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CAZyme Information: MGYG000004127_00741
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Actinobacteriota; Actinomycetia; Propionibacteriales; Propionibacteriaceae; ; | |||||||||||
| CAZyme ID | MGYG000004127_00741 | |||||||||||
| CAZy Family | GT39 | |||||||||||
| CAZyme Description | putative dolichyl-phosphate-mannose--protein mannosyltransferase | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 764; End: 2521 Strand: - | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT39 | 93 | 359 | 2.3e-73 | 0.9865470852017937 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| COG1928 | PMT1 | 2.83e-31 | 88 | 585 | 25 | 694 | Dolichyl-phosphate-mannose--protein O-mannosyl transferase [Posttranslational modification, protein turnover, chaperones]. |
| pfam02366 | PMT | 6.12e-20 | 91 | 335 | 1 | 223 | Dolichyl-phosphate-mannose-protein mannosyltransferase. This is a family of Dolichyl-phosphate-mannose-protein mannosyltransferase proteins EC:2.4.1.109. These proteins are responsible for O-linked glycosylation of proteins, they catalyze the reaction:- Dolichyl phosphate D-mannose + protein <=> dolichyl phosphate + O-D-mannosyl-protein. Also in this family is Drosophila rotated abdomen protein which is a putative mannosyltransferase. This family appears to be distantly related to pfam02516 (A Bateman pers. obs.). This family also contains sequences from ArnTs (4-amino-4-deoxy-L-arabinose lipid A transferase). They catalyze the addition of 4-amino-4-deoxy-l-arabinose (l-Ara4N) to the lipid A moiety of the lipopolysaccharide. This is a critical modification enabling bacteria (e.g. Escherichia coli and Salmonella typhimurium) to resist killing by antimicrobial peptides such as polymyxins. Members such as undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase are predicted to have 12 trans-membrane regions. The N-terminal portion of these proteins is hypothesized to have a conserved glycosylation activity which is shared between distantly related oligosaccharyltransferases ArnT and PglB families. |
| COG1807 | ArnT | 8.04e-13 | 91 | 335 | 11 | 213 | 4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family [Cell wall/membrane/envelope biogenesis]. |
| COG4346 | COG4346 | 8.93e-11 | 159 | 251 | 136 | 227 | Predicted membrane-bound dolichyl-phosphate-mannose-protein mannosyltransferase [Posttranslational modification, protein turnover, chaperones]. |
| pfam13231 | PMT_2 | 6.50e-10 | 158 | 335 | 1 | 149 | Dolichyl-phosphate-mannose-protein mannosyltransferase. This family contains members that are not captured by pfam02366. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| SDS30637.1 | 7.90e-231 | 70 | 585 | 21 | 539 |
| QIK71627.1 | 2.47e-229 | 71 | 585 | 5 | 518 |
| QDP97963.1 | 9.57e-229 | 72 | 585 | 40 | 556 |
| SDR91313.1 | 3.99e-227 | 70 | 585 | 30 | 543 |
| SDU97223.1 | 2.07e-224 | 72 | 585 | 31 | 542 |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P9WN04 | 3.56e-87 | 82 | 584 | 39 | 521 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) OX=83331 GN=pmt PE=3 SV=2 |
| P9WN05 | 3.56e-87 | 82 | 584 | 39 | 521 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=pmt PE=1 SV=2 |
| L8F4Z2 | 3.51e-85 | 82 | 584 | 33 | 515 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycolicibacterium smegmatis (strain MKD8) OX=1214915 GN=pmt PE=3 SV=1 |
| Q8NRZ6 | 1.07e-64 | 112 | 584 | 63 | 519 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) OX=196627 GN=pmt PE=3 SV=1 |
| Q8BGQ4 | 3.34e-06 | 85 | 317 | 125 | 334 | Protein O-mannosyl-transferase 2 OS=Mus musculus OX=10090 GN=Pomt2 PE=1 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.999260 | 0.000781 | 0.000007 | 0.000001 | 0.000001 | 0.000001 |
TMHMM Annotations download full data without filtering help
| start | end |
|---|---|
| 84 | 106 |
| 178 | 200 |
| 207 | 226 |
| 230 | 249 |
| 262 | 284 |
| 299 | 318 |
| 330 | 352 |
| 461 | 480 |
| 485 | 503 |
| 508 | 530 |
| 543 | 565 |