LOCUS       AB811614               19104 bp    DNA     linear   BCT 13-MAY-2015
DEFINITION  Escherichia coli DNA, O-antigen biosynthetic locus, strain: H510c.
ACCESSION   AB811614
VERSION     AB811614.1
KEYWORDS    .
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1
  AUTHORS   Iguchi,A., Iyoda,S., Kikuchi,T., Ogura,Y., Katsura,K., Ohnishi,M.,
            Hayashi,T. and Thomson,N.R.
  TITLE     A complete view of the genetic diversity of the Escherichia coli
            O-antigen biosynthesis gene cluster
  JOURNAL   DNA Res. 22 (1), 101-107 (2015)
   PUBMED   25428893
  REMARK    DOI:10.1093/dnares/dsu043
REFERENCE   2  (bases 1 to 19104)
  AUTHORS   Iguchi,A., Iyoda,S. and Ohnishi,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-MAR-2013) Contact:Atsushi Iguchi University of
            Miyazaki, Faculty of Agriculture; Gakuen-kibanadai-nishi 1-1,
            Miyazaki, Miyazaki 889-2192, Japan
FEATURES             Location/Qualifiers
     source          1..19104
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="H510c"
                     /db_xref="taxon:562"
                     /note="serogroup:O37"
     gene            <1..901
                     /gene="wcaM"
     CDS             <1..901
                     /gene="wcaM"
                     /codon_start=2
                     /transl_table=11
                     /protein_id="BAQ00839.1"
                     /translation="AILRQGFHNQIIGANITNCKFSDLQGDAIEWNVAIHDSDILISDH
                     LIERINCTNGKINWGIGIGLAGSTYDNNYPEDQAVKNFVVANITGSDCRQLIHVENGKH
                     FVIRNIKARNITPDFSKKAGIDNATVAIYGCDNFVIDNIEMINSAGMLIGYGVIKGKYL
                     SIPQNFRVNNIQLDNTHLAYKLRGIQISAGNAVSFVALTNIEMKRASLELHNKPQHLFM
                     RNIKVMQESSVGPALSMNFDMRKDVRGVFMAKKETLLSLANVHAVNERGQSSVDIDRIN
                     HHIVNVEKINFRLPERRE"
     gene            1059..2054
                     /gene="gne"
     CDS             1059..2054
                     /gene="gne"
                     /note="O037_01"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 4-epimerase"
                     /protein_id="BAQ00840.1"
                     /translation="MNDNVLLIGASGFVGTRLLETAIADFNIKNLDKQQSHFYPEITQI
                     GDVRDQQALDQALAGFDTVVLLAAEHRDDVSPTSLYYDVNVQGTRNVLAAMEKNGVKNI
                     IFTSSVAVYGLNKHNPDENHPHDPFNHYGKSKWQAEEVLREWYNKAPTERSLTIIRPTV
                     IFGERNRGNVYNLLKQIAGGKFMMVGAGTNYKSMAYVGNIVEFIKYKLKNVAAGYEVYN
                     YVDKPDLNMNQLVAEVEQSLNKKIPSMHLPYPLGMLGGYCFDILSKITGKKYAVSSVRV
                     KKFCATTQFDATKVHSSGFVAPYTLSQGLDRTLQYEFVHAKKDDITFVSE"
     gene            2297..3190
                     /gene="galF"
     CDS             2297..3190
                     /gene="galF"
                     /note="O037_02"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP-glucose-1-phosphate uridylyltransferase"
                     /protein_id="BAQ00841.1"
                     /translation="MTNLKAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMIQYIVDEIV
                     AAGIKEILLVTHASKNAVENHFDTSYELESLLEQRVKRQLLAEVQSICPPGVTIMNVRQ
                     GEPLGLGHSILCARPAIGDNPFVVVLPDVVIDDASADPLRYNLAAMIARFNETGRSQVL
                     AKRMPGDLSEYSVIQTKEPLDREGKVSRIVEFIEKPDQPQTLDSDIMAVGRYVLSADIW
                     PELERTQPGAWGRIQLTDAIAELAKKQSVDAMLMTGDSYDCGKKMGYMQAFVKYGLRNL
                     KEGAKFRKGIEKLLSE"
     CDS             6722..7777
                     /note="O037_06"
                     /codon_start=1
                     /transl_table=11
                     /product="putative UDP-glucose 4-epimerase"
                     /protein_id="BAQ00842.1"
                     /translation="MSILVTGGCGYIGIHTIFTLITQGHSVVVLDNLTNSSIEPLKRVE
                     LMANCNIPFYKGNVGDKRLLVEVFNKHQITAVIHFAGLKSVSESMKKPIEYYSNNVTQT
                     LSLLESMIDNNIKSFIFSSSATVYGKPNECPIKESHKIGNTTNPYGTSKFIMELMLSDL
                     CEAYNDLNITILRYFNPIGAHESGNIGEHPNGVPNNLFPYLMKVAIGEYPYLNVYGNDY
                     STYDGSGIRDYIHVVDLAEAHAKALSKNLVVDGLKIYNLGTGKGYSVFEVIETFEKITG
                     IKIPYRVMPRRDGDVAECWSNSLKANEELEWKATKDLSDMVRDAWNWQLKNPHGYDNDE
                     VMLLDSKMDDL"
     CDS             8301..8693
                     /note="O037_07"
                     /codon_start=1
                     /transl_table=11
                     /product="putative glycerol-3-phosphate cytidyltransferase"
                     /protein_id="BAQ00843.1"
                     /translation="MKKVITFGTFDVFHVGHINILERASKLGDYLIVGVSSDKLNFSKK
                     NRFPIYSEKDRVKIISSLRFVNEVFIEESLELKLEYIKKYNVDLLVMGDDWAGKFDWVK
