| Basic Information | |
|---|---|
| Species | Arabidopsis thaliana |
| Cazyme ID | AT1G17270.1 |
| Family | GT68 |
| Protein Properties | Length: 565 Molecular Weight: 63621.8 Isoelectric Point: 7.629 |
| Chromosome | Chromosome/Scaffold: 1 Start: 5909249 End: 5911693 |
| Description | GDP-fucose protein-O-fucosyltransferase 2, putative, expressed |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
 | |||
| Family | Start | End | Evalue |
| GT68 | 244 | 540 | 0 |
| DRVLVIPSSKFDYQYDKVIDIERINTCLGRTVVISFDQFKEIDKKNNAHIDRFICYVSSPQPCYVDEDHIKKLKGLGVSIGGKLEAPWSEDIKKPTKRTS QEVVEKFKSDDGVIAIGDVFYADMEQDLVMQPGGPINHKCKTLIEPSRLILVTAQRFIQTFLGKNFISLHLRRHGFLKFCNAKSPSCFYPIPQAADCISR MVERANAPVIYLSTDAAESETGLLQSLVVVDGKVVPLVKRPPQNSAEKWDSLLYRHGIEDDSQVYAMLDKTICAMSSVFIGASGSTFTEDILRLRKD | |||
| Full Sequence |
|---|
| Protein Sequence Length: 565 Download |
| MVRNSSDEEE DHRNLIPQND TRDNDLNLRP DARTVNMANG GGRSPRSALQ IDEILSRARN 60 RWKISVNKRY VVAAVSLTLF VGLLFLFTDT RTFFSSFKLD PMSSRVKESE LQALNLLRQQ 120 QLALVSLLNR TNFNSSNAIS SSVVIDNVKA ALLKQISVNK EIEEVLLSPH RTGNYSITAS 180 GSDSFTGSYN ADICRKVDQK LLDRKTIEWK PRPDKFLFAI CLSGQMSNHL ICLEKHMFFA 240 ALLDRVLVIP SSKFDYQYDK VIDIERINTC LGRTVVISFD QFKEIDKKNN AHIDRFICYV 300 SSPQPCYVDE DHIKKLKGLG VSIGGKLEAP WSEDIKKPTK RTSQEVVEKF KSDDGVIAIG 360 DVFYADMEQD LVMQPGGPIN HKCKTLIEPS RLILVTAQRF IQTFLGKNFI SLHLRRHGFL 420 KFCNAKSPSC FYPIPQAADC ISRMVERANA PVIYLSTDAA ESETGLLQSL VVVDGKVVPL 480 VKRPPQNSAE KWDSLLYRHG IEDDSQVYAM LDKTICAMSS VFIGASGSTF TEDILRLRKD 540 WGTSSMCDEY LCRGEEPNFI AENE* |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
 | ||||||||
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| cd11296 | O-FucT_like | 0.0005 | 216 | 250 | 35 | + GDP-fucose protein O-fucosyltransferase and related proteins. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. | ||
| cd11548 | NodZ_like | 0.0001 | 341 | 539 | 199 | + Alpha 1,6-fucosyltransferase similar to Bradyrhizobium NodZ. Bradyrhizobium NodZ is an alpha 1,6-fucosyltransferase involved in the biosynthesis of the nodulation factor, a lipo-chitooligosaccharide formed by three-to-six beta-1,4-linked N-acetyl-d-glucosamine (GlcNAc) residues and a fatty acid acyl group attached to the nitrogen atom at the non-reducing end. NodZ transfers L-fucose from the GDP-beta-L-fucose donor to the reducing residue of the chitin oligosaccharide backbone, before the attachment of a fatty acid group. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. | ||
| cd11298 | O-FucT-2 | 9.0e-10 | 405 | 531 | 127 | + GDP-fucose protein O-fucosyltransferase 2. O-FucT-2 adds O-fucose to thrombospondin type 1 repeats (TSRs), and appears conserved in bilateria. The O-fucosylation of TSRs appears to play a role in regulating secretion of metalloproteases of the ADAMTS superfamily. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. | ||
| cd11296 | O-FucT_like | 1.0e-17 | 380 | 538 | 169 | + GDP-fucose protein O-fucosyltransferase and related proteins. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003674 | molecular_function |
| GO:0005575 | cellular_component |
| GO:0008150 | biological_process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAD50008.1 | 0 | 1 | 564 | 1 | 594 | AC007651_3 Hypothetical Protein [Arabidopsis thaliana] |
| GenBank | AAM66093.1 | 0 | 1 | 564 | 1 | 566 | unknown [Arabidopsis thaliana] |
| RefSeq | NP_173170.2 | 0 | 1 | 564 | 1 | 564 | unknown protein [Arabidopsis thaliana] |
| RefSeq | NP_199853.1 | 0 | 1 | 564 | 1 | 566 | unknown protein [Arabidopsis thaliana] |
| RefSeq | XP_002264087.1 | 0 | 1 | 564 | 1 | 559 | PREDICTED: hypothetical protein [Vitis vinifera] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 4ap6_D | 0.003 | 405 | 531 | 277 | 383 | A Chain A, Crystal Structure Of Human Pofut2 E54a Mutant In Complex With Gdp- Fucose |
| PDB | 4ap6_C | 0.003 | 405 | 531 | 277 | 383 | A Chain A, Crystal Structure Of Human Pofut2 E54a Mutant In Complex With Gdp- Fucose |
| PDB | 4ap6_B | 0.003 | 405 | 531 | 277 | 383 | A Chain A, Crystal Structure Of Human Pofut2 E54a Mutant In Complex With Gdp- Fucose |
| PDB | 4ap6_A | 0.003 | 405 | 531 | 277 | 383 | A Chain A, Crystal Structure Of Human Pofut2 E54a Mutant In Complex With Gdp- Fucose |
| PDB | 4ap5_B | 0.004 | 405 | 531 | 263 | 369 | A Chain A, Crystal Structure Of Human Pofut2 |
