You are browsing environment: HUMAN GUT
CAZyme Information: MGYG000004871_00692
You are here: Home > Sequence: MGYG000004871_00692
Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Muribaculaceae; CAG-485; | |||||||||||
| CAZyme ID | MGYG000004871_00692 | |||||||||||
| CAZy Family | GT2 | |||||||||||
| CAZyme Description | Tyrocidine synthase 3 | |||||||||||
| CAZyme Property |
|
|||||||||||
| Genome Property |
|
|||||||||||
| Gene Location | Start: 61192; End: 68442 Strand: - | |||||||||||
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| PRK12467 | PRK12467 | 0.0 | 24 | 2002 | 71 | 2161 | peptide synthase; Provisional |
| PRK12316 | PRK12316 | 0.0 | 38 | 2001 | 1591 | 3619 | peptide synthase; Provisional |
| PRK05691 | PRK05691 | 0.0 | 24 | 2016 | 697 | 2784 | peptide synthase; Validated |
| cd05930 | A_NRPS | 4.47e-153 | 442 | 903 | 1 | 444 | The adenylation domain of nonribosomal peptide synthetases (NRPS). The adenylation (A) domain of NRPS recognizes a specific amino acid or hydroxy acid and activates it as an (amino) acyl adenylate by hydrolysis of ATP. The activated acyl moiety then forms a thioester bond to the enzyme-bound cofactor phosphopantetheine of a peptidyl carrier protein domain. NRPSs are large multifunctional enzymes which synthesize many therapeutically useful peptides in bacteria and fungi via a template-directed, nucleic acid independent nonribosomal mechanism. These natural products include antibiotics, immunosuppressants, plant and animal toxins, and enzyme inhibitors. NRPS has a distinct modular structure in which each module is responsible for the recognition, activation, and in some cases, modification of a single amino acid residue of the final peptide product. The modules can be subdivided into domains that catalyze specific biochemical reactions. |
| PRK12316 | PRK12316 | 5.11e-150 | 1019 | 2010 | 63 | 1092 | peptide synthase; Provisional |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QND46664.1 | 1.68e-196 | 4 | 1991 | 564 | 2649 |
| ACX49739.1 | 1.58e-128 | 5 | 1715 | 11 | 1846 |
| BAY30132.1 | 1.57e-86 | 25 | 963 | 2269 | 3270 |
| BAY90071.1 | 1.33e-83 | 25 | 963 | 2258 | 3259 |
| BAZ00088.1 | 3.01e-83 | 25 | 963 | 2267 | 3268 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 6MFZ_A | 1.75e-209 | 442 | 1992 | 219 | 1785 | Crystalstructure of dimodular LgrA in a condensation state [Brevibacillus parabrevis],6MFZ_B Crystal structure of dimodular LgrA in a condensation state [Brevibacillus parabrevis] |
| 6MFY_A | 1.21e-198 | 442 | 1924 | 219 | 1715 | Crystalstructure of a 5-domain construct of LgrA in the substrate donation state [Brevibacillus parabrevis],6MG0_A Crystal structure of a 5-domain construct of LgrA in the thiolation state [Brevibacillus parabrevis],6MG0_B Crystal structure of a 5-domain construct of LgrA in the thiolation state [Brevibacillus parabrevis] |
| 6MFX_A | 1.80e-112 | 442 | 1399 | 219 | 1178 | Crystalstructure of a 4-domain construct of a mutant of LgrA in the substrate donation state [Brevibacillus parabrevis] |
| 6MFW_A | 3.24e-112 | 442 | 1399 | 219 | 1178 | Crystalstructure of a 4-domain construct of LgrA in the substrate donation state [Brevibacillus parabrevis] |
| 5U89_A | 6.90e-102 | 438 | 1151 | 34 | 770 | Crystalstructure of a cross-module fragment from the dimodular NRPS DhbF [Geobacillus sp. Y4.1MC1] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| O68006 | 3.43e-237 | 5 | 1993 | 1673 | 3718 | Bacitracin synthase 1 OS=Bacillus licheniformis OX=1402 GN=bacA PE=3 SV=1 |
| O30409 | 1.74e-230 | 5 | 2001 | 1057 | 3108 | Tyrocidine synthase 3 OS=Brevibacillus parabrevis OX=54914 GN=tycC PE=1 SV=1 |
| O68007 | 1.80e-229 | 5 | 2010 | 77 | 2135 | Bacitracin synthase 2 OS=Bacillus licheniformis OX=1402 GN=bacB PE=3 SV=1 |
| P0C064 | 2.02e-227 | 5 | 2001 | 1063 | 3119 | Gramicidin S synthase 2 OS=Brevibacillus brevis OX=1393 GN=grsB PE=1 SV=2 |
| O30408 | 3.51e-227 | 25 | 1992 | 1085 | 3098 | Tyrocidine synthase 2 OS=Brevibacillus parabrevis OX=54914 GN=tycB PE=1 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000052 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |