| Basic Information | |
|---|---|
| Species | Chlamydomonas reinhardtii |
| Cazyme ID | Cre16.g690150.t1.2 |
| Family | GT57 |
| Protein Properties | Length: 604 Molecular Weight: 63474.9 Isoelectric Point: 9.6176 |
| Chromosome | Chromosome/Scaffold: 16 Start: 3878354 End: 3882819 |
| Description | ALG6, ALG8 glycosyltransferase family |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT57 | 24 | 157 | 0 |
| VLIRVLTGLSGYSGAGDPPKYGDYEAQRHWMELTVNLPVREWYVDSPVNNASYWPLDYPPLSGYQSWLCGVALRAAEPAAVALVSSHGYESASSKTLMRW TVIVADLLIYIPACLVAVAVFYPSPDTSAAAATA | |||
| GT57 | 206 | 572 | 0 |
| SAAARRGRLLALFGLLFNPALLLIDHGHFQYNGISLGLTLAAVAAIARGRRLLGGVLYVAALNHKHMALFFAPAFFAHLLGWALHDPAHRGVPAKLLAVA KLGATVLLAFAVCWAPWLHSRQALLQVLSRIFPVRRGLYEDYVANWWCASSAALKWKSRFPPHLLLRAAAATTLAAAAPAMAHQIAGGGGGGGGGGGPSR WGLVRCLVNSGFAFYMFSYQVHEKSILMPLLPLTLAAGREPTLAAWLPLLACFSMFPLLVRDGVGLPYVAAAAVYGAVMAGAALQQARQLQAERRAAPRP GALARVVDAVTGLMVDLWPLLAAAGVAAAAALHGARLLLPAPPHLPWLYDRAFITFSFCGFAAAFCY | |||
| Full Sequence |
|---|
| Protein Sequence Length: 604 Download |
| MMSSILEFLG DDSKSTGLLV LLAVLIRVLT GLSGYSGAGD PPKYGDYEAQ RHWMELTVNL 60 PVREWYVDSP VNNASYWPLD YPPLSGYQSW LCGVALRAAE PAAVALVSSH GYESASSKTL 120 MRWTVIVADL LIYIPACLVA VAVFYPSPDT SAAAATAGSA SSPAASPTKT PSSTGTAAAS 180 TCASPAGALP PPFSHSPSFS SATALSAAAR RGRLLALFGL LFNPALLLID HGHFQYNGIS 240 LGLTLAAVAA IARGRRLLGG VLYVAALNHK HMALFFAPAF FAHLLGWALH DPAHRGVPAK 300 LLAVAKLGAT VLLAFAVCWA PWLHSRQALL QVLSRIFPVR RGLYEDYVAN WWCASSAALK 360 WKSRFPPHLL LRAAAATTLA AAAPAMAHQI AGGGGGGGGG GGPSRWGLVR CLVNSGFAFY 420 MFSYQVHEKS ILMPLLPLTL AAGREPTLAA WLPLLACFSM FPLLVRDGVG LPYVAAAAVY 480 GAVMAGAALQ QARQLQAERR AAPRPGALAR VVDAVTGLMV DLWPLLAAAG VAAAAALHGA 540 RLLLPAPPHL PWLYDRAFIT FSFCGFAAAF CYSQLAQWLE EPVGSGPVAV AAKQRAARRL 600 KDE* 660 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03155 | Alg6_Alg8 | 9.0e-28 | 31 | 136 | 107 | + ALG6, ALG8 glycosyltransferase family. N-linked (asparagine-linked) glycosylation of proteins is mediated by a highly conserved pathway in eukaryotes, in which a lipid (dolichol phosphate)-linked oligosaccharide is assembled at the endoplasmic reticulum membrane prior to the transfer of the oligosaccharide moiety to the target asparagine residues. This oligosaccharide is composed of Glc(3)Man(9)GlcNAc(2). The addition of the three glucose residues is the final series of steps in the synthesis of the oligosaccharide precursor. Alg6 transfers the first glucose residue, and Alg8 transfers the second one. In the human alg6 gene, a C->T transition, which causes Ala333 to be replaced with Val, has been identified as the cause of a congenital disorder of glycosylation, designated as type Ic OMIM:603147. | ||
| pfam03155 | Alg6_Alg8 | 5.0e-52 | 229 | 467 | 242 | + ALG6, ALG8 glycosyltransferase family. N-linked (asparagine-linked) glycosylation of proteins is mediated by a highly conserved pathway in eukaryotes, in which a lipid (dolichol phosphate)-linked oligosaccharide is assembled at the endoplasmic reticulum membrane prior to the transfer of the oligosaccharide moiety to the target asparagine residues. This oligosaccharide is composed of Glc(3)Man(9)GlcNAc(2). The addition of the three glucose residues is the final series of steps in the synthesis of the oligosaccharide precursor. Alg6 transfers the first glucose residue, and Alg8 transfers the second one. In the human alg6 gene, a C->T transition, which causes Ala333 to be replaced with Val, has been identified as the cause of a congenital disorder of glycosylation, designated as type Ic OMIM:603147. | ||
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | EEY69318.1 | 0 | 6 | 581 | 14 | 519 | dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase, putative [Phytophthora infestans T30-4] |
| RefSeq | NP_001058960.1 | 0 | 15 | 480 | 137 | 523 | Os07g0164500 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | XP_001699186.1 | 0 | 1 | 582 | 1 | 582 | glycosyl transferase, type ALG6, ALG8 [Chlamydomonas reinhardtii] |
| RefSeq | XP_002198815.1 | 0 | 17 | 498 | 8 | 419 | PREDICTED: dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase [Taeniopygia guttata] |
| RefSeq | XP_972276.1 | 0 | 21 | 468 | 18 | 396 | PREDICTED: similar to predicted protein [Tribolium castaneum] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| dolichyl-diphosphooligosaccharide biosynthesis | RXN-5470 | EC-2.4.1.267 | Dol-P-Glc:Man9GlcNAc2-PP-Dol α-1,3-glucosyltransferase |
