y
Basic Information | |
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Species | Linum usitatissimum |
Cazyme ID | Lus10024214 |
Family | GT47 |
Protein Properties | Length: 443 Molecular Weight: 50296.6 Isoelectric Point: 9.593 |
Chromosome | Chromosome/Scaffold: 165 Start: 310893 End: 313167 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 91 | 375 | 0 |
GRLTCHPNNAVLKHSMEYWLTLDLLASNVPSIVRSCTAIRVDNSSEADIIFVPFFSSLSYNRHSKPLGRQKVVLNKILQDKLVKYLMDQDLWKRYGGKDH LIFAHHPNSMAYSRKKLASAMFVLADFGRYPEKVANIRKDVIAPYKHVVRSIPNAKSAQFDQRPTLAYFKGAIYRKDGGATRQELYYLLKDEKDVDFTFG SYGKDGVKKAAEGMAASKFCFHIAGDTPSSNRLFDIIATHCIPVIISDTIELPFEDELDYSDFSVFVHASDSVKPGYLLKLLRGI |
Full Sequence |
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Protein Sequence Length: 443 Download |
MSEKTRTPSR LLFYLITLSL FLLILSSLSL RQFGNVSLLP GSVFGLILVN ETSIYSNSDF 60 QTSSNNITPF FSPLASITQS SNEGRPCSTS GRLTCHPNNA VLKHSMEYWL TLDLLASNVP 120 SIVRSCTAIR VDNSSEADII FVPFFSSLSY NRHSKPLGRQ KVVLNKILQD KLVKYLMDQD 180 LWKRYGGKDH LIFAHHPNSM AYSRKKLASA MFVLADFGRY PEKVANIRKD VIAPYKHVVR 240 SIPNAKSAQF DQRPTLAYFK GAIYRKDGGA TRQELYYLLK DEKDVDFTFG SYGKDGVKKA 300 AEGMAASKFC FHIAGDTPSS NRLFDIIATH CIPVIISDTI ELPFEDELDY SDFSVFVHAS 360 DSVKPGYLLK LLRGIKRDVW TEMWLKLQEI TFHFEYRYPS QPGDAVDMIW NAVSRKLDSV 420 RLQANRKNRY HRAYQNQIEQ TV* 480 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 1.0e-48 | 104 | 375 | 281 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_565089.1 | 0 | 1 | 433 | 4 | 452 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002284930.1 | 0 | 1 | 433 | 1 | 448 | PREDICTED: hypothetical protein isoform 1 [Vitis vinifera] |
RefSeq | XP_002284932.1 | 0 | 70 | 433 | 45 | 409 | PREDICTED: hypothetical protein isoform 2 [Vitis vinifera] |
RefSeq | XP_002320639.1 | 0 | 80 | 432 | 24 | 374 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002514760.1 | 0 | 1 | 432 | 1 | 486 | catalytic, putative [Ricinus communis] |