Basic Information | |
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Species | Ricinus communis |
Cazyme ID | 32250.m000015 |
Family | GH43 |
Protein Properties | Length: 495 Molecular Weight: 54205 Isoelectric Point: 6.7443 |
Chromosome | Chromosome/Scaffold: 32250 Start: 45 End: 1529 |
Description | |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GH43 | 57 | 350 | 0 |
VNPILSGYYPDPSITRVGDDYYLVNSSFTNFPGLPVFRSRDLVNWTQVGNALDRPGQVDFTGVRASQGIYAPDISYHDGTYYIVTTCSSCPGGTGNFVIT AKDPAGPWSQPVTIRGLQGIDPSLVWEDDKLYVVYNNAPEGQPRYEGHRAIWMAELDPRTLQFAGKPKVIVDGGVVPANRPIWIEGPHIFRKDGHYYLIC AEGGTADNHSEVVFRADAVTGPYVPGPVNPILTQRDLDPKRAHPVTTAGHADFVQTQNGQWWAVFLATRPYPGNFYNIGRETFMLPVDWKDGWP |
Full Sequence |
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Protein Sequence Length: 495 Download |
MKNHSVRSMV LWGVFALGAA SSMAAADGRS TTVARFERFS YQGQAQETVR PRDGEFVNPI 60 LSGYYPDPSI TRVGDDYYLV NSSFTNFPGL PVFRSRDLVN WTQVGNALDR PGQVDFTGVR 120 ASQGIYAPDI SYHDGTYYIV TTCSSCPGGT GNFVITAKDP AGPWSQPVTI RGLQGIDPSL 180 VWEDDKLYVV YNNAPEGQPR YEGHRAIWMA ELDPRTLQFA GKPKVIVDGG VVPANRPIWI 240 EGPHIFRKDG HYYLICAEGG TADNHSEVVF RADAVTGPYV PGPVNPILTQ RDLDPKRAHP 300 VTTAGHADFV QTQNGQWWAV FLATRPYPGN FYNIGRETFM LPVDWKDGWP LILEQAKTVP 360 YAVTKPALPA QPPAPLATSG NFAYVDEFDG PLSSAWIGIR IPRTPLYTVE RGDLVLRSGA 420 PLGDLRGVPG FVGRRQQHHV ATASTVVDFV PQRDGDRAGL VAMQNDDNHV FLGVTRSGGK 480 NVVALYKTEG GKETL |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
cd08989 | GH43_XYL | 6.0e-66 | 58 | 346 | 290 | + Glycosyl hydrolase family 43, beta-D-xylosidase. This glycosyl hydrolase family 43 (GH43) includes mostly enzymes that have been characterized to have beta-1,4-xylosidase (beta-D-xylosidase;xylan 1,4-beta-xylosidase; EC 3.2.1.37) activity. They are part of an array of hemicellulases that are involved in the final breakdown of plant cell-wall whereby they degrade xylan. They hydrolyze beta-1,4 glycosidic bonds between two xylose units in short xylooligosaccharides. These are inverting enzymes (i.e. they invert the stereochemistry of the anomeric carbon atom of the substrate) that have an aspartate as the catalytic general base, a glutamate as the catalytic general acid and another aspartate that is responsible for pKa modulation and orienting the catalytic acid. A common structural feature of GH43 enzymes is a 5-bladed beta-propeller domain that contains the catalytic acid and catalytic base. A long V-shaped groove, partially enclosed at one end, forms a single extended substrate-binding surface across the face of the propeller. | ||
cd09001 | GH43_XYL_2 | 3.0e-68 | 56 | 352 | 303 | + Glycosyl hydrolase family 43, beta-D-xylosidase. This glycosyl hydrolase family 43 (GH43) includes mostly enzymes that have been characterized to have beta-1,4-xylosidase (beta-D-xylosidase;xylan 1,4-beta-xylosidase; EC 3.2.1.37) activity. They are part of an array of hemicellulases that are involved in the final breakdown of plant cell-wall whereby they degrade xylan. They hydrolyze beta-1,4 glycosidic bonds between two xylose units in short xylooligosaccharides. These are inverting enzymes (i.e. they invert the stereochemistry of the anomeric carbon atom of the substrate) that have an aspartate as the catalytic general base, a glutamate as the catalytic general acid and another aspartate that is responsible for pKa modulation and orienting the catalytic acid. A common structural feature of GH43 enzymes is a 5-bladed beta-propeller domain that contains the catalytic acid and catalytic base. A long V-shaped groove, partially enclosed at one end, forms a single extended substrate-binding surface across the face of the propeller. | ||
