You are browsing environment: HUMAN GUT
CAZyme Information: MGYG000002507_04535
You are here: Home > Sequence: MGYG000002507_04535
Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Escherichia albertii | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia; Escherichia albertii | |||||||||||
| CAZyme ID | MGYG000002507_04535 | |||||||||||
| CAZy Family | GT44 | |||||||||||
| CAZyme Description | hypothetical protein | |||||||||||
| CAZyme Property |
|
|||||||||||
| Genome Property |
|
|||||||||||
| Gene Location | Start: 931; End: 8700 Strand: - | |||||||||||
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| NF033479 | Efa1_rel_toxin | 0.0 | 30 | 2514 | 13 | 2560 | LifA/Efa1-related large cytotoxin. Members of this family are large and almost certainly multifunctional proteins found in various pathogens from genus Chlamydia, about 3000 amino acids in size and related to lymphostatin (Efa1/LifA) from enteropathogenic Escherichia coli. Roles have been suggested for Efa1 (EHEC factor for adherence) in adhesion, so some members have been annotated as adherence proteins rather than cytotoxins. |
| pfam12919 | TcdA_TcdB | 4.45e-41 | 258 | 681 | 1 | 382 | TcdA/TcdB catalytic glycosyltransferase domain. This domain represents the N-terminal glycosyltransferase from a set of toxins found in some bacteria. This domain in TcdB glycosylates the host RhoA protein. |
| cd20495 | C58_PaToxP-like | 1.30e-27 | 1393 | 1568 | 1 | 168 | peptidase C58 domain of Photorhabdus asymbiotica toxin PaTox and LifA/Efa1-related large cytotoxin, and similar proteins. This subfamily includes the cysteine protease domain of Photorhabdus asymbiotica toxin PaTox, a large virulence-associated multifunctional protein toxin. This domain is similar to AvrPphB protease found in Pseudomonas syringae, a C58 protease. Mutation studies show that this domain enhances cytotoxic effects of the toxin, and therefore is essential for full PaTox activity. Also included in this family is the enteropathogenic Escherichia coli (EPEC) factor for adherence/lymphocyte activation inhibitor (efa1/lifA) gene which is strongly associated with diarrhea. Efa1/LifA proteins are important for A/E lesion formation efficiency in EPEC strains lacking multiple effectors. This domain contains the invariant C/H/D residues conserved in the C58/YopT family. |
| pfam11996 | DUF3491 | 4.09e-14 | 2133 | 2512 | 13 | 391 | Protein of unknown function (DUF3491). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 286 to 3225 amino acids in length. This protein is found associated with pfam04488. This protein is found associated with pfam04488. |
| pfam04488 | Gly_transf_sug | 1.05e-05 | 452 | 482 | 49 | 79 | Glycosyltransferase sugar-binding region containing DXD motif. The DXD motif is a short conserved motif found in many families of glycosyltransferases, which add a range of different sugars to other sugars, phosphates and proteins. DXD-containing glycosyltransferases all use nucleoside diphosphate sugars as donors and require divalent cations, usually manganese. The DXD motif is expected to play a carbohydrate binding role in sugar-nucleoside diphosphate and manganese dependent glycosyltransferases. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QST49069.1 | 0.0 | 1 | 2589 | 1 | 2589 |
| QTA28835.1 | 0.0 | 1 | 2583 | 1 | 2597 |
| AMG08231.1 | 0.0 | 28 | 2585 | 30 | 2972 |
| AVF62353.1 | 0.0 | 28 | 2585 | 30 | 2976 |
| AMG29389.2 | 0.0 | 133 | 2583 | 25 | 2870 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 3SRZ_A | 5.11e-16 | 191 | 696 | 28 | 482 | ChainA, Toxin A [Clostridioides difficile 630],3SS1_A Chain A, Toxin A [Clostridioides difficile 630] |
| 4DMV_A | 5.12e-16 | 191 | 696 | 43 | 497 | ChainA, Toxin A [Clostridioides difficile],4DMW_A Chain A, Toxin A [Clostridioides difficile] |
| 5UQK_A | 5.16e-16 | 191 | 696 | 28 | 482 | ChainA, Toxin A [Clostridioides difficile],5UQL_A Chain A, Toxin A [Clostridioides difficile] |
| 7POG_A | 7.65e-16 | 191 | 696 | 28 | 482 | ChainA, Toxin A [Clostridioides difficile] |
| 7U2P_A | 8.53e-16 | 191 | 696 | 29 | 483 | ChainA, Glucosyltransferase TcdA [Clostridioides difficile] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P16154 | 7.17e-15 | 191 | 696 | 28 | 482 | Toxin A OS=Clostridioides difficile OX=1496 GN=tcdA PE=1 SV=2 |
| P18177 | 3.52e-14 | 193 | 693 | 43 | 480 | Toxin B OS=Clostridioides difficile OX=1496 GN=tcdB PE=1 SV=3 |
| Q46149 | 5.93e-14 | 196 | 734 | 46 | 535 | Toxin A OS=Clostridium novyi OX=1542 GN=tcdA PE=1 SV=1 |
| P0DUB4 | 3.95e-13 | 193 | 609 | 31 | 443 | Cytotoxin-L OS=Paeniclostridium sordellii OX=1505 GN=tcsL PE=1 SV=1 |
| Q46342 | 1.16e-12 | 193 | 494 | 31 | 303 | Cytotoxin-L OS=Paeniclostridium sordellii OX=1505 GN=tcsL PE=1 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000035 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |