucoside GH1 6-phospho-beta-glucosidase 3.2.1.86 xylan GH10 xylan endotransglycosylase 2.4.2.- alpha-tomatine (glycoalkaloids) GH10 tomatinase 3.2.1.- arabinoxylan GH10 "[retaining] arabinoxylan-specific endo-beta-1,4-xylanase" 3.2.1.- xylan GH10 "endo-1,3-beta-xylanase" 3.2.1.32 "cellulose, xylan, beta-D-1,4-glucan" GH10 "endo-beta-1,4-glucanase" 3.2.1.4 xylan GH10 "endo-1,4-beta-xylanase" 3.2.1.8 sucrose GH100 alkaline and neutral invertase 3.2.1.26 mucin GH101 endo-alpha-N-acetylgalactosaminidase 3.2.1.97 peptidoglycan GH102 peptidoglycan lytic transglycosylase 3.2.1.- peptidoglycan GH103 peptidoglycan lytic transglycosylase 3.2.1.- peptidoglycan GH104 peptidoglycan lytic transglycosylase 3.2.1.- ulvan GH105 "d-4,5-unsaturated beta-glucuronyl hydrolase" 3.2.1.- pectin GH105 "d-4,5-unsaturated alpha-galacturonidase" 3.2.1.- pectin (rhamnogalacturonan I) GH105 unsaturated rhamnogalacturonyl hydrolase 3.2.1.172 pectin (rhamnogalacturonan I) GH106 rhamnogalacturonan alpha-L-rhamnohydrolase 3.2.1.174 pectin (rhamnogalacturonan II) GH106 alpha-L-rhamnosidase 3.2.1.40 fucoidan (brown algae) GH107 "endo-alpha-1,4-L-fucanase" 3.2.1.212 peptidoglycan GH108 N-acetylmuramidase 3.2.1.17 mucin-type O-glycans GH109 alpha-N-acetylgalactosaminidase 3.2.1.49 mucin-type O-glycans GH109 beta-N-acetylhexosaminidase 3.2.1.52 xylan GH11 "exo-1,4-beta-xylosidase" 3.2.1.- xylan GH11 "endo-beta-1,4-xylanase" 3.2.1.8 "blood group B substances, host glycans" GH110 "alpha-1,3-galactosidase" 3.2.1.- "blood group B substances, host glycans" GH110 alpha-galactosidase 3.2.1.22 "keratan, host glycans" GH111 keratan sulfate hydrolase (endo-beta-N-acetylglucosaminidase) 3.2.1.- "human milk oligosaccharides, host glycans" GH112 lacto-N-biose phosphorylase or galacto-N-biose phosphorylase 2.4.1.211 "human milk oligosaccharides, host glycans" GH112 "D-galactosyl-beta-1,4-L-rhamnose phosphorylase" 2.4.1.247 beta-mannan GH113 beta-mannanase 3.2.1.78 galactosaminogalactan (fungal exopolysaccharide) GH114 "endo-alpha-1,4-polygalactosaminidase" 3.2.1.109 arabinogalactan GH115 alpha-(4-O-methyl)-glucuronidase 3.2.1.- glucuronoxylan GH115 "xylan alpha-1,2-glucuronidase" 3.2.1.131 "human bile acid, archaea exo-polysaccharide (EPS)" GH116 beta-glucosidase 3.2.1.21 archaea exo-polysaccharide (EPS) GH116 beta-xylosidase 3.2.1.37 lipid glucosylceramide (host cell surface) GH116 acid beta-glucosidase/beta-glucosylceramidase 3.2.1.45 archaea exo-polysaccharide (EPS) GH116 beta-N-acetylglucosaminidase 3.2.1.52 neoagarose (marine algae) GH117 beta-D-galactofuranosidase 3.2.1.146 neoagarose (marine algae) GH117 alpha-neoagaro-oligosaccharide hydrolase 3.2.1.159 agarose (marine algae) GH118 beta-agarase 3.2.1.81 starch GH119 alpha-amylase 3.2.1.1 xyloglucan GH12 xyloglucan endotransglycosylase 2.4.1.207 xyloglucan GH12 xyloglucan hydrolase 3.2.1.151 "cellulose, beta-D-glucan" GH12 endoglucanase 3.2.1.4 mixed-linkage glucan GH12 "beta-1,3-1,4-glucanase" 3.2.1.73 xylan GH120 beta-xylosidase 3.2.1.37 hydroxyproline-rich glyoproteins (arabinan in extensin and lectin) GH121 beta-L-arabinobiosidase 3.2.1.- starch GH122 alpha-glucosidase 3.2.1.20 glycosphingolipid (host glycan) GH123 glycosphingolipid beta-N-acetylgalactosaminidase 3.2.1.- glycosphingolipid (host glycan) GH123 beta-N-acetylgalactosaminidase 3.2.1.53 cellulose GH124 endoglucanase 3.2.1.4 "alpha-mannan, plant N-glycan" GH125 "exo-alpha-1,6-mannosidase" 3.2.1.- "starch, glycogen, and malto-oligosaccharides" GH126 alpha-amylase 3.2.1.- pectin (rhamnogalacturonan II) GH127 3-C-carboxy-5-deoxy-L-xylose (aceric acid) hydrolase 3.2.1.- carrageenan (marine algae) GH127 "alpha-1,3-(3,6)-anhydro-D-galactosidase" 3.2.1.- arabinogalactan proteins GH127 beta-L-arabinofuranosidase 3.2.1.185 "beta-1,3-glucan (bacteria, fungi, plant, algae)" GH128 "beta-1,3-glucosidase" 3.2.1.- "beta-1,3-glucan (bacteria, fungi, plant, algae)" GH128 "beta-1,3-glucanase" 3.2.1.39 carrageenan (marine algae) GH129 "alpha-1,3-(3,6)-anhydro-D-galactosidase" 3.2.1.- mucin-type O-glycans GH129 alpha-N-acetylgalactosaminidase 3.2.1.49 "starch, glycogen, and malto-oligosaccharides" GH13 oligosaccharide alpha-4-glucosyltransferase 2.4.1.161 "starch, glycogen, and malto-oligosaccharides" GH13 branching enzyme 2.4.1.18 "cyclodextrin (¦Á-1,4 glycosidic glucan from starch degradation)" GH13 cyclomaltodextrin glucanotransferase 2.4.1.19 glycogen GH13 4-alpha-glucanotransferase 2.4.1.25 sucrose GH13 [retaining] sucrose 6(F)-phosphate phosphorylase 2.4.1.329 glucosylglycerate GH13 Glucosylglycerate phosphorylase 2.4.1.352 glucosylglycerol GH13 [retaining] glucosylglycerol phosphorylase 2.4.1.359 Sucrose GH13 amylosucrase 2.4.1.4 Sucrose GH13 sucrose phosphorylase 2.4.1.7 "starch, glycogen, and malto-oligosaccharides" GH13 "alpha-1,4-glucan: phosphate alpha-maltosyltransferase" 2.4.99.16 starch GH13 maltopentaose-forming alpha-amylase 3.2.1.- "starch, glycogen, and malto-oligosaccharides" GH13 alpha-amylase 3.2.1.1 "starch, glycogen, and malto-oligosaccharides" GH13 [retaining] alpha-amylase 3.2.1.1 amylopectin (starch) GH13 oligo-alpha-glucosidase 3.2.1.10 starch GH13 maltotriose-forming alpha-amylase 3.2.1.116 starch GH13 maltogenic amylase 3.2.1.133 pullulan (starch degradation by fungi) GH13 neopullulanase 3.2.1.135 starch GH13 malto-oligosyltrehalose trehalohydrolase 3.2.1.141 starch GH13 alpha-glucosidase 3.2.1.20 maltooligosaccharides GH13 "amylo-alpha-1,6-glucosidase" 3.2.1.33 pullulan (starch degradation by fungi) GH13 pullulanase 3.2.1.41 sucrose GH13 [retaining] sucrose alpha-glucosidase 3.2.1.48 cyclomaltodextrins GH13 cyclomaltodextrinase 3.2.1.54 starch GH13 maltotetraose-forming alpha-amylase 3.2.1.60 "starch, glycogen, and malto-oligosaccharides" GH13 isoamylase 3.2.1.68 "starch, glycogen, and ¦Á-1,6 glucan" GH13 glucodextranase 3.2.1.70 trehalose GH13 trehalose-6-phosphate hydrolase 3.2.1.93 "starch, glycogen, and malto-oligosaccharides" GH13 maltohexaose-forming alpha-amylase 3.2.1.98 sucrose GH13 isomaltulose synthase 5.4.99.11 starch GH13 malto-oligosyltrehalose synthase 5.4.99.15 maltose GH13 trehalose synthase 5.4.99.16 sucrose 6(F)-phosphate GH13 amino acid transporter - mannooligosaccharides GH130 "beta-1,2-oligomannan phosphorylase" 2.4.1.- beta-mannan GH130 "beta-1,2-mannobiose phosphorylase" 2.4.1.- beta-mannan GH130 "beta-1,4-mannosylglucose phosphorylase" 2.4.1.281 beta-mannan GH130 "beta-1,4-mannooligosaccharide phosphorylase" 2.4.1.319 beta-mannan GH130 "¦Â-1,2-oligomannan phosphorylase" 2.4.1.340 beta-mannan GH130 "¦Â-1,2-mannobiose phosphorylase" 2.4.1.339 beta-mannan GH130 "beta-1,4-mannosyl-N-acetyl-glucosamine phosphorylase" 2.4.1.320 beta-mannan GH130 "beta-1,2-mannosidase" 3.2.1.- "beta-glucans, including laminarin, curdlan, pachyman, lichenan, pustulan, and cellulosic derivatives" GH131 "broad specificity exo-beta-1,3/1,6-glucanase with endo-beta-1,4-glucanase activity" 3.2.1.- "beta-1,3-glucan (fungi)" GH132 "beta-1,3-glucosidase" 3.2.1.- glycogen GH133 "amylo-alpha-1,6-glucosidase" 3.2.1.33 beta-mannan GH134 "endo-beta-1,4-mannanase" 3.2.1.78 exopolysaccharide galactosaminogalactan (fungal GAG) GH135 "alpha-1,4-galactosaminogalactan hydrolase" 3.2.1.- human milk oligosaccharides GH136 Lacto-N-biosidase (Lewis antigen a/b specificity) 3.2.1.- human milk oligosaccharides GH136 lacto-N-biosidase 3.2.1.140 pectin (rhamnogalacturonan II) GH137 beta-L-arabinofuranosidase 3.2.1.185 pectin (rhamnogalacturonan II) GH138 "rhamnogalacturonan alpha-1,2-galacturonohydrolase" 3.2.1.173 pectin (rhamnogalacturonan II) GH139 alpha-2-O-Me-L-fucosidase 3.2.1.- "starch, glycogen and related polysaccharides and oligosaccharides" GH14 beta-amylase 3.2.1.2 pectin (rhamnogalacturonan II) GH140 "beta-1,2-apiosidase" 3.2.1.- pectin (rhamnogalacturonan II) GH141 alpha-L-fucosidase 3.2.1.51 xylan GH141 xylanase 3.2.1.8 pectin (rhamnogalacturonan II) GH142 beta-L-arabinofuranosidase 3.2.1.185 pectin (rhamnogalacturonan II) GH143 2-keto-3-deoxy-D-lyxo-heptulosaric acid hydrolase 3.2.1.- "beta-1,2-glucan (bacteria)" GH144 "beta-1,2-glucooligosaccharide sophorohydrolase" 3.2.1.214 "beta-1,2-glucan (bacteria)" GH144 "endo-beta-1,2-glucanase" 3.2.1.71 arabinan GH146 beta-L-arabinofuranosidase 3.2.1.185 galactan GH147 beta-galactosidase 3.2.1.89 galactan GH147 beta-galactosidase 3.2.1.23 glucomannan GH148 "beta-1,3-glucanase" 3.2.1.4 beta-glucan and lichenin GH148 "beta-1,3-glucanase" 3.2.1.- "beta-1,3-glucan" GH149 "beta-1,3-glucan phosphorylase" 2.4.1.97 starch GH15 dextran dextrinase 2.4.1.2 trehalose GH15 "alpha,alpha-trehalase" 3.2.1.28 starch GH15 glucoamylase 3.2.1.3 starch GH15 glucodextranase 3.2.1.70 carrageenan GH150 Iota-carrageenase 3.2.1.162 fucosylated human milk oligosaccharides GH151 alpha-L-fucosidase 3.2.1.51 "beta-1,3-glucan (fungal lentinan)" GH152 "beta-1,3-glucanase" 3.2.1.39 "deacetylated poly-¦Â(1,6)-N-acetyl-D-glucosamine (bacterial PNAG for biofilm)" GH153 "poly-beta-1,6-D-glucosamine hydrolase" 3.2.1.- arabinogalactan proteins GH154 "beta-1,6-D-glucuronidase" 3.2.1.- arabinogalactan proteins GH154 beta-glucuronidase 3.2.1.31 "sialic acid (O-glycan, N-glycan, mucin, host glycan)" GH156 exo-alpha-sialidase 3.2.1.18 beta-glucans (bacteria curdlan) GH157 "endo-beta-1,3-glucanase / laminarinase" 3.2.1.39 "beta-glucans (yeast, seaweed, and plant)" GH158 "endo-beta-1,3-glucanase" 3.2.1.39 beta-galactoside GH159 beta-D-galactofuranosidase 3.2.1.146 chitin GH16 "chitin beta-1,6-glucanosyltransferase" 2.4.1.- "beta-1,3-glucan" GH16 beta-transglycosidase 2.4.1.- xyloglucan (plant) GH16 xyloglucan:xyloglucosyltransferase 2.4.1.207 mucin-type O-glycans GH16 "endo-beta-1,4-galactosidase" 3.2.1.- exopolysaccharides (bacteria) GH16 beta-glycosidase 3.2.1.- carrageenan GH16 beta-carrageenase 3.2.1.- keratan sulfate (host glycan) GH16 "keratan-sulfate endo-1,4-beta-galactosidase" 3.2.1.103 xyloglucan GH16 xyloglucanase 3.2.1.151 porphyran (red algal beta-galactose-sulfate) GH16 [retaining] beta-porphyranase 3.2.1.178 arabinogalactan proteins GH16 "endo-beta-1,3-galactanase" 3.2.1.181 hyaluronate (glycosaminoglycan of host glycan) GH16 hyaluronidase 3.2.1.35 "beta-1,3-glucan (fungi, algae, plant)" GH16 "endo-1,3-beta-glucanase / laminarinase" 3.2.1.39 "beta-1,3-1,4-glucan (laminarin, lichenin and cereal D-glucans)" GH16 "endo-1,3(4)-beta-glucanase" 3.2.1.6 "beta-1,3-1,4-glucan (laminarin, lichenin and cereal D-glucans)" GH16 licheninase 3.2.1.73 agarose GH16 beta-agarase 3.2.1.81 carrageenan GH16 kappa-carrageenase 3.2.1.83 exopolysaccharides (bacteria) GH160 "endo-beta-1,4-galactosidase" 3.2.1.- "beta-1,3-glucan (fungi, algae, plant)" GH161 "beta-1,3-glucan phosphorylase" 2.4.1.97 "beta-1,2-glucan (bacteria)" GH162 "endo-beta-1,2-glucanase" 3.2.1.71 N-glycan (host glycan) GH163 "endo-beta-N-acetylglucosaminidase cleaving GlcNAc-beta-1,2-Man" 3.2.1.- beta-D-mannoside GH164 beta-mannosidase 3.2.1.25 beta-D-galactoside GH165 beta-galactosidase 3.2.1.23 exopolysaccharide galactosaminogalactan (fungal GAG) GH166 "alpha-1,4-galactosaminogalactan hydrolase" 3.2.1.- carrageenan GH167 beta-carrageenase 3.2.1.- Sulfated fucans (algae) GH168 "endo-alpha-(1,3)-L-fucanase" 3.2.1.211 capsular polysaccharide (bacteria) GH169 "beta-1,4-D-glucuronidase" 3.2.1.- capsular polysaccharide (bacteria) GH169 beta-glucuronidase 3.2.1.31 "beta-1,3-glucan (fungi, algae, plant)" GH17 "beta-1,3-glucanosyltransglycosylase" 2.4.1.- "beta-1,3-glucan (fungi)" GH17 "beta-1,3-glucosidase" 3.2.1.- abscisic acid (plant) GH17 ABA-specific beta-glucosidase 3.2.1.175 "beta-1,3-glucan (algae, plant)" GH17 "glucan endo-1,3-beta-glucosidase" 3.2.1.39 "beta-1,3-1,4-glucan (laminarin, lichenin and cereal D-glucans)" GH17 licheninase 3.2.1.73 peptidoglycan GH170 6-phospho-N-acetylmuramidase 3.2.1.- peptidoglycan GH171 peptidoglycan beta-N-acetylmuramidase 3.2.1.92 fructooligosaccharides GH172 difructose-anhydride synthase 3.2.1.134 beta-galactoside (pectin) GH173 ¦Â-galactosidase (EC 3.2.1.23) 3.2.1.23 peptidoglycan GH18 peptidoglycan hydrolase with endo-beta-N-acetylglucosaminidase specificity 3.2.1.- chitooligosaccharides (symbiotic nitrogen-fixing bacteria) GH18 Nod factor hydrolase 3.2.1.- chitin GH18 chitinase 3.2.1.14 peptidoglycan GH18 lysozyme 3.2.1.17 N-glycan (host glycan) GH18 endo-beta-N-acetylglucosaminidase 3.2.1.96 chitin GH19 chitinase 3.2.1.14 chitin GH19 chitinase 3.2.1.- peptidoglycan GH19 lysozyme 3.2.1.17 pectin (rhamnogalacturonan II) GH2 alpha-L-arabinopyranosidase 3.2.1.- pectin (rhamnogalacturonan II) GH2 beta-galacturonidase 3.2.1.- galactomannan (fungi) GH2 beta-D-galactofuranosidase 3.2.1.146 N-glycan (plant) GH2 mannosylglycoprotein endo-beta-mannosidase 3.2.1.152 chitosan or chitosan oligosaccharides (nonacetylated chitin) GH2 exo-beta-glucosaminidase 3.2.1.165 beta-D-glucoside GH2 beta-glucosidase 3.2.1.21 beta-D-galactoside GH2 beta-galactosidase 3.2.1.23 beta-D-mannoside GH2 beta-mannosidase 3.2.1.25 beta-D-glucuronoside GH2 beta-glucuronidase 3.2.1.31 beta-D-xyloside GH2 beta-xylosidase 3.2.1.37 arabinan GH2 alpha-L-arabinofuranosidase 3.2.1.55 capsular polysaccharide (bacteria) GH20 "beta-1,6-N-acetylglucosaminidase" 3.2.1.- mucin GH20 beta-6-SO3-N-acetylglucosaminidase 3.2.1.- lacto-N-tetraose (human milk oligosaccharides) GH20 lacto-N-biosidase 3.2.1.140 "N-glycan (host glycan, human milk oligosaccharides, chitin)" GH20 beta-hexosaminidase 3.2.1.52 peptidoglycan GH22 lysozyme type C 3.2.1.17 peptidoglycan GH22 lysozyme type i 3.2.1.17 chitin GH23 chitinase 3.2.1.14 peptidoglycan GH23 lysozyme type G 3.2.1.17 peptidoglycan GH23 peptidoglycan lyase ( also known in the literature as peptidoglycan lytic transglycosylase) 4.2.2.n1 peptidoglycan GH24 lysozyme 3.2.1.17 peptidoglycan GH25 lysozyme 3.2.1.17 beta-mannan GH26 mannobiose-producing exo-beta-mannanase 3.2.1.- beta-mannan (plant) GH26 "exo-beta-1,4-mannobiohydrolase" 3.2.1.100 "beta(1,3)-xylan (algae)" GH26 "beta-1,3-xylanase" 3.2.1.32 beta-D-glucan GH26 "lichenase / endo-beta-1,3-1,4-glucanase" 3.2.1.73 beta-mannan (plant) GH26 beta-mannanase 3.2.1.78 raffinose family oligosaccharide (plant) GH27 galactan:galactan galactosyltransferase 2.4.1.- "alpha-D-galactoside, galactose oligosaccharides (plant), galactomannans (plant) and galactolipid (animal)" GH27 alpha-galactosidase 3.2.1.22 "human blood group A, mucin, host glycan" GH27 alpha-N-acetylgalactosaminidase 3.2.1.49 arabinogalactan GH27 beta-L-arabinopyranosidase 3.2.1.88 dextran and isomalto-oligosaccharides (bacteria) GH27 isomalto-dextranase 3.2.1.94 xylogalacturonan (pectin) GH28 xylogalacturonan hydrolase 3.2.1.- galacturonan (pectin) GH28 polygalacturonase 3.2.1.15 rhamnogalacturonan (pectin) GH28 rhamnogalacturonase 3.2.1.171 pectin (rhamnogalacturonan I) GH28 "rhamnogalacturonan alpha-1,2-galacturonohydrolase" 3.2.1.173 galacturonan (pectin) GH28 exo-polygalacturonase 3.2.1.67 galacturonan (pectin) GH28 exo-polygalacturonosidase 3.2.1.82 "human milk oligosaccharides, mucin, host glycan" GH29 "alpha-1,3/1,4-L-fucosidase" 3.2.1.111 "human milk oligosaccharides, mucin, host glycan" GH29 alpha-L-fucosidase 3.2.1.51 "human milk oligosaccharides, mucin, host glycan" GH29 "alpha-1,2-L-fucosidase" 3.2.1.63 peptidoglycan GH3 beta-N-acetylglucosaminide phosphorylases 2.4.1.- "beta-1,3-1,4-glucan (laminarin, lichenin and cereal D-glucans)" GH3 "exo-1,3-1,4-glucanase" 3.2.1.- "beta-1,2-glucan (bacteria)" GH3 "beta-1,2-glucosidase" 3.2.1.- "beta-1,3-glucan (laminarin, lichenin and cereal D-glucans)" GH3 "beta-1,3-glucosidase" 3.2.1.- xyloglucan (plant) GH3 isoprimeverose-producing oligoxyloglucan hydrolase 3.2.1.120 coniferin (glucoside of coniferyl alcohol) GH3 coniferin beta-glucosidase 3.2.1.126 xyloglucan (plant) GH3 "xyloglucan-specific exo-beta-1,4-glucanase / exo-xyloglucanase" 3.2.1.155 protodioscin (plant steroidal saponin) GH3 protodioscin 26-O-¦Â-D-glucosidase 3.2.1.186 beta-glucan GH3 beta-glucosidase 3.2.1.21 xylan GH3 "xylan 1,4-beta-xylosidase" 3.2.1.37 glycosphingolipid (host glycan) GH3 beta-glucosylceramidase 3.2.1.45 "chitin, peptidoglycan" GH3 beta-N-acetylhexosaminidase 3.2.1.52 "arabinan, arabinoxylan" GH3 alpha-L-arabinofuranosidase 3.2.1.55 "beta-1,3-glucan (laminarin, lichenin and cereal D-glucans)" GH3 "lichenase / endo-beta-1,3-1,4-glucanase" 3.2.1.73 "cellodextrin (beta-1,3-glucan)" GH3 "glucan 1,4-beta-glucosidase" 3.2.1.74 xylan GH30 [reducing end] beta-xylosidase 3.2.1.- xylan GH30 "glucuronoarabinoxylan endo-beta-1,4-xylanase" 3.2.1.136 arabinogalactan proteins GH30 "endo-beta-1,6-galactanase" 3.2.1.164 beta-glucan GH30 beta-glucosidase 3.2.1.21 beta-D-glucuronoside GH30 beta-glucuronidase 3.2.1.31 xylan GH30 beta-xylosidase 3.2.1.37 beta-D-fucoside GH30 beta-fucosidase 3.2.1.38 "glucosylsphingosine, glucosylceramide (host glycans)" GH30 glucosylceramidase 3.2.1.45 "beta-1,6-glucan (fungal and algal cell wall)" GH30 "beta-1,6-glucanase" 3.2.1.75 xylan GH30 "endo-beta-1,4-xylanase" 3.2.1.8 glycogen and starch GH31 "oligosaccharide alpha-1,4-glucosyltransferase" 2.4.1.161 xyloglucan (plant) GH31 alpha-xylosidase 3.2.1.177 sulfoquinovoside (plant sulfolipid) GH31 sulfoquinovosidase 3.2.1.199 starch GH31 alpha-glucosidase 3.2.1.20 alpha-D-galactoside GH31 alpha-galactosidase 3.2.1.22 alpha-D-mannoside GH31 alpha-mannosidase 3.2.1.24 sucrose GH31 sucrase-isomaltase 3.2.1.48 "human blood group A, mucin, host glycan" GH31 alpha-N-acetylgalactosaminidase 3.2.1.49 glycogen and starch GH31 "alpha-1,3-glucosidase" 3.2.1.84 glycogen and starch GH31 alpha-glucan lyase 4.2.2.13 levan (fructan) GH32 levan fructosyltransferase 2.4.1.- graminan- and levan-type fructans GH32 [retaining] sucrose:sucrose 6-fructosyltransferase (6-SST) 2.4.1.- "fructan(inulin, levan and sucrose)" GH32 cycloinulo-oligosaccharide fructanotransferase 2.4.1.- "fructan(inulin, levan and sucrose)" GH32 sucrose:fructan 6-fructosyltransferase 2.4.1.10 "fructan(inulin, levan and sucrose)" GH32 fructan:fructan 1-fructosyltransferase 2.4.1.100 "fructan(inulin, levan and sucrose)" GH32 fructan:fructan 6G-fructosyltransferase 2.4.1.243 "fructan(inulin, levan and sucrose)" GH32 sucrose:sucrose 1-fructosyltransferase 2.4.1.99 fructan GH32 "fructan beta-(2,1)-fructosidase/1-exohydrolase" 3.2.1.153 fructan GH32 "fructan beta-(2,6)-fructosidase/6-exohydrolase" 3.2.1.154 "fructan(inulin, levan and sucrose)" GH32 invertase 3.2.1.26 "fructan(inulin, levan and sucrose)" GH32 "beta-2,6-fructan 6-levanbiohydrolase" 3.2.1.64 levan (fructan) GH32 endo-levanase 3.2.1.65 inulin GH32 endo-inulinase 3.2.1.7 "fructan(inulin, levan and sucrose)" GH32 exo-inulinase 3.2.1.80 sialic acid GH33 trans-sialidase 2.4.1.- "pectin (rhamnogalacturonan II), lipopolysaccharides (bacteria)" GH33 Kdo hydrolase 3.2.1.- "sialic acid (O-glycan, N-glycan, mucin, host glycan)" GH33 sialidase or neuraminidase 3.2.1.18 "sialic acid (O-glycan, N-glycan, mucin, host glycan)" GH33 anhydrosialidase 4.2.2.15 "sialic acid (O-glycan, N-glycan, mucin, host glycan)" GH34 sialidase or neuraminidase 3.2.1.18 galactan and arabinogalactan GH35 "beta-1,3-galactosidase" 3.2.1.- "chitosan, chitin" GH35 exo-beta-glucosaminidase 3.2.1.165 beta-galactoside (pectin) GH35 beta-galactosidase 3.2.1.23 raffinose/stachyose oligosaccharides (plant seeds) GH36 stachyose synthase 2.4.1.67 raffinose oligosaccharides GH36 raffinose synthase 2.4.1.82 "alpha-D-galactoside (galactose oligosaccharides, galactomannans and galactolipid)" GH36 alpha-galactosidase 3.2.1.22 "acetylgalactosamine (human blood group A and b, mucin glycoproteins)" GH36 alpha-N-acetylgalactosaminidase 3.2.1.49 alpha-trehalose GH37 "alpha,alpha-trehalase" 3.2.1.28 alpha-mannan (fungi) GH38 "mannosyl-oligosaccharide alpha-1,3-mannosidase" 3.2.1.- "N-glycans, O-glycans, alpha-mannan (fungi)" GH38 "mannosyl-oligosaccharide alpha-1,2-mannosidase" 3.2.1.113 N-glycans GH38 "mannosyl-oligosaccharide alpha-1,3-1,6-mannosidase" 3.2.1.114 "N-glycans, O-glycans, alpha-mannan (fungi)" GH38 alpha-mannosidase 3.2.1.24 "beta-glucoside (exopolysaccharide, cellubiose)" GH39 beta-glucosidase 3.2.1.21 beta-D-galactoside GH39 beta-galactosidase 3.2.1.23 xylan GH39 beta-xylosidase 3.2.1.37 "arabinoxylan (galacto-(¦Á-1,2)-arabinosidase)" GH39 alpha-L-arabinofuranosidase 3.2.1.55 beta-glucoside (cellubiose) GH39 "exo-beta-1,4-glucanase / cellodextrinase" 3.2.1.74 glycosaminoglycans heparan sulfate and dermatan sulfate (host glycan) GH39 alpha-L-iduronidase 3.2.1.76 "isomaltulose (palatinose, from honey and sugar cane)" GH4 palatinase 3.2.1.- sucrose and its isomeric disaccharides GH4 maltose-6-phosphate glucosidase 3.2.1.122 alpha-glucuronide in glucuronoxylan GH4 alpha-glucuronidase 3.2.1.139 maltose and other small maltooligosaccharides GH4 alpha-glucosidase 3.2.1.20 alpha-D-galactoside (raffinose family of oligosaccharides) GH4 alpha-galactosidase 3.2.1.22 galacturonides (polygalacturonan of pectin) GH4 alpha-galacturonase 3.2.1.67 "beta-glucoside (sinigrin, cellubiose)" GH4 6-phospho-beta-glucosidase 3.2.1.86 "paeonolide, ginsenoside, arabinoxylan, and arabinan" GH42 alpha-L-arabinopyranosidase 3.2.1.- "beta-1,6/1,3-galactoside (arabinogalactan)" GH42 beta-galactosidase 3.2.1.23 "arabinan, arabinoxylan" GH43 "alpha-1,2-L-arabinofuranosidase" 3.2.1.- "arabinan, arabinoxylan" GH43 "exo-alpha-1,5-L-arabinofuranosidase" 3.2.1.- arabinan GH43 "[inverting] exo-alpha-1,5-L-arabinanase" 3.2.1.- "beta-1,3-xylan (algae)" GH43 "beta-1,3-xylosidase" 3.2.1.- "beta-1,3-D-galactan, arabinogalactan" GH43 "exo-beta-1,3-galactanase" 3.2.1.145 beta-D-galactofuranoside GH43 beta-D-galactofuranosidase 3.2.1.146 xylan GH43 beta-xylosidase 3.2.1.37 arabinoxylan GH43 alpha-L-arabinofuranosidase 3.2.1.55 xylan GH43 xylanase 3.2.1.8 arabinan GH43 "[inverting] endo-alpha-1,5-L-arabinanase" 3.2.1.99 xyloglucan GH44 xyloglucanase 3.2.1.151 "cellulose, lichenin and cereal beta-D-glucan" GH44 endoglucanase 3.2.1.4 xyloglucan GH45 "xyloglucan-specific endo-beta-1,4-glucanase / endo-xyloglucanase" 3.2.1.151 "cellulose, lichenin and cereal beta-D-glucan" GH45 endoglucanase 3.2.1.4 "mannans, galactomannans and glucomannan" GH45 "endo-beta-1,4-mannanase" 3.2.1.78 chitosan GH46 chitosanase 3.2.1.132 protein-linked N-glycan (host glycan) GH47 alpha-mannosidase 3.2.1.113 chitin and chitodextrin GH48 chitinase 3.2.1.14 cellulose GH48 reducing end-acting cellobiohydrolase 3.2.1.176 cellulose GH48 "endo-beta-1,4-glucanase" 3.2.1.4 sulfated arabinan GH49 "sulfated arabinan endo-1,4-beta-L-arabinanase" 3.2.1.- dextran (branched alpha-glucan) GH49 dextranase 3.2.1.11 pullulan (starch degradation by fungi) GH49 isopullulanase 3.2.1.57 dextran (branched alpha-glucan) GH49 "dextran 1,6-alpha-isomaltotriosidase" 3.2.1.95 beta-mannan (plant) GH5 mannan transglycosylase 2.4.1.- beta-mannan GH5 "beta-1,3-mannanase" 3.2.1.- arabinoxylans GH5 "arabinoxylan-specific endo-beta-1,4-xylanase" 3.2.1.- beta-glycoside GH5 beta-glycosidase 3.2.1.- rutin (polyphenol) GH5 "beta-rutinosidase /alpha-L-rhamnose-(1,6)-beta-D-glucosidase" 3.2.1.- glucomannan GH5 "glucomannan-specific endo-beta-1,4-glucanase" 3.2.1.