Basic Information | |
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Species | Brachypodium distachyon |
Cazyme ID | Bradi4g40070.1 |
Family | GT47 |
Protein Properties | Length: 535 Molecular Weight: 59786.4 Isoelectric Point: 5.8367 |
Chromosome | Chromosome/Scaffold: 4 Start: 44578148 End: 44579837 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 84 | 460 | 0 |
CEGRYVYMVDLPSRYDVLRDCVEGSPEFDKWYSQCTLMSNAGMGPALPAPTGDGTDGDTGLIGPDAAGWYNTDQYALEVIFHNRMRRYPCLTGNPSSATA VYVPYYPALELQQHLCGDTNSDARDRPSSEFIQWLSSQPRWTTLGGRDHFLVASKTTWMFRRLVQQGAGGEKKNRYCGNNFLDSHPETANMTVLTYESNL WSTRREDFAVPYPSYFHPSSADAVSAWQARVRSAPRRWLFAFAGARRANGSLPIRDRIIDACAASSRCGRVDCGEGHGDLEGYITCRTPRRLVSIFGASR FCLQPRGDSFMRRSSVDAVMAGCVPVFFHQPSTFKTQYRWHEPDPEKKINGGDERRYSVLIDADEVMQGKVDIEEVL |
Full Sequence |
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Protein Sequence Length: 535 Download |
MEAHYPKYVL YGVLIVGSWL VSSILHFQFF HLSLFSSSRL RGVALLAVDE PPVPAISLNA 60 SFIGLPENPP ATVVAEDNGA AAACEGRYVY MVDLPSRYDV LRDCVEGSPE FDKWYSQCTL 120 MSNAGMGPAL PAPTGDGTDG DTGLIGPDAA GWYNTDQYAL EVIFHNRMRR YPCLTGNPSS 180 ATAVYVPYYP ALELQQHLCG DTNSDARDRP SSEFIQWLSS QPRWTTLGGR DHFLVASKTT 240 WMFRRLVQQG AGGEKKNRYC GNNFLDSHPE TANMTVLTYE SNLWSTRRED FAVPYPSYFH 300 PSSADAVSAW QARVRSAPRR WLFAFAGARR ANGSLPIRDR IIDACAASSR CGRVDCGEGH 360 GDLEGYITCR TPRRLVSIFG ASRFCLQPRG DSFMRRSSVD AVMAGCVPVF FHQPSTFKTQ 420 YRWHEPDPEK KINGGDERRY SVLIDADEVM QGKVDIEEVL GRYTDQEVAA MREEVIKMIP 480 RFLYKDPRVR FDGETRDAFD IAIDEVLERV RRIKNGEDLG LEDADGQLVV AKDL* 540 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 4.0e-58 | 83 | 460 | 385 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ABA96790.1 | 0 | 1 | 533 | 1 | 526 | Exostosin family protein, expressed [Oryza sativa (japonica cultivar-group)] |
DDBJ | BAH95576.1 | 0 | 153 | 533 | 94 | 465 | Os12g0224400 [Oryza sativa Japonica Group] |
GenBank | EEC69035.1 | 0 | 100 | 533 | 1 | 390 | hypothetical protein OsI_37846 [Oryza sativa Indica Group] |
GenBank | EEE52961.1 | 0 | 100 | 533 | 1 | 423 | hypothetical protein OsJ_35605 [Oryza sativa Japonica Group] |
RefSeq | XP_002443053.1 | 0 | 1 | 519 | 1 | 510 | hypothetical protein SORBIDRAFT_08g007160 [Sorghum bicolor] |