Species | Kurthia massiliensis | |||||||||||
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Lineage | Bacteria; Firmicutes; Bacilli; Bacillales_A; Planococcaceae; Kurthia; Kurthia massiliensis | |||||||||||
CAZyme ID | MGYG000001406.1_00046 | |||||||||||
CAZy Family | GT2 | |||||||||||
CAZyme Description | Dimodular nonribosomal peptide synthase | |||||||||||
CAZyme Property |
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Genome Property |
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Gene Location | Start: 34831; End: 41640 Strand: - |
Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
---|---|---|---|---|---|---|---|
PRK12316 | PRK12316 | 0.0 | 418 | 1991 | 1995 | 3615 | peptide synthase; Provisional |
PRK12467 | PRK12467 | 0.0 | 979 | 2049 | 25 | 1139 | peptide synthase; Provisional |
PRK12316 | PRK12316 | 0.0 | 979 | 2022 | 25 | 1103 | peptide synthase; Provisional |
cd05930 | A_NRPS | 0.0 | 1446 | 1916 | 3 | 444 | The adenylation domain of nonribosomal peptide synthetases (NRPS). The adenylation (A) domain of NRPS recognizes a specific amino acid or hydroxy acid and activates it as an (amino) acyl adenylate by hydrolysis of ATP. The activated acyl moiety then forms a thioester bond to the enzyme-bound cofactor phosphopantetheine of a peptidyl carrier protein domain. NRPSs are large multifunctional enzymes which synthesize many therapeutically useful peptides in bacteria and fungi via a template-directed, nucleic acid independent nonribosomal mechanism. These natural products include antibiotics, immunosuppressants, plant and animal toxins, and enzyme inhibitors. NRPS has a distinct modular structure in which each module is responsible for the recognition, activation, and in some cases, modification of a single amino acid residue of the final peptide product. The modules can be subdivided into domains that catalyze specific biochemical reactions. |
PRK12467 | PRK12467 | 0.0 | 1005 | 2146 | 2648 | 3818 | peptide synthase; Provisional |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
---|---|---|---|---|---|
QND46664.1 | 2.30e-247 | 440 | 2115 | 1023 | 2780 |
ACX49739.1 | 1.60e-154 | 4 | 1642 | 12 | 1793 |
BAY30132.1 | 9.70e-154 | 918 | 2117 | 2149 | 3413 |
BAY90071.1 | 2.17e-152 | 873 | 2117 | 2081 | 3402 |
BAZ75991.1 | 2.78e-151 | 918 | 2117 | 2147 | 3411 |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
---|---|---|---|---|---|---|
6MFZ_A | 1.08e-216 | 434 | 2000 | 213 | 1799 | Crystalstructure of dimodular LgrA in a condensation state [Brevibacillus parabrevis],6MFZ_B Crystal structure of dimodular LgrA in a condensation state [Brevibacillus parabrevis] |
6MFY_A | 2.48e-204 | 434 | 1919 | 213 | 1715 | Crystalstructure of a 5-domain construct of LgrA in the substrate donation state [Brevibacillus parabrevis],6MG0_A Crystal structure of a 5-domain construct of LgrA in the thiolation state [Brevibacillus parabrevis],6MG0_B Crystal structure of a 5-domain construct of LgrA in the thiolation state [Brevibacillus parabrevis] |
5U89_A | 1.07e-186 | 425 | 1358 | 23 | 1005 | Crystalstructure of a cross-module fragment from the dimodular NRPS DhbF [Geobacillus sp. Y4.1MC1] |
4ZXH_A | 1.06e-130 | 1006 | 2117 | 19 | 1162 | ChainA, ABBFA_003403 [Acinetobacter baumannii AB307-0294],4ZXI_A Chain A, Tyrocidine synthetase 3 [Acinetobacter baumannii AB307-0294] |
6N8E_A | 1.50e-130 | 1004 | 2055 | 30 | 1128 | Crystalstructure of holo-ObiF1, a five domain nonribosomal peptide synthetase from Burkholderia diffusa [Burkholderia diffusa] |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
---|---|---|---|---|---|---|
P45745 | 0.0 | 4 | 2265 | 11 | 2378 | Dimodular nonribosomal peptide synthase OS=Bacillus subtilis (strain 168) OX=224308 GN=dhbF PE=1 SV=4 |
P39846 | 3.35e-263 | 277 | 1998 | 300 | 2076 | Plipastatin synthase subunit B OS=Bacillus subtilis (strain 168) OX=224308 GN=ppsB PE=1 SV=1 |
O30409 | 2.18e-252 | 7 | 2120 | 4171 | 6344 | Tyrocidine synthase 3 OS=Brevibacillus parabrevis OX=54914 GN=tycC PE=1 SV=1 |
P0C064 | 6.23e-246 | 4 | 2134 | 2099 | 4310 | Gramicidin S synthase 2 OS=Brevibacillus brevis OX=1393 GN=grsB PE=1 SV=2 |
Q70LM6 | 3.25e-245 | 120 | 2015 | 2712 | 4692 | Linear gramicidin synthase subunit B OS=Brevibacillus parabrevis OX=54914 GN=lgrB PE=1 SV=1 |
Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
---|---|---|---|---|---|
1.000031 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |
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