Species | UBA5416 sp900539175 | |||||||||||
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Lineage | Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; UBA5416; UBA5416 sp900539175 | |||||||||||
CAZyme ID | MGYG000003192_00498 | |||||||||||
CAZy Family | GT2 | |||||||||||
CAZyme Description | D-alanine--poly(phosphoribitol) ligase subunit 1 | |||||||||||
CAZyme Property |
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Genome Property |
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Gene Location | Start: 18287; End: 25711 Strand: + |
Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
---|---|---|---|---|---|---|---|
cd05930 | A_NRPS | 0.0 | 1713 | 2186 | 1 | 444 | The adenylation domain of nonribosomal peptide synthetases (NRPS). The adenylation (A) domain of NRPS recognizes a specific amino acid or hydroxy acid and activates it as an (amino) acyl adenylate by hydrolysis of ATP. The activated acyl moiety then forms a thioester bond to the enzyme-bound cofactor phosphopantetheine of a peptidyl carrier protein domain. NRPSs are large multifunctional enzymes which synthesize many therapeutically useful peptides in bacteria and fungi via a template-directed, nucleic acid independent nonribosomal mechanism. These natural products include antibiotics, immunosuppressants, plant and animal toxins, and enzyme inhibitors. NRPS has a distinct modular structure in which each module is responsible for the recognition, activation, and in some cases, modification of a single amino acid residue of the final peptide product. The modules can be subdivided into domains that catalyze specific biochemical reactions. |
PRK12316 | PRK12316 | 0.0 | 1258 | 2268 | 51 | 1081 | peptide synthase; Provisional |
PRK12316 | PRK12316 | 0.0 | 1135 | 2268 | 2482 | 3619 | peptide synthase; Provisional |
PRK12467 | PRK12467 | 0.0 | 1240 | 2284 | 29 | 1110 | peptide synthase; Provisional |
PRK12467 | PRK12467 | 0.0 | 1167 | 2268 | 1029 | 2160 | peptide synthase; Provisional |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
---|---|---|---|---|---|
BAY90071.1 | 4.40e-231 | 41 | 2273 | 1212 | 3285 |
BAY30132.1 | 9.52e-230 | 41 | 2273 | 1215 | 3296 |
BAZ00088.1 | 1.03e-225 | 41 | 2273 | 1213 | 3294 |
BAZ75991.1 | 1.03e-225 | 41 | 2273 | 1213 | 3294 |
QND46664.1 | 9.31e-169 | 1159 | 2281 | 1515 | 2674 |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
---|---|---|---|---|---|---|
6MFZ_A | 3.48e-179 | 1168 | 2271 | 700 | 1797 | Crystalstructure of dimodular LgrA in a condensation state [Brevibacillus parabrevis],6MFZ_B Crystal structure of dimodular LgrA in a condensation state [Brevibacillus parabrevis] |
6P1J_A | 3.81e-168 | 1257 | 2186 | 6 | 964 | Thestructure of condensation and adenylation domains of teixobactin-producing nonribosomal peptide synthetase Txo2 serine module [Eleftheria terrae],6P1J_B The structure of condensation and adenylation domains of teixobactin-producing nonribosomal peptide synthetase Txo2 serine module [Eleftheria terrae] |
6MFY_A | 1.71e-166 | 1168 | 2186 | 700 | 1712 | Crystalstructure of a 5-domain construct of LgrA in the substrate donation state [Brevibacillus parabrevis],6MG0_A Crystal structure of a 5-domain construct of LgrA in the thiolation state [Brevibacillus parabrevis],6MG0_B Crystal structure of a 5-domain construct of LgrA in the thiolation state [Brevibacillus parabrevis] |
6OYF_A | 6.69e-148 | 1258 | 2101 | 4 | 873 | Thestructure of condensation and adenylation domains of teixobactin-producing nonribosomal peptide synthetase Txo1 serine module [Eleftheria terrae],6OZV_A The structure of condensation and adenylation domains of teixobactin-producing nonribosomal peptide synthetase Txo1 serine module in complex with AMP [Eleftheria terrae],6P4U_A The structure of condensation and adenylation domains of teixobactin-producing nonribosomal peptide synthetase Txo1 serine module in complex with Mg and AMP [Eleftheria terrae] |
6P3I_A | 5.05e-142 | 1258 | 2101 | 4 | 873 | Thestructure of condensation and adenylation domains of teixobactin-producing nonribosomal peptide synthetase Txo1 serine module in complex with Mg [Eleftheria terrae] |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
---|---|---|---|---|---|---|
Q9R9J1 | 8.20e-248 | 41 | 2378 | 671 | 3629 | Mycosubtilin synthase subunit A OS=Bacillus subtilis OX=1423 GN=mycA PE=1 SV=1 |
P94459 | 4.29e-218 | 1170 | 2291 | 972 | 2088 | Plipastatin synthase subunit D OS=Bacillus subtilis (strain 168) OX=224308 GN=ppsD PE=1 SV=2 |
O30409 | 3.17e-202 | 1168 | 2291 | 969 | 2093 | Tyrocidine synthase 3 OS=Brevibacillus parabrevis OX=54914 GN=tycC PE=1 SV=1 |
P0C064 | 3.23e-200 | 1167 | 2284 | 3054 | 4173 | Gramicidin S synthase 2 OS=Brevibacillus brevis OX=1393 GN=grsB PE=1 SV=2 |
P0C063 | 7.74e-199 | 1167 | 2284 | 3055 | 4174 | Gramicidin S synthase 2 OS=Aneurinibacillus migulanus OX=47500 GN=grsB PE=3 SV=2 |
Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
---|---|---|---|---|---|
1.000043 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |
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