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CAZyme Information: MGYG000001809_02239
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Eisenbergiella; | |||||||||||
| CAZyme ID | MGYG000001809_02239 | |||||||||||
| CAZy Family | GT11 | |||||||||||
| CAZyme Description | O-antigen biosynthesis glycosyltransferase WbnK | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 32734; End: 33600 Strand: - | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT11 | 1 | 283 | 1e-70 | 0.9818840579710145 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| cd11301 | Fut1_Fut2_like | 7.06e-73 | 1 | 272 | 1 | 257 | Alpha-1,2-fucosyltransferase. Alpha-1,2-fucosyltransferases (Fut1, Fut2) catalyze the transfer of alpha-L-fucose to the terminal beta-D-galactose residue of glycoconjugates via an alpha-1,2-linkage, generating carbohydrate structures that exhibit H-antigenicity for blood-group carbohydrates. These structures also act as ligands for morphogenesis, the adhesion of microbes, and metastasizing cancer cells. Fut1 is responsible for producing the H antigen on red blood cells. Fut2 is expressed in epithelia of secretory tissues, and individuals termed "secretors" have at least one functional copy of the gene; they secrete H antigen which is further processed into A and/or B antigens depending on the ABO genotype. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. |
| pfam01531 | Glyco_transf_11 | 3.25e-30 | 1 | 267 | 32 | 276 | Glycosyl transferase family 11. This family contains several fucosyl transferase enzymes. |
| cd11548 | NodZ_like | 1.28e-05 | 1 | 260 | 1 | 284 | Alpha 1,6-fucosyltransferase similar to Bradyrhizobium NodZ. Bradyrhizobium NodZ is an alpha 1,6-fucosyltransferase involved in the biosynthesis of the nodulation factor, a lipo-chitooligosaccharide formed by three-to-six beta-1,4-linked N-acetyl-d-glucosamine (GlcNAc) residues and a fatty acid acyl group attached to the nitrogen atom at the non-reducing end. NodZ transfers L-fucose from the GDP-beta-L-fucose donor to the reducing residue of the chitin oligosaccharide backbone, before the attachment of a fatty acid group. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| ADL35260.1 | 3.74e-81 | 1 | 287 | 1 | 288 |
| AOZ97425.1 | 1.72e-79 | 1 | 287 | 1 | 288 |
| SNX52916.1 | 4.23e-63 | 1 | 287 | 1 | 287 |
| QUO20851.1 | 3.18e-62 | 1 | 269 | 1 | 264 |
| QCT75971.1 | 4.27e-56 | 1 | 272 | 1 | 266 |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| Q58YV9 | 4.18e-30 | 6 | 287 | 5 | 302 | O-antigen biosynthesis glycosyltransferase WbnK OS=Escherichia coli OX=562 GN=wbnK PE=1 SV=1 |
| Q10980 | 1.86e-10 | 109 | 258 | 165 | 320 | Galactoside alpha-(1,2)-fucosyltransferase 1 OS=Rattus norvegicus OX=10116 GN=Fut1 PE=2 SV=2 |
| O09160 | 4.54e-10 | 109 | 258 | 166 | 321 | Galactoside alpha-(1,2)-fucosyltransferase 1 OS=Mus musculus OX=10090 GN=Fut1 PE=1 SV=2 |
| Q866E8 | 7.93e-10 | 109 | 258 | 165 | 320 | Galactoside alpha-(1,2)-fucosyltransferase 1 OS=Sapajus apella OX=9515 GN=FUT1 PE=3 SV=1 |
| Q866C7 | 1.92e-09 | 109 | 258 | 165 | 320 | Galactoside alpha-(1,2)-fucosyltransferase 1 OS=Ateles belzebuth OX=9507 GN=FUT1 PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000053 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |