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CAZyme Information: MGYG000003397.1_01312

You are here: Home > Sequence: MGYG000003397.1_01312

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species F0422 sp900766245
Lineage Bacteria; Firmicutes_C; Negativicutes; Veillonellales; Veillonellaceae; F0422; F0422 sp900766245
CAZyme ID MGYG000003397.1_01312
CAZy Family GH23
CAZyme Description Soluble lytic murein transglycosylase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
187 MGYG000003397.1_29|CGC1 21477.27 4.6547
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000003397.1 1814704 MAG United States North America
Gene Location Start: 31586;  End: 32149  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000003397.1_01312.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH23 41 180 2.1e-32 0.8814814814814815

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd16896 LT_Slt70-like 3.88e-78 33 175 1 143
uncharacterized lytic transglycosylase subfamily with similarity to Slt70. Uncharacterized lytic transglycosylase (LT) with a conserved sequence pattern suggesting similarity to the Slt70, a 70kda soluble lytic transglycosylase which also has an N-terminal U-shaped U-domain and a linker L-domain. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue.
cd13401 Slt70-like 6.57e-61 31 182 1 152
70kDa soluble lytic transglycosylase (Slt70) and similar proteins. Catalytic domain of the 70kda soluble lytic transglycosylase (LT)-like proteins, which also have an N-terminal U-shaped U-domain and a linker L-domain. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. Proteins similar to this family include the soluble and insoluble membrane-bound LTs in bacteria and the LTs in bacteriophage lambda.
cd00254 LT-like 1.08e-38 51 175 1 109
lytic transglycosylase(LT)-like domain. Members include the soluble and insoluble membrane-bound LTs in bacteria and LTs in bacteriophage lambda. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue.
COG0741 MltE 2.18e-34 3 185 111 289
Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell wall/membrane/envelope biogenesis].
pfam01464 SLT 9.31e-33 42 150 3 108
Transglycosylase SLT domain. This family is distantly related to pfam00062. Members are found in phages, type II, type III and type IV secretion systems.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
SNV63004.1 2.63e-58 1 183 1 180
ARF99123.1 5.28e-58 1 185 1 182
CAB1276067.1 7.49e-58 1 183 1 180
AXB81730.1 1.88e-57 28 184 34 190
ALG43012.1 5.35e-57 10 183 16 189

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
5MPQ_A 4.40e-23 36 183 416 559
BulgecinA: The key to a broad-spectrum inhibitor that targets lytic transglycosylases [Neisseria meningitidis]
5O1J_A 4.42e-23 36 183 420 563
Lytictransglycosylase in action [Neisseria meningitidis MC58]
6FPN_B 4.45e-23 36 183 426 569
Lytictransglycosylase in action [Neisseria meningitidis MC58]
5O24_A 4.47e-23 36 183 430 573
Lytictransglycosylase in action [Neisseria meningitidis]
5O29_A 4.50e-23 36 183 436 579
Lytictransglycosylase in action [Neisseria meningitidis]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
P0AGC3 1.62e-21 32 180 476 626
Soluble lytic murein transglycosylase OS=Escherichia coli (strain K12) OX=83333 GN=slt PE=1 SV=1
P0AGC4 1.62e-21 32 180 476 626
Soluble lytic murein transglycosylase OS=Escherichia coli O157:H7 OX=83334 GN=slt PE=3 SV=1
P39434 3.01e-21 32 185 476 631
Soluble lytic murein transglycosylase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) OX=99287 GN=slt PE=3 SV=2
O64046 3.52e-21 36 178 1422 1543
Probable tape measure protein OS=Bacillus phage SPbeta OX=66797 GN=yomI PE=3 SV=1
O31976 3.52e-21 36 178 1422 1543
SPbeta prophage-derived uncharacterized transglycosylase YomI OS=Bacillus subtilis (strain 168) OX=224308 GN=yomI PE=3 SV=2

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.610382 0.387401 0.001105 0.000284 0.000235 0.000599

TMHMM  Annotations      download full data without filtering help

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