pfam04616 | Glyco_hydro_43 | 2.0e-96 | 56 | 350 | 299 | + Glycosyl hydrolases family 43. The glycosyl hydrolase family 43 contains members that are arabinanase. Rabinanases hydrolyses the alpha-1,5-linked L-arabinofuranoside backbone of plant cell wall arabinans. The structure of arabinanase Arb43A from Cellvibrio japonicus reveals a five-bladed beta-propeller fold. A long V-shaped groove, partially enclosed at one end, forms a single extended substrate-binding surface across the face of the propeller. | ||
COG3507 | XynB | 5.0e-105 | 53 | 483 | 445 | + Beta-xylosidase [Carbohydrate transport and metabolism] | ||
cd09000 | GH43_XYL_1 | 4.0e-161 | 58 | 352 | 298 | + Glycosyl hydrolase family 43, beta-D-xylosidase. This glycosyl hydrolase family 43 (GH43) includes mostly enzymes that have been characterized to have beta-1,4-xylosidase (beta-D-xylosidase;xylan 1,4-beta-xylosidase; EC 3.2.1.37) activity. They are part of an array of hemicellulases that are involved in the final breakdown of plant cell-wall whereby they degrade xylan. They hydrolyze beta-1,4 glycosidic bonds between two xylose units in short xylooligosaccharides. These are inverting enzymes (i.e. they invert the stereochemistry of the anomeric carbon atom of the substrate) that have an aspartate as the catalytic general base, a glutamate as the catalytic general acid and another aspartate that is responsible for pKa modulation and orienting the catalytic acid. A common structural feature of GH43 enzymes is a 5-bladed beta-propeller domain that contains the catalytic acid and catalytic base. A long V-shaped groove, partially enclosed at one end, forms a single extended substrate-binding surface across the face of the propeller. |
Gene Ontology | |
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GO Term | Description |
GO:0004553 | hydrolase activity, hydrolyzing O-glycosyl compounds |
GO:0005975 | carbohydrate metabolic process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | XP_002536919.1 | 0 | 1 | 495 | 1 | 495 | beta-xylosidase, putative [Ricinus communis] |
RefSeq | YP_002131318.1 | 0 | 34 | 493 | 20 | 473 | xylosidase/arabinosidase [Phenylobacterium zucineum HLK1] |
RefSeq | YP_003061161.1 | 0 | 1 | 495 | 1 | 499 | Xylan 1,4-beta-xylosidase [Hirschia baltica ATCC 49814] |
RefSeq | ZP_01301602.1 | 0 | 7 | 495 | 4 | 483 | xylosidase/arabinosidase [Sphingomonas sp. SKA58] |
RefSeq | ZP_04768707.1 | 0 | 16 | 489 | 6 | 481 | glycoside hydrolase family 43 [Asticcacaulis excentricus CB 48] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 1yrz_B | 0 | 58 | 491 | 7 | 434 | A Chain A, Crystal Structure Of Xylan Beta-1,4-Xylosidase From Bacillus Halodurans C-125 |
PDB | 1yrz_A | 0 | 58 | 491 | 7 | 434 | A Chain A, Crystal Structure Of Xylan Beta-1,4-Xylosidase From Bacillus Halodurans C-125 |
PDB | 2exh_D | 0 | 58 | 475 | 6 | 424 | A Chain A, Structure Of The Family43 Beta-Xylosidase From Geobacillus Stearothermophilus |
PDB | 2exh_C | 0 | 58 | 475 | 6 | 424 | A Chain A, Structure Of The Family43 Beta-Xylosidase From Geobacillus Stearothermophilus |
PDB | 2exh_B | 0 | 58 | 475 | 6 | 424 | A Chain A, Structure Of The Family43 Beta-Xylosidase From Geobacillus Stearothermophilus |
Signal Peptide | |||||
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Cleavage Site | |||||
24 |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
DY271994 | 303 | 56 | 349 | 0 |
FC903633 | 279 | 48 | 323 | 0 |
GT035053 | 247 | 52 | 291 | 5e-34 |
GT035053 | 48 | 305 | 350 | 5e-34 |
HO446877 | 461 | 42 | 478 | 2e-28 |
Orthologous Group | |||||
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Species | ID | ||||
Ricinus communis | 35285.m000016 | 32604.m000021 |
Sequence Alignments (This image is cropped. Click for full image.) |
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