cluster number:6588
GT4:33	GT4:33
LRPQGLDL:0.9393939393939394	PTLRPQGL:0.9393939393939394	RPQGLDLT:0.9393939393939394	TLRPQGLD:0.9393939393939394	PGGMERHA:0.8484848484848485	FVNPTLRP:0.8181818181818182	NPTLRPQG:0.8181818181818182	VNPTLRPQ:0.8181818181818182	PQGLDLTL:0.7272727272727273	AYERLFLC:0.6969696969696970	DLTLMEAM:0.6969696969696970	GLDLTLME:0.6969696969696970	LDLTLMEA:0.6969696969696970	QGLDLTLM:0.6969696969696970	ALAYERLF:0.6363636363636364	KMALAYER:0.6363636363636364	LAYERLFL:0.6363636363636364	MALAYERL:0.6363636363636364	AVFSRKWP:0.5757575757575758	EMLRDVYQ:0.5757575757575758	GEMLRDVY:0.5757575757575758	LRDVYQIP:0.5757575757575758	MLRDVYQI:0.5757575757575758	YERLFLCI:0.5757575757575758	GRLVKDKG:0.5151515151515151	LVKDKGHP:0.5151515151515151	RLVKDKGH:0.5151515151515151	DKGHPLLY:0.4848484848484849	ESVALPHW:0.4848484848484849	GHPLLYEA:0.4848484848484849	KGHPLLYE:0.4848484848484849	ERLFLCIK:0.4545454545454545	KDKGHPLL:0.4545454545454545	NLAVSWHG:0.4545454545454545	VHVILNGV:0.4545454545454545	VKDKGHPL:0.4545454545454545	AISDSCGE:0.4242424242424243	DSCGEMLR:0.4242424242424243	HSESVALP:0.4242424242424243	HVILNGVD:0.4242424242424243	ISDSCGEM:0.4242424242424243	RVHVILNG:0.4242424242424243	SCGEMLRD:0.4242424242424243	SDSCGEML:0.4242424242424243	SESVALPH:0.4242424242424243	VHSESVAL:0.4242424242424243	WHGIALES:0.4242424242424243	WRYNKAWE:0.4242424242424243	AGRLVKDK:0.3939393939393939	ALESLQSS:0.3939393939393939	AVSWHGIA:0.3939393939393939	CGEMLRDV:0.3939393939393939	GIALESLQ:0.3939393939393939	HGIALESL:0.3939393939393939	IALESLQS:0.3939393939393939	LAVSWHGI:0.3939393939393939	PNVESLLE:0.3939393939393939	SWHGIALE:0.3939393939393939	VILNGVDE:0.3939393939393939	VSWHGIAL:0.3939393939393939	ALPHWIAR:0.3636363636363636	HPLLYEAF:0.3636363636363636	IAVFSRKW:0.3636363636363636	IVVDDEFG:0.3636363636363636	KIAVFSRK:0.3636363636363636	LESLQSSI:0.3636363636363636	LKIAVFSR:0.3636363636363636	SVALPHWI:0.3636363636363636	VALPHWIA:0.3636363636363636	FSPNVESL:0.3333333333333333	FYNALDVF:0.3333333333333333	GKACREYA:0.3333333333333333	GRLVRDKG:0.3333333333333333	HVIVNGVD:0.3333333333333333	LRAFYNAI:0.3333333333333333	LTLMEAMM:0.3333333333333333	MFSPNVES:0.3333333333333333	MFTARKMA:0.3333333333333333	RAFYNAID:0.3333333333333333	RGKACREY:0.3333333333333333	RLVRDKGH:0.3333333333333333	TALARRGH:0.3333333333333333	TLMEAMMS:0.3333333333333333	VHVIVNGV:0.3333333333333333	YNALDVFV:0.3333333333333333	AFYNAIDI:0.3030303030303030	AHHVAISD:0.3030303030303030	AIDIFVNP:0.3030303030303030	AMQCGKPV:0.3030303030303030	DIFVNPTL:0.3030303030303030	DVFVNPTL:0.3030303030303030	EAMQCGKP:0.3030303030303030	FYNAIDIF:0.3030303030303030	GHRVHVFT:0.3030303030303030	HRVHVFTS:0.3030303030303030	IDIFVNPT:0.3030303030303030	