| Basic Information | |
|---|---|
| Species | Setaria italica |
| Cazyme ID | Si005663m |
| Family | GT48 |
| Protein Properties | Length: 1931 Molecular Weight: 222913 Isoelectric Point: 9.4224 |
| Chromosome | Chromosome/Scaffold: 4 Start: 40020270 End: 40033905 |
| Description | glucan synthase-like 12 |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GT48 | 1066 | 1350 | 0 |
| VPTNLDARRRISFFANSLFMEMPNAPKVRNMLPFSVLTPYYKEDVLFSSQNLEEPNEDGVSILFYLQKIYPDEWKNFLERVDRKSEEELREDEELEEELR LWASYRGQTLTRTVRGMMYYRKALELQAFLDMAQDDDLMEGYRATELMSEDSQLMTQCKAIADMKFTYVVSCQQYGIQKRSGEPCAHDILRLMTTYPSLR VAYIDEVEAPSQDRNKKVEKVYYSALVKASVTKPNEPGQSLDQVIYKIKLPGNAILGEGKPENQNHAIIFTRGECLQTIDMNQMH | |||
| GT48 | 1357 | 1786 | 0 |
| HVSSLAWFMSNQETSFVTIGQRVLANPLRVRFHYGHPDIFDRLFHLTRGGVSKASKIINLSEDIFAGFNSTLREGNVTHHEYMQVGKGRDVGLNQISLFE AKIANGNGEQTLSRDIYRLGHRFDFFRMLSCYYTTIGFYFSTMITVWTVYVFLYGRLYLVLSGLDEALATGRRFVHNTPLQVALASESFVQLGFLMALPM MMEIGLERGFRTALSDFVLMQLQLASVFFTFSLGTKTHYYGKTLLHGGAEYRATGRGFVVFHAKFADNYRLYSRSHFVKGIELMILLVVFEIFGQSYRGA ITYIFITISMWFMVGTWLFAPFLFNPSGFEWQKIVDDWTDWHKWISNRGGIGVAPEKSWESWWDKEQEPLRHSGKRGTIVEILLALRFFIYQYGLVYHLN ITKKITKDTHSVLVYCFSWVVIFVILLVMK | |||
| Full Sequence |
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| Protein Sequence Length: 1931 Download |
| MAAPGRRPDM SSSSPSPSPA APPSSGRRLL RTQTVGNLGE SIFDSEVVPS SLVEIAPILR 60 VANEVEATNP RVAYLCRFYA FEKAHRLDPT SSGRGVRQFK TALLQRLERE NDPTLKGRVH 120 QSDAREMQRF YREYYKKYIQ ALQNAADKAD RALLTKAYQT AAVLFEVLRA VNVSQSVEVD 180 QAILDTHNKV EEKKKLYVPY NILPLDPEST NQAIMRYPEI QAAVYALRNI RGLPWPKDHE 240 KKPDDKNTGK DLLDWLQGMF GFQKDNVSNQ REHLILLLAN VHVRKIPKAE QQPKLDDQAL 300 DAVMKKLFKN YKKWCKYLGR KSSLWLPTIQ QEVQQRKLLY MGLYLLIWGE AANLRFMPEC 360 LCYIYHHMAF ELYGMLAGNV SPMTGENVKP AYGGDEEAFL MKVVTPIYKV IEKEAERSKT 420 IKSKHSHWRN YDDLNEYFWS VDCFRLGWPM RADADFFKTP KDAYPNRLNG ENTSVGSVHW 480 MGKVNFVEIR SFWHIFRSFD RMWIFLILSL QAMIILAWNG GTPSDIFDTK VFKQVLSIFI 540 TAAVLKLGQA LLDIIFGWKA RRSMSFAVKL RYVLKLISAA AWVVILPVTY AYTWENPTGL 600 ARTIKSWLGG GQNQPSLYIL AVVVYLAPNM LASMLFLFPF LRRYLESSNV KVITFMMWWS 660 QPRLFVGRGM HEGAFSLFKY TMFWVLLLAM KLTVSFYIEI KPLVQPTKDI MREPIRTFQW 720 HEFFPHGSNN IGVVIALWAP IILVYFMDTQ IWYALFSTLI GGIYGAYRRL GEIRTLGMLR 780 SRFESLPVAF NERLIPSDAN KRKGLRAAFS RKPKASDDEK EEEKRAARFA QMWNLIITSF 840 REEDLIDNRE MDLLLVPYCK DRELNIFQWP PFLLASKIPI ALDMAADSGG KDRDLTKRMG 900 SDPYFSYAIR ECYASFKNII NTLVFGQREK LVIKEIFDVV DKHIAEETLI RDLTMRSLPA 960 LSKKFIDLLE LLQKNKEEDL GQVVILFQDM LEVVTRDIME EEQLGGMLES IHGGHNRRHE 1020 GITPLDQQDQ LFAKAIRFPM EESDAWTEKI KRLHLLLTVK ESAMDVPTNL DARRRISFFA 1080 NSLFMEMPNA PKVRNMLPFS VLTPYYKEDV LFSSQNLEEP NEDGVSILFY LQKIYPDEWK 1140 NFLERVDRKS EEELREDEEL EEELRLWASY RGQTLTRTVR GMMYYRKALE LQAFLDMAQD 1200 DDLMEGYRAT ELMSEDSQLM TQCKAIADMK FTYVVSCQQY GIQKRSGEPC AHDILRLMTT 1260 YPSLRVAYID EVEAPSQDRN KKVEKVYYSA LVKASVTKPN EPGQSLDQVI YKIKLPGNAI 1320 LGEGKPENQN HAIIFTRGEC LQTIDMNQMH WEKRVNHVSS LAWFMSNQET SFVTIGQRVL 1380 ANPLRVRFHY GHPDIFDRLF HLTRGGVSKA SKIINLSEDI FAGFNSTLRE GNVTHHEYMQ 1440 VGKGRDVGLN QISLFEAKIA NGNGEQTLSR DIYRLGHRFD FFRMLSCYYT TIGFYFSTMI 1500 TVWTVYVFLY GRLYLVLSGL DEALATGRRF VHNTPLQVAL ASESFVQLGF LMALPMMMEI 1560 GLERGFRTAL SDFVLMQLQL ASVFFTFSLG TKTHYYGKTL LHGGAEYRAT GRGFVVFHAK 1620 FADNYRLYSR