y
Basic Information | |
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Species | Zea mays |
Cazyme ID | GRMZM2G048010_T01 |
Family | GT47 |
Protein Properties | Length: 475 Molecular Weight: 53775.3 Isoelectric Point: 10.1375 |
Chromosome | Chromosome/Scaffold: 3 Start: 215380332 End: 215382314 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 135 | 422 | 0 |
RILKVYIYQDGRRPIFHTPPLSGIYASEGWFMKLLKESRRHVVADAGKAHLFYLPYSSQQLRLTLYEAGSHNLRPLAAYLRNFVRGLASKYPFWNRTRGA DHFLVACHDWGPYTTTAHRDLRKNAIKALCNADSSEGIFTPGKDVSLPETTIRTPRRPLRYVGGLPVSRRSILAFFAGNVHGRVRPVLLRHWGNGQDDDM RVYSLLPSRVSRRMNYIQHMKNSRFCLCPMGYEVNSPRIVEALYYECVPVIIADNFVLPFSEVLDWSAFSVVIAEKDIPDLKKILKGI |
Full Sequence |
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Protein Sequence Length: 475 Download |
MMSVSCCHLA ALVSILAAGA ATALLTLSLP SSPGASTTRR TDFAGALSVA NETPPLPHLS 60 APPAPATPPP APPSPPADRP RKREPSFWRM APEEALRYAK KEIRDAEPVL DDPDLYAPLF 120 KNVSQFKRSY ELMERILKVY IYQDGRRPIF HTPPLSGIYA SEGWFMKLLK ESRRHVVADA 180 GKAHLFYLPY SSQQLRLTLY EAGSHNLRPL AAYLRNFVRG LASKYPFWNR TRGADHFLVA 240 CHDWGPYTTT AHRDLRKNAI KALCNADSSE GIFTPGKDVS LPETTIRTPR RPLRYVGGLP 300 VSRRSILAFF AGNVHGRVRP VLLRHWGNGQ DDDMRVYSLL PSRVSRRMNY IQHMKNSRFC 360 LCPMGYEVNS PRIVEALYYE CVPVIIADNF VLPFSEVLDW SAFSVVIAEK DIPDLKKILK 420 GISLRRYVAM HDSVKRLQRH FLWHARPIKY DLFHMILHSI WLSRVNQVQV QLEG* 480 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 1.0e-73 | 137 | 422 | 302 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | EEC71161.1 | 0 | 1 | 471 | 29 | 498 | hypothetical protein OsI_03019 [Oryza sativa Indica Group] |
GenBank | EEE55063.1 | 0 | 1 | 471 | 29 | 481 | hypothetical protein OsJ_02778 [Oryza sativa Japonica Group] |
RefSeq | NP_001043679.1 | 0 | 1 | 471 | 29 | 500 | Os01g0640600 [Oryza sativa (japonica cultivar-group)] |
RefSeq | XP_002269459.1 | 0 | 87 | 472 | 153 | 537 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002456034.1 | 0 | 2 | 471 | 36 | 516 | hypothetical protein SORBIDRAFT_03g029210 [Sorghum bicolor] |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |