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CAZyme Information: MGYG000001963_00378
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Phocaeicola sp000434735 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Phocaeicola; Phocaeicola sp000434735 | |||||||||||
| CAZyme ID | MGYG000001963_00378 | |||||||||||
| CAZy Family | PL13 | |||||||||||
| CAZyme Description | Heparin lyase I | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 26202; End: 27389 Strand: - | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| PL13 | 44 | 395 | 3.1e-161 | 0.977961432506887 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| pfam14099 | Polysacc_lyase | 3.05e-15 | 69 | 385 | 9 | 201 | Polysaccharide lyase. This family includes heparin lyase I, EC:4.2.2.7. Heparin lyase I depolymerizes heparin by cleaving the glycosidic linkage next to an iduronic acid moiety. The structure of heparin lyase I consists of a beta-jelly roll domain with a long, deep substrate-binding groove and an unusual thumb domain containing many basic residues extending from the main body of the enzyme. This family also includes glucuronan lyase, EC:4.2.2.14. The structure glucuronan lyase is a beta-jelly roll. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QUT44448.1 | 1.74e-147 | 44 | 394 | 27 | 391 |
| ADL62736.1 | 2.31e-147 | 44 | 391 | 27 | 388 |
| CBK62841.1 | 2.86e-147 | 39 | 395 | 17 | 374 |
| QRQ49642.1 | 1.00e-146 | 44 | 394 | 27 | 391 |
| QQA07236.1 | 1.32e-146 | 46 | 395 | 27 | 390 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 3IMN_A | 2.98e-148 | 46 | 395 | 11 | 374 | Crystalstructure of heparin lyase I from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron],3IN9_A Crystal structure of heparin lyase I complexed with disaccharide heparin [Bacteroides thetaiotaomicron] |
| 3ILR_A | 4.55e-148 | 46 | 395 | 5 | 368 | Structureof Heparinase I from Bacteroides thetaiotaomicron in complex with tetrasaccharide product [Bacteroides thetaiotaomicron] |
| 3IKW_A | 5.22e-148 | 46 | 395 | 9 | 372 | Structureof Heparinase I from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron] |
| 3INA_A | 9.81e-147 | 46 | 395 | 11 | 374 | Crystalstructure of heparin lyase I H151A mutant complexed with a dodecasaccharide heparin [Bacteroides thetaiotaomicron] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| Q05819 | 3.08e-144 | 47 | 395 | 28 | 380 | Heparin lyase I OS=Pedobacter heparinus OX=984 PE=1 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as LIPO
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.000525 | 0.339277 | 0.659471 | 0.000281 | 0.000244 | 0.000188 |