| Basic Information | |
|---|---|
| Species | Malus domestica |
| Cazyme ID | MDP0000156362 |
| Family | GH47 |
| Protein Properties | Length: 651 Molecular Weight: 73486.3 Isoelectric Point: 7.951 |
| Chromosome | Chromosome/Scaffold: 000424302 Start: 1441 End: 7542 |
| Description | alpha-mannosidase 1 |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GH47 | 225 | 356 | 0 |
| TPQSKNGVNSFGGLGATLVDSLDTLYIMGLHEQFQKAREWIATSLDFDKDYEASVFETTIRVVGGLLSAYDLSEDKLFLDKAREIADRLLPAWDTPSGIP YNIINLAHGRPHNPSWTGGDSILADSGTEQAE | |||
| GH47 | 354 | 619 | 0 |
| QAEKVIVELNKTFPDDGLLPIYINPERGTSGRXIITFGAMGDSFYEYLLKVWIQGNKTSAVKPYRDMWEKSMTGLLSLIRRTTPSSFAYMCEKNGNXLTN KMDELACFAPGMLALGSSGYGPDDSKKFLTLAEELAWTCYNFYQSTPTKLAGENYFFYAGQDLSVGTSWNILRPETVESLFYLWRLTGNKTYQEWGWNIF QAFEKNSRIESGYVGLKDVNTGEKDNMMQSFFLAETLKYLYLLFSPSSVISLDEWVFNTEAHPIKI | |||
| Full Sequence |
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| Protein Sequence Length: 651 Download |
| MARVRSSSSS SRLRYCNPAY YLKRPKRLAL LLIAFVSVTL VVWDRQTLLR EHEEEVAKLS 60 EQLSHLKSLV EDSQNVQGDA TKKVMLKGRG GEKEVVLDPI DIQRREKVKE AMIHAWSSYE 120 KYAWGQDELQ LAEGVTLSML SSFGPTFSQY LKAEAVLLFI PLKSVRRQRG TFGGMSLFYI 180 LLGRGVHVSI LINSVSVSVL SQESRSIKVV WAQSQFYLYR PQLDTPQSKN GVNSFGGLGA 240 TLVDSLDTLY IMGLHEQFQK AREWIATSLD FDKDYEASVF ETTIRVVGGL LSAYDLSEDK 300 LFLDKAREIA DRLLPAWDTP SGIPYNIINL AHGRPHNPSW TGGDSILADS GTEQAEKVIV 360 ELNKTFPDDG LLPIYINPER GTSGRXIITF GAMGDSFYEY LLKVWIQGNK TSAVKPYRDM 420 WEKSMTGLLS LIRRTTPSSF AYMCEKNGNX LTNKMDELAC FAPGMLALGS SGYGPDDSKK 480 FLTLAEELAW TCYNFYQSTP TKLAGENYFF YAGQDLSVGT SWNILRPETV ESLFYLWRLT 540 GNKTYQEWGW NIFQAFEKNS RIESGYVGLK DVNTGEKDNM MQSFFLAETL KYLYLLFSPS 600 SVISLDEWVF NTEAHPIKIV ARHDAVTSGI ANGNDRPKIR LRGRKAGRTR E 660 |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam01532 | Glyco_hydro_47 | 0.0002 | 111 | 146 | 36 | + Glycosyl hydrolase family 47. Members of this family are alpha-mannosidases that catalyze the hydrolysis of the terminal 1,2-linked alpha-D-mannose residues in the oligo-mannose oligosaccharide Man(9)(GlcNAc)(2). | ||
| PTZ00470 | PTZ00470 | 3.0e-8 | 101 | 129 | 29 | + glycoside hydrolase family 47 protein; Provisional | ||
| PTZ00470 | PTZ00470 | 4.0e-167 | 230 | 619 | 419 | + glycoside hydrolase family 47 protein; Provisional | ||
| pfam01532 | Glyco_hydro_47 | 9.0e-179 | 226 | 619 | 431 | + Glycosyl hydrolase family 47. Members of this family are alpha-mannosidases that catalyze the hydrolysis of the terminal 1,2-linked alpha-D-mannose residues in the oligo-mannose oligosaccharide Man(9)(GlcNAc)(2). | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity |
| GO:0005509 | calcium ion binding |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAF16414.1 | 3e-29 | 12 | 147 | 14 | 151 | AF126550_1 mannosyl-oligosaccharide 1,2-alpha-mannosidase [Glycine max] |
| GenBank | AAF16414.1 | 0 | 182 | 649 | 88 | 577 | AF126550_1 mannosyl-oligosaccharide 1,2-alpha-mannosidase [Glycine max] |
| EMBL | CBI18472.1 | 3e-32 | 1 | 147 | 1 | 146 | unnamed protein product [Vitis vinifera] |
| EMBL | CBI18472.1 | 0 | 210 | 648 | 114 | 571 | unnamed protein product [Vitis vinifera] |
| RefSeq | XP_002528166.1 | 0 | 210 | 648 | 66 | 521 | mannosyl-oligosaccharide alpha-1,2-mannosidase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 1nxc_A | 0 | 226 | 620 | 47 | 466 | A Chain A, Structure Of Mouse Golgi Alpha-1,2-Mannosidase Ia Reveals The Molecular Basis For Substrate Specificity Among Class I Enzymes (Family 47 Glycosidases) |
| PDB | 1nxc_A | 0.003 | 103 | 130 | 19 | 46 | A Chain A, Structure Of Mouse Golgi Alpha-1,2-Mannosidase Ia Reveals The Molecular Basis For Substrate Specificity Among Class I Enzymes (Family 47 Glycosidases) |
| PDB | 1fmi_A | 0 | 237 | 619 | 47 | 456 | A Chain A, Crystal Structure Of Human Class I Alpha1,2-Mannosidase |
| PDB | 1fo3_A | 0 | 237 | 619 | 47 | 456 | A Chain A, Crystal Structure Of Human Class I Alpha1,2-Mannosidase |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| CU615093 | 321 | 346 | 648 | 0 |
| BX835997 | 294 | 355 | 648 | 0 |
| DY974119 | 306 | 268 | 555 | 0 |
| HO780776 | 420 | 210 | 586 | 0 |
| HO780776 | 130 | 20 | 147 | 2e-34 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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