dbCAN-seq: a database of CAZyme sequence and annotation

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CAZyme Information: MGYG000004243_00637

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Basic Information help

Species

Lineage

Bacteria; Firmicutes_A; Clostridia; UMGS1810; UMGS1810; ;

CAZyme ID

MGYG000004243_00637

CAZy Family

GH18

CAZyme Description

hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
649		74420.4	4.7338

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000004243	1710627	MAG	United Kingdom	Europe

Gene Location

Start: 1556; End: 3505 Strand: -

Full Sequence Download help

Enzyme Prediction help

No EC number prediction in MGYG000004243_00637.

CAZyme Signature Domains help

Family	Start	End	Evalue	family coverage
GH18	381	634	1.5e-25	0.777027027027027

CDD Domains download full data without filtering help

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
cd02874	GH18_CFLE_spore_hydrolase	2.38e-52	346	644	23	313	Cortical fragment-lytic enzyme (CFLE) is a peptidoglycan hydrolase involved in bacterial endospore germination. CFLE is expressed as an inactive preprotein (called SleB) in the forespore compartment of sporulating cells. SleB translocates across the forespore inner membrane and is deposited as a mature enzyme in the cortex layer of the spore. As part of a sensory mechanism capable of initiating germination, CFLE degrades a spore-specific peptidoglycan constituent called muramic-acid delta-lactam that comprises the outer cortex. CFLE has a C-terminal glycosyl hydrolase family 18 (GH18) catalytic domain as well as two N-terminal LysM peptidoglycan-binding domains. In addition to SleB, this family includes YaaH, YdhD, and YvbX from Bacillus subtilis.
COG3858	YaaH	4.08e-32	368	649	135	423	Spore germination protein YaaH [Cell cycle control, cell division, chromosome partitioning].
pfam00704	Glyco_hydro_18	1.59e-20	334	631	8	302	Glycosyl hydrolases family 18.
smart00636	Glyco_18	3.59e-16	383	631	50	329	Glyco_18 domain.
NF033190	inl_like_NEAT_1	3.87e-11	45	204	589	749	NEAT domain-containing leucine-rich repeat protein. Members of this family have an N-terminal NEAT (near transporter) domain often associated with iron transport, followed by a leucine-rich repeat region with significant sequence similarity to the internalins of Listeria monocytogenes. However, since Bacillus cereus (from which this protein was described, in PMID:16978259) is not considered an intracellular pathogen, and the function may be iron transport rather than internalization, applying the name "internalin" to this family probably would be misleading.

CAZyme Hits help

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
AUG58279.1	1.63e-128	9	649	1	696
QXM06578.1	5.93e-62	328	649	234	552
QSQ09420.1	6.01e-61	330	644	234	542
QZY55662.1	2.98e-59	328	649	234	552
QRG68543.1	2.82e-57	327	649	260	579

PDB Hits download full data without filtering help

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
3CZ8_A	7.68e-18	408	632	81	307	ChainA, Putative sporulation-specific glycosylase ydhD [Bacillus subtilis subsp. subtilis str. 168],3CZ8_B Chain B, Putative sporulation-specific glycosylase ydhD [Bacillus subtilis subsp. subtilis str. 168]
5JH8_A	3.31e-11	422	646	88	312	Crystalstructure of chitinase from Chromobacterium violaceum ATCC 12472 [Chromobacterium violaceum ATCC 12472]
4WIW_A	2.37e-10	342	634	27	330	ChainA, Glycoside hydrolase family 18 [Desulfitobacterium hafniense DCB-2],4WIW_B Chain B, Glycoside hydrolase family 18 [Desulfitobacterium hafniense DCB-2],4WIW_C Chain C, Glycoside hydrolase family 18 [Desulfitobacterium hafniense DCB-2],4WIW_D Chain D, Glycoside hydrolase family 18 [Desulfitobacterium hafniense DCB-2],4WIW_E Chain E, Glycoside hydrolase family 18 [Desulfitobacterium hafniense DCB-2],4WIW_F Chain F, Glycoside hydrolase family 18 [Desulfitobacterium hafniense DCB-2]
6JM7_A	1.85e-06	427	638	106	352	Crystalstructure of Ostrinia furnacalis Group IV chitinase [Ostrinia furnacalis],6JMB_A Chain A, ofchtiv-allosamidin [Ostrinia furnacalis]
4AQ1_A	6.56e-06	48	204	12	165	Structureof the SbsB S-layer protein of Geobacillus stearothermophilus PV72p2 in complex with nanobody KB6 [Geobacillus stearothermophilus]

Swiss-Prot Hits download full data without filtering help

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
O32258	2.60e-20	390	646	77	341	Uncharacterized glycosylase YvbX OS=Bacillus subtilis (strain 168) OX=224308 GN=yvbX PE=3 SV=1
P38536	3.11e-17	28	211	1671	1859	Amylopullulanase OS=Thermoanaerobacterium thermosulfurigenes OX=33950 GN=amyB PE=3 SV=2
O05495	8.87e-17	408	632	173	399	Putative sporulation-specific glycosylase YdhD OS=Bacillus subtilis (strain 168) OX=224308 GN=ydhD PE=1 SV=2
P19424	2.87e-16	8	230	5	228	Endoglucanase OS=Bacillus sp. (strain KSM-635) OX=1415 PE=1 SV=1
O31682	3.54e-14	440	556	99	214	Putative glycosylase YkvQ OS=Bacillus subtilis (strain 168) OX=224308 GN=ykvQ PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.005284	0.991657	0.002332	0.000231	0.000222	0.000243

TMHMM Annotations download full data without filtering help

start	end
12	31