y
Basic Information | |
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Species | Ricinus communis |
Cazyme ID | 29794.m003378 |
Family | GT47 |
Protein Properties | Length: 601 Molecular Weight: 68872.8 Isoelectric Point: 7.8992 |
Chromosome | Chromosome/Scaffold: 29794 Start: 444734 End: 447400 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 474 | 552 | 1.8e-36 |
ARGKMNYVQHMKSSRYCICARGYEVNSPRIVEAILYECVPVIISDNYVPPFFEVLNWESFAVFVLEKDIPNLKNILLSI | |||
GT47 | 323 | 474 | 2.29995e-41 |
ENLKVYIYKEGEKPILHQPVLKGIYASEGWFMKQLEASKKFVTKKSRKAHLFYLPFSSRNLELQLYVPDSHSRKNLIKYLKNYLDLIVAKYPFWNRTEGV DHFLVACHDWAASETEQLMFNCIRALCNADVKEGFIFGKDASLPETNSDAKA |
Full Sequence |
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Protein Sequence Length: 601 Download |
MGQDFRYQCP VETWRLLWFL GIMFVVIMAF QHFELPSGYI LSSISSVHSN QIAENGSVST 60 IGALSKPEIV SNMTHLNAVN PKDADDSHGH GREKHPDVNN DFASDTSVVS NNSSLIDNHD 120 KESSIQQAVQ PTVRSTADPL RTSGNRYVPE ETGLSKNPRI SDSGIAPFMP VLPPEVSSSN 180 MTFPMNVESN MVTPVVDVDS NTSAVEKYET PILANHGKSG ELKNKITRLY DNSSSAPNSY 240 LKKTPETQTS GVISVMEMNN LLLQSWSSPM MRSPRWASPV DQELLQAKSQ IENAPIIKND 300 PKLYAHLYWN LSMFKRSYEI MEENLKVYIY KEGEKPILHQ PVLKGIYASE GWFMKQLEAS 360 KKFVTKKSRK AHLFYLPFSS RNLELQLYVP DSHSRKNLIK YLKNYLDLIV AKYPFWNRTE 420 GVDHFLVACH DWAASETEQL MFNCIRALCN ADVKEGFIFG KDASLPETNS DAKARGKMNY 480 VQHMKSSRYC ICARGYEVNS PRIVEAILYE CVPVIISDNY VPPFFEVLNW ESFAVFVLEK 540 DIPNLKNILL SIPEKRYREM QMRVKMVQQH FLWHARPVKY DLFHMILHSV WYNRVFQMHP 600 R 660 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 5.0e-53 | 321 | 552 | 301 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_195005.1 | 0 | 5 | 598 | 23 | 593 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002281263.1 | 0 | 1 | 601 | 1 | 669 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002309547.1 | 0 | 185 | 601 | 1 | 471 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002324801.1 | 0 | 258 | 601 | 1 | 398 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002516499.1 | 0 | 1 | 601 | 1 | 601 | catalytic, putative [Ricinus communis] |