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CAZyme Information: MGYG000003747_01970
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_C; Negativicutes; Veillonellales; Megasphaeraceae; Megasphaera; | |||||||||||
| CAZyme ID | MGYG000003747_01970 | |||||||||||
| CAZy Family | GT83 | |||||||||||
| CAZyme Description | Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 164; End: 1849 Strand: + | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT83 | 7 | 523 | 1.7e-116 | 0.9592592592592593 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| PRK13279 | arnT | 2.14e-64 | 12 | 373 | 11 | 365 | lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase. |
| COG1807 | ArnT | 5.65e-59 | 7 | 449 | 4 | 452 | 4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family [Cell wall/membrane/envelope biogenesis]. |
| pfam13231 | PMT_2 | 8.12e-16 | 67 | 226 | 2 | 160 | Dolichyl-phosphate-mannose-protein mannosyltransferase. This family contains members that are not captured by pfam02366. |
| pfam02366 | PMT | 4.99e-09 | 40 | 239 | 34 | 245 | Dolichyl-phosphate-mannose-protein mannosyltransferase. This is a family of Dolichyl-phosphate-mannose-protein mannosyltransferase proteins EC:2.4.1.109. These proteins are responsible for O-linked glycosylation of proteins, they catalyze the reaction:- Dolichyl phosphate D-mannose + protein <=> dolichyl phosphate + O-D-mannosyl-protein. Also in this family is Drosophila rotated abdomen protein which is a putative mannosyltransferase. This family appears to be distantly related to pfam02516 (A Bateman pers. obs.). This family also contains sequences from ArnTs (4-amino-4-deoxy-L-arabinose lipid A transferase). They catalyze the addition of 4-amino-4-deoxy-l-arabinose (l-Ara4N) to the lipid A moiety of the lipopolysaccharide. This is a critical modification enabling bacteria (e.g. Escherichia coli and Salmonella typhimurium) to resist killing by antimicrobial peptides such as polymyxins. Members such as undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase are predicted to have 12 trans-membrane regions. The N-terminal portion of these proteins is hypothesized to have a conserved glycosylation activity which is shared between distantly related oligosaccharyltransferases ArnT and PglB families. |
| COG4745 | COG4745 | 1.00e-05 | 7 | 367 | 11 | 397 | Predicted membrane-bound mannosyltransferase [General function prediction only]. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| AVO73572.1 | 0.0 | 1 | 557 | 1 | 557 |
| CCC73616.1 | 0.0 | 1 | 557 | 1 | 557 |
| ALG43014.1 | 0.0 | 1 | 557 | 1 | 557 |
| AVO26253.1 | 0.0 | 1 | 557 | 1 | 557 |
| AXB81287.1 | 0.0 | 1 | 555 | 1 | 555 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 5EZM_A | 4.86e-52 | 16 | 521 | 37 | 544 | CrystalStructure of ArnT from Cupriavidus metallidurans in the apo state [Cupriavidus metallidurans CH34],5F15_A Crystal Structure of ArnT from Cupriavidus metallidurans bound to Undecaprenyl phosphate [Cupriavidus metallidurans CH34] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| Q3KCB9 | 3.59e-47 | 12 | 370 | 10 | 363 | Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase 2 OS=Pseudomonas fluorescens (strain Pf0-1) OX=205922 GN=arnT2 PE=3 SV=1 |
| Q1CIH9 | 5.36e-47 | 23 | 505 | 19 | 504 | Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase OS=Yersinia pestis bv. Antiqua (strain Nepal516) OX=377628 GN=arnT PE=3 SV=1 |
| A7FHH6 | 5.36e-47 | 23 | 505 | 19 | 504 | Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase OS=Yersinia pseudotuberculosis serotype O:1b (strain IP 31758) OX=349747 GN=arnT PE=3 SV=1 |
| A9R091 | 5.36e-47 | 23 | 505 | 19 | 504 | Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase OS=Yersinia pestis bv. Antiqua (strain Angola) OX=349746 GN=arnT PE=3 SV=1 |
| B1JJ32 | 5.36e-47 | 23 | 505 | 19 | 504 | Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase OS=Yersinia pseudotuberculosis serotype O:3 (strain YPIII) OX=502800 GN=arnT PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000031 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |
TMHMM Annotations download full data without filtering help
| start | end |
|---|---|
| 12 | 34 |
| 87 | 109 |
| 116 | 138 |
| 175 | 197 |
| 204 | 226 |
| 256 | 278 |
| 299 | 316 |
| 320 | 339 |
| 352 | 374 |
| 384 | 403 |
| 410 | 432 |
| 456 | 473 |