SHFVKGIELM ILLVVFEIFG QSYRGAITYI FITISMWFMV GTWLFAPFLF 1680 NPSGFEWQKI VDDWTDWHKW ISNRGGIGVA PEKSWESWWD KEQEPLRHSG KRGTIVEILL 1740 ALRFFIYQYG LVYHLNITKK ITKDTHSVLV YCFSWVVIFV ILLVMKTVSV GRRRFSAEFQ 1800 LVFRLIKGLI FITFTSIVII LIAIPGMTVL DIFVCILAFM PTGWGLLLIA QAIRPVIQKI 1860 GLWGSIKALA RGYEILMGLL LFTPIAFLAW FPFVSEFQTR MLFNQAFSRG LQISRILGGH 1920 KKDRATRNKE * |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam04652 | DUF605 | 1.0e-9 | 55 | 169 | 122 | + Vta1 like. Vta1 (VPS20-associated protein 1) is a positive regulator of Vps4. Vps4 is an ATPase that is required in the multivesicular body (MVB) sorting pathway to dissociate the endosomal sorting complex required for transport (ESCRT). Vta1 promotes correct assembly of Vps4 and stimulates its ATPase activity through its conserved Vta1/SBP1/LIP5 region. | ||
| pfam14288 | FKS1_dom1 | 1.0e-55 | 335 | 451 | 118 | + 1,3-beta-glucan synthase subunit FKS1, domain-1. The FKS1_dom1 domain is likely to be the 'Class I' region just N-terminal to the first set of transmembrane helices that is involved in 1,3-beta-glucan synthesis itself. This family is found on proteins with family Glucan_synthase, pfam02364. | ||
| pfam02364 | Glucan_synthase | 0 | 1066 | 1782 | 821 | + 1,3-beta-glucan synthase component. This family consists of various 1,3-beta-glucan synthase components including Gls1, Gls2 and Gls3 from yeast. 1,3-beta-glucan synthase EC:2.4.1.34 also known as callose synthase catalyzes the formation of a beta-1,3-glucan polymer that is a major component of the fungal cell wall. The reaction catalyzed is:- UDP-glucose + {(1,3)-beta-D-glucosyl}(N) <=> UDP + {(1,3)-beta-D-glucosyl}(N+1). | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0000148 | 1,3-beta-D-glucan synthase complex |
| GO:0003843 | 1,3-beta-D-glucan synthase activity |
| GO:0006075 | (1->3)-beta-D-glucan biosynthetic process |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| DDBJ | BAD23015.1 | 0 | 27 | 1930 | 35 | 1969 | putative callose synthase 1 catalytic subunit [Oryza sativa Japonica Group] |
| DDBJ | BAD62105.1 | 0 | 1 | 1930 | 1 | 1959 | putative callose synthase 1 catalytic subunit [Oryza sativa Japonica Group] |
| GenBank | EEE58116.1 | 0 | 27 | 1930 | 35 | 1918 | hypothetical protein OsJ_09005 [Oryza sativa Japonica Group] |
| RefSeq | XP_002439067.1 | 0 | 1 | 1930 | 1 | 1965 | hypothetical protein SORBIDRAFT_10g030970 [Sorghum bicolor] |
| RefSeq | XP_002453103.1 | 0 | 20 | 1930 | 19 | 1942 | hypothetical protein SORBIDRAFT_04g038510 [Sorghum bicolor] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2lxm_A | 0.008 | 59 | 168 | 21 | 128 | B Chain B, Lip5-chmp5 |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| callose biosynthesis | 13-BETA-GLUCAN-SYNTHASE-RXN | EC-2.4.1.34 | 1,3-β-glucan synthase |
| Transmembrane Domains | |
|---|---|
 | |
| Start | End |
| 502 | 521 |
| 536 | 558 |
| 570 | 592 |
| 619 | 641 |
| 676 | 698 |
| 724 | 746 |
| 751 | 768 |
| 1488 | 1510 |
| 1536 | 1558 |
| 1573 | 1590 |
| 1627 | 1649 |
| 1659 | 1681 |
| 1735 | 1757 |
| 1767 | 1789 |
| 1802 | 1824 |
| 1829 | 1851 |
| 1872 | 1894 |
| Hydropathy |
|---|
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