- sterylglucoside (fungi) GH5 steryl beta-glucosidase 3.2.1.104 glycosphingolipids GH5 endoglycoceramidase 3.2.1.123 chitosan GH5 chitosanase 3.2.1.132 arabinogalactan (bacteria) GH5 beta-D-galactofuranosidase 3.2.1.146 beta-diglycoside GH5 beta-primeverosidase 3.2.1.149 xyloglucan GH5 "xyloglucan-specific endo-beta-1,4-glucanase" 3.2.1.151 arabinogalactan GH5 "endo-beta-1,6-galactanase" 3.2.1.164 naringenin (flavonoid) and tea aroma GH5 beta-glucosidase 3.2.1.21 "N-glycans, beta-mannan" GH5 beta-mannosidase 3.2.1.25 "laminarin (algae), pustulan (fungi)" GH5 "endo-beta-1,3-glucanase / laminarinase" 3.2.1.39 "cellulose, beta-D-glucan" GH5 "endo-beta-1,4-glucanase / cellulase" 3.2.1.4 fungus-specific glucosylceramide (glycolipid) GH5 beta-glucosylceramidase 3.2.1.45 "glycosphingolipid, galactolipids" GH5 beta-galactosylceramidase 3.2.1.46 chitin GH5 beta-N-acetylhexosaminidase 3.2.1.52 arabinan GH5 alpha-L-arabinofuranosidase 3.2.1.55 "beta-1,3-glucans (laminarin)" GH5 "glucan beta-1,3-glucosidase" 3.2.1.58 "beta-D-glucan(contains both (1->3)- and (1->4)-bonds),lichenin and cereal beta-D-glucan" GH5 "lichenase / endo-beta-1,3-1,4-glucanase" 3.2.1.73 cellulose and similar substrates GH5 "exo-beta-1,4-glucanase / cellodextrinase" 3.2.1.74 "laminarin (algae), pustulan (fungi)" GH5 "glucan endo-1,6-beta-glucosidase" 3.2.1.75 "mannans, galactomannans and glucomannan" GH5 "mannan endo-beta-1,4-mannosidase" 3.2.1.78 xylan GH5 "endo-beta-1,4-xylanase" 3.2.1.8 cellulose GH5 "cellulose beta-1,4-cellobiosidase" 3.2.1.91 "porphyran, agarose" GH50 beta-agarase 3.2.1.81 arabinan GH51 beta-xylosidase 3.2.1.37 "cellulose, beta-D-glucan" GH51 endoglucanase 3.2.1.4 "arabinan, arabinoxylan" GH51 alpha-L-arabinofuranosidase 3.2.1.55 xylan GH51 "endo-beta-1,4-xylanase" 3.2.1.8 xylan GH52 beta-xylosidase 3.2.1.37 arabinogalactan GH53 "endo-beta-1,4-galactanase" 3.2.1.89 "arabinan, arabinoxylan" GH54 beta-xylosidase 3.2.1.37 "arabinan, arabinoxylan" GH54 alpha-L-arabinofuranosidase 3.2.1.55 laminarin (algae) GH55 laminarin-degrading enzyme 3.2.1.- "laminarin (algae), pustulan (fungi)" GH55 "endo-beta-1,3-glucanase" 3.2.1.39 "laminarin (algae), pustulan (fungi)" GH55 "exo-beta-1,3-glucanase" 3.2.1.58 "glycosaminoglycan, hyaluronan, chondroitin sulfate, host glycan" GH56 chondroitin hydrolase 3.2.1.- "glycosaminoglycan, hyaluronan, chondroitin sulfate, host glycan" GH56 hyaluronidase 3.2.1.35 "beta-1,4-glucan, glycogen" GH57 branching enzyme 2.4.1.18 "starch, glycogen, and malto-oligosaccharides" GH57 4-alpha-glucanotransferase 2.4.1.25 "starch, glycogen and related polysaccharides and oligosaccharides(containing three or more (1->4)-alpha-linked D-glucose units)" GH57 alpha-amylase 3.2.1.1 "alpha-D-galactoside, melibiose and raffinose" GH57 alpha-galactosidase 3.2.1.22 "pullulan, maltodextrins and cyclodextrin" GH57 amylopullulanase 3.2.1.41 "pullulan, maltodextrins and cyclodextrin" GH57 cyclomaltodextrinase 3.2.1.54 sialic acid GH58 endo-N-acetylneuraminidase or endo-sialidase 3.2.1.129 beta-D-galactoside GH59 beta-galactosidase 3.2.1.23 "galactosylceramide, sphingolipids, galactolipids" GH59 galactocerebrosidase 3.2.1.46 cellulose GH6 endoglucanase 3.2.1.4 cellulose GH6 "lichenase / endo-beta-1,3-1,4-glucanase" 3.2.1.73 cellulose GH6 cellobiohydrolase 3.2.1.91 "arabinoxylans, arabinogalactans, arabinan" GH62 alpha-L-arabinofuranosidase 3.2.1.55 N-glycans GH63 processing alpha-glucosidase 3.2.1.106 mannosylglycerate GH63 mannosylglycerate alpha-mannosidase / mannosylglycerate hydrolase 3.2.1.170 "nigerose, trehalose, kojibiose, and maltooligosaccharide" GH63 alpha-glucosidase 3.2.1.20 glucosylglycerate GH63 glucosylglycerate hydrolase 3.2.1.208 "nigerose, trehalose, kojibiose, and maltooligosaccharide" GH63 "alpha-1,3-glucosidase" 3.2.1.84 "beta-1,3-glucan (fungal cell walls)" GH64 "beta-1,3-glucanase" 3.2.1.39 "kojibiose and alpha-1,2-oligoglucan" GH65 2-O-alpha-glucopyranosylglycerol: phosphate beta-glucosyltransferase 2.4.1.- "trehalose (¦Á1,1), kojibiose (¦Á1,2)" GH65 trehalose-6-phosphate phosphorylase 2.4.1.216 kojibiose GH65 kojibiose phosphorylase 2.4.1.230 "nigerose (¦Á1,3)" GH65 nigerose phosphorylase 2.4.1.279 "glucopyranosyl-¦Á-1,3-rhamnose (bacteria lipopolysaccharides or capsule polysaccharides)" GH65 3-O-alpha-glucopyranosyl-L-rhamnose phosphorylase 2.4.1.282 "1,3-¦Á-oligoglucan " GH65 "1,3-¦Á-oligoglucan phosphorylase" 2.4.1.334 trehalose GH65 trehalose phosphorylase 2.4.1.64 "maltose (¦Á1,4)" GH65 maltose phosphorylase 2.4.1.8 collagen GH65 "alpha-glucosyl-1,2-beta-galactosyl-L-hydroxylysine alpha-glucosidase" 3.2.1.107 trehalose GH65 "alpha,alpha-trehalase" 3.2.1.28 "dextran (¦Á1,6)" GH66 cycloisomaltooligosaccharide glucanotransferase 2.4.1.248 dextran GH66 dextranase 3.2.1.11 xylan side chain GH67 "xylan alpha-1,2-glucuronidase" 3.2.1.131 xylan side chain GH67 alpha-glucuronidase 3.2.1.139 "sucrose,Levan" GH68 levansucrase 2.4.1.10 fructan GH68 inulosucrase 2.4.1.9 "fructan, sucrose" GH68 beta-fructofuranosidase 3.2.1.26 chitosan GH7 chitosanase 3.2.1.132 cellulose and similar substrates GH7 reducing end-acting cellobiohydrolase 3.2.1.176 "cellulose, lichenin and cereal beta-D-glucan" GH7 "endo-beta-1,4-glucanase" 3.2.1.4 "beta-D-glucan, lichenin" GH7 "endo-beta-1,3-1,4-glucanase" 3.2.1.73 "beta-glucan, cellulose, laminarin, oat spelt xylan" GH70 reuteransucrase 2.4.1.- "starch,maltose, beta-glucan ,lichenan,laminarin, xylan" GH70 "alpha-4,6-glucanotransferase" 2.4.1.- glucan GH70 "alpha-1,2-branched dextransucrase" 2.4.1.- glucan GH70 "alpha-4,3-glucanotransferase" 2.4.1.- sucrose GH70 alternansucrase 2.4.1.140 sucrose GH70 dextransucrase 2.4.1.5 glucan GH71 "alpha-1,3-glucanase" 3.2.1.59 glucan GH72 "beta-1,3-glucanosyltransglycosylase" 2.4.1.- host glycan GH73 peptidoglycan hydrolase with endo-beta-N-acetylglucosaminidase specificity 3.2.1.- host glycan GH73 lysozyme 3.2.1.17 host glycan GH73 mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 3.2.1.96 hemicellulose GH74 oligoxyloglucan reducing end-specific cellobiohydrolase 3.2.1.150 Xyloglucan GH74 xyloglucanase 3.2.1.151 "cellulose, lichenin and cereal beta-D-glucan" GH74 endoglucanase 3.2.1.4 chitosan GH75 chitosanase 3.2.1.132 mannans GH76 "alpha-1,6-mannanase" 3.2.1.101 alpha-D-glucose GH76 alpha-glucosidase 3.2.1.20 "maltose, starch" GH77 amylomaltase or 4-alpha-glucanotransferase 2.4.1.25 pectin GH78 "L-Rhap-alpha-1,3-D-Apif -specific alpha-1,3-L-rhamnosidase" 3.2.1.- host glycan(pectin) GH78 rhamnogalacturonan alpha-L-rhamnohydrolase 3.2.1.174 host glycan GH78 alpha-L-rhamnosidase 3.2.1.40 host glycan GH79 beta-4-O-methyl-glucuronidase 3.2.1.- host glycan GH79 heparanase 3.2.1.166 host glycan GH79 baicalin beta-glucuronidase 3.2.1.167 host glycan GH79 beta-glucuronidase 3.2.1.31 host glycan(hyaluronate) GH79 hyaluronoglucuronidase 3.2.1.36 chitosan GH8 chitosanase 3.2.1.132 xylan GH8 reducing-end-xylose releasing exo-oligoxylanase 3.2.1.156 "beta-D-glucan(cellulose, lichenin and cereal D-glucans)" GH8 cellulase 3.2.1.4 "beta-D-glucan(laminarin, lichenin and cereal D-glucans)" GH8 "endo-beta-1,3(4)-glucanase / lichenase-laminarinase" 3.2.1.6 beta-D-glucan(lichenin and cereal beta-D-glucan) GH8 licheninase 3.2.1.73 xylan GH8 "endo-1,4-beta-xylanase" 3.2.1.8 chitosan GH80 chitosanase 3.2.1.132 "¦Â-1,3-glucan(laminarin, paramylon and pachyman)" GH81 "endo-beta-1,3-glucanase" 3.2.1.39 iota-carrageenans GH82 ¦É-carrageenase 3.2.1.157 host glycan GH83 neuraminidase 3.2.1.18 host glycan GH84 [protein]-3-O-(GlcNAc)-L-Ser/Thr beta-N-acetylglucosaminidase 3.2.1.169 host glycan GH84 hyaluronidase 3.2.1.35 host glycan GH84 N-acetyl beta-glucosaminidase 3.2.1.52 host glycan GH85 endo-beta-N-acetylglucosaminidase 3.2.1.96 porphyran GH86 beta-porphyranase 3.2.1.178 "porphyran, agarose" GH86 beta-agarase 3.2.1.81 nigeran(alpha-glucan in fungi) GH87 "alpha-1,3-glucanase" 3.2.1.59 "¦Á-1,3-glucan" GH87 mycodextranase 3.2.1.61 host glycan GH88 "d-4,5-unsaturated beta-glucuronyl hydrolase" 3.2.1.- host glycan GH88 unsaturated chondroitin disaccharide hydrolase 3.2.1.180 host glycan GH89 alpha-N-acetylglucosaminidase 3.2.1.50 xanthan GH9 "endo-beta-1,4-glucanase (xanthanase)" 3.2.1.- Xyloglucan GH9 "xyloglucan-specific endo-beta-1,4-glucanase / endo-xyloglucanase" 3.2.1.151 chitosan or chitosan oligosaccharides GH9 exo-beta-glucosaminidase 3.2.1.165 "cellulose, lichenin and cereal beta-D-glucan" GH9 endoglucanase 3.2.1.4 "beta-D-glucan(laminarin, lichenin and cereal D-glucans)" GH9 "endo-beta-1,3(4)-glucanase / lichenase-laminarinase" 3.2.1.6 "beta-D-glucan, lichenin" GH9 "lichenase / endo-beta-1,3-1,4-glucanase" 3.2.1.73 cellulose GH9 "exo-beta-1,4-glucanase / cellodextrinase" 3.2.1.74 cellulose and cellotetraose GH9 cellobiohydrolase 3.2.1.91 host glycan GH90 endorhamnosidase 3.2.1.