| Basic Information | |
|---|---|
| Species | Sorghum bicolor |
| Cazyme ID | Sb01g036460.2 |
| Family | GT57 |
| Protein Properties | Length: 498 Molecular Weight: 56245.6 Isoelectric Point: 9.5128 |
| Chromosome | Chromosome/Scaffold: 1 Start: 60060114 End: 60063177 |
| Description | ALG6, ALG8 glycosyltransferase family |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT57 | 352 | 477 | 8.5e-25 |
| IHEKSILLPLLPASLLALEEPRMYGWFVYFALFSMYPLICRDQLLLQYIAVLGLFFLIHYSPGGSYGKRSNMSCRAKLVLSLPFLCSLLLHITYLQIEPP NRYPFLFDALIMFVCFSQFVILALYT | |||
| GT57 | 41 | 351 | 0 |
| LLVRVLVSVGPYSGQGAAPKFGDYEAQRHWMELTLHLTPSDWYRNTSDNDLAYWGLDYPPLSAYQSLLHGRIINASLPEAVALRSSRGYESMESKLLMRW TVLSSDLLVFFPAALWFVWAYMKVGIGISGEERREGWMWLLAMVLISPCLVLIDHGHFQYNCISLGLTLGATAGVLSRNELVAAALFTLAINHKQMSLYF APAFFSHLLGKCLKRKHPIVEVTKLAFVVLGTFALVWWPFLHSYEAALQVISRLAPFERGIYEDYVANFWCSTSVIIKWKKLFAIKPLKLMSLSATILAF LPSFVQQVKSP | |||
| Full Sequence |
|---|
| Protein Sequence Length: 498 Download |
| MAKPRKPRTL APDPSVAAAR LPWHPPAPPV PTAVLISLAA LLVRVLVSVG PYSGQGAAPK 60 FGDYEAQRHW MELTLHLTPS DWYRNTSDND LAYWGLDYPP LSAYQSLLHG RIINASLPEA 120 VALRSSRGYE SMESKLLMRW TVLSSDLLVF FPAALWFVWA YMKVGIGISG EERREGWMWL 180 LAMVLISPCL VLIDHGHFQY NCISLGLTLG ATAGVLSRNE LVAAALFTLA INHKQMSLYF 240 APAFFSHLLG KCLKRKHPIV EVTKLAFVVL GTFALVWWPF LHSYEAALQV ISRLAPFERG 300 IYEDYVANFW CSTSVIIKWK KLFAIKPLKL MSLSATILAF LPSFVQQVKS PIHEKSILLP 360 LLPASLLALE EPRMYGWFVY FALFSMYPLI CRDQLLLQYI AVLGLFFLIH YSPGGSYGKR 420 SNMSCRAKLV LSLPFLCSLL LHITYLQIEP PNRYPFLFDA LIMFVCFSQF VILALYTNYK 480 QWMLDTHSRS IGVKKDL* 540 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03155 | Alg6_Alg8 | 2.0e-88 | 50 | 479 | 466 | + ALG6, ALG8 glycosyltransferase family. N-linked (asparagine-linked) glycosylation of proteins is mediated by a highly conserved pathway in eukaryotes, in which a lipid (dolichol phosphate)-linked oligosaccharide is assembled at the endoplasmic reticulum membrane prior to the transfer of the oligosaccharide moiety to the target asparagine residues. This oligosaccharide is composed of Glc(3)Man(9)GlcNAc(2). The addition of the three glucose residues is the final series of steps in the synthesis of the oligosaccharide precursor. Alg6 transfers the first glucose residue, and Alg8 transfers the second one. In the human alg6 gene, a C->T transition, which causes Ala333 to be replaced with Val, has been identified as the cause of a congenital disorder of glycosylation, designated as type Ic OMIM:603147. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0005789 | endoplasmic reticulum membrane |
| GO:0016758 | transferase activity, transferring hexosyl groups |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| DDBJ | BAC79743.1 | 0 | 1 | 497 | 1 | 517 | putative alpha 3 glucosyltransferase [Oryza sativa Japonica Group] |
| RefSeq | NP_001058960.1 | 0 | 1 | 452 | 109 | 569 | Os07g0164500 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | NP_001145139.1 | 0 | 1 | 497 | 1 | 519 | hypothetical protein LOC100278369 [Zea mays] |
| RefSeq | XP_002280181.1 | 0 | 36 | 497 | 36 | 515 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002329281.1 | 0 | 44 | 497 | 11 | 485 | predicted protein [Populus trichocarpa] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| dolichyl-diphosphooligosaccharide biosynthesis | RXN-5470 | EC-2.4.1.267 | Dol-P-Glc:Man9GlcNAc2-PP-Dol α-1,3-glucosyltransferase |
