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CAZyme Information: MGYG000002365_01649

You are here: Home > Sequence: MGYG000002365_01649

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Bifidobacterium globosum
Lineage Bacteria; Actinobacteriota; Actinomycetia; Actinomycetales; Bifidobacteriaceae; Bifidobacterium; Bifidobacterium globosum
CAZyme ID MGYG000002365_01649
CAZy Family GT39
CAZyme Description putative dolichyl-phosphate-mannose--protein mannosyltransferase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
533 60028.18 9.225
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000002365 2036949 Isolate Kenya Africa
Gene Location Start: 1903460;  End: 1905061  Strand: +

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000002365_01649.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GT39 45 316 4.3e-65 0.9910313901345291

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
COG1928 PMT1 4.29e-19 342 533 498 694
Dolichyl-phosphate-mannose--protein O-mannosyl transferase [Posttranslational modification, protein turnover, chaperones].
pfam16192 PMT_4TMC 6.69e-15 343 530 1 198
C-terminal four TMM region of protein-O-mannosyltransferase. PMT_4TMC is the C-terminal four membrane-pass region of protein-O-mannosyltransferases and similar enzymes.
pfam02366 PMT 2.37e-06 44 274 2 201
Dolichyl-phosphate-mannose-protein mannosyltransferase. This is a family of Dolichyl-phosphate-mannose-protein mannosyltransferase proteins EC:2.4.1.109. These proteins are responsible for O-linked glycosylation of proteins, they catalyze the reaction:- Dolichyl phosphate D-mannose + protein <=> dolichyl phosphate + O-D-mannosyl-protein. Also in this family is Drosophila rotated abdomen protein which is a putative mannosyltransferase. This family appears to be distantly related to pfam02516 (A Bateman pers. obs.). This family also contains sequences from ArnTs (4-amino-4-deoxy-L-arabinose lipid A transferase). They catalyze the addition of 4-amino-4-deoxy-l-arabinose (l-Ara4N) to the lipid A moiety of the lipopolysaccharide. This is a critical modification enabling bacteria (e.g. Escherichia coli and Salmonella typhimurium) to resist killing by antimicrobial peptides such as polymyxins. Members such as undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase are predicted to have 12 trans-membrane regions. The N-terminal portion of these proteins is hypothesized to have a conserved glycosylation activity which is shared between distantly related oligosaccharyltransferases ArnT and PglB families.
pfam13231 PMT_2 1.99e-05 119 287 1 140
Dolichyl-phosphate-mannose-protein mannosyltransferase. This family contains members that are not captured by pfam02366.
COG4346 COG4346 2.90e-05 120 469 136 399
Predicted membrane-bound dolichyl-phosphate-mannose-protein mannosyltransferase [Posttranslational modification, protein turnover, chaperones].

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
AIZ16884.1 0.0 1 533 1 533
ASW24379.1 0.0 1 533 1 533
ATO40593.1 0.0 37 533 1 497
ATU21128.1 2.53e-295 42 533 2 495
ADG34083.1 1.09e-283 35 533 35 537

PDB Hits      help

has no PDB hit.

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
L8F4Z2 1.85e-68 35 532 34 515
Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycolicibacterium smegmatis (strain MKD8) OX=1214915 GN=pmt PE=3 SV=1
P9WN04 3.37e-65 39 532 44 521
Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) OX=83331 GN=pmt PE=3 SV=2
P9WN05 3.37e-65 39 532 44 521
Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=pmt PE=1 SV=2
Q8NRZ6 9.88e-49 44 532 40 519
Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) OX=196627 GN=pmt PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.999634 0.000381 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      download full data without filtering help

start end
141 163
170 189
194 213
234 253
257 274
294 316
411 430
437 454
459 481
493 515