| Basic Information | |
|---|---|
| Species | Vitis vinifera |
| Cazyme ID | GSVIVT01021720001 |
| Family | AA7 |
| Protein Properties | Length: 824 Molecular Weight: 92372.3 Isoelectric Point: 8.5235 |
| Chromosome | Chromosome/Scaffold: 10 Start: 10002316 End: 10010600 |
| Description | FAD-binding Berberine family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| AA7 | 63 | 170 | 6e-34 |
| YGSMMRKYGLGADNVMDARIVDVHGRILDRESMGEDLFWAIRGGGGASFGIILWWKIRLVPVPSTVTVFTVGRALEQGATKLLYRWQQVADKLHEDLFIR VIISVKAN | |||
| AA7 | 517 | 648 | 0 |
| YYQIATRSSTLGFPAGVCPTVGVGGHFSGGGQGTMTRKYGLASDNVLDAIMVDANGTILDRESMSEDLFWAIRGGGGASFGVILSWKIKLVPVPPIVTIC NVPKTLEQGATKLAHLWQQIAPKLHEDINMRS | |||
| Full Sequence |
|---|
| Protein Sequence Length: 824 Download |
| MVYSNFAMFP LLFILLSASV TASDPILEKF SQCVSLNSEI LIPVSTAFYT PNTTSFRPFL 60 CAYGSMMRKY GLGADNVMDA RIVDVHGRIL DRESMGEDLF WAIRGGGGAS FGIILWWKIR 120 LVPVPSTVTV FTVGRALEQG ATKLLYRWQQ VADKLHEDLF IRVIISVKAN EKGNKTVSAA 180 FNSLFLGGVD RLLQIMGESF PELGLTMKDC TEMSWIRSVL YIGGYPSGTP PEVLLQGKST 240 FKNYFKAKSD FVKEPIPENA LEGLWTRLLE EESPLMIWNP YGGMMSKISE SEIPFPHRKG 300 NIFKIQLYCY MTPYVSMFPR AAYVNYRDLD LGINKNSNTS FIQASVWGAK YFKGNFNRLV 360 HVKTKVDPDN FFRHEQSIPP MPQLIKGSVH GLEYCSTMES LLFFLLLSLL FHVSCAFQSP 420 RSNFLPCMVS HSLPSSQINQ VVYSPDSLSY SSILHSSIQN LRFMNSSSPQ FIITPQSETH 480 VQAAVICSRN LGLGVRVRSG GHDYEGLSYK AACPFLYYQI ATRSSTLGFP AGVCPTVGVG 540 GHFSGGGQGT MTRKYGLASD NVLDAIMVDA NGTILDRESM SEDLFWAIRG GGGASFGVIL 600 SWKIKLVPVP PIVTICNVPK TLEQGATKLA HLWQQIAPKL HEDINMRSIK VLMNRSHEIK 660 GYFKGKSDYV NQPIPESELE GMLKVFLEGE AGVMMWDPYG GKMSEIAEDE TPFPHRAGIL 720 YNIQYFNKWE EAGVEAQRKH MEWTNNIYNY MTPFVSKSPR RAFLNYKDID LGRNDENGNT 780 SFSQAGFWGQ SYFKNNFKRL ALVKGRVDPS NFFRDEQSIP PLR* 840 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| COG0277 | GlcD | 6.0e-9 | 469 | 633 | 201 | + FAD/FMN-containing dehydrogenases [Energy production and conversion] | ||
| pfam01565 | FAD_binding_4 | 9.0e-11 | 469 | 576 | 137 | + FAD binding domain. This family consists of various enzymes that use FAD as a co-factor, most of the enzymes are similar to oxygen oxidoreductase. One of the enzymes Vanillyl-alcohol oxidase (VAO) has a solved structure, the alignment includes the FAD binding site, called the PP-loop, between residues 99-110. The FAD molecule is covalently bound in the known structure, however the residue that links to the FAD is not in the alignment. VAO catalyzes the oxidation of a wide variety of substrates, ranging form aromatic amines to 4-alkylphenols. Other members of this family include D-lactate dehydrogenase, this enzyme catalyzes the conversion of D-lactate to pyruvate using FAD as a co-factor; mitomycin radical oxidase, this enzyme oxidises the reduced form of mitomycins and is involved in mitomycin resistance. This family includes MurB an UDP-N-acetylenolpyruvoylglucosamine reductase enzyme EC:1.1.1.158. This enzyme is involved in the biosynthesis of peptidoglycan. | ||
| pfam08031 | BBE | 1.0e-14 | 762 | 820 | 59 | + Berberine and berberine like. This domain is found in the berberine bridge and berberine bridge- like enzymes which are involved in the biosynthesis of numerous isoquinoline alkaloids. They catalyze the transformation of the N-methyl group of (S)-reticuline into the C-8 berberine bridge carbon of (S)-scoulerine. | ||
| pfam08031 | BBE | 3.0e-19 | 322 | 379 | 58 | + Berberine and berberine like. This domain is found in the berberine bridge and berberine bridge- like enzymes which are involved in the biosynthesis of numerous isoquinoline alkaloids. They catalyze the transformation of the N-methyl group of (S)-reticuline into the C-8 berberine bridge carbon of (S)-scoulerine. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0008762 | UDP-N-acetylmuramate dehydrogenase activity |
| GO:0016491 | oxidoreductase activity |
| GO:0050660 | flavin adenine dinucleotide binding |
| GO:0055114 | oxidation-reduction process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI31062.1 | 0 | 1 | 823 | 1 | 823 | unnamed protein product [Vitis vinifera] |
| RefSeq | XP_002268281.1 | 0 | 65 | 381 | 183 | 516 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002268281.1 | 0 | 412 | 823 | 15 | 517 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002268361.1 | 0 | 62 | 393 | 187 | 539 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002268361.1 | 0 | 404 | 822 | 9 | 527 | PREDICTED: hypothetical protein [Vitis vinifera] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 4dns_B | 0 | 423 | 822 | 12 | 496 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
| PDB | 4dns_B | 0 | 66 | 381 | 169 | 496 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
| PDB | 4dns_A | 0 | 423 | 822 | 12 | 496 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
| PDB | 4dns_A | 0 | 66 | 381 | 169 | 496 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
| PDB | 3vte_A | 0 | 65 | 382 | 165 | 514 | A Chain A, Crystal Structure Of Tetrahydrocannabinolic Acid Synthase From Cannabis Sativa |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| cannabinoid biosynthesis | RXN-7854 | EC-1.21.3 | tetrahydrocannabinolic acid synthase |
