Basic Information | |
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Species | Populus trichocarpa |
Cazyme ID | Potri.019G086800.1 |
Family | GT47 |
Protein Properties | Length: 477 Molecular Weight: 54054.2 Isoelectric Point: 9.5709 |
Chromosome | Chromosome/Scaffold: 19 Start: 11884151 End: 11887099 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 53 | 401 | 0 |
QNSIKVYVADLPRSLNYGLLDQYWSSSIPDTRISSDPDHQIRPKPTKNQKFLDYPENPLIKQYSAEYWITGDLMTPEKLKFRSFAKRVFDCNEADVVFVP FFATLSAEMELAKGKGSFRRKEGNEDYRRQKQVVDIVRNSDAWKRSGGKDHVFVLTDPVAMWHLRAEIAPAILLVVDFGGWYRLDSKSSNGSSSDMIQHT QVSLLKDVIVPYTHLLPRLQLSENKKRSTLLYFKGAKHRHRGGIVREKLWDLLVNEPGVIIEEGFPNATGREQSIRGMRSSEFCLHPAGDTPSSCRLFDA IQSLCIPVVVSDNIELPFEGMVDYTEFAVFVAVDDALKPRWLVDRLRSI |
Full Sequence |
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Protein Sequence Length: 477 Download |
MPPPKTTTTT LPCSIPTLFL AFTTLSFLCF SLFFLYNKNP SFPNPQTTLQ TSQNSIKVYV 60 ADLPRSLNYG LLDQYWSSSI PDTRISSDPD HQIRPKPTKN QKFLDYPENP LIKQYSAEYW 120 ITGDLMTPEK LKFRSFAKRV FDCNEADVVF VPFFATLSAE MELAKGKGSF RRKEGNEDYR 180 RQKQVVDIVR NSDAWKRSGG KDHVFVLTDP VAMWHLRAEI APAILLVVDF GGWYRLDSKS 240 SNGSSSDMIQ HTQVSLLKDV IVPYTHLLPR LQLSENKKRS TLLYFKGAKH RHRGGIVREK 300 LWDLLVNEPG VIIEEGFPNA TGREQSIRGM RSSEFCLHPA GDTPSSCRLF DAIQSLCIPV 360 VVSDNIELPF EGMVDYTEFA VFVAVDDALK PRWLVDRLRS ISVKQRNEFR RNMAKVQPIL 420 QYDNGHPGGI GPISPDGAVN HIWKKVLQKL PAIKEAVVRE RRKPPGVSVP LRCHCT* 480 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 7.0e-60 | 52 | 401 | 362 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_564443.1 | 0 | 41 | 475 | 42 | 476 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002270238.1 | 0 | 7 | 476 | 9 | 440 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002325567.1 | 0 | 1 | 476 | 1 | 476 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002327326.1 | 0 | 28 | 476 | 1 | 449 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002533317.1 | 0 | 38 | 476 | 37 | 478 | catalytic, putative [Ricinus communis] |