Basic Information | |
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Species | Malus domestica |
Cazyme ID | MDP0000207612 |
Family | GT47 |
Protein Properties | Length: 662 Molecular Weight: 75511.1 Isoelectric Point: 8.6277 |
Chromosome | Chromosome/Scaffold: 015784307 Start: 3209 End: 5646 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 331 | 613 | 0 |
LKVYIYSEGEKPVFHQPLMRGIYASEGWFMKLIEGNKKFVVRDPXKAHXFYLPFDSHMLRLTIPRHSIHGKSKTVLEEVLQSYVGLISRKYPFWNRTKGA DHFLVACHDWAPKLTKQCMKNCIRSLCNAHVDREFEIGKDTSLPVTYIRSVENPLQDLGGKPASERSILAFFAGGLHGYLRPILLHYWANKEPDMKIFGP MPHDIEGKRMYREYMKSSKFCICARGYEVHTPRIVEAIFYECVPVIISDSYMPPFFEVFNWEAFAVFIQERDIPNLRNILLSI |
Full Sequence |
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Protein Sequence Length: 662 Download |
MDAAAARTQR FWNIGIRRLL LXIGXAVAIV VVSQCFELPY DTTFFFFPAD IGSISTATMF 60 ANVGSSNMSK SGXFSVGGVE GXVGNDTEVS DSEEEXRHGN DTRQQTWVYG LALGNDSSXT 120 GESMLENNVT LGKSYPVGTG GNEDGIFIRG KTDFXNGYLQ TANESVXGYR EDNXPGISSG 180 LKVNEVRNEV GLVPVVSQES STKRPENLNV DSKGNVEQNT ETQIDHQKIE LQQPVSVTLD 240 DNSTMTVDSV LRKWNRRPTS ISQXNSLLLQ SAVSSRSMKL RRYSARDREL QSAKLEIENA 300 PIIXDNAGLS ASVFRNLSKF IRSYDLMGHM LKVYIYSEGE KPVFHQPLMR GIYASEGWFM 360 KLIEGNKKFV VRDPXKAHXF YLPFDSHMLR LTIPRHSIHG KSKTVLEEVL QSYVGLISRK 420 YPFWNRTKGA DHFLVACHDW APKLTKQCMK NCIRSLCNAH VDREFEIGKD TSLPVTYIRS 480 VENPLQDLGG KPASERSILA FFAGGLHGYL RPILLHYWAN KEPDMKIFGP MPHDIEGKRM 540 YREYMKSSKF CICARGYEVH TPRIVEAIFY ECVPVIISDS YMPPFFEVFN WEAFAVFIQE 600 RDIPNLRNIL LSIPEDKYLT MMSRIKMVQQ HFFWHKKPKK YDLFHMVLHS VWYNRILQLK 660 TR |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 9.0e-59 | 327 | 613 | 307 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CAN76867.1 | 0 | 5 | 660 | 4 | 711 | hypothetical protein [Vitis vinifera] |
EMBL | CAN76867.1 | 0 | 278 | 658 | 1012 | 1390 | hypothetical protein [Vitis vinifera] |
EMBL | CBI28021.1 | 0 | 17 | 662 | 16 | 665 | unnamed protein product [Vitis vinifera] |
RefSeq | XP_002280595.1 | 0 | 17 | 662 | 14 | 663 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002281263.1 | 0 | 11 | 662 | 8 | 669 | PREDICTED: hypothetical protein [Vitis vinifera] |