| Basic Information | |
|---|---|
| Species | Medicago truncatula |
| Cazyme ID | AC235662_6.1 |
| Family | AA7 |
| Protein Properties | Length: 546 Molecular Weight: 61968.2 Isoelectric Point: 7.8929 |
| Chromosome | Chromosome/Scaffold: 2356628 Start: 18825 End: 20462 |
| Description | FAD-binding Berberine family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| AA7 | 68 | 309 | 0 |
| QNLRFASNTTPKPLFIITPKQISQIQTTIICSQIHNLQIRIRSGGHDFEGRSYVSEVPFIILDLTNFREIEVDVENRTAWVQSGATIGELYYTIYRKNQN LGFPGGECPTIGVGGHISGGGYGTLVRKFGLAADNIIDAHIIDVKGRFLDREAMGEDLFWAIRGGGGASFGVIISWKIKLVQVPSIVTVFNVPKTLEHNA TKLIHKWQFLTSRIDENLEITVILQRVNSSIKGKSKSTVQAI | |||
| Full Sequence |
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| Protein Sequence Length: 546 Download |
| MMPLNSYFTI LLIALLFSYT SSSIDTSTHE ENFLECLYSY SHNSTSISEV VYTKTNSSYS 60 SILKFTTQNL RFASNTTPKP LFIITPKQIS QIQTTIICSQ IHNLQIRIRS GGHDFEGRSY 120 VSEVPFIILD LTNFREIEVD VENRTAWVQS GATIGELYYT IYRKNQNLGF PGGECPTIGV 180 GGHISGGGYG TLVRKFGLAA DNIIDAHIID VKGRFLDREA MGEDLFWAIR GGGGASFGVI 240 ISWKIKLVQV PSIVTVFNVP KTLEHNATKL IHKWQFLTSR IDENLEITVI LQRVNSSIKG 300 KSKSTVQAIF QALFLGGVDK LIHLMQEKFP ELGLVREDCV EMSWVESVLY LYGFPKDEPL 360 ETLLNRTLAA KDIYKVKSDF VKIPIPEVGL EGIWPMFHED GAKDAMVICF PYGGIMDNIS 420 ESEIPFPHRH GNLYQIYYSV HWHQESDEVE KMKMNWIGKL YSYMEPFVSK SPRAAYINYR 480 DLDIGVNNIN GYTSYKQASV WGVKYFKNNF KRLIKVKTKV DPLNFFRNEQ SIPSLMCSRD 540 IKKSL* |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| COG0277 | GlcD | 2.0e-10 | 102 | 274 | 181 | + FAD/FMN-containing dehydrogenases [Energy production and conversion] | ||
| pfam01565 | FAD_binding_4 | 5.0e-12 | 102 | 198 | 98 | + FAD binding domain. This family consists of various enzymes that use FAD as a co-factor, most of the enzymes are similar to oxygen oxidoreductase. One of the enzymes Vanillyl-alcohol oxidase (VAO) has a solved structure, the alignment includes the FAD binding site, called the PP-loop, between residues 99-110. The FAD molecule is covalently bound in the known structure, however the residue that links to the FAD is not in the alignment. VAO catalyzes the oxidation of a wide variety of substrates, ranging form aromatic amines to 4-alkylphenols. Other members of this family include D-lactate dehydrogenase, this enzyme catalyzes the conversion of D-lactate to pyruvate using FAD as a co-factor; mitomycin radical oxidase, this enzyme oxidises the reduced form of mitomycins and is involved in mitomycin resistance. This family includes MurB an UDP-N-acetylenolpyruvoylglucosamine reductase enzyme EC:1.1.1.158. This enzyme is involved in the biosynthesis of peptidoglycan. | ||
| pfam08031 | BBE | 3.0e-18 | 475 | 533 | 59 | + Berberine and berberine like. This domain is found in the berberine bridge and berberine bridge- like enzymes which are involved in the biosynthesis of numerous isoquinoline alkaloids. They catalyze the transformation of the N-methyl group of (S)-reticuline into the C-8 berberine bridge carbon of (S)-scoulerine. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0008762 | UDP-N-acetylmuramate dehydrogenase activity |
| GO:0016491 | oxidoreductase activity |
| GO:0050660 | flavin adenine dinucleotide binding |
| GO:0055114 | oxidation-reduction process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| DDBJ | BAB33033.1 | 0 | 1 | 535 | 1 | 532 | CPRD2 [Vigna unguiculata] |
| RefSeq | XP_002299045.1 | 0 | 1 | 535 | 1 | 530 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002332196.1 | 0 | 26 | 535 | 16 | 524 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002333020.1 | 0 | 1 | 535 | 1 | 530 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002333339.1 | 0 | 1 | 535 | 1 | 530 | predicted protein [Populus trichocarpa] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3vte_A | 0 | 30 | 535 | 4 | 513 | A Chain A, Crystal Structure Of Tetrahydrocannabinolic Acid Synthase From Cannabis Sativa |
| PDB | 4dns_B | 0 | 30 | 536 | 10 | 497 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
| PDB | 4dns_A | 0 | 30 | 536 | 10 | 497 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
| PDB | 3tsj_B | 0 | 30 | 536 | 8 | 497 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
| PDB | 3tsj_A | 0 | 30 | 536 | 8 | 497 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
