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CAZyme Information: MGYG000003123_02533
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Chimaeribacter coloradensis | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Chimaeribacter; Chimaeribacter coloradensis | |||||||||||
| CAZyme ID | MGYG000003123_02533 | |||||||||||
| CAZy Family | GH20 | |||||||||||
| CAZyme Description | Chitobiase | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 13; End: 837 Strand: + | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH20 | 1 | 152 | 1.3e-26 | 0.3590504451038576 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| cd06569 | GH20_Sm-chitobiase-like | 2.95e-80 | 1 | 188 | 257 | 443 | The chitobiase of Serratia marcescens is a beta-N-1,4-acetylhexosaminidase with a glycosyl hydrolase family 20 (GH20) domain that hydrolyzes the beta-1,4-glycosidic linkages in oligomers derived from chitin. Chitin is degraded by a two step process: i) a chitinase hydrolyzes the chitin to oligosaccharides and disaccharides such as di-N-acetyl-D-glucosamine and chitobiose, ii) chitobiase then further degrades these oligomers into monomers. The GH20 hexosaminidases are thought to act via a catalytic mechanism in which the catalytic nucleophile is not provided by solvent or the enzyme, but by the substrate itself. |
| COG3525 | Chb | 3.30e-40 | 1 | 268 | 483 | 730 | N-acetyl-beta-hexosaminidase [Carbohydrate transport and metabolism]. |
| pfam03174 | CHB_HEX_C | 6.03e-32 | 194 | 269 | 1 | 76 | Chitobiase/beta-hexosaminidase C-terminal domain. This short domain represents the C terminal domain in chitobiases and beta-hexosaminidases EC:3.2.1.52. It is composed of a beta sandwich structure. The function of this domain is unknown. |
| pfam00728 | Glyco_hydro_20 | 9.01e-27 | 1 | 152 | 216 | 344 | Glycosyl hydrolase family 20, catalytic domain. This domain has a TIM barrel fold. |
| cd02742 | GH20_hexosaminidase | 7.02e-26 | 1 | 152 | 187 | 303 | Beta-N-acetylhexosaminidases of glycosyl hydrolase family 20 (GH20) catalyze the removal of beta-1,4-linked N-acetyl-D-hexosamine residues from the non-reducing ends of N-acetyl-beta-D-hexosaminides including N-acetylglucosides and N-acetylgalactosides. These enzymes are broadly distributed in microorganisms, plants and animals, and play roles in various key physiological and pathological processes. These processes include cell structural integrity, energy storage, cellular signaling, fertilization, pathogen defense, viral penetration, the development of carcinomas, inflammatory events and lysosomal storage disorders. The GH20 enzymes include the eukaryotic beta-N-acetylhexosaminidases A and B, the bacterial chitobiases, dispersin B, and lacto-N-biosidase. The GH20 hexosaminidases are thought to act via a catalytic mechanism in which the catalytic nucleophile is not provided by the solvent or the enzyme, but by the substrate itself. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QCR36772.1 | 7.99e-174 | 1 | 274 | 613 | 886 |
| AJJ84064.1 | 3.56e-143 | 1 | 274 | 413 | 687 |
| AKS79444.1 | 2.86e-142 | 1 | 274 | 413 | 687 |
| AKS58646.1 | 2.86e-142 | 1 | 274 | 413 | 687 |
| AJJ30250.1 | 2.86e-142 | 1 | 274 | 413 | 687 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 1C7S_A | 1.63e-134 | 1 | 272 | 586 | 858 | ChainA, BETA-N-ACETYLHEXOSAMINIDASE [Serratia marcescens] |
| 1C7T_A | 1.63e-134 | 1 | 272 | 586 | 858 | ChainA, BETA-N-ACETYLHEXOSAMINIDASE [Serratia marcescens] |
| 1QBA_A | 1.63e-134 | 1 | 272 | 586 | 858 | BACTERIALCHITOBIASE, GLYCOSYL HYDROLASE FAMILY 20 [Serratia marcescens],1QBB_A BACTERIAL CHITOBIASE COMPLEXED WITH CHITOBIOSE (DINAG) [Serratia marcescens] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| Q54468 | 3.42e-133 | 1 | 272 | 613 | 885 | Chitobiase OS=Serratia marcescens OX=615 GN=chb PE=1 SV=1 |
| P13670 | 5.72e-102 | 2 | 272 | 613 | 882 | N,N'-diacetylchitobiase OS=Vibrio harveyi OX=669 GN=chb PE=1 SV=1 |
| Q04786 | 1.40e-65 | 3 | 272 | 568 | 844 | Beta-hexosaminidase OS=Vibrio vulnificus OX=672 GN=hex PE=3 SV=1 |
| P49007 | 1.28e-35 | 4 | 191 | 577 | 768 | Beta-hexosaminidase B OS=Pseudoalteromonas piscicida OX=43662 GN=nag096 PE=3 SV=1 |
| P86956 | 1.13e-13 | 42 | 274 | 659 | 902 | Putative beta-hexosaminidase OS=Pinctada maxima OX=104660 PE=1 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000075 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |