| Basic Information | |
|---|---|
| Species | Zea mays |
| Cazyme ID | GRMZM2G059825_T01 |
| Family | GT47 |
| Protein Properties | Length: 416 Molecular Weight: 46474.5 Isoelectric Point: 6.6687 |
| Chromosome | Chromosome/Scaffold: 6 Start: 162556092 End: 162559012 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
 | |||
| Family | Start | End | Evalue |
| GT47 | 48 | 343 | 0 |
| RLKVYVYDLPSKYNKKLLKKDPRCLNHMFAAEIFMHRFLLSSAVRTFNPEEADWFYTPVYTTCDLTPKGLPLPFKSPRMMRSAIQLIATNWPYWNRSEGA DHFFVTPHDFGACFHYQEEKAIGRGILPLLQRATLVQTFGQKNHVCLKDGSITIPPYAPPQKMQTHLIPPDTPRSIFVYFRGLFYDTGNDPEGGYYARGA RASVWENFKNNPLFDISTDHPPTYYEDMQRSVFCLCPLGWAPWSPRLVEAVVFGCIPVIIADDIVLPFADAIPWEEIGVFVAEDDVPQLDSILTSI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 416 Download |
| MGKGSARALA LALAVILACS DVAVVTAQET ERIEGSAGDV LEDDPVGRLK VYVYDLPSKY 60 NKKLLKKDPR CLNHMFAAEI FMHRFLLSSA VRTFNPEEAD WFYTPVYTTC DLTPKGLPLP 120 FKSPRMMRSA IQLIATNWPY WNRSEGADHF FVTPHDFGAC FHYQEEKAIG RGILPLLQRA 180 TLVQTFGQKN HVCLKDGSIT IPPYAPPQKM QTHLIPPDTP RSIFVYFRGL FYDTGNDPEG 240 GYYARGARAS VWENFKNNPL FDISTDHPPT YYEDMQRSVF CLCPLGWAPW SPRLVEAVVF 300 GCIPVIIADD IVLPFADAIP WEEIGVFVAE DDVPQLDSIL TSIPTDVVLR KQRLLANPSM 360 KQAMLFPQPA QPGDAFHQIL NGLARKLPHG SNVFLKPGER ALNWTAGPPG DLKPW* 420 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 7.0e-89 | 48 | 343 | 304 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | NP_001045264.1 | 0 | 24 | 415 | 26 | 417 | Os01g0926700 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | NP_001130448.1 | 0 | 1 | 415 | 1 | 415 | hypothetical protein LOC100191546 [Zea mays] |
| RefSeq | NP_001150738.1 | 0 | 1 | 415 | 1 | 415 | secondary cell wall-related glycosyltransferase family 47 [Zea mays] |
| RefSeq | XP_002440184.1 | 0 | 1 | 415 | 1 | 415 | hypothetical protein SORBIDRAFT_09g027440 [Sorghum bicolor] |
| RefSeq | XP_002459017.1 | 0 | 27 | 415 | 32 | 420 | hypothetical protein SORBIDRAFT_03g044530 [Sorghum bicolor] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
