CAZyme Information: MGYG000000049_01746

Basic Information

• Species: GCA-900066495 sp900066495
• Lineage: Bacteria; Firmicutes_A; Clostridia; Peptostreptococcales; Peptostreptococcaceae; GCA-900066495; GCA-900066495 sp900066495
• CAZyme ID: MGYG000000049_01746
• CAZy Family: CBM51
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
1474		166205.3	4.5914

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000049	3389401	Isolate	United Kingdom	Europe

• Gene Location: Start: 101375; End: 105799 Strand: +

Full Sequence      

MHKRKIAALTMAAIISNFSVRTVGVLAHELGDNKLVPNISDQNNQDIQSNQAKVSKFNLL
NSSYLEEYNKFFKLDNSKINSITNNGGNYESSVISKAIDGDFSTHWETGNSNSSSFENEV
ILTLDEVTSLNRIVYGARQDSAKGKGFAQEFEIYSSLTDDGDDFTLVSHGKYSGSTSDIV
EIKFNEEKFKRIKFKFKKANQDWASASEFMFYREDSLSDVISNMFTDGTMSELKDEYNNI
DVINNLEKEVNNHPLKDELIHDIDLAKEVLQGDKDYSDRIFTLTQYGDTHAKAKNNLQMS
TFGTDLQSTGIIAKPGEEFTIYVEAEEGAPLPSIAFTQHEGFYSNWIRQYQLKQGKNVIT
VPEIYSDSWSNKTVKGGAVYLVNKYTKEQQAKAPVVRIEGGETFPLYNLGDDKEAFIKEL
KEYNEKLEKYPENTVDVFEFNSTRLLYTGTASAAYKVYVEEGVDIGESVDNLNGQIQDAF
EFSGLKDDETDPTNDSTNVRTTIRLMQPYGLAYAYVDHIGIQRGYEQSMLRTDRDSLNSV
LWATVHEAGHQMDINAREWPEVTNNMWANSAHIKNGMGDRVSYSDLYKYLAPEDSLKGFD
DFNYFQKLGMFWQLQLKKDTYWAELETLYRERKPRPRNEQEKKDILATYSSEVLGINLTY
YFEKYGFTLSDKCKESLKQLPESKDKIWYLNSTVMDYEGSGFDGIGTGLDVSLLKSTSGT
KLSMSINENTKDDLLGYEILRNGKVIAFTTRSTYIDKDSTDDNSEYEVVPYAKDLTIGNK
VQINSLKPSISIQQEKVTLKRGEKFNPKDYVKGFTYLGEDITSKLKVESNVNTDKNGAYQ
VKYTLTNEEITVEKSLKVEVVSDYDYLSDFKWTSVNTEWGTPRRNSNIQGMVHGEVTTFK
NGIGIHANGKITYDLSDKEYDNFEALIGVDTAIGENNNSSVTFKVVADGKTVAKTNIMSY
YDNLAYINIPVSGVKELVIEVHDGGNGNTSDHCIIVNPKLTTSNGKPKFKGDESVAFNIN
EEIDLIKGISVTDGEDGDLTSKIEVESDYIKGNTGIFNVTCSVKDSDGNKAQFTRTVVVT
DKETYLSDLNWKSATIGSGYIGKDKSVRQEPIKLLNEDGYVEVFKKGIGTHAYSEIVYDS
TGYDIFDAWVGLDQFVAGQQASSVIFKVYVDGVLKAETPIMKSNTPKQHLIVDVRNSSEI
KLVVDVADSGDTWDHADWADAKFRNFSEFDLSKLEEVLEEARALDLGNYTEESAKTIKNA
IENGEKTLSSNNQTKIDTAVEEIRKAINSAVEIDLSQIIQIKDKNLKLSIQQELGLQGEV
RLGDMRELVSLTVKNVQSLEGLQYAVNLESLNIENNKIKDLSPLKDLKNLTNLKAHPQII
TEDWVLAKDKKVTVDYDVLNRNGEKLTLTSIIIKDNRTWDLTTLNVEECVDENGKISFDT
TDFYSGIHTVYMTYEDKVDNYITQITFVLDTRER

Enzyme Prediction     

No EC number prediction in MGYG000000049_01746.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
CBM51	1084	1223	1.5e-39	0.9925373134328358
CBM51	866	1000	9.6e-34	0.9850746268656716

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam08305	NPCBM	1.55e-47	1082	1224	1	136	NPCBM/NEW2 domain. This novel putative carbohydrate binding module (NPCBM) domain is found at the N-terminus of glycosyl hydrolase family 98 proteins. This domain has also been called the NEW2 domain (Naumoff DG. Phylogenetic analysis of alpha-galactosidases of the GH27 family. Molecular Biology (Engl Transl). (2004)38:388-399.)
smart00776	NPCBM	3.88e-43	1080	1224	1	145	This novel putative carbohydrate binding module (NPCBM) domain is found at the N-terminus of glycosyl hydrolase family 98 proteins.
pfam08305	NPCBM	2.91e-42	863	1001	1	136	NPCBM/NEW2 domain. This novel putative carbohydrate binding module (NPCBM) domain is found at the N-terminus of glycosyl hydrolase family 98 proteins. This domain has also been called the NEW2 domain (Naumoff DG. Phylogenetic analysis of alpha-galactosidases of the GH27 family. Molecular Biology (Engl Transl). (2004)38:388-399.)
smart00776	NPCBM	1.49e-32	866	1001	6	145	This novel putative carbohydrate binding module (NPCBM) domain is found at the N-terminus of glycosyl hydrolase family 98 proteins.
pfam13402	Peptidase_M60	1.27e-15	400	666	1	268	Peptidase M60, enhancin and enhancin-like. This family of peptidases contains a zinc metallopeptidase motif (HEXXHX(8,28)E) and possesses mucinase activity. It includes the viral enhancins as well as enhancin-like peptidases from bacterial species. Enhancins are a class of metalloproteases found in some baculoviruses that enhance viral infection by degrading the peritrophic membrane (PM) of the insect midgut. Bacterial enhancins are found to be cytotoxic when compared to viral enhancin, however, suggesting that the bacterial enhancins do not enhance infection in the same way as viral enhancin. Bacterial enhancins may have evolved a distinct biochemical function. These bacterial domains are peptidases targetting host glycoproteins and thus probably play an important role in successful colonisation of both vertebrate mucosal surfaces and the invertebrate digestive tract by both mutualistic and pathogenic microbes. This family has been augmented by a merge with the sequences in the Enhancin Pfam family.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
CEJ73532.1	0.0	47	1455	265	1675
CEK38026.1	0.0	47	1455	265	1675
AUN14245.1	0.0	47	1455	265	1675
CED93629.1	0.0	43	1472	492	1924
ABG86143.1	0.0	1	1457	1	1453

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
7JS4_A	1.19e-214	280	1228	24	980	ChainA, F5/8 type C domain protein [Clostridium perfringens ATCC 13124]
7JRM_A	1.06e-135	1002	1457	2	450	ChainA, F5/8 type C domain protein [Clostridium perfringens ATCC 13124]
7JRL_A	1.57e-135	1001	1457	23	472	ChainA, F5/8 type C domain protein [Clostridium perfringens ATCC 13124]
7JFS_A	5.54e-118	49	784	24	981	ChainA, F5/8 type C domain protein [Clostridium perfringens ATCC 13124]
5KDJ_A	4.46e-91	215	862	24	672	ZmpBmetallopeptidase from Clostridium perfringens [Clostridium perfringens ATCC 13124],5KDJ_B ZmpB metallopeptidase from Clostridium perfringens [Clostridium perfringens ATCC 13124]

Swiss-Prot Hits     

has no Swissprot hit.

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000304	0.998993	0.000195	0.000175	0.000156	0.000144

TMHMM  Annotations     

There is no transmembrane helices in MGYG000000049_01746.