IFVNPTLR:0.3030303030303030	KPLLASRF:0.3030303030303030	MLRAFYNA:0.3030303030303030	NAIDIFVN:0.3030303030303030	PLLASRFP:0.3030303030303030	PNLAVSWH:0.3030303030303030	RGHRVHVF:0.3030303030303030	RVHVFTSP:0.3030303030303030	SMFTARKM:0.3030303030303030	SMLRAFYN:0.3030303030303030	VAGSGPWE:0.3030303030303030	VFVNPTLR:0.3030303030303030	YAHHVAIS:0.3030303030303030	YNAIDIFV:0.3030303030303030	AHTLHTAL:0.2727272727272727	ARKMALAY:0.2727272727272727	ARRGKACR:0.2727272727272727	DDEFGFMF:0.2727272727272727	DEFGFMFS:0.2727272727272727	DVVHSESV:0.2727272727272727	DVYQIPSR:0.2727272727272727	EFGFMFSP:0.2727272727272727	ERHAHTLH:0.2727272727272727	FAPNVEAL:0.2727272727272727	FDVVHSES:0.2727272727272727	FGFMFSPN:0.2727272727272727	FMFSPNVE:0.2727272727272727	FTARKMAL:0.2727272727272727	GFMFSPNV:0.2727272727272727	GGMERHAH:0.2727272727272727	GMERHAHT:0.2727272727272727	GTIVVDDE:0.2727272727272727	HAHTLHTA:0.2727272727272727	HTLHTALA:0.2727272727272727	IKGTIVVD:0.2727272727272727	IPSRRVHV:0.2727272727272727	KGTIVVDD:0.2727272727272727	LARRGKAC:0.2727272727272727	LVRDKGHP:0.2727272727272727	MERHAHTL:0.2727272727272727	NVESLLEA:0.2727272727272727	PSMLRAFY:0.2727272727272727	PSRRVHVI:0.2727272727272727	QIPSRRVH:0.2727272727272727	RDKGHPLL:0.2727272727272727	RDVYQIPS:0.2727272727272727	RHAHTLHT:0.2727272727272727	RKMALAYE:0.2727272727272727	RRGKACRE:0.2727272727272727	SPNVESLL:0.2727272727272727	TARKMALA:0.2727272727272727	VDDEFGFM:0.2727272727272727	VRDKGHPL:0.2727272727272727	VVDDEFGF:0.2727272727272727	VVHSESVA:0.2727272727272727	VYQIPSRR:0.2727272727272727	YQIPSRRV:0.2727272727272727	ACREYANS:0.2424242424242424	AHHIAISD:0.2424242424242424	ANSMFTAR:0.2424242424242424	ASAYERFF:0.2424242424242424	AVTWHGIW:0.2424242424242424	CREYANSM:0.2424242424242424	DPSMLRAF:0.2424242424242424	DYVHTESV:0.2424242424242424	EPFDVVHS:0.2424242424242424	EPGKWRYN:0.2424242424242424	EYANSMFT:0.2424242424242424	FDYVHTES:0.2424242424242424	GGMERHAF:0.2424242424242424	GGMERHAY:0.2424242424242424	GIWYEIMH:0.2424242424242424	GKWRYNKA:0.2424242424242424	GMERHAFT:0.2424242424242424	GMERHAYT:0.2424242424242424	GYTFSPNV:0.2424242424242424	HGIWYEIM:0.2424242424242424	HHIAISDS:0.2424242424242424	HIAISDSC:0.2424242424242424	HICISNSA:0.2424242424242424	IAISDSCG:0.2424242424242424	IWYEIMHS:0.2424242424242424	KACREYAN:0.2424242424242424	KRVHVILN:0.2424242424242424	KWRYNKAW:0.2424242424242424	LFLCIKKD:0.2424242424242424	LVVAGSGP:0.2424242424242424	MASAYERF:0.2424242424242424	MDPSMLRA:0.2424242424242424	MERHAFTL:0.2424242424242424	MERHAYTL:0.2424242424242424	NSMFTARK:0.2424242424242424	NYPSIVGT:0.2424242424242424	PFDVVHSE:0.2424242424242424	PGKWRYNK:0.2424242424242424	PNYPSIVG:0.2424242424242424	QHICISNS:0.2424242424242424	REYANSMF:0.2424242424242424	RLFLCIKK:0.2424242424242424	TIVVDDEF:0.2424242424242424	TWHGIWYE:0.2424242424242424	VAGSGPWG:0.2424242424242424	VFSRKWPT:0.2424242424242424	VTWHGIWY:0.2424242424242424	VVAGSGPW:0.2424242424242424	WHGIWYEI:0.2424242424242424	YAHHIAIS:0.2424242424242424	YANSMFTA:0.2424242424242424	YPSIVGTV:0.2424242424242424	AAGRLVKD:0.2121212121212121	AEGAERLA:0.2121212121212121	AEPGKWRY:0.2121212121212121	AERGRKCK:0.2121212121212121	AERLAERG:0.2121212121212121	AFKNHSSR:0.2121212121212121	AFTLYTAL:0.2121212121212121	AGDLRDLT:0.2121212121212121	AGSGPWGK:0.2121212121212121	ALDVFVNP:0.2121212121212121	ALFLLRTS:0.2121212121212121	ALTAVMEV:0.2121212121212121	AMLSGKPV:0.2121212121212121	APNVEALT:0.2121212121212121	AQFAWNRL:0.2121212121212121	AREVLVNI:0.2121212121212121	ARFRAKHG:0.2121212121212121	ASLYGAVL:0.2121212121212121	ASQTKLKK:0.2121212121212121	ASRFPSIK:0.2121212121212121	ASRYASIK:0.2121212121212121	ATQMASAY:0.2121212121212121	AVAEGAER:0.2121212121212121	AVFCKSWP:0.2121212121212121	AVLPKILD:0.2121212121212121	AVMEVAVA:0.2121212121212121	AWELYQEE:0.2121212121212121	AYERFFMC:0.2121212121212121	AYTLYTSL:0.2121212121212121	CISNSARE:0.2121212121212121	CKEYAAEM:0.2121212121212121	CKSWPVGS:0.2121212121212121	CTFLFFTV:0.2121212121212121	DAEPGKWR:0.2121212121212121	DEIRFFHN:0.2121212121212121	DERFGYTF:0.2121212121212121	DLFVNPTL:0.2121212121212121	DLQTAQFA:0.2121212121212121	DLTIIEAM:0.2121212121212121	DQTKFVYS:0.2121212121212121	DVYQIPEK:0.2121212121212121	EALTAVME:0.2121212121212121	EAMLSGKP:0.2121212121212121	EENKKEPF:0.2121212121212121	EGAERLAE:0.2121212121212121	EIRFFHNY:0.2121212121212121	EKLKLAVF:0.2121212121212121	EKRVHVIL:0.2121212121212121	ELKGFYNG:0.2121212121212121	ELYQEENK:0.2121212121212121	ENPPFAGD:0.2121212121212121	EPRSQGFN:0.2121212121212121	ERFGYTFS:0.2121212121212121	ERGRKCKE:0.2121212121212121	ERHAFTLY:0.2121212121212121	ERHAYTLY:0.2121212121212121	ERLAERGR:0.2121212121212121	ERYCRYPL:0.2121212121212121	ESLQSSIY:0.2121212121212121	ETLDSVVR:0.2121212121212121	EVAVAEGA:0.2121212121212121	EVLVNIYQ:0.2121212121212121	EYAAEMFT:0.2121212121212121	FAGDLRDL:0.2121212121212121	FCKSWPVG:0.2121212121212121	FFHNYAHH:0.2121212121212121	FFTVLFTI:0.2121212121212121	FGFMFAPN:0.2121212121212121	FGYTFSPN:0.2121212121212121	FHNYAHHI:0.2121212121212121	FKNHSSRT:0.2121212121212121	FLFFTVLF:0.2121212121212121	FMFAPNVE:0.2121212121212121	FNASLYGA:0.2121212121212121	FSLCTFLF:0.2121212121212121	FSPNVRSL:0.2121212121212121	FSRKWPTG:0.2121212121212121	FTATQMAS:0.2121212121212121	FTIPALFL:0.2121212121212121	FTLYTALA:0.2121212121212121	FTVLFTIP:0.2121212121212121	FTVSSDRS:0.2121212121212121	FYNGIDLF:0.2121212121212121	GAAGRLVK:0.2121212121212121	GAERLAER:0.2121212121212121	GARFRAKH:0.2121212121212121	GAVLPKIL:0.2121212121212121	GDAEPGKW:0.2121212121212121	GDLQTAQF:0.2121212121212121	GFMFAPNV:0.2121212121212121	GFNASLYG:0.2121212121212121	GFYNALDV:0.2121212121212121	GFYNGIDL:0.2121212121212121	GIDLFVNP:0.2121212121212121	GKPVMASR:0.2121212121212121	GKRYAELG:0.2121212121212121	GLDLTIIE:0.2121212121212121	GPISEKLK:0.2121212121212121	GPNPGGME:0.2121212121212121	GPWGKRYA:0.2121212121212121	GRKCKEYA:0.2121212121212121	GSGPWGKR:0.2121212121212121	GSIPGGME:0.2121212121212121	GSLNPNEL:0.2121212121212121	GTVVVDER:0.2121212121212121	GVDQTKFV:0.2121212121212121	GVSGRLVR:0.2121212121212121	HAFTLYTA:0.2121212121212121	HAYTLYTS:0.2121212121212121	HFSLCTFL:0.2121212121212121	HGDAEPGK:0.2121212121212121	HNYAHHIA:0.2121212121212121	HSHGDAEP:0.2121212121212121	HVFTSPLD:0.2121212121212121	HVFTVSSD:0.2121212121212121	ICISNSAR:0.2121212121212121	IDLFVNPT:0.2121212121212121	IEAMQCGK:0.2121212121212121	IHSHGDAE:0.2121212121212121	ILDEIRFF:0.2121212121212121	ILGSLNPN:0.2121212121212121	ILNGVDEN:0.2121212121212121	IPALFLLR:0.2121212121212121	IPEKRVHV:0.2121212121212121	IPGGMERH:0.2121212121212121	IRFFHNYA:0.2121212121212121	ISEKLKLA:0.2121212121212121	ISNSAREV:0.2121212121212121	IVAGSGPW:0.2121212121212121	IVGTVVVD:0.2121212121212121	IVLGAAGR:0.2121212121212121	IVMGVSGR:0.2121212121212121	IVNGVDQT:0.2121212121212121	IYQDLIRK:0.2121212121212121	KAWELYQE:0.2121212121212121	KCKEYAAE:0.2121212121212121	KEYAAEMF:0.2121212121212121	KGFYNGID:0.2121212121212121	KILDEIRF:0.2121212121212121	KKPNSHFS:0.2121212121212121	KLAVFCKS:0.2121212121212121	KLKKPNSH:0.2121212121212121	KLKLAVFC:0.2121212121212121	KPNSHFSL:0.2121212121212121	KPVMASRY:0.2121212121212121	KQHICISN:0.2121212121212121	KSWPVGSI:0.2121212121212121	KWPTGPNP:0.2121212121212121	LAERGRKC:0.2121212121212121	LAVFCKSW:0.2121212121212121	LAVFSRKW:0.2121212121212121	LCTFLFFT:0.2121212121212121	LDEIRFFH:0.2121212121212121	LDLTIIEA:0.2121212121212121	LDSVVRDG:0.2121212121212121	LDVFVNPT:0.2121212121212121	LFFTVLFT:0.2121212121212121	LFRSKLGL:0.2121212121212121	LFTIPALF:0.2121212121212121	LFVNPTLR:0.2121212121212121	LGAAGRLV:0.2121212121212121	LGSLNPNE:0.2121212121212121	LGVAGRLV:0.2121212121212121	LIVAGSGP:0.2121212121212121	LKGFYNGI:0.2121212121212121	LKKPNSHF:0.2121212121212121	LKLAVFCK:0.2121212121212121	LLVAGSGP:0.2121212121212121	LLYEAFAL:0.2121212121212121	LMEAMLSG:0.2121212121212121	LMEAMMSG:0.2121212121212121	LNGVDENG:0.2121212121212121	LNPNELKG:0.2121212121212121	LPHWRVKM:0.2121212121212121	LPKILDEI:0.2121212121212121	LQSSIYQD:0.2121212121212121	LQTAQFAW:0.2121212121212121	LSGKPVMA:0.2121212121212121	LTAVMEVA:0.2121212121212121	LTIIEAMQ:0.2121212121212121	LTLMEAML:0.2121212121212121	LVAGSGPW:0.2121212121212121	LVDEIRFF:0.2121212121212121	LVETLDSV:0.2121212121212121	LVLGVAGR:0.2121212121212121	LVNIYQLP:0.2121212121212121	LYGAVLPK:0.2121212121212121	LYQEENKK:0.2121212121212121	LYTALARR:0.2121212121212121	LYTSLASR:0.2121212121212121	MAFKNHSS:0.2121212121212121	MASQTKLK:0.2121212121212121	MASRYASI:0.2121212121212121	MEAMLSGK:0.2121212121212121	MEAMMSGK:0.2121212121212121	MEVAVAEG:0.2121212121212121	MFAPNVEA:0.2121212121212121	MFTATQMA:0.2121212121212121	MGVSGRLV:0.2121212121212121	MLSGKPVM:0.2121212121212121	MPRLVDEI:0.2121212121212121	NALDVFVN:0.2121212121212121	NASLYGAV:0.2121212121212121	NELKGFYN:0.2121212121212121	NERYCRYP:0.2121212121212121	NGIDLFVN:0.2121212121212121	NGVDENGF:0.2121212121212121	NGVDQTKF:0.2121212121212121	NIYQLPKR:0.2121212121212121	NKAWELYQ:0.2121212121212121	NPGGMERH:0.2121212121212121	NPNELKGF:0.2121212121212121	NPPFAGDL:0.2121212121212121	NSAREVLV:0.2121212121212121	NSHFSLCT:0.2121212121212121	NVEALTAV:0.2121212121212121	NVRSLVET:0.2121212121212121	NYAHHIAI:0.2121212121212121	PALFLLRT:0.2121212121212121	PEKRVHVI:0.2121212121212121	PFAGDLRD:0.2121212121212121	PHWRVKMV:0.2121212121212121	PISEKLKL:0.2121212121212121	PKILDEIR:0.2121212121212121	PLLYEAFA:0.2121212121212121	PNELKGFY:0.2121212121212121	PNPGGMER:0.2121212121212121	PNSHFSLC:0.2121212121212121	PNVEALTA:0.2121212121212121	PNVRSLVE:0.2121212121212121	PPFAGDLR:0.2121212121212121	PPWSGDLQ:0.2121212121212121	PQGLDLTI:0.2121212121212121	PRLVDEIR:0.2121212121212121	PRSQGFNA:0.2121212121212121	PSIVGTVV:0.2121212121212121	PTGPNPGG:0.2121212121212121	PVGSIPGG:0.2121212121212121	PVMASRYA:0.2121212121212121	PWGKRYAE:0.2121212121212121	PWSGDLQT:0.2121212121212121	QEENKKEP:0.2121212121212121	QGFNASLY:0.2121212121212121	QGLDLTII:0.2121212121212121	QIPEKRVH:0.2121212121212121	QMASAYER:0.2121212121212121	QPPWSGDL:0.2121212121212121	QSSIYQDL:0.2121212121212121	QTAQFAWN:0.2121212121212121	QTKFVYSP:0.2121212121212121	QTKLKKPN:0.2121212121212121	RDVYQIPE:0.2121212121212121	REPFDVVH:0.2121212121212121	REVLVNIY:0.2121212121212121	RFFHNYAH:0.2121212121212121	RFGYTFSP:0.2121212121212121	RFPSIKGT:0.2121212121212121	RGRKCKEY:0.2121212121212121	RHAFTLYT:0.2121212121212121	RHAYTLYT:0.2121212121212121	RKCKEYAA:0.2121212121212121	RKWPTGPN:0.2121212121212121	RLAERGRK:0.2121212121212121	RLVDEIRF:0.2121212121212121	RSLVETLD:0.2121212121212121	RSQGFNAS:0.2121212121212121	RYKELGEK:0.2121212121212121	RYNKAWEL:0.2121212121212121	RYNKAWEQ:0.2121212121212121	SAREVLVN:0.2121212121212121	SAYERFFM:0.2121212121212121	SEKLKLAV:0.2121212121212121	SGDLQTAQ:0.2121212121212121	SGKPVMAS:0.2121212121212121	SGPWGKRY:0.2121212121212121	SGRLVRDK:0.2121212121212121	SHFSLCTF:0.2121212121212121	SHGDAEPG:0.2121212121212121	SIPGGMER:0.2121212121212121	SIVGTVVV:0.2121212121212121	SIYQDLIR:0.2121212121212121	SLASRGHE:0.2121212121212121	SLCTFLFF:0.2121212121212121	SLNPNELK:0.2121212121212121	SLQSSIYQ:0.2121212121212121	SLVETLDS:0.2121212121212121	SLYGAVLP:0.2121212121212121	SMFTATQM:0.2121212121212121	SNSAREVL:0.2121212121212121	SPNVRSLV:0.2121212121212121	SQGFNASL:0.2121212121212121	SQTKLKKP:0.2121212121212121	SRFPSIKG:0.2121212121212121	SRKWPTGP:0.2121212121212121	SRYASIKR:0.2121212121212121	SSIYQDLI:0.2121212121212121	SWPVGSIP:0.2121212121212121	TAQFAWNR:0.2121212121212121	TATQMASA:0.2121212121212121	TAVMEVAV:0.2121212121212121	TFLFFTVL:0.2121212121212121	TFSPNVRS:0.2121212121212121	TGPNPGGM:0.2121212121212121	TIIEAMQC:0.2121212121212121	TIPALFLL:0.2121212121212121	TKFVYSPE:0.2121212121212121	TKLKKPNS:0.2121212121212121	TLDSVVRD:0.2121212121212121	TLMEAMLS:0.2121212121212121	TLYTALAR:0.2121212121212121	TLYTSLAS:0.2121212121212121	TMPRLVDE:0.2121212121212121	TPGGMERH:0.2121212121212121	TQMASAYE:0.2121212121212121	TSLASRGH:0.2121212121212121	TTPGGMER:0.2121212121212121	TVLFTIPA:0.2121212121212121	TVSSDRSN:0.2121212121212121	TVVVDERF:0.2121212121212121	VAEGAERL:0.2121212121212121	VAVAEGAE:0.2121212121212121	VDEIRFFP:0.2121212121212121	VDERFGYT:0.2121212121212121	VDQTKFVY:0.2121212121212121	VEALTAVM:0.2121212121212121	VETLDSVV:0.2121212121212121	VFCKSWPV:0.2121212121212121	VFTVSSDR:0.2121212121212121	VGSIPGGM:0.2121212121212121	VGTVVVDE:0.2121212121212121	VHVFTSPL:0.2121212121212121	VHVFTSPP:0.2121212121212121	VIVNGVDQ:0.2121212121212121	VLFTIPAL:0.2121212121212121	VLGAAGRL:0.2121212121212121	VLGVAGRL:0.2121212121212121	VLPKILDE:0.2121212121212121	VLVNIYQL:0.2121212121212121	VMASRYAS:0.2121212121212121	VMEVAVAE:0.2121212121212121	VMGVSGRL:0.2121212121212121	VNGVDQTK:0.2121212121212121	VNIYQLPK:0.2121212121212121	VPNLAVSW:0.2121212121212121	VRSLVETL:0.2121212121212121	VSGRLVRD:0.2121212121212121	VSSDRSNR:0.2121212121212121	VVDERFGY:0.2121212121212121	VVVDERFG:0.2121212121212121	VYLIVAGS:0.2121212121212121	VYLLVAGS:0.2121212121212121	VYQIPEKR:0.2121212121212121	WELYQEEN:0.2121212121212121	WGKRYAEL:0.2121212121212121	WPTGPNPG:0.2121212121212121	WPVGSIPG:0.2121212121212121	WSGDLQTA:0.2121212121212121	YAAEMFTA:0.2121212121212121	YALSMFTA:0.2121212121212121	YERFFMCM:0.2121212121212121	YGAVLPKI:0.2121212121212121	YKELGEKV:0.2121212121212121	YKQHICIS:0.2121212121212121	YLIVAGSG:0.2121212121212121	YLLVAGSG:0.2121212121212121	YNGIDLFV:0.2121212121212121	YNKAWELY:0.2121212121212121	YNKAWEQF:0.2121212121212121	YQDLIRKP:0.2121212121212121	YQEENKKE:0.2121212121212121	YQIPEKRV:0.2121212121212121	YTALARRG:0.2121212121212121	YTFSPNVR:0.2121212121212121	YTLYTSLA:0.2121212121212121	YTSLASRG:0.2121212121212121