                     SNCEVIYLPRTPSISTTEIIEIVRSI"
     gene            8695..9927
                     /gene="wzx"
     CDS             8695..9927
                     /gene="wzx"
                     /note="O037_08"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen flippase"
                     /protein_id="BAQ00844.1"
                     /translation="MFRRIISHRVFKNSFALFIMQLFSYVSPLLVLPYLARIMSVENFG
                     MLMMLYSLLAICLVVTDFGFNLSGTYYISRNYKNKKKINEFLTSVFCIKIILSTASVIF
                     FLVFFRGEFQRLDKYSVLLIAITMFVQSFQPIWFFQGIEKMRHITIYTALSKLIYLLLV
                     FLFVTSDSIVTVLLCYCISQMVGTFFSICFILKMKYSFSRTTYKNIISVFRQSIPFFVS
                     RVAVVVYTSANTLFLGKYGGMAQAASYSSCEKIYFAGQSLLNPLSQAFFPYLSKNRDAK
                     FYIKFVILSVCILSVICAVASFFVYDFLNIFYGQKYNDSIGILNTFLITTVIAYTSVSF
                     GYPMYTLIDKIGYVNHTVIIGAVIHIIGLFILAKENIFTAQNIAYLVLIVETSVLITRV
                     FLYTYLKIKRV"
     CDS             9927..10655
                     /note="O037_09"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="BAQ00845.1"
                     /translation="MELFNLINYSLYNSIIGRSYRKILRVFERNKNINKAQYGEMVVND
                     VMKLNYNYFPMFGTLLSLHRDGRFVFADDFDFAIIGDFPEDIISTFERNGYQLCALSLI
                     GNKREIIEYSFSKKIKNEYIKVDIFKLKEVNNIIRHSCPNFRKEKEFVRFRDGLKICQF
                     NSYFTVDYPKFDLTVSKWGIKIPNNPDDIFELHYGHDWEIPKTSNFIDFSAYRFIAERS
                     ETVLGPSEKLKEYIKNNMSC"
     gene            10658..11791
                     /gene="wzy"
     CDS             10658..11791
                     /gene="wzy"
                     /note="O037_10"
                     /codon_start=1
                     /transl_table=11
                     /product="GT2_Glycos_transf_2|GT2"
                     /protein_id="BAQ00846.1"
                     /translation="MIRLQNIILFVLLAFSGVYVSSWLIKPSYVAVIISFFILTILTLR
                     GVRYSFSSSIFILIAICVFYTIFNQFALEGELPTIIFYSCLILIPLLVSTFKSSTSKSN
                     ILLVSYIILIIYYSFETFIRITNPDYSHLPKTGDDGITSTFYIYKINSIAFEDSNFISV
                     ILVVYYISLRSTALYSDIKVKYSLGLNIGLLTLILLTFSRSAYIGVLIFECMVLFFFKP
                     DVNMKLRGLLVSIILVGGGICAHFIIEKIASDPSFISKFYIVDLTVKYLSHASTLDILF
                     GIGFGNAINVLGMGAHNIFIAIFIENGLIGTLLYLYILIMLSIRYKLTMLLIIPISIMG
                     LSFSQIAMPYFYVVIAWLIFVNEDRCEKISKCCNAHL"
     CDS             11778..12668
                     /note="O037_11"
                     /codon_start=1
                     /transl_table=11
                     /product="putative glycosyltransferase"
                     /protein_id="BAQ00847.1"
                     /translation="MPTYNNEKYIKSAIDDIMNQTYQYWELIIINDGSTDNTCQILSEY
                     NKVNNIHIINLVANKGICEALNVGLKIAKGDFILRFDADDRCSSDRISKLLEYMLKNNI
                     DIVGSSVITINENDDVIGKAVFSDNERIISRLIRYENPILHIWLAKREVYDKLGGYRIG
                     GVEDYDFILRALDSGYKVSNISDYFGISIRKHSRNTANTQGWRQRKCFNLAWTLHKERL
                     KKGYEVTSSIPRYGRFIKYGDKIHAISNKLLVKGISSKKLSYKIAIIVAAAVISPYQFQ
                     YLIYRFIGKIIKKTL"
     CDS             12665..13732
                     /note="O037_12"
                     /codon_start=1
                     /transl_table=11
                     /product="putative glycosyltransferase"
                     /protein_id="BAQ00848.1"
                     /translation="MKILYIIPSLKKCGPVNVCLSLAKNISENHSVSILAFRNGNSFND
                     FYSCCDNVKIIPIYNLFAIARFIAAEKFQIIHSHCLVPDFLLSLFSFFFRNKFIPISTI
                     HNYIDIDYIFSKGLFIGKLMGVINRLSLSKIKNLVSCSLAVKYYCDVAYDIRSTAISNG
                     VPISPYIDEMQQECNKKFIDFYYVGVLTERKNVDLLIQSFHLYKRKYKNEDRLHVIGGG
                     ELLEVLKKNNKCDYIIFYGPQVNPWPIIKSLDIYVSSSRAEGMPLALLEALSIGKAYIC
                     SNIEPHCEVHHVVNGGIICSFDKDDFVKAFHHMRYWDLKPKNEYILERFKNNYADYIMA
                     GKYLIKYEELLKEHE"
     CDS             13704..14540
                     /note="O037_13"
                     /codon_start=1
                     /transl_table=11
                     /product="putative glycosyltransferase"
                     /protein_id="BAQ00849.1"
                     /translation="MRSYSRNMNDIRFSVLMSLYKNESEKFLDDCFSSVYDQTLPANEI
                     TLVIDGPIPNSLEYVVLKWMVFLPINVVRLEKNVGLGQALNYGIKACSNDIIIRMDTDD
                     ICKRNRFEVLVKKLNSNNRLAVVGSCIEEFVHLPSNIISVRTVPLDPESIRKEILVRNP
                     FNHMSVAFRKKFIESVGGYVHHHFMEDYNLWLRVVASGFDVCNINESLILARVGDNMLA
                     RRKGLRYIKSEFQLYRLKVKLGLQSHISGFCILLVRSIPRLLPLKVLKIIYQYIRK"
     gene            14655..16061
                     /gene="gnd"
     CDS             14655..16061
                     /gene="gnd"
                     /note="O037_14"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphogluconate dehydrogenase"
                     /protein_id="BAQ00850.1"
                     /translation="MSKQQIGVVGMAVMGRNLALNIESRGYTVSIFNRSREKTEEVIAE
                     NPGKKLVPYYTVKEFVESLETPRRILLMVKAGAGTDAAIDSLKPYLNKGDIIIDGGNTF
                     FQDTIRRNRELSAEGFNFIGTGVSGGEEGALKGPSIMPGGQKEAYELVAPILTKIAAVA
                     EDGEPCVTYIGTDGAGHYVKMVHNGIEYGDMQLIAEAYSLLKGGLNLTNEELAQTFTEW
                     NNGELSSYLIDITKDIFTKKDEDGNYLVDVILDEAANKGTGKWTSQSALDLGEPLSLIT
                     ESVFARYISSLKEQRVAASKVLSGPQAQPAGDKGEFIEKVRRALYLGKIVSYAQGFSQL
                     RAASEEYNWDLNYGEIAKIFRAGCIIRAQFLQKITDAYAENPQIANLLLAPYFKQIADD
                     YQQALRDVVAYAVQNGIPVPTFAAAVAYYDSYRAAVLPANLIQAQRDYFGAHTYKRIDK
                     EGVFHTEWLD"
     gene            16310..17476
                     /gene="ugd"
     CDS             16310..17476
                     /gene="ugd"
                     /note="O037_15"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
                     /protein_id="BAQ00851.1"
                     /translation="MKITISGTGYVGLSNGLLIAQNHEVVALDILPSRVAMLNDRISPI
                     VDKEIQQFLQSDKIHFNATLDKNEAYRDADYVIIATPTDYDPKTNYFNTSSVESVIKDV
                     VEINPYAVMVIKSTVPVGFTAAMHKEYRTENIIFSPEFLREGKALYDNLHPSRIVIGER
                     SERAERFAALLQEGAIKQNIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYAESLG
                     LNTRQIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYQSVPNNLISAIVDANR
                     TRKDFIADAILSRKPQVVGIYRLIMKSGSDNFRASSIQGIMKRIKAKGVEVIIYEPVMK
                     EDTFFNSRLERDLATFKQQADVIISNRMAEELKDVADKVYTRDLFGSD"
     gene            17566..18600
                     /gene="wzz"
     CDS             17566..18600
                     /gene="wzz"
                     /note="O037_16"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen chain length determinant protein"
                     /protein_id="BAQ00852.1"
                     /translation="MAIIAKLWRLKIISSVRVMMRVENNNVSGQNHDPEQIDLIDLLVQ
                     LWRGKMTIIISVIVAIALAIGYLAVAKEKWTSTAIVTQPDVGQIAGYTNAMNVIYGSAV
                     PKVSDIQASLIGRYSTAFSALAETLDNQEEAEKLTIEPTVKNQSLPLAVSYVGETPEGA
                     QKQLAKYIQQVDDQVNEELEKDLKDNIALRMKNLQDSLKTQEVVAQEQKDLRIRQIQEA
                     LQYANQAQVTKPQVQQTEDVTQDTLFLLGSEALESMIKHEATRPLVFSPNYYQTRQNLL
                     DIESLKVDDLDIHAYRYVMKPMLPIRRDSPKKAITLILAVLLGGMVGAGIVLGRNALRN
                     YNAK"
     gene            complement(18772..>19104)
                     /gene="hisI"
     CDS             complement(18772..>19104)
                     /gene="hisI"
                     /codon_start=1
                     /transl_table=11
                     /protein_id="BAQ00853.1"
                     /translation="GPTXHKGTSSCFGDTAHQWLFLYQLEQLLAERKSADPETSYTAKL
                     YASGTKRIAQKVGEEGVETALAATVHDRFELTNEASDLMYHLLVLLQDQDLDLTTVIEN
                     LRKRHQ"
ORIGIN
        1 cgccatctta cgccagggat ttcataacca gattatcggt gccaacatca ccaactgtaa
       61 gttcagcgac ttacagggcg acgctattga atggaacgtg gcgattcacg acagtgatat
      121 tttgatatcc gaccatctca ttgagcgcat taactgtacc aacggcaaaa tcaactgggg
      181 catcggtata ggccttgcgg gaagtaccta cgataacaac tacccggaag accaggcagt
      241 gaaaaacttt gtcgtggcga atatcacggg atcggattgt cggcagttga tccatgttga
      301 aaatggtaaa cattttgtta ttcgtaatat caaagcccgc aatatcacgc cggatttcag
      361 taagaaagca ggtattgata acgccacggt tgctatttac ggttgtgata atttcgtgat
      421 tgataatatt gaaatgatta atagcgccgg gatgttaatc ggttatgggg taattaaagg
      481 caaatatctc tcgataccgc aaaatttccg ggtgaataat attcaactgg ataataccca
      541 ccttgcttac aaattgcgcg gtatccaaat ctctgccggg aatgccgtct cctttgtggc
      601 gctgactaac attgagatga agcgtgcgtc gctggagtta cacaacaaac cgcaacatct
      661 ttttatgcgt aatatcaagg tgatgcagga atcctctgtt ggacccgcat tgagcatgaa
      721 cttcgacatg cgcaaagacg ttcgcggcgt ctttatggcg aaaaaagaaa cactgctgtc
      781 tcttgcaaat gttcatgcgg tgaatgaaag agggcaaagc tccgtcgata tcgacaggat
      841 taatcaccat attgttaatg tggaaaagat taactttaga ttgccggaac ggagagagta
      901 gatttgcgac cattcataaa cttactggat ataatgttct aaaagattat aatcctcaca
      961 ctaactgtta aagctggggc tgggcagcat tgactactca gggaaggtac tcatctttat
     1021 cttgtgtttc ttacgtaaca accagactaa agtgatttat gaacgataac gttttgctca
     1081 taggagcttc cggattcgta ggaacccgac tacttgaaac ggcaattgct gactttaata
     1141 tcaagaacct ggacaaacag cagagccact tttatccaga aatcacacag attggcgatg
     1201 ttcgtgatca acaggcactc gaccaggcgt tagccggttt tgacactgtt gtactactgg
     1261 cagcggaaca ccgcgatgac gtcagcccta cttctctcta ttatgatgtc aacgttcagg
     1321 gtacccgcaa tgtgctggcg gccatggaaa aaaatggcgt taaaaatatc atctttacca
     1381 gttccgttgc tgtttatggt ttgaacaaac acaaccctga cgaaaaccat ccacacgatc
     1441 ctttcaacca ctacggcaaa agtaagtggc aggcggagga agtgctgcgt gaatggtata
     1501 acaaagcacc aacagaacgt tcattaacta tcatccgtcc taccgttatc ttcggtgaac
     1561 gcaaccgcgg taacgtctat aacttgctga aacagatcgc tggcggcaag tttatgatgg
     1621 tgggcgcagg gactaactat aagtccatgg cttatgttgg aaacattgtt gagtttatca
     1681 agtacaaact gaagaatgtt gccgcaggtt atgaggttta taactacgtt gataagccag
     1741 acctgaacat gaaccagttg gttgctgaag ttgaacaaag cctgaacaaa aagatccctt
     1801 ctatgcactt gccttaccca ctaggaatgc tgggtggata ttgctttgat atcctgagca
     1861 aaattacggg caaaaaatac gctgtcagct cagtgcgcgt gaaaaaattc tgcgcaacaa
     1921 cacagtttga cgcaacgaaa gtgcattctt caggttttgt ggcaccgtat acgctgtcgc
     1981 aaggtctgga tcgaacactg cagtatgaat tcgttcatgc caaaaaagac gacataacgt
     2041 ttgtttctga gtaatgcaga cgagtcagag aaaaaaggac caggttggac tacgattatt
     2101 cggaaagagg tactgattaa attatcagta tgcggaattc cgagtaatcc gagtaaccca
     2161 gatgctgatg gtgtgtagtg ttattctaag gtttaagcaa agttatgcgg aactaagctt
     2221 tggtatatag ccataacgtt tggctaacct atggcaataa tttacgcact atcagccact
     2281 tagaggtagg aaaagaatga cgaatttaaa agcagttata ccggtagcag gtcttgggat
     2341 gcatatgttg cctgccacta aggcgattcc caaagagatg ctaccgatcg tcgacaagcc
     2401 aatgattcag tacattgttg acgagattgt ggctgcaggg atcaaagaaa tcctcctggt
     2461 aactcacgcg tccaagaacg cagtcgaaaa ccacttcgac acctcttatg aattagaatc
     2521 tctccttgaa cagcgcgtga agcgtcaact gctggcggaa gtacagtcta tctgtccgcc
     2581 gggcgtgacc attatgaacg tgcgtcaggg cgaaccttta ggtttaggcc actccatttt
     2641 gtgtgcacga cccgccattg gtgacaaccc atttgtcgtg gtattgccgg acgttgtgat
     2701 cgacgacgcc agtgccgacc cgctgcgcta caaccttgct gccatgattg cacgtttcaa
     2761 cgaaacgggc cgcagccagg tgctggcaaa acgtatgccg ggtgacctct ctgaatactc
     2821 cgtcattcag actaaagagc cgctggatcg tgaaggtaaa gtcagccgta ttgttgaatt
     2881 catagaaaag ccggatcagc cgcagacgct ggactcagac atcatggccg ttggtcgata
     2941 tgtgctttct gccgatattt ggccggaact tgaacgcact cagcctggtg catgggggcg
     3001 tattcagctg actgatgcca ttgccgaact ggcgaaaaaa cagtccgttg atgccatgct
     3061 gatgactggt gacagctatg actgcggtaa aaaaatgggt tatatgcagg cgtttgtgaa
     3121 gtatggactg cgcaacctca aagaaggggc gaagttccgc aaaggcattg agaaactgtt
     3181 aagcgaataa tgaaaatctg accgaatgtg acggttggca aggaaactat aacagcagtg
     3241 aagattcgtg gcgaaagtaa tttgttgcga atattcctgc cgttattttg tataaacaat
     3301 cagaataaca aatagttagc aataggcttt tcgtcaaagt tttcctggat tttccttgtt
     3361 tccagaacgg attggtaaga caattagcgt atgaattttt cgggtttggc gcgagtgggt
     3421 aacgctcgcc acatcgtagg catgcatgca gtgctctggt agctgtaaag ccaggggcgg
     3481 tagcgttcag tgaaatatta cgtgatgctg cagtgtactt aataattcgt aaactatgtt
     3541 caaggattga tgcgtccctt atcgtctaaa tcgtctttca caacttatat atggttgaat
     3601 acctattata taaataagtt agagaattga tggacatatt tcttttatcc cccgattaaa
     3661 gacaagccta ggaagtagaa catatattgt ctgatattct actgttgact atttgcaccg
     3721 ttattttggt acagaaggtt gggaagatat agaggatttt gggaaaacac ctctcgattt
     3781 tttgaagcaa tatggtgatt ttgaaaatgg tattcctgtt cacgatacca ttgctagagt
     3841 tgtatcctgt atcagtcctg caaaatttcg cgaatgcttt attaactgga tgcgtgactg
     3901 tcattcatca gatgataaag atgtcatcgc aattgattga aaaacactcc gctattctta
     3961 tggtaagagt cgccgcaggg gagcgattca tgtcattggt gtgttctcaa caatgcacag
     4021 tctggtcatc ggacagatca aggcggataa gaaatccaat gagagtgtgc cgtgggggtt
     4081 gaaactagcc tgcttggata acagtcagtg gtgaacataa gcttgtgaag agaaggaggt
     4141 cggccttcca gagtcgatgg tcggaggttg actctaaacc cccttcaggt ggctgtcatt
     4201 aagagtgatg gtcagaagcg ttgaagggaa atcagaataa gattctggcg aggtaagatg
     4261 taaggagagg agtaaccccg aacctgtgtt gacacgtcgt tatctttaaa atggcatcgg
     4321 aactgaggtc gtctcgttat ctctggataa gcacactggc gaagtccgaa tgttgagtgt
     4381 gcggtgtccg gcgtaaagca ggcatgacct tatatcaggc tctttgtagt aaccacggga
     4441 accagtcatc atgatgttaa ggaagaaagg taaatcaccg aaatgataag cctgtgagta
     4501 ccgaagcatg atactggggc ggagcaactt gtagcagtga ggaagcattt gtaatgagtg
     4561 tggaacgaag ggagggcgtt aagcagtctg aaccggcatc tcaactgtca caatgtggca
     4621 ggaggaaggc gtgcgggcag gcaaaaccat ttgcgatcta aaaatgggaa gtgcaggccg
     4681 cgtttgataa agtgaaagcg aatcaaggcg gggcgggtat tgatggtgta acgcttgaga
     4741 tgtttgaaag aaatcttaat aacaacctgt ataagatatg gaatcgtcta tcatttgaaa
     4801 cgtattttgc tccgtcagta aaagcggtca atataccgaa gaaaacaggt ggagtaagag
     4861 cgttaggtat tccgacggtt gtgatcgggt agcgcagatg gtgattaaag agcgacttga
     4921 ggcaataata gaaccctgtt ttctgagtga ttcctatggt tacagatcgg caaaatcagc
     4981 gattcaggct attggtgtaa caagaaaacg ctgttgggaa tataattgga ttctgtagtt
     5041 tgatatcaaa ggtctgtttg ataatatacg gcatgattta ctgcttaaag cagttgaaaa
     5101 acatgttgct aatggttctc aaattcaagg gcaagagctg agtttgctca ccttctatat
     5161 aaaacgatgg ttagtttcac cattgcagca ggatgacggg aatattatct tgcgagattg
     5221 gggacaccac aagggggctt agtcagctca cttctggcga atttattttc acactatgtt
     5281 tttgataaat ggatgcagag agaatttccc gaaaatccgt ggtgtcgata tgcagatgat
     5341 ggactggttc atgctatcac taaaggcaaa gcagaatcac tgtatgaaag gataaaacgc
     5401 cgtttggaag agtgtggtct cgaattacat ccagaaaaga cgaaaataat atattgtaag
     5461 gacgataaaa gaaagtgaac atgtgttcac actagcttcg attttatggg atatacattc
     5521 agacaaagaa gatgtaggaa atgctcacat aatacattct tcaatagctt tattccggca
     5581 gtgggtatga tgaagaaatg agacggagga gcagggagct gaaaatcagg caaaagagcc
     5641 actatagttt agaagaacta tcacgttggt taaacccaat agtgcaggga tggataagct
     5701 attatggtca atattgtcgg tcggttctcg atcctgtatt tcgacatatc aataaaacgc
     5761 tggtgcgttg ggcaagaagg aaattcaaga cgctaaagag gcacaaaagt agaacgatag
     5821 gtctgtttga cagattatcg gtaaagtctt ccaaactatt cgctcactgg cgatttggct
     5881 cagtaagaac gtttgcttaa tggaagcgga atgaattgag aggttcacgt tccattttgc
     5941 gagaggctag aggggaagtt cctccggtct actcacctca cagctattta agagcttctt
     6001 aacatattgg ggattaaaga aaaaattatc acaactgatg cgatggggtg ccagaaagat
     6061 attgcagaga aggtacaaaa cagggaggtg attatttatt cgctgtaaaa gaaaatcagg
     6121 ggcagcttaa taaagcctcg aggaaaagtt tcagctgaaa gacttgaatg atccaaagca
     6181 tgacagttac gcaattagtg aaaagagtca cggcagagaa aaaatccgtc ttcacattgt
     6241 ttgcgatgtc cctgatgaac ttattgattt cacgtttgaa tggaaaggac tgaaaaaatt
     6301 atgcgtggca gtctcctttc ggtcaataat agcagaacaa aagaaagagc cagaaatggc
     6361 ggtcggatat tatatcagtt ctcctgattt accgcagaga agttcgccac agcgattcga
     6421 aattactggc accagaaagt gataatgagt gaagatgacc gcaaaataag aagaggaaac
     6481 gaagcggaat tatttttagg gatacggcgc atctctatta atattttgac gaatgaaaag
     6541 atattcaagg cagggctaag acgtaagaca cgaaaagcag tcatggacag aaactatcta
     6601 gcgtcagtcc ttgtgggtaa cgggatttcg taatcttgtt ctgactgcta taaagacctt
     6661 atgagttctt aaaaagcatt ttttgccaag agtaaattat tgactatcga ttggagagtg
     6721 tatgtctatt ttggttactg gtgggtgtgg atatattgga atccacacga tttttactct
     6781 gattacccaa ggtcatagtg ttgttgtatt agataactta actaactcat ctatagaacc
     6841 attgaagaga gttgagttga tggcaaattg taatatacct ttctacaaag gaaatgttgg
     6901 ggataaaagg ctattagtag aagtatttaa taagcatcag attactgctg taattcattt
     6961 tgcaggattg aaatcagtaa gtgaatctat gaaaaaacca attgaatatt attctaacaa
     7021 tgttacacaa acattatctc tgttagagtc gatgatagat aataatatca aaagttttat
     7081 ctttagttcc tctgctactg tatatggtaa accaaatgaa tgtcctataa aagaatcaca
     7141 taaaattggt aatacgacaa atccttatgg aacttcaaag tttataatgg aattaatgtt
     7201 gtcagatttg tgtgaggcat ataatgatct aaatataact attttacgat attttaatcc
     7261 aataggtgct catgagtcag gtaatatagg tgaacatcca aatggggttc caaataatct
     7321 ttttccttat ctcatgaagg tagctatagg agagtatcca tatttaaatg tgtatggaaa
     7381 tgattactca acatatgatg gttctggtat acgtgattat atccatgtcg tggatcttgc
     7441 agaagctcat gccaaagcat tatcaaaaaa tttagtggta gatggtttaa aaatttataa
     7501 cttaggaaca gggaaaggtt attctgtatt tgaagttata gaaacttttg aaaaaataac
     7561 agggataaag attccatata gagttatgcc ccggagagat ggggacgtcg cagaatgttg
     7621 gtcaaatagt ttgaaggcaa atgaagaatt agaatggaaa gcaacaaaag atttatctga
     7681 tatggtaaga gatgcttgga attggcaatt gaaaaatcct catggttatg acaacgatga
     7741 agtaatgctc ttagatagta aaatggatga tttgtaaatg cgatttaagt ttagtactat
     7801 gaggtgtggg ggagagggga tgactgatgt tctttattag aaaaatttac ttatcagtgg
     7861 tcagtttttc tgtataaaga gtttatacag agtgagtaat ttttgattgg tttatcgacg
     7921 cggggtataa cagtataagt ttcgcgtcta tttatattcg gattatattc atactgaagc
     7981 cagattttat agaggagtta ttgataaatt tctattgata gttgaatata taaatacaat
     8041 gttgatatgg ggttatgttt attatatttg gatgagaagc aggggcattg taagtgaatc
     8101 ttaggcaaga ataatataca gtatgatcat atcatcagct tgttgaaaaa tacatgattt
     8161 atcagtacat aaaaatatat cttgtaactt ttattgatta aaatggaaag gcaaatttat
     8221 aatatgctag ttaggtagtg aagacaattg aaacaagaaa cgttaaattt ataaagttta
     8281 ttcgattatt aggatgcata atgaaaaaag taataacttt tggtacattt gatgtatttc
     8341 acgttggaca tataaatatt ttagagcgag cgtctaaact cggagattat ttgatcgttg
     8401 gagtatcttc cgacaaactt aactttagta aaaaaaatcg ttttccaatt tatagtgaga
     8461 aggacagggt aaaaataatt tcatctttaa ggtttgttaa tgaggttttt attgaggaat
     8521 cgttagaact taaactggag tatattaaaa aatataatgt agacctgctg gttatgggag
     8581 atgactgggc tggaaaattc gattgggtta aatcaaactg tgaagttatt tatttgccta
     8641 gaacaccatc tatttcaaca acagaaatta ttgagatagt aaggtctatt tgaaatgttt
     8701 aggaggataa tttcacatag ggtgtttaag aattcatttg cattatttat catgcagtta
     8761 ttttcatatg tttcaccatt attggttctt ccatatctgg ctaggatcat gtctgtagaa
     8821 aactttggca tgctaatgat gctgtattct ttattagcca tatgccttgt cgtgactgat
     8881 tttggtttta atttatcagg aacttactat atatcaagaa attataaaaa taaaaaaaag
     8941 ataaatgagt ttttaacatc tgttttttgc attaaaataa tattatctac tgcatcagta
     9001 atattttttc tggttttttt taggggggag tttcaacgtt tggataaata ctccgtgctt
     9061 ttaattgcaa ttacaatgtt tgttcagtct tttcaaccta tatggttctt ccagggtata
     9121 gaaaagatga ggcatataac tatatatacg gcactgtcaa aactgattta tcttttatta
     9181 gtgtttttgt tcgttaccag cgattcaatt gtcacggtat tactatgcta ctgtataagt
     9241 caaatggtag gaactttttt ttcaatttgt tttattttga aaatgaaata ttcgttttct
     9301 cgaaccacat ataaaaatat aatttctgtt ttcagacaaa gtattccttt ttttgtgtca
     9361 agagttgctg tggttgttta tacatctgca aatacacttt ttcttgggaa atatgggggt
     9421 atggcgcagg ctgctagtta tagcagttgc gaaaaaatat attttgcagg gcaaagtttg
     9481 ttaaacccgt tatcacaggc atttttccct tatttgtcta aaaatagaga tgcaaaattt
     9541 tacattaaat ttgtaatatt gtcggtttgt attttgtcag ttatttgtgc agtggcatct
     9601 ttttttgttt atgatttttt gaatattttt tatggccaaa aatacaatga ttcaattggc
     9661 atattaaata catttctcat aacaactgtt attgcttata cgtcagtcag ttttggatat
     9721 cctatgtata cccttattga taaaatagga tatgtaaatc acactgtaat tatcggagca
     9781 gtgatacata tcataggact atttatatta gcaaaggaaa atatatttac agctcaaaat
     9841 attgcttatt tagttttaat agtagaaaca tcagtgctaa ttacaagagt ttttctttat
     9901 acatatctaa agattaagag ggtgtaatgg aattatttaa tttaatcaat tattcgctgt
     9961 ataatagtat tattggtcga agttatagaa aaatccttag ggtatttgaa agaaataaaa
    10021 acattaataa ggcacagtat ggggaaatgg ttgttaatga cgtgatgaaa ttgaactata
    10081 attattttcc tatgtttggt acgttattat cgttgcatag agatgggagg tttgtatttg
    10141 ccgatgattt cgattttgca attattggcg attttccaga ggatattatt tcaacctttg
    10201 aaagaaatgg ttatcaatta tgcgctttat ctttgatagg aaacaaacgt gaaattattg
    10261 agtattcttt tagtaaaaag ataaaaaatg aatatataaa ggttgatatc tttaaattaa
    10321 aagaggtgaa taatattata cgacatagtt gtcctaattt tagaaaagaa aaggagtttg
    10381 tgagatttcg agatggtctt aaaatatgcc agttcaatag ttattttact gttgattatc
    10441 ctaagttcga tttaactgtc agcaaatggg ggataaaaat accaaataat cctgatgata
    10501 tatttgaact tcattatggt catgattggg aaatacctaa aacatcaaac tttattgatt
    10561 ttagtgcgta tcgctttatt gcagaaagat cggaaactgt actcggacca agtgagaaac
    10621 ttaaagaata tattaaaaat aatatgagtt gttgatgatg attagattgc aaaatattat
    10681 tttatttgta ttactagcat tttctggagt ttatgtatca tcttggttga ttaaacctag
    10741 ttatgtcgca gttatcattt cattttttat cttaacgata ttaactttac gtggtgttag
    10801 gtattcgttt tcatcatcta tttttatctt gatagcaatt tgcgtatttt atacaatatt
    10861 taatcaattc gcccttgaag gagaattgcc aacaattatt ttttactcat gcctgatatt
    10921 aattccattg cttgtatcaa catttaagag ttcaacatcc aaaagtaaca tacttctagt
    10981 ttcatacata atattaataa tatattactc ttttgaaact ttcataagga ttactaaccc
    11041 agattatagt catttgccta aaacaggtga tgatggtata acgtcaacat tctatattta
    11101 taaaattaat agtattgctt ttgaagattc taactttatc agtgttattc ttgtggttta
    11161 ttatatttca ttaaggagta cggctcttta tagcgatatt aaagttaaat atagtttggg
    11221 actaaatatt ggtctgctaa ctttgatttt attaaccttc tcaagatctg catatatagg
    11281 tgtgcttatt tttgaatgca tggttttatt cttttttaag cctgatgtta atatgaaatt
    11341 acgtgggttg ttagtatcaa taatattggt aggtggtggt atatgtgctc atttcattat
    11401 tgagaagatt gcttctgatc cgagttttat aagtaaattt tatattgttg atcttactgt
    11461 aaagtattta agtcatgcgt caactttaga cattttattt ggtataggat tcggcaatgc
    11521 tatcaatgtt cttggaatgg gagcgcataa tatattcata gcgattttca tagaaaatgg
    11581 cttgatagga acattattat acttatacat attaattatg ctttcaatac ggtataagtt
    11641 aactatgtta ttaattattc caattagtat catggggtta tctttttcgc aaatagcaat
    11701 gccgtatttt tatgtagtta ttgcatggct gatttttgta aatgaggaca gatgtgaaaa
    11761 aattagtaag tgttgtaatg cccacttata ataatgagaa atatattaag tctgcaatag
    11821 atgatattat gaatcaaact tatcagtatt gggagttaat aataattaat gatggttcaa
    11881 cagataacac ctgccaaatt ttatcagaat acaacaaggt taataatata catattatta
    11941 accttgttgc taataaagga atttgtgaag cattaaatgt tggtttaaag attgctaagg
    12001 gagattttat cctcaggttt gacgcagatg atagatgttc tagtgataga ataagtaaat
    12061 tacttgaata catgttaaag aataatattg atatagtagg aagctctgta attactataa
    12121 acgaaaatga tgatgtaatt ggtaaagccg tttttagtga taacgagagg attataagcc
    12181 gtttaataag atatgaaaac cctatattac acatttggct ggcaaaaaga gaagtatatg
    12241 ataaattagg agggtatagg ataggaggag tggaagacta tgattttatt ctacgagctc
    12301 tagactctgg ttacaaggta tctaatatca gcgattattt tggtatttct attcgaaaac
    12361 atagtagaaa tactgcgaat actcaaggat ggaggcaacg taaatgtttt aatttggctt
    12421 ggacgttaca taaggaaagg ttgaaaaaag gttatgaagt tacaagcagc ataccaagat
    12481 atggacgttt tatcaaatat ggtgataaaa tccacgccat atctaataaa ttattagtta
    12541 aggggatttc ttcaaaaaaa ttatcctata agatagcgat aatagtagct gctgctgtta
    12601 tttccccata tcagtttcaa tatttaattt atcgattcat tggcaagata ataaaaaaga
    12661 ctctatgaaa atactttaca tcataccaag tttaaaaaaa tgtgggccag taaatgtttg
    12721 cttatcattg gcaaaaaata tctcggaaaa tcatagtgtt tctatattgg cttttcgcaa
    12781 tggaaattcc tttaatgatt tttattcttg ctgtgataat gttaagataa taccaattta
    12841 taatcttttt gccatagcaa gatttattgc tgccgagaaa tttcagatta tccattcgca
    12901 ttgtttggta cctgattttt tattatcttt gtttagcttc tttttcagga ataaatttat
    12961 cccaatatcg acaatacata attatattga tattgattat attttcagta aaggactttt
    13021 tataggtaag ttgatgggag tcattaatcg gctttcatta agtaaaatta agaacttagt
    13081 ttcatgttct ttagctgtta aatattattg tgatgttgct tatgatataa gaagtactgc
    13141 aattagtaac ggagttccta tttctccata tatagatgag atgcaacaag aatgcaataa
    13201 aaaatttatt gatttttatt atgttggtgt tctgacagaa cgcaaaaatg ttgacttact
    13261 catacagtca tttcatttat ataaaagaaa atataaaaat gaagaccgat tgcatgtgat
    13321 tggcggaggg gagttgttgg aagttttaaa aaaaaataac aagtgcgatt atattatttt
    13381 ttatggccct caagtaaatc catggcctat tattaaatct ttagacattt atgtgagtag
    13441 ctctagagct gaagggatgc cgttggcatt attagaagcg ttatcaatag gaaaggcata
    13501 tatttgttca aatattgaac cgcactgtga ggtccatcat gttgttaatg gtggtattat
    13561 ttgctccttt gataaagatg attttgttaa agcttttcat catatgagat attgggatct
    13621 aaaaccaaaa aatgagtata ttcttgagag gtttaagaat aattatgcag attatataat
    13681 ggctgggaaa tatctgatta agtatgagga gttactcaag gaacatgaat gacataaggt
    13741 tttctgtgtt aatgtctcta tataaaaatg agtctgaaaa attcttggat gattgttttt
    13801 ctagcgtata tgatcagacg ttacctgcta atgagataac tctggtaatt gatggcccaa
    13861 ttcccaattc acttgaatat gttgtgttaa aatggatggt ttttttacct ataaatgtgg
    13921 ttagacttga aaaaaatgtt ggattgggcc aagcattaaa ctatggaatt aaagcttgtt
    13981 caaatgatat tattataaga atggatactg atgatatttg taaaagaaac agatttgaag
    14041 ttttagtaaa aaaattgaat tcaaataata ggttagctgt agtcggctct tgtatcgaag
    14101 agtttgttca tcttccaagt aatattatct cagtaagaac tgttccacta gatcctgaat
    14161 ccataaggaa agaaatctta gttagaaatc ctttcaatca tatgtctgtt gcattcagaa
    14221 aaaaatttat tgaaagcgtt ggtggatatg tccatcatca ttttatggaa gattataatc
    14281 tttggttacg agtagtggca tctggatttg atgtgtgtaa cattaatgag tcgttaatat
    14341 tagctagagt tggtgataat atgttggcta ggcgaaaagg gctgaggtat ataaaaagtg
    14401 aattccaact ttatcggcta aaagttaaac ttggtttgca gtcacatata tctggattct
    14461 gcattttgtt agtaagaagc attccgcgat tactccctct aaaggtctta aaaattattt
    14521 accaatatat tcggaagtaa ttatataata attctgaaga ttgcactctt attttttctt
    14581 agttgtatct ttgtatgtta acattacgtt taaaccgaac cgctaagacg gtaatttcgt
    14641 gacaggagta aacaatgtca aagcaacaga tcggcgtcgt cggtatggca gtgatggggc
    14701 gcaaccttgc gctcaacatc gaaagccgtg gttataccgt ctctattttc aaccgttccc
    14761 gtgaaaagac ggaagaagtg attgccgaaa atccaggcaa gaaactggtt ccttactata
    14821 cggtcaaaga gtttgttgaa tctctggaaa cgcctcgtcg catcctgtta atggtgaaag
    14881 caggtgcagg cacggatgct gctattgatt ccctcaagcc atacctcaat aaaggtgaca
    14941 tcattattga tggtggtaat accttcttcc aggacaccat tcgtcgtaac cgtgagcttt
    15001 ctgccgaagg ttttaacttc atcggtaccg gtgtttccgg cggtgaagag ggggcgctga
    15061 aagggccttc catcatgcct ggtgggcaga aagaagccta tgaactggtt gcgccgatcc
    15121 tgaccaaaat cgccgccgtt gctgaagatg gcgaaccgtg cgttacctat attggtaccg
    15181 atggcgcagg tcactatgtg aagatggttc acaacggtat tgaatatggc gatatgcagc
    15241 tgattgctga agcctattct ctgcttaaag gtggcctgaa cctcaccaac gaagaactgg
    15301 cgcagacctt taccgagtgg aataacggtg aactgagtag ctacctgatc gacatcacca
    15361 aagacatctt caccaaaaaa gatgaagacg gtaactacct ggttgatgtg attctggatg
    15421 aagcagcaaa caaaggtacc ggtaaatgga ccagccagag cgcgctggat ctcggcgaac
    15481 cgctgtcgct gattaccgag tctgtgtttg cacgttatat ctcttctctg aaagagcagc
    15541 gtgttgccgc atctaaagtt ctctctggcc cgcaagcgca gccagctggc gacaaaggtg
    15601 agttcatcga aaaagttcgt cgtgctctgt atctgggcaa aatcgtttct tacgctcagg
    15661 gcttctctca gctgcgtgct gcgtctgaag agtacaactg ggatctgaac tacggcgaaa
    15721 tcgcgaaaat tttccgtgct ggctgcatca tccgtgcgca gttcctgcag aaaatcaccg
    15781 atgcttatgc cgaaaatccg cagatcgcta acctgctgct ggctccgtac ttcaagcaaa
    15841 ttgccgatga ctaccagcag gcgctgcgtg atgtcgttgc ttatgcagta cagaacggta
    15901 tcccggttcc gaccttcgcc gctgcggttg cctattacga tagctaccgt gccgctgttc
    15961 tgcctgcgaa cctgatccag gcacagcgtg actatttcgg tgcacatact tataagcgca
    16021 ttgataaaga aggtgtgttc catactgaat ggctggatta atctgattta accaacaata
    16081 aaattgaggc ccggcgtata ttgcaccggg cttttttttg ccaattatct tatagactaa
    16141 atttcactgc ttaatattaa cttaataaat atcagctatt cttataaaga aaatctgaat
    16201 tgtttttcgt tgcgttgacc atctgacaac gtagcgttaa aacttttagc tctaatcagg
    16261 atgctaaaaa catcatgatt cacagttaag ttaattctga gagcatgaaa tgaaaatcac
    16321 catttccggt actggctatg taggcttgtc aaacgggctt ctaatcgcac aaaatcatga
    16381 ggttgtggca ttagatattt taccgtcacg cgttgctatg ctgaatgatc ggatatctcc
    16441 tattgttgat aaagaaattc agcagttttt gcaatcagat aaaatacact ttaatgccac
    16501 attagataaa aatgaagcct accgggatgc tgattatgtc atcatcgcca ctccaaccga
    16561 ctatgatcct aaaactaatt atttcaatac atccagtgta gaatcagtaa ttaaagacgt
    16621 agttgagata aacccttatg cggttatggt catcaaatca acggttcccg ttggttttac
    16681 cgcagcgatg cataaggaat atcgtactga aaatattatt ttctctccgg aatttctccg
    16741 tgaaggtaaa gctctttacg ataatctcca tccttcacgt attgtcattg gtgagcgttc
    16801 agaacgcgca gaacgttttg ctgctctgtt acaggaaggc gcgattaagc aaaatatccc
    16861 gaccctgttc accgattcaa ccgaagcaga agcgattaaa ctgtttgcta atacctatct
    16921 ggcgatgcgc gtagcatact ttaatgaact ggatagctat gcagaaagtt taggtctgaa
    16981 tactcgtcag attatcgaag gtgtttgtct cgatccgcgt attggcaacc attacaacaa
    17041 tccgtcgttt ggttatggtg gctattgttt gccgaaagat accaagcagt tactggcgaa
    17101 ctaccagtct gtgccgaata acctgatctc ggcaattgtc gatgcaaacc gcacgcgtaa
    17161 agattttatt gccgatgcca ttttgtcacg caaaccgcaa gtggtgggta tttatcgtct
    17221 gattatgaag agcggttcag ataacttccg tgcgtcttcc attcagggaa ttatgaaacg
    17281 tatcaaggcg aaaggtgttg aagtaatcat ctacgagccg gtgatgaaag aagacacatt
    17341 cttcaactct cgtctggaac gcgatctcgc caccttcaaa caacaagccg acgtcattat
    17401 ttccaaccga atggcagaag agcttaagga tgtggcagat aaagtctaca cccgcgatct
    17461 ctttggtagc gactaacatc ttgttatcag ggcgattttc gccctgattc tcttatgttc
    17521 cctttgtaat aattcattat ttttatcatt tatcctatag cattcatggc gattatcgct
    17581 aaactatggc gacttaaaat tatttcgtcc gttagggtaa tgatgagagt agaaaataat
    17641 aatgtttctg ggcaaaacca tgacccggaa cagattgatt tgattgattt actggtccaa
    17701 ctatggcgcg gcaagatgac tatcatcatt tctgtcattg tggctattgc cctggctata
    17761 gggtatctgg ccgttgccaa agaaaagtgg acttccacag ctatcgttac tcaacctgat
    17821 gtggggcaaa tcgctggtta taccaacgcg atgaatgtga tctacggatc agctgtaccg
    17881 aaagtctccg acattcaggc ttcacttatc ggacgttaca gcactgcatt ctcagcatta
    17941 gcggaaacgc tggataacca ggaagaagca gaaaagctga ccattgagcc taccgttaaa
    18001 aatcagtcat taccgttagc ggtttcttat gtgggtgaaa cacctgaagg tgcgcagaaa
    18061 cagctggcga agtatatcca gcaagttgac gaccaggtca atgaagaact ggaaaaagac
    18121 ctgaaagata acatcgcgct gcgtatgaaa aacttgcagg actctctgaa aacccaggaa
    18181 gtggtcgcgc aggagcagaa agatctgcgt atccgtcaga ttcaggaagc gttgcagtat
    18241 gcgaatcagg cgcaggtgac aaagccacaa gttcagcaga ctgaagatgt gacacaagat
    18301 acgttgttcc ttttggggag cgaagcgctg gagtcgatga ttaagcatga ggcgacccgt
    18361 ccgttggtgt tctcgccaaa ctactatcag actcgtcaaa acctgctgga tatcgaaagc
    18421 ttaaaggttg atgatcttga tattcatgct taccgttatg tgatgaaacc gatgttacct
    18481 attcgtcgcg atagcccgaa aaaggcaatt accttgattc tggcggtgct gctgggcggc
    18541 atggttggcg cggggattgt gctggggcgt aatgcgctgc gtaattacaa cgcgaaataa
    18601 tctttgcagc tttaaagaaa acgggcaggg tggtgacacc ttgcccgttt tttttgccgg
    18661 atgcgatgta tccagcttac gtgtgcagag agaatagtcg gcccgataag cttgcgcatc
    18721 gggctatggc tccggatgcg acaacaacat cgcatccgct tacccagtaa ctcactgatg
    18781 ccgtttacgc aggttctcaa ttaccgtcgt taaatccaga tcctgatcct gcaacagcac
    18841 cagcaggtga tacatcaaat cagatgcctc gttggtcagc tcaaagcggt catgtaccgt
    18901 tgctgccagt gcggtttcca cgccttcttc gcccactttc tgcgcaatgc gtttggtgcc
    18961 gctggcatac agtttggcag tgtaggaggt ttccgggtcg gcagatttac gttcggcgag
    19021 cagttgttcc agttgataca ggaacagcca ctggtgagcg gtgtcgccga agcagctgct
    19081 ggtgcctttg tggmaggttg gccc
//