- Inulin GH91 "difructofuranose 1,2':2,3' dianhydride hydrolase [DFA-IIIase]" 3.2.1.- inulin GH91 inulin lyase [DFA-I-forming] 4.2.2.17 inulin GH91 inulin lyase [DFA-III-forming] 4.2.2.18 host N-glycan GH92 "mannosyl-oligosaccharide alpha-1,3-mannosidase" 3.2.1.- host N-glycan GH92 "mannosyl-oligosaccharide alpha-1,6-mannosidase" 3.2.1.- host N-glycan GH92 "alpha-1,2-mannosidase" 3.2.1.- host N-glycan GH92 "alpha-1,3-mannosidase" 3.2.1.- host N-glycan GH92 "alpha-1,4-mannosidase" 3.2.1.- host N-glycan GH92 "mannosyl-1-phosphodiester alpha-1,P-mannosidase" 3.2.1.- host N-glycan GH92 "mannosyl-oligosaccharide alpha-1,2-mannosidase" 3.2.1.113 host N-glycan GH92 alpha-mannosidase 3.2.1.24 "arabinan(pectin),hemicellulose" GH93 "exo-alpha-L-1,5-arabinanase" 3.2.1.- chitobiose GH94 chitobiose phosphorylase 2.4.1.280 4-O-¦Â-D-glucosyl-D-galactose GH94 4-O-¦Â-D-glucosyl-D-galactose phosphorylase 2.4.1.- "1,2-¦Â-oligoglucan" GH94 "¦Â-1,2-oligoglucan phosphorylase" 2.4.1.333 Cellobiose GH94 cellobiose phosphorylase 2.4.1.20 laminarin GH94 laminaribiose phosphorylase 2.4.1.31 cellobionic acid GH94 cellobionic acid phosphorylase 2.4.1.321 cellodextrin GH94 cellodextrin phosphorylase 2.4.1.49 "plant pectic polysaccharide, xylan" GH95 alpha-L-galactosidase 3.2.1.- alpha-L-fucoside GH95 alpha-L-fucosidase 3.2.1.51 "alpha1,2-L-fucosidase sugar" GH95 "alpha-1,2-L-fucosidase" 3.2.1.63 agarose GH96 alpha-agarase 3.2.1.158 alpha-D-glucose residue GH97 alpha-glucosidase 3.2.1.20 "alpha-D-galactoside, alpha-D-fucoside" GH97 alpha-galactosidase 3.2.1.22 beta-D-glucose GH97 glucoamylase 3.2.1.3 "blood group A and B substances, host glycans" GH98 "blood-group endo-beta-1,4-galactosidase" 3.2.1.102 xylan GH98 "endo-beta-1,4-xylanase" 3.2.1.8 host N-glycan GH99 "glycoprotein endo-alpha-1,2-mannosidase" 3.2.1.130 alpha-mannans (fungi) GH99 "mannan endo-1,2-alpha-mannanase" 3.2.1.198 "cellulose, chitin" CBM1 "Modules of approx. 40 residues found almost exclusively in fungi. The cellulose-binding function has been demonstrated in many cases, and appears to be mediated by three aromatic residues separated by about 10.4 angstrom and which form a flat surface. The only non-fungal occurence of CBM1 is in an algal non-hydrolytic polysaccharide-binding protein which is composed of four repeated CBM1 modules. Binding to chitin has been demonstrated in one case." - cellulose CBM10 Modules of approx. 50 residues. The cellulose-binding function has been demonstrated in one case. - "cellulose, mixed linked glucan" CBM11 "Modules of approx. 180-200 residues. The CBM11 of Clotridium thermocellum Cel26A-Cel5E has been shown to bind both beta-1,4-glucan and beta-1,3-1,4-mixed linked glucans." - chitin CBM12 Modules of approx. 40-60 residues. The majority of these modules is found among chitinases where the function is chitin-binding. Distantly related to the CBM5 family. - "plant lectin, xylan " CBM13 "Modules of approx. 150 residues which always appear as a threefold internal repeat. The only apparent exception to this, xylanase II of Actinomadura sp. FC7 (GenBank U08894), is in fact not completely sequenced. These modules were first identified in several plant lectins such as ricin or agglutinin of Ricinus communis which bind galactose residues. The three-dimensional structure of a plant lectin has been determined and displays a pseudo-threefold symmetry in accord with the observed sequence threefold repeat. These modules have since been found in a number of other proteins of various functions including glycoside hydrolases and glycosyltransferases. While in the plant lectins this module binds mannose, binding to xylan has been demonstrated in the Streptomyces lividans xylanase A and arabinofuranosidase B. Binding to GalNAc has been shown for the corresponding module of GalNAc transferase 4. For the other proteins, the binding specificity of these modules has not been established. The pseudo three-fold symmetry of the CBM13 module has now been confirmed in the 3-D structure of the intact, two-domain, xylanase of Streptomyces olivaceoviridis." - chitin CBM14 chitin binding IIa.chitin chitin CBM14 "Modules of approx. 70 residues. The chitin-binding function has been demonstrated in several cases. These modules are found attached to a number of chitinase catalytic domains, but also in non-catalytic proteins either in isolation or as multiple repeats" - xylan and xylooligosaccharide CBM15 Binding to xylan and xylooligosaccharides has been demonstrated in the case of Xyn10C of Cellvibrio mixtus. - cellulose and glucomannan CBM16 Carbohydrate-binding module 16. Binding to cellulose and glucomannan demonstrated [B. Bae et al (2008) J Biol Chem. 283:12415-25 (PMID: 18025086)] - "amorphous cellulose, cellooligosaccharides and derivatized cellulose" CBM17 "Modules of approx. 200 residues. Binding to amorphous cellulose, cellooligosaccharides and derivatized cellulose has been demonstrated." - chitin CBM18 "Modules of approx. 40 residues. The chitin-binding function has been demonstrated in many cases. These modules are found attached to a number of chitinase catalytic domains, but also in non-catalytic proteins either in isolation or as multiple repeats." - chitin CBM19 Modules of 60-70 residues with chitin-binding function. - "cellulose, chitin, xylan" CBM2 Modules of approx. 100 residues and which are found in a large number of bacterial enzymes. The cellulose-binding function has been demonstrated in many cases. Several of these modules have been shown to also bind chitin or xylan. - "granular starch, cyclodextrin" CBM20 The granular starch-binding function has been demonstrated in several cases. Interact strongly with cyclodextrins. Often designated as starch-binding domains (SBD). - granular starch CBM21 Modules of approx. 100 residues. The granular starch-binding function has been demonstrated in one case. Sometimes designated as starch-binding domains (SBD). - "xylan,1,3/beta-1,4-glucans" CBM22 "A xylan binding function has been demonstrated in several cases and affinity with mixed beta-1,3/beta-1,4-glucans in one. In several cases a thermostabilizing effect has also been seen." - mannan CBM23 Mannan-binding function demonstrated in one case. - mutan CBM24 "alpha-1,3-glucan (mutan)-binding function demonstrated in two cases (PMID:10636904)" - starch CBM25 Starch-binding function demonstrated in one case. - starch CBM26 Starch-binding function demonstrated in two cases. - mannan CBM27 Mannan-binding function demonstrated in two cases - "non-crystalline cellulose, cellooligosaccharides, and beta-(1,3)(1,4)-glucans" CBM28 "The module from the endo-1,4-glucanase of Bacillus sp. 1139 binds to non-crystalline cellulose, cellooligosaccharides, and beta-(1,3)(1,4)-glucans" - "mannan,glucomannan" CBM29 Binding to mannan/glucomannan has been demonstrated. - "cellulose,chitin" CBM3 Modules of approx. 150 residues found in bacterial enzymes. The cellulose-binding function has been demonstrated in many cases. In one instance binding to chitin has been reported. - cellulose CBM30 Binding to cellulose has been demonstrated for the N-terminal module of Fibrobacter succinogenes CelF. - "beta-1,3-xylan" CBM31 "Binding to beta-1,3-xylan has been demonstrated for the C-terminal module of the beta-1,3-xylanase of Alcaligenes sp. XY234." - "galactose, lactose, LacNAc" CBM32 "Binding to galactose and lactose has been demonstrated for the module of Micromonospora viridifaciens sialidase (PMID: 16239725). Binding to polygalacturonic acid has been shown for a Yersinia member (PMID: 17292916). Binding to LacNAc (beta-D-galactosyl-1,4-beta-D-N-acetylglucosamine) has been shown for an N-acetylglucosaminidase from Clostridium perfingens (PMID: 16990278)." - "cellulose, chitin" CBM33 Copper-dependent lytic polysaccharide monooxygenases now reclassified in family AA10 - granular starch CBM34 Modules of approx. 120 residues. Granular starch-binding function has been demonstrated in the case of Thermoactinomyces vulgaris R-47 alpha-amylase 1 (TVAI). - "xylan,decorated soluble mannan and mannooligosaccharide,beta-galactan" CBM35 "Modules of approx. 130 residues. A module that is conserved in three Cellvibrio xylan-degrading enzymes binds to xylan and the interaction is calcium dependent, while a module from a Cellvibrio mannanase binds to decorated soluble mannans and mannooligosaccharides. A module in a Phanerochaete chrysosporium galactan 1,3-beta-galactosidase binds to beta-galactan." - xylan and xylooligosaccharide CBM36 "Modules of approx. 120-130 residues displaying structural similarities to CBM6 modules. The only CBM36 currently characterised, that from Paenbacillus polymyxa xylanase 43A, shows calcium-dependent binding of xylans and xylooligosaccharides. X-ray crystallography shows that there is a direct interaction between calcium and ligand." - "xylan, chitin, microcrystalline and phosphoric-acid swollen cellulose, as well as more heterogeneous substrates, such as alfalfa cell walls, banana stem and wheat straw." CBM37 "Modules of approx. 100 residues, conserved in numerous R. albus polysaccharide-degrading enzymes and other proteins from this bacterium. Several members of CBM37 have been shown to exhibit rather broad binding specificity to xylan, chitin, microcrystalline and phosphoric-acid swollen cellulose, as well as more heterogeneous substrates, such as alfalfa cell walls, banana stem and wheat straw." - inulin CBM38 The inulin-binding function has been demonstrated in the case of the cycloinulo-oligosaccharide fructanotransferase from Paenibacillus macerans (Bacillus macerans) by Lee et al. (2004) FEMS Microbiol Lett 234:105-10. (PMID:15109727). - "beta-1,3-glucan,lipopolysaccharide and lipoteichoic acid" CBM39 "Modules generally found at the N-terminus of a GH16 module (itself frequently lacking a catalytic machinery) and more seldomly in isolation. The beta-1,3-glucan binding function has been demonstrated, along with binding to lipopolysaccharide and lipoteichoic acid." - "xylan, beta-1,3-glucan, beta-1,3-1,4-glucan, beta-1,6-glucan and amorphous cellulose" CBM4 "Modules of approx. 150 residues found in bacterial enzymes. Binding of these modules has been demonstrated with xylan, beta-1,3-glucan, beta-1,3-1,4-glucan, beta-1,6-glucan and amorphous cellulose but not with crystalline cellulose." - sialic acid CBM40 "Modules of approx. 200 residues, found at the N-terminus of GH33 sialidases. Can also be found inserted in the beta-propeller of GH33 sialidases. The sialic acid binding function has been demonstrated for the N-terminal CBM40 of Vibrio cholerae sialidase (Moustafa et al. (2004) J Biol Chem 279:40819-26) (PMID: 15226294)." - "alpha-glucans amylose, amylopectin, pullulan, and oligosaccharide fragments derived from these polysaccharides" CBM41 "Modules of approx. 100 residues found in primarily in bacterial pullulanases. The N-terminal module from Thermotoga maritima Pul13 has been shown to bind to the alpha-glucans amylose, amylopectin, pullulan, and oligosaccharide fragments derived from these polysaccharides (Lammerts van Bueren et al. (2004) Biochemistry 43:15633-42) (PMID: 15581376)." - arabinoxylan CBM42 Modules of approx. 160 residues found mostly at the C-terminus of GH54 catalytic domains. Binding to arabinofuranose (present in arabinoxylan) has been demonstrated. - "beta-1,3-glucan" CBM43 "Modules of approx. 90-100 residues found at the C-terminus of GH17 or GH72 enzymatic modules and also sometimes isolated. CBM43 modules sometimes carry a C-terminal membrane anchor. The beta-1,3-glucan binding function has been demonstrated with the olive pollen protein Ole e 10." - cellulose and xyloglucan CBM44 The C-terminal CBM44 module of the Clostridium thermocellum enzyme has been demonstrated to bind equally well cellulose and xyloglucan - starch CBM45 "Modules of approx. 100 residues, found at the N-terminus of plastidial alpha-amylases and of alpha-glucan, water dikinases. Starch-binding activity demonstrated in the case of potato alpha-glucan, water dikinase." - cellulose CBM46 "Modules of approx. 100 residues, found at the C-terminus of several GH5 cellulases. Cellulose-binding function demonstrated in one case." - fucose CBM47 Modules of approx 150 residues. Fucose-binding activity demonstrated - glycogen CBM48 "Modules of approx. 100 residues with glycogen-binding function, appended to GH13 modules. Also found in the beta subunit (glycogen-binding) of AMP-activated protein kinases (AMPK)" - crystalline cellulose CBM49 Modules of approx. 100 residues found at the C-terminus of plant GH9 enzymes. Distantly related to CBM2 modules. Binding to crystalline cellulose demonstrated in the case of Solanum lycopersicum Cel8 enzyme (SlCel9C1). - chitin CBM5 Modules of approx. 60 residues found in bacterial enzymes. Chitin-binding described in several cases. Distantly related to the CBM12 family. - chitin or peptidoglycan CBM50 "Modules of approx. 50 residues found attached to various enzymes from families GH18, GH19, GH23, GH24, GH25 and GH73, i.e. enzymes cleaving either chitin or peptidoglycan. Binding to chitopentaose demonstrated in the case of Pteris ryukyuensis chitinase A [Ohnuma T et al. (2008) J. Biol. Chem. 283:5178-87 (PMID: 18083709)]. CBM50 modules are also found in a multitude of other enzymes targeting the petidoglycan such as peptidases and amidases. These enzymes are not reported in the list below." - galactose and to blood group A/B-antigens CBM51 "Modules of approx. 150 residues found attached to various enzymes from families GH2, GH27, GH31, GH95, GH98 and GH101 . Binding to galactose and to blood group A/B-antigens demonstrated in the case of C. perfringens GH95CBM51 and GH98CBM51 respectively [Gregg KJ et al. (2008) J. Biol. Chem. 283:12604-13 PMID: 18292090]." - "beta-1,3-glucan" CBM52 "Modules of approx. 60 residues attached to a few GH81 enzymes but present in other proteins. Binding to beta-1,3-glucan demonstrated for Schizosaccharomyces pombe 972h- endo-1,3-beta-glucanase Eng1 [Martin-Quadrado et al., Mol. Microbiol. (2008) 69:188-200 PMID:18466295]" - starch CBM53 Starch-binding function demonstrated by Valdez et al. (2008) [PMID: 18260645] - "xylan, yeast cell wall glucan and chitin" CBM54 "Binding to xylan, yeast cell wall glucan and chitin shown in Dvortsov et al., Microbiology UK (2009) in press." - chitin CBM55 "Binding to chitin demonstrated in the case of the CBM55 of Entamoeba histolytica chitinase (Van Dellen et al. (2002) Infect Immun. 70:3259-3263,PMID: 12011021)." - "beta-1,3-glucan" CBM56 "beta-1,3-glucan binding function demonstrated by Yamamoto et al. (1998) FEBS Letters 433:41-43 [PMID: 9738929]" - glycosidases CBM57 Created from reading Schallus et al (2008) Mol Biol Cell. 19:3404-3414 [PMID: 18524852] and finding related domains attached to various glycosidases. - maltoheptaose CBM58 The CBM58 module of the Bacteroides thetaiotaomicron SusG protein has been shown to bind maltoheptaose - "mannan, xylan, and cellulose" CBM59 "Binding to mannan, xylan, and cellulose demonstrated for the CBM59 of ManF-X10 xylanase from an environmental genomic DNA library (Li et al. (2009) World Journal of Microbiology and Biotechnology 25:2071-2078,doi:10.1007/s11274-009-0111-6)" - "amorphous cellulose, beta-1,4-xylan,beta-1,3-glucan, beta-1,3-1,4-glucan, and beta-1,4-glucan" CBM6 "Modules of approx. 120 residues. The cellulose-binding function has been demonstrated in one case on amorphous cellulose and beta-1,4-xylan. Some of these modules also bind beta-1,3-glucan, beta-1,3-1,4-glucan, and beta-1,4-glucan." - xylan CBM60 Modules of approx 120 residues usually found appended to xylanases. The xylan-binding function and the relatedness (circular permutation) to family CBM36 has been demonstrated [PMID: 20659893]. - "beta-1,4-galactan" CBM61 "Modules of approx. 150 residues found appended to GH16, GH30, GH31, GH43, GH53 and GH66 catalytic domains. A beta-1,4-galactan binding function has been demonstrated for the CBM61 of Thermotoga maritima GH53 galactanase [PMID: 20826814]." - "xyloglucan, arabinogalactan and galactomannan" CBM62 "The CBM62 module of Clostridium thermocellum Cthe_2193 protein binds galactose moieties found on xyloglucan, arabinogalactan and galactomannan." - cellulose CBM63 The CBM63 module of Bacillus subtilis expansin EXLX1 has been shown to bind cellulose. - cellulose CBM64 "Module found at C-term of several Spirochaeta thermophila proteins. Binding to cellulose shown by Angelov, Loderer, Pompei Liebl (2011) AEM, 77:5483-5489 [PMID - 21685171]" - xyloglucan CBM65 "CBM65A and CBM65B, derived from Eubacterium cellulosolvens endoglucanase EcCel5A, bind to a range of beta-glucans but, uniquely, display significant preference for xyloglucan" - fructan CBM66 "The CBM66 module, derived from the Bacillus subtilis exo-acting beta-fructosidase SacC, targets the terminal fructoside residue of fructans." - L-rhamnose CBM67 Fujimoto et al. [PMID : 23486481] disclosed the L-rhamnose binding activity and 3-D structure of the CBM67 of Streptomyces avermitilis alpha-L-rhamnosidase (SaRha78A) - maltotriose and maltotetraose CBM68 "Binding to maltotriose and maltotetraose shown for the pullulanase of Anoxybacillus sp. LM18-11. Binding function derived from crystal structure and deletion of the CBM, which showed reduced specific activity and increased Km value compared to the wild type enzyme." - starch CBM69 "starch-binding function demonstrated in one case, distantly related to families CBM20 and CBM48" - hyaluronan CBM70 The hyaluronan-specific binding function of the N-terminal CBM70 module of Streptococcus pneumoniae hyaluronate lyase has been demonstrated. - lactose and LacNAc CBM71 The two CBM71s of S. pneumoniae BgaA bind lactose and LacNAc. - "broad spectrum of polysaccharides including soluble and insoluble cellulose, beta-1,3/1,4-mixed linked glucans, xylan, and beta-mannan " CBM72 "Modules of 130-180 residues found at the C-terminus glycoside hydrolases from various families, sometimes as tandem repeats. The CBM72 found on an endoglucanase from an uncultivated microorganism was found to bind a broad spectrum of polysaccharides including soluble and insoluble cellulose, beta-1,3/1,4-mixed linked glucans, xylan, and beta-mannan [PMID=26765840]." - chitin CBM73 Modules of approx 65 residues found on various enzymes active of chitin. Chitin-binding function demonstrated for the Cellvibrio japonicus CjLPMO10A protein. - starch CBM74 Modules of approx. 300 residues appended to several alpha-amylases. The starch-binding function has been demonstrated for the CBM74 appended to the GH13 alpha-amylase of Microbacterium aureum B8.A - xyloglucan CBM75 Modules of 290 residues appended to GH43_16 enzymes. So far found exclusively in Ruminococci. The xyloglucan-binding function was demonstrated for the R. flavefaciens protein. - "xyloglucan, glucomannan, and barley beta-glucan" CBM76 "Modules of approx. 170 residues appended to GH44 enzymes. So far found exclusively in Ruminococci. Broad specificity binding to beta-glucans demontsrated for the R. flavefaciens module, which binds xyloglucan, glucomannan, and barley beta-glucan." - various CBM77 Pectin binding modules of approx. 110 residues. The Ruminococcus flavefaciens CBM77 was shown to bind various pectins of low degree of esterification. - "beta-1,4-glucans" CBM78 "Modules of approx. 150 residues appended to the C-terminus of GH5 and GH26 enzymes. So far found exclusively in Ruminococcal enzymes. The R. flavefaciens module has been shown to bind decorated beta-1,4-glucans with a preference for xyloglucan." - beta-glucans CBM79 Modules of approx. 130 residues found so far only in ruminococcal proteins. Binding to various beta-glucans was shown for the R. flavefaciens GH9 enzyme. - cellulose CBM8 The cellulose-binding module from a cellulase of the slime mold Dictyostelium discoideum has been experimentally shown to bind cellulose. - "beta-glycans (xyloglucan, glucomannan, galactomannan, barley beta-glucan)" CBM80 "Modules of approx. 90 residues found so far only in ruminococcal enzymes of families GH5 or GH26. Broad specificity for beta-glycans (xyloglucan, glucomannan, galactomannan, barley beta-glucan)." - "beta-1,4-, beta-1,3,-glucans, xyloglucan, avicel and cellooligosaccharides" CBM81 "Small family of modules of approx. 100 residues, appended to GH5_2 enzymes. So far found exclusively in a few gammaproteobacteria. The CBM81 from an uncultivated species was shown to have binding affinity for beta-1,4-, beta-1,3,-glucans, xyloglucan, avicel and cellooligosaccharides." - starch CBM82 "The boundaries, structure and starch-binding function of the CBM82 module of Eubacterium rectale Amy13K have been reported by Cockburn and coworkers in Molec. Microbiol. (2017) (PMID=29139580)" - starch CBM83 "The boundaries, structure and starch-binding function of the CBM83 module of Eubacterium rectale Amy13K have been reported by Cockburn and coworkers in Molec. Microbiol. (2017) (PMID=29139580)" - xanthan CBM84 "Modules of approx. 140 aminoacids appended to enzymes of different families of CAZymes. A xanthan-binding function was reported for the GH9 xanthanase of Paenibacillus nanensis by Moroz et al. ACS Catal., 2018, 8 (7), pp 6021-6034." - "glycans (cellulose, glucuronoxylan, b-1,3-1,4-glucan and glucomannan)" CBM85 "Created after Fredriksen et al. (2019) PMID=30635385; binds to a broad range of glycans (cellulose, glucuronoxylan, b-1,3-1,4-glucan and glucomannan)" - xylan CBM86 "Created after the report of an activity [Leth et al. (2018), Nat. Microbiol, PMID:29610517] and a structure [Leth et al. (2019), FEBS J, PMID:31693302] of a xylan-binding module in the Xyn10A protein of Roseburia intestinalis L1-82." - galactosaminogalactan CBM87 "Binding to alpha-1,4-N-acetylgalactosamine-rich regions of galactosaminogalactan" - galactoxyloglucan and galactomannan CBM88 Binding to terminal galactose in galactoxyloglucan and galactomannan - xylan CBM89 - - cellulose CBM9 Modules of approx. 170 residues found so far only in xylanases. The cellulose-binding function has been demonstrated in one case. - lignin AA1 Laccase / p-diphenol:oxygen oxidoreductase / ferroxidase 1.10.3.2 lignin AA1 ferroxidase 1.10.3.- lignin AA1 Laccase-like multicopper oxidase 1.10.3.- cellulose AA10 lytic cellulose monooxygenase (C4-dehydrogenating) 1.14.99.56 cellulose AA10 lytic cellulose monooxygenase (C1-hydroxylating) 1.14.99.54 chitin AA10 lytic chitin monooxygenase 1.14.99.53 xylan AA10 lytic xylan monooxygenase / xylan oxidase (glycosidic bond-cleaving) 1.14.99.- chitin AA11 AA11 proteins are copper-dependent lytic polysaccharide monooxygenases (LPMOs). cleavage of chitin chains with oxidation of C-1 has been demonstrated for a AA11 LPMO from Aspergillus oryzae - "pyrroloquinoline quinone (PQQ, polyphenol)" AA12 The pyrroloquinoline quinone-dependent oxidoreductase activity was demonstrated for the CC1G_09525 protein of Coprinopsis cinerea. - starch AA13 lytic starch monooxygenase / starch oxidase (glycosidic bond-cleaving) 1.14.99.55 xylan AA14 AA14 proteins are copper-dependent lytic polysaccharide monooxygenases (LPMOs).cleavage of xylan with oxidation of C-1 has been demonstrated for two AA14 LPMOs from Trametes coccinea (Pycnoporus coccineus) - xylan AA14 lytic xylan monooxygenase / xylan oxidase (glycosidic bond-cleaving) 1.14.99.- cellulose AA15 lytic cellulose monooxygenase (C1-hydroxylating) 1.14.99.54 chitin AA15 lytic chitin monooxygenase 1.14.99.53 cellulose AA16 Lytic cellulose monooxygenase (C1-hydroxylating) 1.14.99.54 pectin AA17 Lytic polygalacturonic acid monooxygenase (C4-hydroxylating) 1.14.99.- pectin AA17 Lytic polygalacturonic acid monooxygenase (C4-hydroxylating) 1.14.99.- lignin AA2 cytochrome-c peroxidase 1.11.1.5 lignin AA2 versatile peroxidase 1.11.1.16 lignin AA2 lignin peroxidase 1.11.1.14 lignin AA2 manganese peroxidase 1.11.1.13 lignin AA2 ascorbate peroxidase 1.11.1.11 lignin AA2 peroxidase 1.11.1.- cellulose AA3 cellobiose dehydrogenase 1.1.99.18 lignin AA3 aryl alcohol oxidase 1.1.3.7 lignin AA3 glucose 1-oxidase 1.1.3.4 lignin AA3 alcohol oxidase 1.1.3.13 lignin AA3 pyranose oxidase 1.1.3.10 lignin AA4 vanillyl-alcohol oxidase 1.1.3.38 lignin AA5 glyoxal oxidase 1.2.3.15 lignin AA5 galactose oxidase 1.1.3.9 lignin AA5 alcohol oxidase 1.1.3.13 lignin AA5 Oxidase with oxygen as acceptor 1.1.3.- lignin AA5 raffinose oxidase 1.1.3.- lignin AA6 "1,4-benzoquinone reductase" 1.6.5.6 glucooligosaccharide AA7 glucooligosaccharide oxidase 1.1.3.- chitooligosaccharide AA7 chitooligosaccharide oxidase 1.1.3.- cellooligosaccharide AA7 cellooligosaccharide dehydrogenase 1.1.99.- lignin AA8 Iron reductase domain - cellulose AA9 lytic cellulose monooxygenase (C4-dehydrogenating) 1.14.99.56 cellulose AA9 lytic cellulose monooxygenase (C1-hydroxylating) 1.14.99.54 cellulose AA9 AA9 (formerly GH61) proteins are copper-dependent lytic polysaccharide monooxygenases (LPMOs).cleavage of cellulose chains with oxidation of carbons C1 and/or C4 and C-6) - - CE0 See below. - S-formylglutathione(ester) CE1 S-formylglutathione hydrolase 3.1.2.12 Feruloyl-polysaccharide(esterified sugar) CE1 feruloyl esterase 3.1.1.73 xylan CE1 acetyl xylan esterase 3.1.1.72 A carboxylic ester(ester) CE1 carboxylesterase 3.1.1.1 "Acyl-CoA,Palmitoyl-CoA and other long-chain acyl-CoAs(ester)" CE1 diacylglycerol O-acyltransferase 2.3.1.20 trehalose CE1 trehalose 6-O-mycolyltransferase 2.3.1.122 Hydroxycinnamic acids(Phenolic acids) CE1 cinnamoyl esterase 3.1.1.- choline esters(ester) CE10 cholinesterase 3.1.1.8 acetic esters(ester) CE10 acetylcholinesterase 3.1.1.7 triglycerides CE10 carboxyl esterase 3.1.1.3 "sterol, long-chain fatty acid(ester)" CE10 sterol esterase 3.1.1.13 Brefeldin A(ester) CE10 brefeldin A esterase 3.1.1.-. arylesterase(ester) CE10 arylesterase 3.1.1.- biosynthesis of lipid A CE11 UDP-3-0-acyl N-acetylglucosamine deacetylase 3.5.1.108 acetyl xylan CE12 acetyl xylan esterase 3.1.1.72 pectin CE12 pectin acetylesterase 3.1.1.- pectin CE12 rhamnogalacturonan acetylesterase 3.1.1.- pectin CE13 pectin acetylesterase 3.1.1.- glycosylphosphatidylinositol(lipid anchor ) CE14 N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase 3.5.1.89 chitin CE14 diacetylchitobiose deacetylase 3.5.1.- alkylating agents and xenobiotics(organic compound) CE14 mycothiol S-conjugate amidase 3.5.1.- lignin CE15 4-O-methyl-glucuronoyl methylesterase 3.5.1.- various carbohydrate acetyl ester CE16 acetylesterase (active on various carbohydrate acetylesters) 3.1.1.6 acetylmannan CE17 acetylmannan esterase 3.1.1.- pectin CE19 Family created after Bamford and coworkers [PMID=28329766] demonstrated the pectin methylesterase activity of BT1017 protein from Bacteroides thetaiotaomicron VPI-5482 - acetylxylan CE2 acetyl xylan esterase 3.1.1.72 acetylxylan CE3 acetyl xylan esterase 3.1.1.72 chitin CE4 chitin deacetylase 3.5.1.41 Chitooligosaccharides CE4 chitooligosaccharide deacetylase 3.5.1.- peptidoglycan CE4 peptidoglycan GlcNAc deacetylase 3.5.1.- peptidoglycan CE4 peptidoglycan N-acetylmuramic acid deacetylase 3.5.1.- acetylxylan CE4 acetyl xylan esterase 3.1.1.72 cutin CE5 cutinase 3.1.1.74 acetylxylan CE5 acetyl xylan esterase 3.1.1.72 acetylxylan CE6 acetyl xylan esterase 3.1.1.72 acetylxylan CE7 acetyl xylan esterase 3.1.1.72 cephalosporin C(antibiotic) CE7 cephalosporin-C deacetylase 3.1.1.41 pectin CE8 pectin methylesterase 3.1.1.11 host glycan CE9 N-acetylglucosamine 6-phosphate deacetylase 3.5.1.25 - PL0 Polysaccharide lyases not yet assigned to a family. - pectin PL1 pectin lyase 4.2.2.10 pectate PL1 pectate lyase 4.2.2.2 homogalacturonan(de-esterified pectin) PL1 exo-pectate lyase 4.2.2.9 pectate PL10 pectate lyase 4.2.2.2 rhamnogalacturonan I(pectin from the plant cell wall) PL11 rhamnogalacturonan endolyase 4.2.2.23 rhamnogalacturonan I(pectin from the plant cell wall) PL11 rhamnogalacturonan exolyase 4.2.2.24 Heparin and heparan sulfate(host glycan) PL12 heparin lyase / heparin lyase I 4.2.2.7 heparin sulfate(host glycan) PL12 heparin-sulfate lyase 4.2.2.8 Heparin and heparan sulfate(host glycan) PL13 heparin lyase 4.2.2.7 host glycan PL14 "beta-1,4-glucuronan lyase" 4.2.2.14 alginate PL14 exo-oligoalginate lyase 4.2.2.26 alginate PL14 poly(beta-mannuronate) lyase / M-specific alginate lyase 4.2.2.3 alginate PL15 oligoalginate lyase / exo-alginate lyase 4.2.2.26 alginate PL15 alginate lyase 4.2.2.3 Heparin and heparan sulfate(host glycan) PL15 heparin lyase / heparin lyase I 4.2.2.7 heparin sulfate(host glycan) PL15 heparin-sulfate lyase / heparin lyase III 4.2.2.8 hyaluronan PL16 hyaluronan lyase 4.2.2.1 alginate PL17 oligoalginate lyase 4.2.2.26 alginate PL17 alginate lyase 4.2.2.3 alginate PL18 poly(alpha-L-guluronate) lyase / G-specific alginate lyase 4.2.2.11 alginate PL18 alginate lyase 4.2.2.3 pectate PL2 pectate lyase 4.2.2.2 homogalacturonan(de-esterified pectin) PL2 exo-polygalacturonate lyase 4.2.2.9 host glycan PL20 "endo-beta-1,4-glucuronan lyase" 4.2.2.14 Heparin and heparan sulfate(host glycan) PL21 heparin lyase 4.2.2.7 heparin sulfate(host glycan) PL21 heparin-sulfate lyase 4.2.2.8 pectin( D-galacturonate) PL22 oligogalacturonate lyase / oligogalacturonide lyase 4.2.2.6 rhamnogalacturonan I(pectin from the plant cell wall) PL26 rhamnogalacturonan exolyase 4.2.2.24 glycosaminoglycans(host glycan) PL29 chondroitin-sulfate ABC endolyase 4.2.2.20 pectate PL3 pectate lyase 4.2.2.2 hyaluronate(host glycan) PL30 hyaluronate lyase 4.2.2.1 host glycan PL31 "endo-beta-1,4-glucuronan lyase" 4.2.2.14 alginate PL31 poly(beta-mannuronate) lyase / M-specific alginate lyase 4.2.2.3 alginate PL32 poly(beta-mannuronate) lyase / M-specific alginate lyase 4.2.2.3 hyaluronate(host glycan) PL33 hyaluronate lyase 4.2.2.1 glycosaminoglycans(host glycan) PL33 chondroitin sulfate lyase 4.2.2.20 gellan(polysaccharide) PL33 gellan lyase 4.2.2.25 alginate PL36 poly(beta-mannuronate) lyase / M-specific alginate lyase 4.2.2.3 glycosaminoglycans(host glycan) PL37 chondroitin-sulfate ABC endolyase 4.2.2.20 heparin sulfate(host glycan) PL37 heparin-sulfate lyase / heparin lyase III 4.2.2.8 host glycan PL38 "endo-beta-1,4-glucuronan lyase" 4.2.2.14 rhamnogalacturonan I(pectin from the plant cell wall) PL4 rhamnogalacturonan endolyase 4.2.2.23 alginate PL41 alginate lyase 4.2.2.3 arabinogalactan PL42 "L-rhamnose-¦Á-1,4-D-glucuronate lyase " 4.2.2.- arabinogalactan PL42 "L-Rh¦Á-¦Á-1,4-GlcA ¦Á-L-rhamnohydrolase" 3.2.1.- host glycan PL5 "endo-beta-1,4-glucuronan lyase" 4.2.2.14 alginate PL5 alginate lyase 4.2.2.3 alginate PL6 poly(alpha-L-guluronate) lyase / G-specific alginate lyase 4.2.2.11 dermatan sulfate(host glycan) PL6 chondroitinase B 4.2.2.19 alginate PL6 oligoalginate lyase / exo-alginate lyase 4.2.2.26 alginate PL6 MG-specific alginate lyase 4.2.2.- alginate PL6 alginate lyase 4.2.2.3 alginate PL7 alpha-L-guluronate lyase / G-specific alginate lyase 4.2.2.11 glucuronan(host glycan) PL7 "endo-beta-1,4-glucuronan lyase" 4.2.2.14 alginate PL7 oligoalginate lyase / exo-alginate lyase 4.2.2.26 alginate PL7 poly-(MG)-lyase / MG-specific alginate lyase 4.2.2.- alginate PL7 poly(beta-mannuronate) lyase / M-specific alginate lyase 4.2.2.3 hyaluronan PL8 hyaluronate lyase 4.2.2.1 xanthan PL8 xanthan lyase 4.2.2.12 glycosaminoglycans(host glycan) PL8 chondroitin ABC lyase 4.2.2.20 alginate PL8 poly(beta-mannuronate) lyase / M-specific alginate lyase 4.2.2.3 glycosaminoglycans(host glycan) PL8 chondroitin AC lyase 4.2.2.5 Heparin and heparan sulfate(host glycan) PL8 heparin lyase / heparin lyase I 4.2.2.7 pectate PL9 pectate lyase 4.2.2.2 rhamnogalacturonan I(pectin from the plant cell wall) PL9 rhamnogalacturonan endolyase 4.2.2.23 homogalacturonan(de-esterified pectin) PL9 exopolygalacturonate lyase 4.2.2.9