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CAZyme Information: MGYG000001450_00298

You are here: Home > Sequence: MGYG000001450_00298

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Nesterenkonia massiliensis
Lineage Bacteria; Actinobacteriota; Actinomycetia; Actinomycetales; Micrococcaceae; Nesterenkonia; Nesterenkonia massiliensis
CAZyme ID MGYG000001450_00298
CAZy Family GT28
CAZyme Description UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
368 MGYG000001450_1|CGC2 38864.62 9.0002
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000001450 2641047 Isolate not provided Europe
Gene Location Start: 318179;  End: 319285  Strand: -

Full Sequence      Download help

MSAPSVVLAG  GGTAGHISPM  LAIAEAIHRL  APQARQSMIG  TPAGLETRLV  PEAGYELDLI60
EKVPFPRRPT  RDLLRFPGRF  RSAINAAGEI  LDRREAEVVV  GVGGYVCTPV  YLAARRRGIP120
VVLHEANARP  GLANKLGNRF  SAFSGVAFEN  TPLRGAEHVG  MPMAQAISRL  DRDAERATAR180
QALGLDPQRP  TLVVTGGSSG  ALNVNRALAS  ALPEILSTGA  QVLHLTGRGK  VVTDANGAPL240
RAEHYHQREY  LDGMHLAYAA  ADLIVARAGA  ATVCEVAAVG  LPAVFVPLPI  GNGEQELNAR300
GLVDAGGALL  VKDEHFSKSW  IRRNVLPLLK  DPRLLLTMQQ  HSEASGIADA  DERMARAALH360
AAGVEAQV368

Enzyme Prediction      help

No EC number prediction in MGYG000001450_00298.

CAZyme Signature Domains help

Created with Snap1836557392110128147165184202220239257276294312331349191349GT28
Family Start End Evalue family coverage
GT28 191 349 1.9e-45 0.9872611464968153

CDD Domains      download full data without filtering help

Created with Snap18365573921101281471651842022202392572762943123313494363murG5355GT28_MurG5355murG6359MurG191354Glyco_tran_28_C
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
PRK00726 murG 6.29e-104 4 363 2 356
undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional
cd03785 GT28_MurG 8.44e-94 5 355 1 348
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. MurG (EC 2.4.1.227) is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
TIGR01133 murG 2.44e-76 5 355 2 345
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. RM 8449890 RT The final step of peptidoglycan subunit assembly in Escherichia coli occurs in the cytoplasm. RA Bupp K, van Heijenoort J. RL J Bacteriol 1993 Mar;175(6):1841-3 [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
COG0707 MurG 2.41e-74 6 359 3 352
UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell wall/membrane/envelope biogenesis].
pfam04101 Glyco_tran_28_C 6.72e-35 191 354 1 166
Glycosyltransferase family 28 C-terminal domain. The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (EC 2.4.1.-). Structural analysis suggests the C-terminal domain contains the UDP-GlcNAc binding site.

CAZyme Hits      help

Created with Snap18365573921101281471651842022202392572762943123313494361ADX72721.1|GT284361BCW18891.1|GT284361SDT17373.1|GT284361QDG87950.1|GT284355QDG63961.1|GT28
Hit ID E-Value Query Start Query End Hit Start Hit End
ADX72721.1 2.37e-153 4 361 6 363
BCW18891.1 9.58e-153 4 361 6 363
SDT17373.1 3.88e-152 4 361 6 363
QDG87950.1 1.11e-151 4 361 6 363
QDG63961.1 1.11e-151 4 355 6 357

PDB Hits      download full data without filtering help

Created with Snap183655739211012814716518420222023925727629431233134963551F0K_A53623S2U_A63437D1I_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
1F0K_A 8.93e-43 6 355 9 347
The1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1F0K_B The 1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1NLM_A Crystal Structure Of Murg:glcnac Complex [Escherichia coli],1NLM_B Crystal Structure Of Murg:glcnac Complex [Escherichia coli]
3S2U_A 1.07e-34 5 362 4 355
Crystalstructure of the Pseudomonas aeruginosa MurG:UDP-GlcNAc substrate complex [Pseudomonas aeruginosa PAO1]
7D1I_A 3.90e-32 6 343 12 351
ChainA, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_B Chain B, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_C Chain C, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii]

Swiss-Prot Hits      download full data without filtering help

Created with Snap18365573921101281471651842022202392572762943123313495361sp|A0JV94|MURG_ARTS25361sp|A1R5F8|MURG_PAEAT6359sp|A1SL80|MURG_NOCSJ6352sp|Q820F6|MURG_STRAW6352sp|Q9ZBA5|MURG_STRCO
Hit ID E-Value Query Start Query End Hit Start Hit End Description
A0JV94 5.16e-151 5 361 7 363
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Arthrobacter sp. (strain FB24) OX=290399 GN=murG PE=3 SV=1
A1R5F8 3.50e-143 5 361 13 369
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Paenarthrobacter aurescens (strain TC1) OX=290340 GN=murG PE=3 SV=1
A1SL80 1.86e-121 6 359 3 356
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Nocardioides sp. (strain ATCC BAA-499 / JS614) OX=196162 GN=murG PE=3 SV=1
Q820F6 1.39e-115 6 352 3 348
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680) OX=227882 GN=murG PE=3 SV=1
Q9ZBA5 1.65e-114 6 352 3 348
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) OX=100226 GN=murG PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000062 0.000001 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000001450_00298.