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CAZyme Information: MGYG000000008_00525

You are here: Home > Sequence: MGYG000000008_00525

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Lactobacillus johnsonii
Lineage Bacteria; Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae; Lactobacillus; Lactobacillus johnsonii
CAZyme ID MGYG000000008_00525
CAZy Family GT4
CAZyme Description Glycosyltransferase Gtf1
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
374 MGYG000000008_3|CGC2 42566.58 9.9629
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000008 1971706 Isolate United Kingdom Europe
Gene Location Start: 97526;  End: 98650  Strand: +

Full Sequence      Download help

MKILIVIDDY  FNKSNGMSIS  TQRFVREFKK  MDQDVRILSS  IAGGEPDYPL  PIMTIPVFKN60
IIAKEGFHFA  KPKKEIIKEA  IRWADLVHLE  DPFPVCWTAA  KIAKQMRKPI  TGTFHLYPEN120
LTASVPILDH  ASINSAFMRL  FRDTTFNYCS  YLQCPTLKVE  QRLKKYNFKS  KLIVISNGIS180
DYYLQSNQRT  TTTDPFTILS  IGRFSNEKDQ  KTLIKAIGRS  KYKDRIKLIL  AGKGPLKNEY240
ISLCQRLKIN  AQLGFYSRND  LKQIMDQSNI  VVHCANVEVE  GMACMEAFAT  GCVPIIAQSP300
LSSTSSYALS  PNNLFPAGSS  EILAQRIDYW  INHPKDLKMM  SANYQNYAKS  LTVQFSAKKL360
LTMMKNAQKN  YLSN374

Enzyme Prediction      help

No EC number prediction in MGYG000000008_00525.

CAZyme Signature Domains help

Created with Snap1837567493112130149168187205224243261280299317336355193299GT4
Family Start End Evalue family coverage
GT4 193 299 2.2e-19 0.68125

CDD Domains      download full data without filtering help

Created with Snap18375674931121301491681872052242432612802993173363552364GT4_UGDG-like1361RfaB2343GT4_PimA-like194343Glycos_transf_12297GT4_GT28_WabH-like
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd03817 GT4_UGDG-like 3.66e-53 2 364 1 372
UDP-Glc:1,2-diacylglycerol 3-a-glucosyltransferase and similar proteins. This family is most closely related to the GT1 family of glycosyltransferases. UDP-glucose-diacylglycerol glucosyltransferase (EC 2.4.1.337, UGDG; also known as 1,2-diacylglycerol 3-glucosyltransferase) catalyzes the transfer of glucose from UDP-glucose to 1,2-diacylglycerol forming 3-D-glucosyl-1,2-diacylglycerol.
COG0438 RfaB 9.64e-34 1 361 1 371
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis].
cd03801 GT4_PimA-like 9.19e-32 2 343 1 343
phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.
pfam00534 Glycos_transf_1 3.27e-23 194 343 1 154
Glycosyl transferases group 1. Mutations in this domain of PIGA lead to disease (Paroxysmal Nocturnal haemoglobinuria). Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars. The eukaryotic glycogen synthases may be distant members of this family.
cd03811 GT4_GT28_WabH-like 2.37e-21 2 297 1 291
family 4 and family 28 glycosyltransferases similar to Klebsiella WabH. This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core.

CAZyme Hits      help

Created with Snap18375674931121301491681872052242432612802993173363551374AZZ67455.1|GT41374AOG25593.1|GT41374AEB93234.1|GT41374QIA87510.1|GT41374QXL46789.1|GT4
Hit ID E-Value Query Start Query End Hit Start Hit End
AZZ67455.1 5.79e-269 1 374 1 374
AOG25593.1 5.79e-269 1 374 1 374
AEB93234.1 5.79e-269 1 374 1 374
QIA87510.1 5.79e-269 1 374 1 374
QXL46789.1 5.79e-269 1 374 1 374

PDB Hits      download full data without filtering help

Created with Snap18375674931121301491681872052242432612802993173363551953563QHP_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
3QHP_A 6.46e-38 195 356 2 163
Crystalstructure of the catalytic domain of cholesterol-alpha-glucosyltransferase from Helicobacter pylori [Helicobacter pylori 26695],3QHP_B Crystal structure of the catalytic domain of cholesterol-alpha-glucosyltransferase from Helicobacter pylori [Helicobacter pylori 26695]

Swiss-Prot Hits      download full data without filtering help

Created with Snap18375674931121301491681872052242432612802993173363551297sp|Q8CWR6|AMGDS_STRR6150299sp|Q59002|Y1607_METJA
Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q8CWR6 1.55e-10 1 297 1 312
Alpha-monoglucosyldiacylglycerol synthase OS=Streptococcus pneumoniae (strain ATCC BAA-255 / R6) OX=171101 GN=spr0982 PE=1 SV=1
Q59002 4.20e-07 150 299 146 314
Uncharacterized glycosyltransferase MJ1607 OS=Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) OX=243232 GN=MJ1607 PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000053 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000000008_00525.