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CAZyme Information: MGYG000002321_00657

You are here: Home > Sequence: MGYG000002321_00657

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Ruminococcus_D bicirculans
Lineage Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Ruminococcaceae; Ruminococcus_D; Ruminococcus_D bicirculans
CAZyme ID MGYG000002321_00657
CAZy Family GH5
CAZyme Description hypothetical protein
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
639 69043.97 6.7847
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000002321 2968500 Isolate not provided not provided
Gene Location Start: 713242;  End: 715161  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

EC 3.2.1.78

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH5 49 295 2.3e-97 0.9881422924901185
CBM65 521 635 1.1e-27 0.9649122807017544
CBM13 356 453 1.4e-18 0.4946808510638298

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
pfam00150 Cellulase 2.48e-36 48 292 1 272
Cellulase (glycosyl hydrolase family 5).
pfam18259 CBM65_1 6.13e-25 522 635 1 113
Carbohydrate binding module 65 domain 1. This domain is found in the non-catalytic carbohydrate binding module 65B (CMB65B) present in Eubacterium cellulosolvens. CBMs are present in plant cell wall degrading enzymes and are responsible for targeting, which enhances catalysis. CBM65s display higher affinity for oligosaccharides, such as cellohexaose, and particularly polysaccharides than cellotetraose, which fully occupies the core component of the substrate binding cleft. The concave surface presented by beta-sheet 2 comprises the beta-glucan binding site in CBM65s. C6 of all the backbone glucose moieties makes extensive hydrophobic interactions with the surface tryptophans of CBM65s. Three out of the four surface Trp are highly conserved. The conserved metal ion site typical of CBMs is absent in this CBM65 family.
pfam14200 RicinB_lectin_2 2.34e-19 359 438 12 89
Ricin-type beta-trefoil lectin domain-like.
pfam14200 RicinB_lectin_2 3.28e-18 395 486 1 89
Ricin-type beta-trefoil lectin domain-like.
pfam00652 Ricin_B_lectin 7.10e-08 361 496 2 126
Ricin-type beta-trefoil lectin domain.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
CCO04360.1 0.0 1 639 1 639
ADU21877.1 2.78e-207 4 639 3 485
ADU23074.1 3.50e-151 20 335 15 331
BAA25878.1 3.97e-137 31 335 29 333
BAD99527.1 6.84e-137 31 338 27 334

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
1WKY_A 3.39e-137 34 338 4 308
Crystalstructure of alkaline mannanase from Bacillus sp. strain JAMB-602: catalytic domain and its Carbohydrate Binding Module [Bacillus sp. JAMB-602]
3JUG_A 1.33e-123 27 336 12 321
Crystalstructure of endo-beta-1,4-mannanase from the alkaliphilic Bacillus sp. N16-5 [Bacillus sp. N16-5]
2WHJ_A 6.67e-122 38 333 1 296
Understandinghow diverse mannanases recognise heterogeneous substrates [Salipaludibacillus agaradhaerens]
2WHL_A 1.86e-117 39 333 1 293
Understandinghow diverse mannanases recognise heterogeneous substrates [Salipaludibacillus agaradhaerens]
1BQC_A 1.69e-79 37 333 1 301
Beta-MannanaseFrom Thermomonospora Fusca [Thermobifida fusca],2MAN_A Mannotriose Complex Of Thermomonospora Fusca Beta-Mannanase [Thermobifida fusca],3MAN_A Mannohexaose Complex Of Thermomonospora Fusca Beta-mannanase [Thermobifida fusca]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
G1K3N4 3.65e-121 38 333 1 296
Mannan endo-1,4-beta-mannosidase OS=Salipaludibacillus agaradhaerens OX=76935 PE=1 SV=1
P51529 2.43e-89 10 339 6 341
Mannan endo-1,4-beta-mannosidase OS=Streptomyces lividans OX=1916 GN=manA PE=1 SV=2
B3PF24 1.56e-82 23 340 33 352
Mannan endo-1,4-beta-mannosidase OS=Cellvibrio japonicus (strain Ueda107) OX=498211 GN=man5A PE=1 SV=1
P22533 3.48e-60 59 313 55 313
Beta-mannanase/endoglucanase A OS=Caldicellulosiruptor saccharolyticus OX=44001 GN=manA PE=1 SV=2
P07983 7.10e-10 19 287 13 292
Endoglucanase OS=Bacillus subtilis OX=1423 GN=bglC PE=3 SV=2

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000284 0.998958 0.000204 0.000187 0.000167 0.000153

TMHMM  Annotations      download full data without filtering help

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12 34