Basic Information | |
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Species | Malus domestica |
Cazyme ID | MDP0000183693 |
Family | CBM57 |
Protein Properties | Length: 986 Molecular Weight: 107874 Isoelectric Point: 4.8997 |
Chromosome | Chromosome/Scaffold: 007092798 Start: 1909 End: 10031 |
Description | Leucine-rich repeat transmembrane protein kinase |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
CBM57 | 203 | 372 | 1.6e-27 |
SIKCGGKQMTGSDGILYEAEDSALGXATFXVTSTEKWAVSNAGLFSDRKXPSFLXNTLAQVTGTDVTPELFQTSRVSPGSLRYYGLGLXNGPYTVTLHFA ETVYENRTSQKWESLGRRVFDIYIQGTRRTKDFDISKEAGGAKLGIMKRFNVSVSENYLEIHLFWAGKGT | |||
CBM57 | 772 | 939 | 1.7e-32 |
SINCGGTQMIGSDGILYEGDDSELGLATFSVTSIENWAVSNAGSFTDDTPSLNKTHAQVTGTDVTPELFQTSRVSTGSLRYYGLGLENGLYTVTLHFAET VYKSRTSQTWQSLGRRVFDIYIQGTRKMKDFDISKEAGGVNRAVVRKFNVSVSENYLEIHLFWAGKGT |
Full Sequence |
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Protein Sequence Length: 986 Download |
MGINQLPYDF HSFMDSCELG GEIPSTFAKL TNMRAFWASD SPFSGKIPDF IGSWTNLTYL 60 QFQGNSFEGP IPTSFSQLTS LYYLYISDIH NGSSSLDFIK NLKSLXXLKL RNALITGTIP 120 SDIGEYQSLQ TXFLGNNSLS GPLPSQKSNQ LXTIDLSYNF LSGSFPQWVT TISQLNLVVN 180 NFTFDSSNIT FWYYMKLTDG DFSIKCGGKQ MTGSDGILYE AEDSALGXAT FXVTSTEKWA 240 VSNAGLFSDR KXPSFLXNTL AQVTGTDVTP ELFQTSRVSP GSLRYYGLGL XNGPYTVTLH 300 FAETVYENRT SQKWESLGRR VFDIYIQGTR RTKDFDISKE AGGAKLGIMK RFNVSVSENY 360 LEIHLFWAGK GTCCIPEQGD YGPLIAAVHA ASDFTPTVAG LPTTDPSEVR ALNSIFEQWD 420 TQAMSGQWNI SGEPCSGSAI NGTDFESPND IPDINPAIEC DCTYNNGTTC HITKLRIDYN 480 YFTGPLPAFI GNMSAMTVLY IRFNSFSGPI PKELGNLKEL TVLSIGSNNF SGPIPPELGN 540 LVKLERLYMD SCGLSGEIPS TFAKLANMQV LWASDNPFSG KIPDFIGNWT NLTDLQFQGN 600 SFEGPIPTSF SQLTSLLSLR ISDIYDGSSS LDFIKNLKNL IDLKLRNALI TGTIPSGIGE 660 YQSLQTLDLS FNTLAGQLPS SLFNLSSLTS LFLGNNSLSG PLPSQXSXQL XTIDLSNNFL 720 SGSLPQWVTT ISQLNLVFNN FIFNSSNITL PGLNCLQRFP CNRNSPRYAS FSINCGGTQM 780 IGSDGILYEG DDSELGLATF SVTSIENWAV SNAGSFTDDT PSLNKTHAQV TGTDVTPELF 840 QTSRVSTGSL RYYGLGLENG LYTVTLHFAE TVYKSRTSQT WQSLGRRVFD IYIQGTRKMK 900 DFDISKEAGG VNRAVVRKFN VSVSENYLEI HLFWAGKGTC CIPNYGDYGP LIAVVHAASV 960 SGLPPTTPGK KSRTGLIVGI AVPVGV |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
PLN00113 | PLN00113 | 1.0e-19 | 480 | 677 | 198 | + leucine-rich repeat receptor-like protein kinase; Provisional | ||
PLN00113 | PLN00113 | 3.0e-21 | 464 | 734 | 282 | + leucine-rich repeat receptor-like protein kinase; Provisional | ||
PLN00113 | PLN00113 | 2.0e-25 | 480 | 677 | 199 | + leucine-rich repeat receptor-like protein kinase; Provisional | ||
pfam11721 | Malectin | 3.0e-49 | 202 | 388 | 190 | + Di-glucose binding within endoplasmic reticulum. Malectin is a membrane-anchored protein of the endoplasmic reticulum that recognises and binds Glc2-N-glycan. It carries a signal peptide from residues 1-26, a C-terminal transmembrane helix from residues 255-274, and a highly conserved central part of approximately 190 residues followed by an acidic, glutamate-rich region. Carbohydrate-binding is mediated by the four aromatic residues, Y67, Y89, Y116, and F117 and the aspartate at D186. NMR-based ligand-screening studies has shown binding of the protein to maltose and related oligosaccharides, on the basis of which the protein has been designated "malectin", and its endogenous ligand is found to be Glc2-high-mannose N-glycan. | ||
pfam11721 | Malectin | 5.0e-53 | 770 | 953 | 186 | + Di-glucose binding within endoplasmic reticulum. Malectin is a membrane-anchored protein of the endoplasmic reticulum that recognises and binds Glc2-N-glycan. It carries a signal peptide from residues 1-26, a C-terminal transmembrane helix from residues 255-274, and a highly conserved central part of approximately 190 residues followed by an acidic, glutamate-rich region. Carbohydrate-binding is mediated by the four aromatic residues, Y67, Y89, Y116, and F117 and the aspartate at D186. NMR-based ligand-screening studies has shown binding of the protein to maltose and related oligosaccharides, on the basis of which the protein has been designated "malectin", and its endogenous ligand is found to be Glc2-high-mannose N-glycan. |
Gene Ontology | |
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GO Term | Description |
GO:0005515 | protein binding |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI39026.1 | 0 | 13 | 408 | 206 | 636 | unnamed protein product [Vitis vinifera] |
EMBL | CBI39026.1 | 0.0000002 | 14 | 181 | 135 | 305 | unnamed protein product [Vitis vinifera] |
EMBL | CBI39026.1 | 0.0002 | 25 | 178 | 101 | 229 | unnamed protein product [Vitis vinifera] |
EMBL | CBI39026.1 | 0 | 403 | 972 | 42 | 638 | unnamed protein product [Vitis vinifera] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3rj0_A | 3e-25 | 467 | 722 | 288 | 569 | A Chain A, Human Liver Glycogen Phosphorylase (Tense State) In Complex With The Allosteric Inhibitor Ave5688 |
PDB | 3rj0_A | 7e-25 | 472 | 734 | 393 | 703 | A Chain A, Human Liver Glycogen Phosphorylase (Tense State) In Complex With The Allosteric Inhibitor Ave5688 |
PDB | 3rj0_A | 2e-24 | 471 | 726 | 416 | 719 | A Chain A, Human Liver Glycogen Phosphorylase (Tense State) In Complex With The Allosteric Inhibitor Ave5688 |
PDB | 3rj0_A | 7e-24 | 468 | 725 | 241 | 528 | A Chain A, Human Liver Glycogen Phosphorylase (Tense State) In Complex With The Allosteric Inhibitor Ave5688 |
PDB | 3rj0_A | 2e-21 | 467 | 737 | 217 | 516 | A Chain A, Human Liver Glycogen Phosphorylase (Tense State) In Complex With The Allosteric Inhibitor Ave5688 |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
CO865700 | 209 | 200 | 408 | 0 |
CO865700 | 227 | 767 | 986 | 0 |
DY268712 | 293 | 403 | 669 | 0 |
DY268712 | 118 | 13 | 130 | 8e-33 |
DY268712 | 128 | 21 | 148 | 0.000009 |
Sequence Alignments (This image is cropped. Click for full image.) |
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