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CAZyme Information: MGYG000002428_00244

You are here: Home > Sequence: MGYG000002428_00244

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Campylobacter_A concisus_W
Lineage Bacteria; Campylobacterota; Campylobacteria; Campylobacterales; Campylobacteraceae; Campylobacter_A; Campylobacter_A concisus_W
CAZyme ID MGYG000002428_00244
CAZy Family GT19
CAZyme Description Lipid-A-disaccharide synthase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
344 38538.19 8.9103
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000002428 1937734 Isolate South Africa Africa
Gene Location Start: 244983;  End: 246017  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

EC 2.4.1.182

CAZyme Signature Domains help

Family Start End Evalue family coverage
GT19 3 314 2.6e-90 0.9378531073446328

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
PRK14089 PRK14089 0.0 1 343 2 347
lipid-A-disaccharide synthase.
COG0763 LpxB 9.52e-104 1 333 2 367
Lipid A disaccharide synthetase [Cell wall/membrane/envelope biogenesis].
pfam02684 LpxB 5.16e-85 3 332 1 369
Lipid-A-disaccharide synthetase. This is a family of lipid-A-disaccharide synthetases, EC:2.4.2.128. These enzymes catalyze the reaction: UDP-2,3-bis(3-hydroxytetradecanoyl) glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate <=> UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6 -beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate. These enzymes catalyze the fist disaccharide step in the synthesis of lipid-A-disaccharide.
PRK00025 lpxB 5.97e-81 1 339 2 370
lipid-A-disaccharide synthase; Reviewed
TIGR00215 lpxB 2.49e-75 3 334 8 377
lipid-A-disaccharide synthase. Lipid-A precursor biosynthesis producing lipid A disaccharide in a condensation reaction. transcribed as part of an operon including lpxA [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
QPI05286.1 5.10e-241 1 344 1 344
QPH93352.1 1.03e-240 1 344 1 344
QPI01654.1 4.19e-240 1 344 1 344
QPH99862.1 4.19e-240 1 344 1 344
QPH84958.1 1.71e-239 1 344 1 344

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
5W8N_A 1.75e-22 77 308 92 340
LipidA Disaccharide Synthase (LpxB)-6 solubilizing mutations [Escherichia coli BL21(DE3)]
5W8S_A 1.75e-22 77 308 92 340
LipidA Disaccharide Synthase (LpxB)-7 solubilizing mutations [Escherichia coli BL21(DE3)],5W8X_A Lipid A Disaccharide Synthase (LpxB)-7 solubilizing mutations-Bound to UDP [Escherichia coli BL21(DE3)]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
A8FK76 3.94e-134 4 343 5 364
Lipid-A-disaccharide synthase OS=Campylobacter jejuni subsp. jejuni serotype O:6 (strain 81116 / NCTC 11828) OX=407148 GN=lpxB PE=3 SV=1
Q5HWH9 3.94e-134 4 343 5 364
Lipid-A-disaccharide synthase OS=Campylobacter jejuni (strain RM1221) OX=195099 GN=lpxB PE=3 SV=1
Q9PIK8 7.92e-134 4 343 5 364
Lipid-A-disaccharide synthase OS=Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168) OX=192222 GN=lpxB PE=3 SV=1
Q17WJ2 4.60e-99 3 336 4 349
Lipid-A-disaccharide synthase OS=Helicobacter acinonychis (strain Sheeba) OX=382638 GN=lpxB PE=3 SV=1
O25537 6.80e-96 3 336 4 349
Lipid-A-disaccharide synthase OS=Helicobacter pylori (strain ATCC 700392 / 26695) OX=85962 GN=lpxB PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000081 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000002428_00244.